iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000005832.1	ENSORLT00000007337.1	ENSORLP00000007336.1
ENSORLG00000005832.1	ENSORLT00000007339.1	ENSORLP00000007338.1
ENSORLG00000005832.1	ENSORLT00000007340.1	ENSORLP00000007339.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-15	56.7	115	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGd++ v    ++++gW++g   l+gk G fP+n+v++l+
   Q: 115  LVKARFPFQQTNEDELSFSKGDIIVV--RRQEEGGWWEG--SLNGKTGWFPSNYVRELK 169
           68999*******************99..6999*******..9**************986 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

KLQFFPEPRS DSDFQKNIAE FLKGLAAFGV EPFEVSDLLQ GFNFSKVLNS LVALNKATEG 60
LGVSGDDGGG APHSSASSRI KSFDSLNTQG RSSKLLLPQY RSLDMSEGSG CGQPLVKARF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG CAGAGCAGAC GGTAACGTGG CTCATTACTC TCGGAGTTCT GGAGTCTCCG 60
AAGAAGAGCG TCTCAGATCC GGAGGCTTTC CTGCAGACGT CGCTGCGGGA TGGAGCGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0001525--P:angiogenesis
GO:0001935--P:endothelial cell proliferation
GO:0055113--P:epiboly involved in gastrulation with mouth forming second
GO:0071896--P:protein localization to adherens junction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000307	Aegilops tauschii	32.10	6.90e-01	28.90
IUUC-Aly-005591	Arabidopsis lyrata	47.73	4.00e-09	55.50
IUUC-Bdi-014394	Brachypodium distachyon	48.94	2.00e-09	56.60
IUUC-Gac-041950	Gasterosteus aculeatus	75.19	0.00e+00	1103.00
IUUC-Hvu-047839	Hordeum vulgare	51.06	1.00e-09	55.50
IUUC-Mtr-058576	Medicago truncatula	58.82	3.00e-13	69.30
IUUC-Ont-072325	Oreochromis niloticus	82.67	0.00e+00	1257.00
IUUC-Obr-076390	Oryza brachyantha	48.94	7.00e-09	54.70
IUUC-Pfo-096932	Poecilia formosa	81.97	0.00e+00	1251.00
IUUC-Pca-100997	Procavia capensis	46.35	6.00e-151	528.00
IUUC-Ptt-103726	Puccinia triticina	40.00	2.00e-10	58.90
IUUC-Tru-118301	Takifugu rubripes	80.97	0.00e+00	1190.00
IUUC-Tni-120394	Tetraodon nigroviridis	80.98	0.00e+00	1088.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence