iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058248

Ensembl Protein ID

KEH43347

UniProt Accession

A0A072VNH5; A0A072VNH5_MEDTR

Genbank Protein ID

KEH43347.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

CM001217

Gene Name

MTR_1g090827

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_1g090827	KEH43347	KEH43347

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-36	124.0	50	85
UBD/Beta-Prp	1.80e-76	258.7	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           H ++v++++f ++ +l+vsG+dD +ikvW+++ +++
   Q: 50   HDGPVRGVHFhNSqPLFVSGGDDYKIKVWNYKLHRC 85
           99********9777****************876666 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+p++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHPKRPWILASLHSGVIQLWDYRMGTLIDKFDEHDGPVRGVHFHNSQPLFVSGGDDYKIKVWNYKLHRCLFTLLGHLDYIRTVQFHH 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............ktgkllrtl............tgg 178
           ++ ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+ +hp+++l+vs+slD+tvr+Wd+               + g++ ++l            +g 
   Q: 104  ESPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCALFHPKDDLVVSASLDQTVRVWDIgslkrksaspaddilRLGQMNTDLfggvdavvkyvlEG- 202
           **************************.**************************************************56666665566666666666365. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
           h++ v++ sf+++ + +vs+++d++vk+w +  ++   v+tl+gh +nv++v f+ +++++vs s+D+siriWd ++++ ++t+ +++++++  ++ +++ 
   Q: 203  HDRGVNWASFHPTLPLIVSAADDRQVKIWRMNDTKAweVDTLRGHMNNVSCVMFHAKQDIIVSNSEDKSIRIWDATKRTGIQTFRREHDRFWILSA-HPEM 302
           ********************************777668**********************************************************.6666 PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n l++g  ds   ++kl++++p
   Q: 303  NLLAAG-HDSGMIVFKLERERP 323
           655555.689999999988765 PP

Organism

Medicago truncatula

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHPK RPWILASLHS GVIQLWDYRM GTLIDKFDEH DGPVRGVHFH 60
NSQPLFVSGG DDYKIKVWNY KLHRCLFTLL GHLDYIRTVQ FHHESPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAAAAATAA CAGTATAGTA AATCGTATAT GCTCCCGAAG AGGGTTCTCA GAAGGATCTC 60
TCATTCTCAT TCTCATCACT ACTCAGATCT CAATCTCCTT CTCTTTCTTT CTTTATTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

mtr:MTR_1g090827

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	75.63	0.00e+00	1934.00
IUUC-Aml-001758	Ailuropoda melanoleuca	54.95	0.00e+00	1376.00
IUUC-Atr-002493	Amborella trichopoda	79.47	0.00e+00	1964.00
IUUC-Apl-003385	Anas platyrhynchos	50.23	0.00e+00	1048.00
IUUC-Aca-005154	Anolis carolinensis	79.31	4.00e-95	339.00
IUUC-Aly-006020	Arabidopsis lyrata	81.05	0.00e+00	2015.00
IUUC-Ath-007360	Arabidopsis thaliana	81.79	0.00e+00	2027.00
IUUC-Ago-007992	Ashbya gossypii	43.33	0.00e+00	972.00
IUUC-Acl-008027	Aspergillus clavatus	55.38	0.00e+00	969.00
IUUC-Afl-008644	Aspergillus flavus	47.65	0.00e+00	1115.00
IUUC-Afu-008964	Aspergillus fumigatus	48.17	0.00e+00	1135.00
IUUC-Ani-009379	Aspergillus nidulans	54.82	0.00e+00	973.00
IUUC-Ang-009756	Aspergillus niger	47.68	0.00e+00	1131.00
IUUC-Aor-010174	Aspergillus oryzae	47.61	0.00e+00	1116.00
IUUC-Ate-010302	Aspergillus terreus	48.01	0.00e+00	1162.00
IUUC-Ame-011229	Astyanax mexicanus	53.97	0.00e+00	1332.00
IUUC-Bgr-012300	Blumeria graminis	47.02	0.00e+00	1092.00
IUUC-Bta-012524	Bos taurus	55.27	0.00e+00	1367.00
IUUC-Bci-013781	Botrytis cinerea	47.15	0.00e+00	1124.00
IUUC-Bdi-014549	Brachypodium distachyon	76.33	0.00e+00	1969.00
IUUC-Bol-015925	Brassica oleracea	80.69	0.00e+00	1997.00
IUUC-Bra-016978	Brassica rapa	81.08	0.00e+00	2016.00
IUUC-Cel-018115	Caenorhabditis elegans	55.65	0.00e+00	942.00
IUUC-Cja-019107	Callithrix jacchus	54.43	0.00e+00	1357.00
IUUC-Cfa-020675	Canis familiaris	54.46	0.00e+00	1347.00
IUUC-Cpo-021813	Cavia porcellus	55.51	0.00e+00	1387.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	70.31	0.00e+00	1249.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.35	0.00e+00	1387.00
IUUC-Cho-024704	Choloepus hoffmanni	42.78	3.00e-179	622.00
IUUC-Cin-025572	Ciona intestinalis	51.53	0.00e+00	1256.00
IUUC-Csv-025864	Ciona savignyi	58.87	0.00e+00	999.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	47.45	0.00e+00	1119.00
IUUC-Cne-027053	Cryptococcus neoformans	51.41	0.00e+00	1189.00
IUUC-Dre-027421	Danio rerio	54.77	0.00e+00	1356.00
IUUC-Dno-029303	Dasypus novemcinctus	55.51	0.00e+00	1392.00
IUUC-Dor-030290	Dipodomys ordii	53.09	5.00e-163	568.00
IUUC-Dse-031543	Dothistroma septosporum	46.80	0.00e+00	1080.00
IUUC-Dme-031945	Drosophila melanogaster	60.65	0.00e+00	1018.00
IUUC-Ete-032873	Echinops telfairi	52.95	0.00e+00	1207.00
IUUC-Eca-033773	Equus caballus	54.31	0.00e+00	1346.00
IUUC-Eeu-034874	Erinaceus europaeus	42.51	0.00e+00	677.00
IUUC-Fca-035739	Felis catus	54.47	0.00e+00	1337.00
IUUC-Fal-037263	Ficedula albicollis	51.50	0.00e+00	1215.00
IUUC-Fox-037738	Fusarium oxysporum	47.27	0.00e+00	1144.00
IUUC-Fso-038153	Fusarium solani	47.11	0.00e+00	1139.00
IUUC-Gmo-039602	Gadus morhua	51.37	0.00e+00	1239.00
IUUC-Ggr-039931	Gaeumannomyces graminis	53.38	0.00e+00	963.00
IUUC-Gga-040590	Gallus gallus	55.38	0.00e+00	1372.00
IUUC-Gac-041318	Gasterosteus aculeatus	54.35	0.00e+00	1358.00
IUUC-Gma-043894	Glycine max	92.69	0.00e+00	2273.00
IUUC-Ggo-045029	Gorilla gorilla	54.95	0.00e+00	1379.00
IUUC-Hsa-046078	Homo sapiens	55.03	0.00e+00	1381.00
IUUC-Hvu-047556	Hordeum vulgare	75.47	0.00e+00	1975.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	46.84	0.00e+00	782.00
IUUC-Kpa-049256	Komagataella pastoris	45.48	0.00e+00	1055.00
IUUC-Lch-049706	Latimeria chalumnae	55.00	0.00e+00	1362.00
IUUC-Loc-051867	Lepisosteus oculatus	50.35	0.00e+00	813.00
IUUC-Lma-053138	Leptosphaeria maculans	53.34	0.00e+00	984.00
IUUC-Laf-053510	Loxodonta africana	55.96	0.00e+00	1390.00
IUUC-Mcc-055836	Macaca mulatta	54.96	0.00e+00	1378.00
IUUC-Meu-056238	Macropus eugenii	57.04	0.00e+00	764.00
IUUC-Mor-057172	Magnaporthe oryzae	46.47	0.00e+00	1117.00
IUUC-Mpo-057300	Magnaporthe poae	46.53	0.00e+00	1109.00
IUUC-Mla-059019	Melampsora laricipopulina	51.54	0.00e+00	1244.00
IUUC-Mga-059499	Meleagris gallopavo	55.30	0.00e+00	1367.00
IUUC-Mvi-060336	Microbotryum violaceum	50.89	0.00e+00	1224.00
IUUC-Mmr-061102	Microcebus murinus	54.74	0.00e+00	1363.00
IUUC-Mdo-062594	Monodelphis domestica	55.75	0.00e+00	1402.00
IUUC-Mmu-063736	Mus musculus	55.06	0.00e+00	1373.00
IUUC-Mpu-066701	Mustela putorius furo	55.35	0.00e+00	1370.00
IUUC-Mlu-067392	Myotis lucifugus	55.50	0.00e+00	1366.00
IUUC-Nfi-068270	Neosartorya fischeri	55.26	0.00e+00	971.00
IUUC-Ncr-068892	Neurospora crassa	47.85	0.00e+00	1126.00
IUUC-Nle-069634	Nomascus leucogenys	66.42	0.00e+00	939.00
IUUC-Opr-070952	Ochotona princeps	42.12	0.00e+00	677.00
IUUC-Ont-072488	Oreochromis niloticus	54.55	0.00e+00	1350.00
IUUC-Ocu-074211	Oryctolagus cuniculus	55.27	0.00e+00	1381.00
IUUC-Oba-075761	Oryza barthii	76.70	0.00e+00	1936.00
IUUC-Obr-076429	Oryza brachyantha	76.49	0.00e+00	1942.00
IUUC-Ogl-077364	Oryza glaberrima	76.80	0.00e+00	1940.00
IUUC-Ogu-078257	Oryza glumaepatula	76.66	0.00e+00	1880.00
IUUC-Oin-080029	Oryza indica	76.48	0.00e+00	1924.00
IUUC-Ome-081668	Oryza meridionalis	82.15	0.00e+00	1249.00
IUUC-Oni-082608	Oryza nivara	76.56	0.00e+00	1927.00
IUUC-Opu-083697	Oryza punctata	77.13	0.00e+00	1946.00
IUUC-Oru-084274	Oryza rufipogon	76.72	0.00e+00	1937.00
IUUC-Osa-085841	Oryza sativa	76.48	0.00e+00	1928.00
IUUC-Ola-086921	Oryzias latipes	54.18	0.00e+00	1342.00
IUUC-Olu-087639	Ostreococcus lucimarinus	61.75	0.00e+00	1538.00
IUUC-Oga-087991	Otolemur garnettii	52.02	0.00e+00	1276.00
IUUC-Oar-089590	Ovis aries	55.19	0.00e+00	1381.00
IUUC-Ptr-090808	Pan troglodytes	55.03	0.00e+00	1380.00
IUUC-Pan-092475	Papio anubis	55.30	0.00e+00	1381.00
IUUC-Psi-093044	Pelodiscus sinensis	45.80	0.00e+00	953.00
IUUC-Pno-094839	Phaeosphaeria nodorum	45.83	0.00e+00	1061.00
IUUC-Ppa-095254	Physcomitrella patens	68.55	0.00e+00	1763.00
IUUC-Pfo-097493	Poecilia formosa	54.87	0.00e+00	1348.00
IUUC-Pab-098497	Pongo abelii	55.35	0.00e+00	1389.00
IUUC-Pca-100413	Procavia capensis	60.72	0.00e+00	685.00
IUUC-Ppe-101899	Prunus persica	85.89	0.00e+00	2113.00
IUUC-Pva-102126	Pteropus vampyrus	52.61	0.00e+00	1302.00
IUUC-Pgr-103376	Puccinia graminis	51.86	0.00e+00	1248.00
IUUC-Ptt-103978	Puccinia triticina	51.92	0.00e+00	813.00
IUUC-Pte-104126	Pyrenophora teres	53.07	0.00e+00	939.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	44.32	2.00e-175	609.00
IUUC-Rno-105428	Rattus norvegicus	55.47	0.00e+00	1381.00
IUUC-Sce-106464	Saccharomyces cerevisiae	41.70	0.00e+00	942.00
IUUC-Sha-107301	Sarcophilus harrisii	55.16	0.00e+00	1368.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	44.46	0.00e+00	1066.00
IUUC-Spo-108217	Schizosaccharomyces pombe	45.11	0.00e+00	1065.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.19	0.00e+00	1124.00
IUUC-Smo-109582	Selaginella moellendorffii	75.59	0.00e+00	1390.00
IUUC-Sit-109697	Setaria italica	76.17	0.00e+00	1951.00
IUUC-Sly-111759	Solanum lycopersicum	81.71	0.00e+00	2083.00
IUUC-Stu-112564	Solanum tuberosum	81.79	0.00e+00	2082.00
IUUC-Sar-113313	Sorex araneus	42.72	0.00e+00	664.00
IUUC-Sbi-114388	Sorghum bicolor	76.41	0.00e+00	1948.00
IUUC-Sre-115209	Sporisorium reilianum	55.74	0.00e+00	994.00
IUUC-Ssc-115933	Sus scrofa	55.27	0.00e+00	1383.00
IUUC-Tgu-117109	Taeniopygia guttata	44.55	2.00e-111	395.00
IUUC-Tru-117772	Takifugu rubripes	53.89	0.00e+00	1317.00
IUUC-Tsy-119105	Tarsius syrichta	52.78	0.00e+00	1048.00
IUUC-Tni-120556	Tetraodon nigroviridis	42.79	0.00e+00	905.00
IUUC-Tca-121545	Theobroma cacao	84.33	0.00e+00	2120.00
IUUC-Tre-121951	Trichoderma reesei	46.72	0.00e+00	1107.00
IUUC-Tvi-122359	Trichoderma virens	47.29	0.00e+00	1135.00
IUUC-Tae-125527	Triticum aestivum	75.92	0.00e+00	1945.00
IUUC-Tur-126754	Triticum urartu	74.86	0.00e+00	1906.00
IUUC-Tme-127170	Tuber melanosporum	48.33	0.00e+00	1187.00
IUUC-Tbe-127882	Tupaia belangeri	68.93	2.00e-127	449.00
IUUC-Ttr-128217	Tursiops truncatus	53.18	0.00e+00	1313.00
IUUC-Uma-129337	Ustilago maydis	56.21	0.00e+00	994.00
IUUC-Vda-129828	Verticillium dahliae	46.02	0.00e+00	1108.00
IUUC-Vpa-130537	Vicugna pacos	54.58	0.00e+00	1351.00
IUUC-Vvi-130958	Vitis vinifera	83.18	0.00e+00	2086.00
IUUC-Xtr-132857	Xenopus tropicalis	53.31	0.00e+00	1285.00
IUUC-Xma-133138	Xiphophorus maculatus	54.87	0.00e+00	1351.00
IUUC-Yli-134399	Yarrowia lipolytica	49.65	0.00e+00	841.00
IUUC-Zma-135612	Zea mays	76.33	0.00e+00	1955.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence