iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-021197

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017692

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000009375.3	ENSCAFT00000039730.2	ENSCAFP00000035619.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-41	136.3	11	43
E3 activity/RING/U-box	3.60e-25	88.1	404	475
UBD/Beta-Prp	3.10e-54	184.5	8	220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l++++
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFT 43
           9*********548***************98876 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM+dPv++++G++y+++++e w++++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMKDPVIASDGYSYEKEAMENWISKKKRTSPMTNLILPSMVLTPNRTLKMAISRWLETHQ 475
           8********************************************************************997 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk 91
           l +h ++ ++c +f  ++sllat s d+ti+++++++ +    + l+ h+ +v +++fsp+g +l+++s+D+t  +w+ ++g+++ +++
   Q: 8    LADHGDD-VNCCAF--SSSLLATCSLDKTIRLYSLSDFTElpHSPLKFHTYAVHCCCFSPSGHVLASCSTDGTTVLWNTQNGETLAVME 93
           5555555.556899..9*******************9666667889******************************************9 PP
   S: 92   ghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           + + + v+ ++fsp++  lvsG +d t+ +w+ ++++ ++ + s++dg+    +++p+gn +v+Gs  + + +Wd   +++l+  +  h
   Q: 94   QPTgSPVRVCQFSPDSTCLVSGAADGTVVLWNAQSYKLYR-CGSVKDGSLVACAFSPNGNFFVTGSSCGDITVWDD-KMRCLHSEKA-H 179
           765267*********************************9.**********************************8.6678888877.* PP
   S: 180  tdsvyslsfdsng..........kelvsgsldgtvklwdlq 210
           +  +++ +f+s+           ++l+s+++d ++k+w ++
   Q: 180  DLGITCCDFSSQPvsdgeqglqfFRLASCGQDCQIKIWVVS 220
           ********9998899999********************776 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFTELPHSPL KFHTYAVHCC 60
CFSPSGHVLA SCSTDGTTVL WNTQNGETLA VMEQPTGSPV RVCQFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAC TAATTCACAC ATTGGCGGAT CACGGAGATG ATGTCAACTG CTGTGCGTTC 60
TCCTCTTCCC TCTTGGCTAC TTGCTCTTTG GACAAAACAA TTCGCCTGTA CTCCCTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cfa:478761

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	54.55	3.00e-17	84.00
IUUC-Aml-001614	Ailuropoda melanoleuca	95.80	0.00e+00	954.00
IUUC-Apl-003529	Anas platyrhynchos	75.42	0.00e+00	764.00
IUUC-Aca-004257	Anolis carolinensis	69.82	0.00e+00	701.00
IUUC-Ame-011357	Astyanax mexicanus	52.51	2.00e-118	419.00
IUUC-Bta-013032	Bos taurus	88.26	0.00e+00	882.00
IUUC-Cja-018743	Callithrix jacchus	90.97	0.00e+00	914.00
IUUC-Cpo-022279	Cavia porcellus	87.82	0.00e+00	890.00
IUUC-Csa-023954	Chlorocebus sabaeus	92.02	0.00e+00	920.00
IUUC-Cho-025083	Choloepus hoffmanni	72.49	8.00e-156	543.00
IUUC-Cin-025786	Ciona intestinalis	35.28	4.00e-80	291.00
IUUC-Dre-028087	Danio rerio	56.58	2.00e-144	505.00
IUUC-Dno-028919	Dasypus novemcinctus	91.39	0.00e+00	915.00
IUUC-Dor-031112	Dipodomys ordii	86.55	0.00e+00	868.00
IUUC-Ete-032405	Echinops telfairi	87.17	0.00e+00	635.00
IUUC-Eca-033254	Equus caballus	90.13	0.00e+00	901.00
IUUC-Eeu-034545	Erinaceus europaeus	85.92	0.00e+00	839.00
IUUC-Fca-035482	Felis catus	94.96	0.00e+00	948.00
IUUC-Fal-036976	Ficedula albicollis	60.49	3.00e-162	565.00
IUUC-Gmo-039213	Gadus morhua	54.83	2.00e-138	485.00
IUUC-Gga-040561	Gallus gallus	74.84	0.00e+00	753.00
IUUC-Gac-041471	Gasterosteus aculeatus	58.19	6.00e-143	500.00
IUUC-Ggo-045503	Gorilla gorilla	92.02	0.00e+00	923.00
IUUC-Hsa-045910	Homo sapiens	92.23	0.00e+00	926.00
IUUC-Hvu-047757	Hordeum vulgare	46.15	3.00e-19	90.90
IUUC-Itr-048214	Ictidomys tridecemlineatus	88.33	0.00e+00	704.00
IUUC-Loc-052307	Lepisosteus oculatus	59.72	5.00e-169	587.00
IUUC-Laf-053587	Loxodonta africana	90.34	0.00e+00	907.00
IUUC-Mcc-055679	Macaca mulatta	92.23	0.00e+00	924.00
IUUC-Meu-055962	Macropus eugenii	70.80	0.00e+00	657.00
IUUC-Mga-059652	Meleagris gallopavo	74.21	0.00e+00	753.00
IUUC-Mmr-060943	Microcebus murinus	88.91	0.00e+00	892.00
IUUC-Mdo-062592	Monodelphis domestica	82.67	0.00e+00	834.00
IUUC-Mmu-063577	Mus musculus	80.67	0.00e+00	813.00
IUUC-Mpu-066422	Mustela putorius furo	94.54	0.00e+00	940.00
IUUC-Mlu-067250	Myotis lucifugus	89.92	0.00e+00	897.00
IUUC-Nle-069517	Nomascus leucogenys	91.81	0.00e+00	923.00
IUUC-Opr-070776	Ochotona princeps	88.66	0.00e+00	884.00
IUUC-Ont-071821	Oreochromis niloticus	57.32	1.00e-151	529.00
IUUC-Oan-073706	Ornithorhynchus anatinus	82.11	0.00e+00	832.00
IUUC-Ocu-074766	Oryctolagus cuniculus	81.88	0.00e+00	801.00
IUUC-Ola-086531	Oryzias latipes	56.63	3.00e-146	511.00
IUUC-Oga-088388	Otolemur garnettii	88.03	0.00e+00	889.00
IUUC-Oar-089748	Ovis aries	88.89	0.00e+00	884.00
IUUC-Ptr-090616	Pan troglodytes	91.75	0.00e+00	915.00
IUUC-Pan-091769	Papio anubis	91.28	0.00e+00	659.00
IUUC-Psi-093334	Pelodiscus sinensis	77.73	0.00e+00	736.00
IUUC-Pma-094383	Petromyzon marinus	48.05	2.00e-131	462.00
IUUC-Pfo-096801	Poecilia formosa	56.16	3.00e-148	518.00
IUUC-Pab-098139	Pongo abelii	90.72	0.00e+00	742.00
IUUC-Pca-100523	Procavia capensis	76.26	0.00e+00	736.00
IUUC-Pva-102286	Pteropus vampyrus	89.71	0.00e+00	870.00
IUUC-Rno-104831	Rattus norvegicus	83.61	0.00e+00	843.00
IUUC-Sha-107499	Sarcophilus harrisii	83.82	0.00e+00	849.00
IUUC-Sar-113389	Sorex araneus	86.34	0.00e+00	840.00
IUUC-Tgu-116769	Taeniopygia guttata	73.11	0.00e+00	730.00
IUUC-Tru-118774	Takifugu rubripes	53.50	1.00e-139	489.00
IUUC-Tsy-119595	Tarsius syrichta	79.56	0.00e+00	643.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.78	3.00e-148	518.00
IUUC-Tur-126683	Triticum urartu	53.03	5.00e-17	83.60
IUUC-Tbe-127938	Tupaia belangeri	79.67	1.00e-144	505.00
IUUC-Ttr-128193	Tursiops truncatus	91.04	0.00e+00	772.00
IUUC-Vpa-130275	Vicugna pacos	92.02	0.00e+00	919.00
IUUC-Xtr-131982	Xenopus tropicalis	60.21	7.00e-170	590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence