iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-054121

UUCD1 version

UUC-LoA-01109

Ensembl Protein ID

ENSLAFP00000011749.4

UniProt Accession

G3TCG1; G3TCG1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000014025.4	ENSLAFT00000014029.4	ENSLAFP00000011749.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.70e-68	230.2	416	794

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw......kskkk.............avspr 71
           Gl N gN CY+N++LQ+L+++p++ +l++   +   +  +++ +++++++s+ +l++e++      k ++              a++p+
   Q: 416  GLINKGNWCYINATLQALVACPPMYHLMKF-IPVYSK-AQRPCTSTPMIDSFVRLMNEFTnmpvppKPRQAlgdkivrdirpgaAFEPT 502
           9***************************99.333333.345799***************7666654333337777888888888***** PP
   S: 72   ellkalkkeaeefs.gyeqqDaqEflaflldqleeelkk.................eknkpkeeeeeedkselsde........aeekk 134
            +++ l  +++++s + +q+Da+E+l f+l++l+ee+ +                  k+  ++eee e++ e s++        +    
   Q: 503  YIYRLLTVIKSSLSeKGRQEDAEEYLGFILNGLHEEMLSlkkllspnnekltvsngPKSPLVNEEEREEQGEGSEDeweqvgprN---- 587
           *9999999999966599********************555557777777777666533333333333333333344455555551.... PP
   S: 135  kkknk...........slisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck 212
               k           ++i+ +F+g+++ +++ ++  ++s + +pf++l+l++++++ +   ++qd+Les +++e+++g    y++k +
   Q: 588  ----KtsvtrqadfvqTPITGIFGGHIR-SVVYQQTSKESATLQPFFTLQLDIQSDKIR---TVQDALESLVARESVQG----YTTKTR 664
           ....344444555666***********9.6788999999******************99...****************8....999999 PP
   S: 213  kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke...kkkYeLiavvvHsG.slssGHYva 297
           +++e +++++l+klP+vL+lhLkRf ++++++++ k+ k++e+p  L++s+ + sp  k+k+   +++Y+L+avv+H+G s+ +GHY++
   Q: 665  QEVEISRRVTLEKLPPVLVLHLKRFVYEKTGGCQ-KLIKNIEYPVDLEISKELLSPGVKNKNfkcHRTYRLFAVVYHHGnSATGGHYTT 752
           ***************************9998886.****************999988777777879*********************** PP
   S: 298  yvknekgk.WllfdDskVtevkeeevleetg.staYvlfYkr 337
           +v +   + Wl++dD++V++v++ +v++ t+ +taY+l+Y+r
   Q: 753  DVFQIGLNgWLRIDDQTVKVVTQYQVVRPTAeRTAYLLYYRR 794
           ****87777*****************998889********98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LSYLLQYIFG DFSPDEFNQF FVTPRSSVEL PPYNGTVLCG TQAADELPDG QEYQRIEFGV 60
NEIIEPDDTL LRTPSYSISS TLNPQAPEFI LGCSASKKTP DDLDKEANYS STECQYPGSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTCTTATT TATTACAGTA TATTTTTGGA GATTTTAGCC CTGATGAGTT CAATCAATTC 60
TTTGTGACGC CTCGTTCTTC AGTTGAGGTA AGATTAAACT TTGTTTTAGT GAGTATATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009818--Ataxin-2_C
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF07145--PAM2
PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0004197--F:cysteine-type endopeptidase activity
GO:0003723--F:RNA binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0071347--P:cellular response to interleukin-1
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016579--P:protein deubiquitination
GO:0010506--P:regulation of autophagy
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000082	Aegilops tauschii	29.93	2.00e-44	174.00
IUUC-Aml-001584	Ailuropoda melanoleuca	86.31	0.00e+00	1306.00
IUUC-Atr-002927	Amborella trichopoda	30.09	2.00e-59	223.00
IUUC-Apl-003988	Anas platyrhynchos	78.67	0.00e+00	1185.00
IUUC-Aca-004461	Anolis carolinensis	88.92	9.00e-166	575.00
IUUC-Aly-006038	Arabidopsis lyrata	35.38	2.00e-54	207.00
IUUC-Ath-007328	Arabidopsis thaliana	35.13	3.00e-53	202.00
IUUC-Ago-007717	Ashbya gossypii	29.21	5.00e-43	169.00
IUUC-Acl-008188	Aspergillus clavatus	34.09	5.00e-63	236.00
IUUC-Afl-008456	Aspergillus flavus	37.09	1.00e-47	184.00
IUUC-Afu-009067	Aspergillus fumigatus	35.48	6.00e-64	239.00
IUUC-Ani-009483	Aspergillus nidulans	33.68	3.00e-62	233.00
IUUC-Ang-009639	Aspergillus niger	36.13	2.00e-60	227.00
IUUC-Aor-010040	Aspergillus oryzae	35.90	7.00e-60	225.00
IUUC-Ate-010310	Aspergillus terreus	34.33	6.00e-61	229.00
IUUC-Ame-011012	Astyanax mexicanus	67.01	7.00e-162	564.00
IUUC-Bgr-012311	Blumeria graminis	35.03	3.00e-43	169.00
IUUC-Bta-013299	Bos taurus	85.89	0.00e+00	1257.00
IUUC-Bci-013783	Botrytis cinerea	38.36	2.00e-60	227.00
IUUC-Bdi-015039	Brachypodium distachyon	32.28	3.00e-49	189.00
IUUC-Bol-015806	Brassica oleracea	36.92	2.00e-62	233.00
IUUC-Bra-017076	Brassica rapa	37.18	8.00e-63	234.00
IUUC-Cja-018715	Callithrix jacchus	87.01	0.00e+00	1332.00
IUUC-Cfa-020194	Canis familiaris	87.22	0.00e+00	1341.00
IUUC-Cpo-022272	Cavia porcellus	73.37	0.00e+00	1036.00
IUUC-Cre-022713	Chlamydomonas reinhardtii	34.78	3.00e-34	140.00
IUUC-Csa-023310	Chlorocebus sabaeus	87.89	0.00e+00	1349.00
IUUC-Cho-024966	Choloepus hoffmanni	77.78	0.00e+00	973.00
IUUC-Cin-025616	Ciona intestinalis	42.21	1.00e-106	380.00
IUUC-Csv-026043	Ciona savignyi	46.67	1.00e-98	352.00
IUUC-Cgl-026421	Colletotrichum gloeosporioides	34.05	4.00e-46	179.00
IUUC-Cne-026962	Cryptococcus neoformans	35.05	2.00e-49	191.00
IUUC-Cme-027113	Cyanidioschyzon merolae	30.68	1.00e-38	154.00
IUUC-Dre-028072	Danio rerio	76.99	0.00e+00	710.00
IUUC-Dno-029489	Dasypus novemcinctus	87.59	0.00e+00	1405.00
IUUC-Dor-031068	Dipodomys ordii	72.31	3.00e-137	482.00
IUUC-Dse-031553	Dothistroma septosporum	36.48	6.00e-56	212.00
IUUC-Dme-031759	Drosophila melanogaster	42.07	3.00e-82	300.00
IUUC-Ete-032549	Echinops telfairi	80.75	0.00e+00	925.00
IUUC-Eca-033380	Equus caballus	86.89	0.00e+00	1348.00
IUUC-Eeu-034818	Erinaceus europaeus	83.48	0.00e+00	1258.00
IUUC-Fca-035535	Felis catus	86.10	0.00e+00	1207.00
IUUC-Fal-036627	Ficedula albicollis	76.07	0.00e+00	1118.00
IUUC-Fox-037904	Fusarium oxysporum	36.64	1.00e-52	201.00
IUUC-Fso-038170	Fusarium solani	34.10	2.00e-52	200.00
IUUC-Gmo-039499	Gadus morhua	69.92	0.00e+00	675.00
IUUC-Ggr-040042	Gaeumannomyces graminis	35.28	2.00e-61	231.00
IUUC-Gga-040571	Gallus gallus	78.84	0.00e+00	1173.00
IUUC-Gac-041345	Gasterosteus aculeatus	75.65	0.00e+00	662.00
IUUC-Gma-044407	Glycine max	34.36	3.00e-58	219.00
IUUC-Ggo-044652	Gorilla gorilla	88.27	0.00e+00	1374.00
IUUC-Hsa-045864	Homo sapiens	88.27	0.00e+00	1372.00
IUUC-Hvu-047071	Hordeum vulgare	32.50	8.00e-52	197.00
IUUC-Itr-048216	Ictidomys tridecemlineatus	88.87	0.00e+00	1012.00
IUUC-Kpa-049132	Komagataella pastoris	30.94	4.00e-47	182.00
IUUC-Lch-050040	Latimeria chalumnae	69.97	0.00e+00	939.00
IUUC-Loc-052449	Lepisosteus oculatus	75.05	0.00e+00	710.00
IUUC-Lma-053248	Leptosphaeria maculans	35.48	8.00e-58	218.00
IUUC-Mcc-055514	Macaca mulatta	88.27	0.00e+00	1354.00
IUUC-Meu-056873	Macropus eugenii	73.16	0.00e+00	860.00
IUUC-Mor-057243	Magnaporthe oryzae	33.59	7.00e-58	219.00
IUUC-Mpo-057439	Magnaporthe poae	35.54	5.00e-61	229.00
IUUC-Mtr-058457	Medicago truncatula	34.62	7.00e-58	218.00
IUUC-Mla-058929	Melampsora laricipopulina	31.10	1.00e-55	211.00
IUUC-Mga-060157	Meleagris gallopavo	76.78	0.00e+00	1174.00
IUUC-Mvi-060442	Microbotryum violaceum	33.14	5.00e-56	213.00
IUUC-Mmr-061062	Microcebus murinus	87.63	0.00e+00	1369.00
IUUC-Mdo-062798	Monodelphis domestica	80.15	0.00e+00	1241.00
IUUC-Mmu-064050	Mus musculus	81.08	0.00e+00	1248.00
IUUC-Mac-065619	Musa acuminata	35.04	2.00e-56	212.00
IUUC-Mpu-066554	Mustela putorius furo	85.45	0.00e+00	1286.00
IUUC-Mlu-068003	Myotis lucifugus	86.27	0.00e+00	1323.00
IUUC-Nfi-068612	Neosartorya fischeri	34.74	5.00e-63	236.00
IUUC-Ncr-068878	Neurospora crassa	36.34	1.00e-52	201.00
IUUC-Nle-069661	Nomascus leucogenys	88.27	0.00e+00	1354.00
IUUC-Opr-070944	Ochotona princeps	79.18	4.00e-172	598.00
IUUC-Ont-071266	Oreochromis niloticus	57.41	0.00e+00	797.00
IUUC-Oan-073442	Ornithorhynchus anatinus	80.27	0.00e+00	1168.00
IUUC-Ocu-073788	Oryctolagus cuniculus	79.30	0.00e+00	1131.00
IUUC-Oba-075085	Oryza barthii	33.81	1.00e-37	149.00
IUUC-Obr-076663	Oryza brachyantha	32.65	1.00e-45	177.00
IUUC-Ogl-076937	Oryza glaberrima	30.02	6.00e-49	188.00
IUUC-Ogu-078909	Oryza glumaepatula	30.19	3.00e-47	183.00
IUUC-Oin-079617	Oryza indica	31.25	1.00e-48	187.00
IUUC-Olo-081043	Oryza longistaminata	25.89	5.00e-25	108.00
IUUC-Oni-082914	Oryza nivara	30.19	2.00e-47	183.00
IUUC-Oru-084878	Oryza rufipogon	30.19	2.00e-47	183.00
IUUC-Osa-085822	Oryza sativa	30.82	3.00e-51	196.00
IUUC-Ola-086931	Oryzias latipes	57.36	0.00e+00	795.00
IUUC-Oga-088443	Otolemur garnettii	86.45	0.00e+00	1362.00
IUUC-Oar-089325	Ovis aries	83.04	0.00e+00	1162.00
IUUC-Ptr-091584	Pan troglodytes	85.12	0.00e+00	1277.00
IUUC-Pan-092551	Papio anubis	86.13	0.00e+00	1313.00
IUUC-Psi-093366	Pelodiscus sinensis	74.90	0.00e+00	716.00
IUUC-Pno-095136	Phaeosphaeria nodorum	34.81	1.00e-52	201.00
IUUC-Ppa-095574	Physcomitrella patens	35.54	9.00e-60	224.00
IUUC-Pfo-097462	Poecilia formosa	56.64	0.00e+00	783.00
IUUC-Pab-098547	Pongo abelii	88.27	0.00e+00	1355.00
IUUC-Pop-099529	Populus trichocarpa	37.18	2.00e-62	233.00
IUUC-Pca-101066	Procavia capensis	84.47	0.00e+00	1270.00
IUUC-Ppe-102110	Prunus persica	36.39	9.00e-60	224.00
IUUC-Pva-103015	Pteropus vampyrus	82.24	0.00e+00	1236.00
IUUC-Ptt-103998	Puccinia triticina	33.25	8.00e-53	201.00
IUUC-Pte-104417	Pyrenophora teres	34.34	1.00e-54	208.00
IUUC-Pyt-104820	Pyrenophora triticirepentis	35.10	2.00e-54	207.00
IUUC-Rno-105533	Rattus norvegicus	81.99	0.00e+00	1251.00
IUUC-Sce-106160	Saccharomyces cerevisiae	26.96	1.00e-38	155.00
IUUC-Sha-106590	Sarcophilus harrisii	80.58	0.00e+00	1223.00
IUUC-Sja-107669	Schizosaccharomyces japonicus	34.87	2.00e-55	210.00
IUUC-Spo-108353	Schizosaccharomyces pombe	37.14	3.00e-64	239.00
IUUC-Ssl-108599	Sclerotinia sclerotiorum	37.56	1.00e-58	221.00
IUUC-Smo-108842	Selaginella moellendorffii	37.28	3.00e-37	148.00
IUUC-Sit-110781	Setaria italica	32.20	3.00e-56	213.00
IUUC-Sly-111797	Solanum lycopersicum	34.02	9.00e-56	211.00
IUUC-Stu-112188	Solanum tuberosum	34.95	2.00e-56	213.00
IUUC-Sbi-114862	Sorghum bicolor	32.51	8.00e-46	178.00
IUUC-Sre-115162	Sporisorium reilianum	34.53	3.00e-66	246.00
IUUC-Ssc-115505	Sus scrofa	95.15	1.00e-165	575.00
IUUC-Tgu-116535	Taeniopygia guttata	76.29	0.00e+00	1136.00
IUUC-Tru-117542	Takifugu rubripes	76.56	0.00e+00	704.00
IUUC-Tni-120200	Tetraodon nigroviridis	57.68	0.00e+00	801.00
IUUC-Tca-121548	Theobroma cacao	33.33	3.00e-43	169.00
IUUC-Tre-122124	Trichoderma reesei	37.02	3.00e-60	226.00
IUUC-Tvi-122457	Trichoderma virens	34.58	1.00e-52	201.00
IUUC-Tae-125646	Triticum aestivum	33.16	2.00e-54	207.00
IUUC-Tme-127180	Tuber melanosporum	39.41	2.00e-69	256.00
IUUC-Tbe-127530	Tupaia belangeri	72.90	0.00e+00	1023.00
IUUC-Ttr-128549	Tursiops truncatus	79.45	0.00e+00	1190.00
IUUC-Uma-129381	Ustilago maydis	34.27	3.00e-65	243.00
IUUC-Vda-129889	Verticillium dahliae	32.37	8.00e-52	198.00
IUUC-Vpa-130100	Vicugna pacos	80.73	0.00e+00	1204.00
IUUC-Vvi-131366	Vitis vinifera	36.90	1.00e-64	240.00
IUUC-Xtr-132048	Xenopus tropicalis	63.29	0.00e+00	935.00
IUUC-Xma-133593	Xiphophorus maculatus	57.52	0.00e+00	793.00
IUUC-Yli-134338	Yarrowia lipolytica	30.17	9.00e-33	135.00
IUUC-Zma-135586	Zea mays	31.44	8.00e-49	187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence