iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090620

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03121256

Gene Name

UBE2S

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000011507.3	ENSPTRT00000021446.3	ENSPTRP00000019791.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.80e-40	137.9	16	148

Active Site

Position(s)	Description	Evidence
94	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           +ke+++l++dpp+gi++ p++e dlt+++v+i+Gpe+tpY+gg+F++++ + +d+P++PPk  fltkifhPnv +nG++C+++lk  ++
   Q: 16   YKEVTTLTADPPDGIKVFPNEE-DLTDLQVTIEGPEGTPYAGGLFRMKLLLGKDFPASPPKGYFLTKIFHPNVGANGEICVNVLK--RD 101
           79********************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           W++ l +++vll+i+ ll +pnpes+lneea +ll +n eey  ++r
   Q: 102  WTAELGIRHVLLTIKCLLIHPNPESALNEEAGRLLLENYEEYAARAR 148
           ******************************************99876 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

NSNVENLPPH IIRLVYKEVT TLTADPPDGI KVFPNEEDLT DLQVTIEGPE GTPYAGGLFR 60
MKLLLGKDFP ASPPKGYFLT KIFHPNVGAN GEICVNVLKR DWTAELGIRH VLLTIKCLLI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCAGAACT CCAACGTGGA GAACCTACCC CCGCACATCA TCCGCCTGGT GTACAAGGAG 60
GTGACGACAC TGACCGCAGA CCCACCCGAT GGCATCAAGG TCTTTCCCAA CGAGGAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0070979--P:protein K11-linked ubiquitination
GO:0044314--P:protein K27-linked ubiquitination
GO:0035519--P:protein K29-linked ubiquitination
GO:0085020--P:protein K6-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000818	Aegilops tauschii	59.88	5.00e-50	190.00
IUUC-Aml-001979	Ailuropoda melanoleuca	94.06	1.00e-92	332.00
IUUC-Atr-002706	Amborella trichopoda	59.09	3.00e-48	184.00
IUUC-Aca-004432	Anolis carolinensis	77.00	2.00e-86	311.00
IUUC-Aly-005779	Arabidopsis lyrata	59.65	2.00e-58	218.00
IUUC-Ath-007162	Arabidopsis thaliana	60.23	2.00e-58	218.00
IUUC-Acl-008107	Aspergillus clavatus	50.40	3.00e-34	139.00
IUUC-Afl-008578	Aspergillus flavus	45.40	8.00e-35	141.00
IUUC-Afu-009034	Aspergillus fumigatus	52.34	5.00e-35	141.00
IUUC-Ani-009151	Aspergillus nidulans	51.94	4.00e-36	145.00
IUUC-Ang-009649	Aspergillus niger	50.77	3.00e-36	145.00
IUUC-Ame-010836	Astyanax mexicanus	60.08	1.00e-78	285.00
IUUC-Bta-012740	Bos taurus	100.00	2.00e-88	318.00
IUUC-Bdi-014057	Brachypodium distachyon	59.66	1.00e-50	192.00
IUUC-Bol-016481	Brassica oleracea	60.82	2.00e-58	218.00
IUUC-Bra-016867	Brassica rapa	60.23	2.00e-58	219.00
IUUC-Cja-019763	Callithrix jacchus	99.00	3.00e-106	377.00
IUUC-Cfa-020216	Canis familiaris	94.06	5.00e-94	336.00
IUUC-Cpo-021720	Cavia porcellus	90.05	2.00e-95	341.00
IUUC-Cre-022676	Chlamydomonas reinhardtii	60.93	2.00e-56	210.00
IUUC-Csa-023751	Chlorocebus sabaeus	99.50	2.00e-106	378.00
IUUC-Cho-024620	Choloepus hoffmanni	98.23	1.00e-63	234.00
IUUC-Cin-025632	Ciona intestinalis	63.16	2.00e-64	238.00
IUUC-Csv-025984	Ciona savignyi	66.67	2.00e-63	234.00
IUUC-Cne-026844	Cryptococcus neoformans	54.05	5.00e-48	184.00
IUUC-Cme-027294	Cyanidioschyzon merolae	57.69	2.00e-51	195.00
IUUC-Dre-027674	Danio rerio	62.55	5.00e-80	290.00
IUUC-Dno-029886	Dasypus novemcinctus	100.00	2.00e-88	318.00
IUUC-Dor-030440	Dipodomys ordii	94.06	3.00e-95	340.00
IUUC-Dse-031211	Dothistroma septosporum	47.06	2.00e-31	126.00
IUUC-Dme-031888	Drosophila melanogaster	67.53	4.00e-63	233.00
IUUC-Ete-032365	Echinops telfairi	80.35	2.00e-70	257.00
IUUC-Eca-033733	Equus caballus	95.54	9.00e-94	335.00
IUUC-Eeu-035342	Erinaceus europaeus	96.75	3.00e-86	310.00
IUUC-Fca-035964	Felis catus	100.00	9.00e-63	232.00
IUUC-Gmo-039357	Gadus morhua	80.49	4.00e-77	280.00
IUUC-Gga-040261	Gallus gallus	87.23	4.00e-47	180.00
IUUC-Gac-042593	Gasterosteus aculeatus	77.58	4.00e-76	277.00
IUUC-Gma-043597	Glycine max	57.95	1.00e-58	219.00
IUUC-Ggo-044626	Gorilla gorilla	100.00	1.00e-77	281.00
IUUC-Hsa-046058	Homo sapiens	99.50	2.00e-106	377.00
IUUC-Hvu-047281	Hordeum vulgare	59.65	2.00e-49	188.00
IUUC-Itr-048739	Ictidomys tridecemlineatus	91.04	2.00e-94	337.00
IUUC-Lch-049415	Latimeria chalumnae	70.89	1.00e-57	215.00
IUUC-Lpe-050956	Leersia perrieri	48.30	1.00e-33	136.00
IUUC-Lma-052996	Leptosphaeria maculans	52.29	3.00e-32	132.00
IUUC-Laf-053337	Loxodonta africana	93.56	2.00e-90	325.00
IUUC-Mcc-055485	Macaca mulatta	88.94	4.00e-103	367.00
IUUC-Meu-056123	Macropus eugenii	97.40	5.00e-87	313.00
IUUC-Mtr-058300	Medicago truncatula	57.95	2.00e-56	212.00
IUUC-Mla-059060	Melampsora laricipopulina	50.92	6.00e-50	189.00
IUUC-Mmr-061005	Microcebus murinus	93.53	2.00e-90	324.00
IUUC-Mdo-062979	Monodelphis domestica	97.60	1.00e-69	255.00
IUUC-Mmu-063778	Mus musculus	92.50	2.00e-93	334.00
IUUC-Mac-065490	Musa acuminata	60.82	4.00e-49	188.00
IUUC-Mpu-065829	Mustela putorius furo	96.53	8.00e-101	359.00
IUUC-Mlu-067498	Myotis lucifugus	95.42	1.00e-80	292.00
IUUC-Nfi-068520	Neosartorya fischeri	50.78	6.00e-35	141.00
IUUC-Nle-069727	Nomascus leucogenys	99.50	2.00e-106	377.00
IUUC-Opr-071066	Ochotona princeps	98.23	5.00e-63	231.00
IUUC-Ont-072363	Oreochromis niloticus	70.16	2.00e-75	275.00
IUUC-Oan-073383	Ornithorhynchus anatinus	92.73	3.00e-57	213.00
IUUC-Ocu-074599	Oryctolagus cuniculus	98.50	3.00e-75	273.00
IUUC-Oba-075186	Oryza barthii	60.82	9.00e-52	196.00
IUUC-Obr-076104	Oryza brachyantha	60.82	4.00e-50	191.00
IUUC-Ogl-077835	Oryza glaberrima	60.82	9.00e-52	196.00
IUUC-Ogu-078690	Oryza glumaepatula	60.82	9.00e-52	196.00
IUUC-Oin-080215	Oryza indica	60.82	9.00e-52	196.00
IUUC-Olo-080816	Oryza longistaminata	60.82	9.00e-52	196.00
IUUC-Ome-081657	Oryza meridionalis	60.82	2.00e-51	195.00
IUUC-Oni-082601	Oryza nivara	60.82	9.00e-52	196.00
IUUC-Opu-083367	Oryza punctata	61.40	2.00e-51	195.00
IUUC-Oru-084477	Oryza rufipogon	60.82	8.00e-52	196.00
IUUC-Osa-086119	Oryza sativa	60.82	8.00e-52	196.00
IUUC-Ola-086702	Oryzias latipes	80.25	5.00e-77	280.00
IUUC-Olu-087576	Ostreococcus lucimarinus	54.61	3.00e-47	181.00
IUUC-Oga-088946	Otolemur garnettii	95.52	7.00e-98	349.00
IUUC-Oar-089564	Ovis aries	95.05	6.00e-93	332.00
IUUC-Pan-092382	Papio anubis	88.94	6.00e-103	366.00
IUUC-Psi-093891	Pelodiscus sinensis	89.38	2.00e-60	223.00
IUUC-Pma-094344	Petromyzon marinus	82.35	2.00e-75	274.00
IUUC-Ppa-095452	Physcomitrella patens	55.56	4.00e-48	184.00
IUUC-Pfo-097288	Poecilia formosa	81.10	2.00e-78	285.00
IUUC-Pab-098506	Pongo abelii	100.00	5.00e-107	379.00
IUUC-Pop-098882	Populus trichocarpa	57.39	7.00e-58	216.00
IUUC-Pca-100749	Procavia capensis	92.57	5.00e-92	329.00
IUUC-Ppe-102084	Prunus persica	57.95	1.00e-57	216.00
IUUC-Pva-102755	Pteropus vampyrus	95.54	6.00e-95	339.00
IUUC-Pgr-103394	Puccinia graminis	51.52	2.00e-48	186.00
IUUC-Ptt-103750	Puccinia triticina	54.30	3.00e-48	184.00
IUUC-Pte-104240	Pyrenophora teres	49.23	2.00e-31	130.00
IUUC-Pyt-104483	Pyrenophora triticirepentis	48.46	5.00e-31	128.00
IUUC-Rno-105739	Rattus norvegicus	93.56	4.00e-100	357.00
IUUC-Smo-108939	Selaginella moellendorffii	54.60	1.00e-46	179.00
IUUC-Sit-109881	Setaria italica	60.82	2.00e-50	192.00
IUUC-Sly-111764	Solanum lycopersicum	57.89	1.00e-57	216.00
IUUC-Stu-111968	Solanum tuberosum	57.89	1.00e-57	216.00
IUUC-Sar-113093	Sorex araneus	64.68	6.00e-56	209.00
IUUC-Sbi-113842	Sorghum bicolor	61.40	2.00e-50	191.00
IUUC-Sre-115036	Sporisorium reilianum	43.37	6.00e-34	136.00
IUUC-Tru-117716	Takifugu rubripes	81.71	2.00e-78	284.00
IUUC-Tni-120210	Tetraodon nigroviridis	81.71	1.00e-78	285.00
IUUC-Tca-121315	Theobroma cacao	59.06	4.00e-58	218.00
IUUC-Tae-124474	Triticum aestivum	59.88	4.00e-50	191.00
IUUC-Tur-126669	Triticum urartu	59.65	2.00e-49	189.00
IUUC-Tme-127125	Tuber melanosporum	50.00	1.00e-39	156.00
IUUC-Tbe-128157	Tupaia belangeri	94.61	1.00e-89	321.00
IUUC-Ttr-128593	Tursiops truncatus	94.55	2.00e-99	354.00
IUUC-Uma-129592	Ustilago maydis	48.37	5.00e-41	160.00
IUUC-Vvi-131716	Vitis vinifera	57.95	2.00e-58	218.00
IUUC-Xtr-132592	Xenopus tropicalis	74.00	2.00e-83	301.00
IUUC-Xma-133064	Xiphophorus maculatus	78.44	1.00e-70	259.00
IUUC-Yli-134575	Yarrowia lipolytica	49.31	6.00e-38	150.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence