iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-017376

Ensembl Protein ID

Bra029461.1-P

UniProt Accession

M4EKZ4; M4EKZ4_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra029461	Bra029461.1	Bra029461.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.60e-94	316.9	547	880
ULD/UDP/UBQ/UBQ_PIM	6.60e-15	55.8	105	178

Active Site

Position(s)	Description	Evidence
849	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfykl 99
           +l++ l++ef++Ee+++  Gv re+++l+++e++np + lfl+s++d + ++pnp+s++ +p hl++Fef Gr++++al+++  + + + ++f+++
   Q: 547  SLHSGLFMEFKNEEATGP-GVLREWFYLVCQEIFNPRNALFLRSADDFRRFSPNPASKV-DPLHLSYFEFTGRVIALALMHKVQVGVLFDRVFFSQ 640
           678899***********9.***************************************9.68********************************** PP
   S: 100  llgkklsledleevdpelykslkeikena.esdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafr 194
           l + ++sled++++d+ +y+s k+i+e++     +++gl ltf+ ++e+lg+++++eL+p+G++i V+ eN+e+Yvkl+++ r+  +i ++ve f+
   Q: 641  LAHPEISLEDIKDTDRVMYNSCKQILEMDpAFFDSNAGLGLTFELETEELGKRETVELLPDGRSIAVNSENREQYVKLLIKQRFAASISQHVERFS 736
           *********************99999998555778899********************************************************** PP
   S: 195  eGfneviplellslFte...eelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprl 286
           +Gf+++++ ++ + F+    e+++ ++ G  + i+++d+k++t+y+ g++e++++i+wFw++++++++eer+  L F+T+++ +P++Gf+ l+ +l
   Q: 737  KGFSDILSDSVPAFFKRiylEDFDGMLRGGeNPISIDDWKAHTEYN-GFKETDRQIDWFWKIMKKMTEEERRSVLFFWTSTKFIPVEGFRGLSSKL 831
           ******99998777765333888899998889*************5.5************************************************ PP
   S: 287  fvirkdasddrlPssnTCfnyLkLPeYsskeilkekLly.Aieet.kgF 333
           +++r  +++drlP+s+TCf++L+LP+Y+++  ++++L++ A ++  ++F
   Q: 832  YIYRLHEANDRLPTSHTCFYRLCLPKYPTMGLMEQRLRFiAQDHVsSSF 880
           *************************************751555555555 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 2    kltvktlkgke.felevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkks 74
           +l+v+ ++g + + ++++++dtve+l ++i+ ++++p+++q++Iy+Gk+L+ + tL+ + i+++s +hlv++ +
   Q: 105  QLFVRMMSGGKtIVIHADRNDTVEHLHHRIQLKTQIPVTEQRVIYKGKQLQFEHTLNHYSIEQDSSLHLVGRMQ 178
           788998888776889*******************************************************9976 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MTLRRSTAAD SPISHRSPLA VAGTDNHKRK LDDYAADYGL DLLQKMKRHE VDADRISPAS 60
QQKPLTSGEN YRSLYTPGEC SSSSSPSSSS SLPESWTRSE STRLQLFVRM MSGGKTIVIH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTCTAC GCCGTTCAAC AGCCGCAGAT TCACCAATCT CTCACCGATC ACCTCTCGCC 60
GTCGCTGGAA CCGATAACCA CAAACGCAAA CTCGACGATT ACGCCGCCGA TTACGGCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50237--HECT
PS50053--UBIQUITIN_2

Pfam

PF00632--HECT
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00119--HECTc
SM00213--UBQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000327	Aegilops tauschii	40.88	9.00e-147	514.00
IUUC-Atr-002891	Amborella trichopoda	40.21	6.00e-170	591.00
IUUC-Aly-005570	Arabidopsis lyrata	70.66	0.00e+00	1259.00
IUUC-Ath-007126	Arabidopsis thaliana	68.53	0.00e+00	1239.00
IUUC-Bdi-014613	Brachypodium distachyon	41.17	5.00e-161	561.00
IUUC-Bol-016237	Brassica oleracea	98.75	0.00e+00	1740.00
IUUC-Gma-043346	Glycine max	50.38	0.00e+00	808.00
IUUC-Hvu-047734	Hordeum vulgare	42.30	4.00e-160	558.00
IUUC-Lpe-051617	Leersia perrieri	40.15	1.00e-143	503.00
IUUC-Mtr-058709	Medicago truncatula	48.51	0.00e+00	727.00
IUUC-Mac-065415	Musa acuminata	43.07	5.00e-170	591.00
IUUC-Oba-075190	Oryza barthii	43.20	6.00e-137	481.00
IUUC-Obr-076197	Oryza brachyantha	41.76	2.00e-153	536.00
IUUC-Ogl-077892	Oryza glaberrima	39.14	2.00e-130	459.00
IUUC-Ogu-078711	Oryza glumaepatula	40.42	2.00e-139	490.00
IUUC-Oin-079504	Oryza indica	39.26	6.00e-135	474.00
IUUC-Olo-080730	Oryza longistaminata	43.20	9.00e-137	480.00
IUUC-Ome-081851	Oryza meridionalis	40.61	1.00e-142	500.00
IUUC-Oni-082230	Oryza nivara	40.42	2.00e-139	489.00
IUUC-Opu-084015	Oryza punctata	40.72	1.00e-141	497.00
IUUC-Oru-084327	Oryza rufipogon	40.42	2.00e-139	490.00
IUUC-Osa-086148	Oryza sativa	39.14	6.00e-131	461.00
IUUC-Ppa-095337	Physcomitrella patens	39.32	8.00e-163	567.00
IUUC-Pop-099556	Populus trichocarpa	45.81	0.00e+00	720.00
IUUC-Ppe-101443	Prunus persica	53.59	0.00e+00	844.00
IUUC-Smo-108789	Selaginella moellendorffii	39.31	7.00e-157	547.00
IUUC-Sit-110651	Setaria italica	40.64	2.00e-145	509.00
IUUC-Sly-111513	Solanum lycopersicum	45.96	0.00e+00	775.00
IUUC-Stu-112582	Solanum tuberosum	46.19	0.00e+00	779.00
IUUC-Sbi-114659	Sorghum bicolor	37.89	4.00e-111	395.00
IUUC-Tca-121392	Theobroma cacao	53.83	0.00e+00	850.00
IUUC-Tae-125860	Triticum aestivum	36.80	8.00e-129	454.00
IUUC-Tur-126774	Triticum urartu	43.27	3.00e-151	528.00
IUUC-Vvi-131149	Vitis vinifera	52.52	0.00e+00	822.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence