iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058203

Ensembl Protein ID

KEH23716

UniProt Accession

A0A072U2U4; A0A072U2U4_MEDTR

Genbank Protein ID

KEH23716.1

Protein Name

E3 ubiquitin-protein ligase

Genbank Nucleotide ID

CM001223

Gene Name

MTR_7g094390

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_7g094390	KEH23716	KEH23716

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_PIM	3.60e-16	60.3	402	473

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvk 72
           m + + tl+ k ++l+++++dt++++Keki ++ g+p   q+LI+aGk+L ++ tL +++i+++s++  v++
   Q: 402  MLIYILTLTRKRIPLRIKSSDTIADVKEKILDNEGIPMHMQRLIFAGKELDNSLTLANYHIQEKSTLKFVLR 473
           678999************************************************************988876 PP

Organism

Medicago truncatula

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MGFNRTIPNH HHNIQEESSD NFLRPTTATV TAVPEQTKRI DPNKFEHPNP KGFQKAKQTQ 60
TIRCGGSCES SKNVVTRWRD GQLRKEQHVL ERPSERRGTG GGVEDRCHSR KALNPSVAIF 120

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Nucleotide Sequence
(Fasta)

ATGGGTTTTA ACAGAACAAT ACCCAACCAC CATCACAACA TCCAAGAAGA AAGCAGTGAT 60
AATTTTTTAA GACCAACAAC CGCAACAGTG ACGGCTGTTC CAGAACAAAC AAAAAGAATC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR019956--Ubiquitin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50053--UBIQUITIN_2
PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina
PF00240--ubiquitin

PRINTS

PR00348--UBIQUITIN

SMART

SM00213--UBQ

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_7g094390

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Hvu-047394	Hordeum vulgare	34.62	3.00e-33	134.00
IUUC-Tae-124152	Triticum aestivum	31.73	2.00e-31	129.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence