iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027234

Ensembl Protein ID

CMA138CT

UniProt Accession

M1UN83; M1UN83_CYAM1

Genbank Protein ID

BAM78826.1

Protein Name

Cell cycle switch protein

Genbank Nucleotide ID

AP006483

Gene Name

CYME_CMA138C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMA138C	CMA138CT	CMA138CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	4.50e-129	428.1	139	459
E3 adaptor/Cullin RING/DCX/DWD	1.20e-29	99.1	250	284

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl......eekdlvtsvswie.......egt......llavGtkkgeveiyD 82
           pe++ldape+ dd+ylnLldWs++nvlavaLgs+vylw+a+tg +++l+dl      +++d+v+s++w++       + +      +lavGt++g+v+i+D
   Q: 139  PERILDAPEMVDDYYLNLLDWSANNVLAVALGSAVYLWNASTGGIEQLTDLapgdqhTNQDYVCSLKWVQgsgcaphA-NaeasapYLAVGTAFGHVQIWD 238
           689***********************************************9999877889********9733333331.02333449************** PP
   S: 83   veekkkvrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdassse.Plkkfkehkaav 182
           ve++k++rtl  h+ rvg+L Wn  +l+sGsrd +++++dvr + + +stl ah+qevCGl+w+ ++ +La+GGnDn ++vwd +  + P  +f+eh+aav
   Q: 239  VEANKRLRTLRTHQGRVGSLHWNGPLLCSGSRDSTVQLHDVREARHLASTLVAHEQEVCGLQWSPNGMQLATGGNDNLLMVWDRRALQhPRLRFDEHTAAV 339
           *************************************************************************************9888************ PP
   S: 183  kaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlslalspdgeaiv 283
           ka++w+Pwq+ lLasGGGt+Dr+++fwnt tg +l+++dt+sqvc l ws +++elv++hGf++n++++wkyp l+kvael+gh aRvl+l+ spdg++++
   Q: 340  KALGWCPWQSHLLASGGGTTDRMLRFWNTHTGVCLQAVDTESQVCALQWSMHYRELVTGHGFSRNQLVVWKYPDLNKVAELTGHGARVLHLTTSPDGQTVA 440
           ***************************************************************************************************** PP
   S: 284  taagDetlrfwklfdkkka 302
           +aa+Detlrfwk+f k ++
   Q: 441  SAAADETLRFWKIFPKPQT 459
           **************98776 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           +H+++v +l+++++ll+sGs+D t+++ D+r+ + 
   Q: 250  THQGRVGSLHWNGPLLCSGSRDSTVQLHDVREARH 284
           599********669****************98765 PP

Organism

Cyanidioschyzon merolae

Protein Sequence
(Fasta)

EWQTSDVRSP ARLAAAAEKI HAPGAVDPRQ LAQSLEYRSQ LASELGTAGL LGSVIDSPSD 60
EPWQAHEDTS GLGSRQTAKR GNTAESMPGS GTKILAFKPK PPVHLGDKAA HAAIAVVYTQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGGCAGA CAAGTGACGT GCGCTCGCCA GCGCGTCTGG CTGCAGCCGC AGAGAAGATT 60
CACGCACCTG GAGCAGTCGA CCCTCGACAG CTCGCCCAGA GCCTAGAGTA CCGGAGCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

cme:CYME_CMA138C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000974	Aegilops tauschii	46.58	5.00e-99	352.00
IUUC-Aml-001545	Ailuropoda melanoleuca	52.46	7.00e-103	365.00
IUUC-Atr-003103	Amborella trichopoda	48.64	4.00e-108	382.00
IUUC-Apl-003255	Anas platyrhynchos	50.00	2.00e-103	367.00
IUUC-Aca-004920	Anolis carolinensis	51.16	6.00e-97	345.00
IUUC-Aly-006253	Arabidopsis lyrata	47.63	4.00e-99	352.00
IUUC-Ath-006795	Arabidopsis thaliana	47.63	3.00e-99	352.00
IUUC-Ate-010479	Aspergillus terreus	46.90	2.00e-90	324.00
IUUC-Bgr-012059	Blumeria graminis	45.01	4.00e-97	346.00
IUUC-Bta-012625	Bos taurus	52.73	2.00e-103	366.00
IUUC-Bci-013607	Botrytis cinerea	46.87	3.00e-97	346.00
IUUC-Bdi-014569	Brachypodium distachyon	48.75	4.00e-92	329.00
IUUC-Bol-015368	Brassica oleracea	48.13	1.00e-100	359.00
IUUC-Bra-016738	Brassica rapa	48.72	6.00e-100	355.00
IUUC-Cja-019132	Callithrix jacchus	52.46	3.00e-103	366.00
IUUC-Cfa-020780	Canis familiaris	51.91	9.00e-102	361.00
IUUC-Cpo-022223	Cavia porcellus	52.46	5.00e-95	339.00
IUUC-Cre-022701	Chlamydomonas reinhardtii	51.05	6.00e-106	375.00
IUUC-Csa-023666	Chlorocebus sabaeus	52.19	1.00e-102	364.00
IUUC-Cho-024920	Choloepus hoffmanni	68.47	5.00e-46	176.00
IUUC-Cin-025675	Ciona intestinalis	48.09	3.00e-98	350.00
IUUC-Csv-026019	Ciona savignyi	42.48	7.00e-89	318.00
IUUC-Cgl-026465	Colletotrichum gloeosporioides	45.65	4.00e-94	336.00
IUUC-Dre-028026	Danio rerio	45.11	2.00e-92	330.00
IUUC-Dno-028865	Dasypus novemcinctus	51.77	6.00e-101	358.00
IUUC-Dor-030958	Dipodomys ordii	52.19	2.00e-98	350.00
IUUC-Dse-031391	Dothistroma septosporum	47.41	1.00e-97	348.00
IUUC-Dme-031905	Drosophila melanogaster	46.87	4.00e-104	369.00
IUUC-Ete-032387	Echinops telfairi	47.54	6.00e-92	328.00
IUUC-Eeu-035059	Erinaceus europaeus	59.83	8.00e-80	288.00
IUUC-Fca-036346	Felis catus	50.00	4.00e-89	319.00
IUUC-Fal-037558	Ficedula albicollis	48.92	3.00e-101	359.00
IUUC-Fox-037850	Fusarium oxysporum	46.17	8.00e-94	335.00
IUUC-Fso-038375	Fusarium solani	46.17	2.00e-94	337.00
IUUC-Gmo-039284	Gadus morhua	47.28	2.00e-94	337.00
IUUC-Ggr-039864	Gaeumannomyces graminis	45.14	4.00e-95	339.00
IUUC-Gga-040790	Gallus gallus	51.90	1.00e-105	374.00
IUUC-Gac-041431	Gasterosteus aculeatus	45.65	2.00e-93	333.00
IUUC-Gma-043489	Glycine max	46.88	3.00e-102	362.00
IUUC-Ggo-045052	Gorilla gorilla	51.91	2.00e-102	363.00
IUUC-Hsa-046305	Homo sapiens	51.91	2.00e-102	363.00
IUUC-Hvu-047565	Hordeum vulgare	46.58	5.00e-99	352.00
IUUC-Itr-048461	Ictidomys tridecemlineatus	52.46	6.00e-95	338.00
IUUC-Lpe-050954	Leersia perrieri	48.03	2.00e-93	333.00
IUUC-Loc-052638	Lepisosteus oculatus	47.09	3.00e-90	323.00
IUUC-Lma-052998	Leptosphaeria maculans	47.03	6.00e-98	349.00
IUUC-Laf-053742	Loxodonta africana	52.19	7.00e-102	362.00
IUUC-Mcc-054948	Macaca mulatta	52.19	1.00e-102	364.00
IUUC-Mor-057277	Magnaporthe oryzae	45.36	6.00e-92	328.00
IUUC-Mpo-057624	Magnaporthe poae	45.63	1.00e-92	331.00
IUUC-Mtr-057725	Medicago truncatula	44.85	1.00e-91	327.00
IUUC-Mga-060102	Meleagris gallopavo	51.63	2.00e-105	373.00
IUUC-Mmr-061615	Microcebus murinus	52.19	3.00e-103	366.00
IUUC-Mmu-063864	Mus musculus	51.91	4.00e-98	349.00
IUUC-Mac-064861	Musa acuminata	47.07	3.00e-100	356.00
IUUC-Mpu-066502	Mustela putorius furo	51.91	7.00e-106	375.00
IUUC-Mlu-067277	Myotis lucifugus	53.91	1.00e-101	361.00
IUUC-Ncr-068951	Neurospora crassa	45.45	3.00e-93	333.00
IUUC-Nle-070149	Nomascus leucogenys	51.91	9.00e-101	358.00
IUUC-Ont-071660	Oreochromis niloticus	50.00	2.00e-95	340.00
IUUC-Oan-073677	Ornithorhynchus anatinus	51.60	3.00e-102	363.00
IUUC-Ocu-073797	Oryctolagus cuniculus	52.73	1.00e-103	367.00
IUUC-Oba-075514	Oryza barthii	46.83	2.00e-92	330.00
IUUC-Obr-076018	Oryza brachyantha	46.14	2.00e-100	357.00
IUUC-Ogl-077254	Oryza glaberrima	47.07	4.00e-93	332.00
IUUC-Ogu-078562	Oryza glumaepatula	47.32	1.00e-92	330.00
IUUC-Oin-080094	Oryza indica	47.07	4.00e-93	332.00
IUUC-Olo-080449	Oryza longistaminata	47.46	9.00e-94	334.00
IUUC-Ome-081186	Oryza meridionalis	45.65	8.00e-100	356.00
IUUC-Oni-082243	Oryza nivara	47.07	4.00e-93	332.00
IUUC-Opu-084007	Oryza punctata	47.07	7.00e-92	328.00
IUUC-Oru-084357	Oryza rufipogon	47.56	8.00e-93	331.00
IUUC-Osa-086094	Oryza sativa	47.07	4.00e-93	332.00
IUUC-Ola-086907	Oryzias latipes	48.64	2.00e-93	333.00
IUUC-Olu-087647	Ostreococcus lucimarinus	55.86	2.00e-117	413.00
IUUC-Oga-088184	Otolemur garnettii	50.68	5.00e-99	352.00
IUUC-Oar-090023	Ovis aries	52.59	2.00e-99	353.00
IUUC-Ptr-090935	Pan troglodytes	51.91	2.00e-102	363.00
IUUC-Pan-091845	Papio anubis	52.19	1.00e-102	364.00
IUUC-Psi-093188	Pelodiscus sinensis	50.95	3.00e-105	372.00
IUUC-Pma-094187	Petromyzon marinus	47.95	6.00e-96	342.00
IUUC-Pno-094809	Phaeosphaeria nodorum	45.61	9.00e-100	355.00
IUUC-Ppa-095687	Physcomitrella patens	45.34	3.00e-113	399.00
IUUC-Pab-098603	Pongo abelii	52.19	1.00e-102	364.00
IUUC-Pop-099234	Populus trichocarpa	50.66	1.00e-101	360.00
IUUC-Pca-101062	Procavia capensis	51.51	1.00e-100	357.00
IUUC-Ppe-101865	Prunus persica	48.98	6.00e-91	325.00
IUUC-Pva-102925	Pteropus vampyrus	52.73	2.00e-103	367.00
IUUC-Pte-104142	Pyrenophora teres	45.09	7.00e-99	352.00
IUUC-Pyt-104693	Pyrenophora triticirepentis	45.09	9.00e-99	352.00
IUUC-Rno-106005	Rattus norvegicus	51.91	2.00e-98	350.00
IUUC-Sha-107472	Sarcophilus harrisii	53.01	3.00e-102	362.00
IUUC-Sja-107919	Schizosaccharomyces japonicus	43.92	4.00e-90	322.00
IUUC-Ssl-108507	Sclerotinia sclerotiorum	46.85	2.00e-96	344.00
IUUC-Smo-108922	Selaginella moellendorffii	54.61	1.00e-118	417.00
IUUC-Sit-110032	Setaria italica	48.64	4.00e-104	369.00
IUUC-Sly-111025	Solanum lycopersicum	45.23	2.00e-91	327.00
IUUC-Stu-112676	Solanum tuberosum	45.68	5.00e-94	335.00
IUUC-Sar-113092	Sorex araneus	55.38	5.00e-92	329.00
IUUC-Sbi-114207	Sorghum bicolor	49.61	1.00e-103	367.00
IUUC-Ssc-115710	Sus scrofa	52.73	6.00e-103	365.00
IUUC-Tgu-117100	Taeniopygia guttata	49.60	3.00e-102	363.00
IUUC-Tsy-118931	Tarsius syrichta	41.49	9.00e-63	231.00
IUUC-Tni-120474	Tetraodon nigroviridis	44.82	1.00e-91	327.00
IUUC-Tca-121337	Theobroma cacao	44.62	1.00e-101	360.00
IUUC-Tre-122211	Trichoderma reesei	46.17	1.00e-95	340.00
IUUC-Tvi-122531	Trichoderma virens	46.07	7.00e-94	335.00
IUUC-Tae-123918	Triticum aestivum	46.84	6.00e-100	355.00
IUUC-Tur-126193	Triticum urartu	46.33	1.00e-98	351.00
IUUC-Tme-126905	Tuber melanosporum	47.12	4.00e-98	349.00
IUUC-Tbe-127384	Tupaia belangeri	52.09	5.00e-91	325.00
IUUC-Ttr-128511	Tursiops truncatus	52.46	9.00e-103	364.00
IUUC-Vda-129993	Verticillium dahliae	45.33	2.00e-93	333.00
IUUC-Vpa-130775	Vicugna pacos	41.19	2.00e-60	224.00
IUUC-Vvi-131245	Vitis vinifera	46.19	2.00e-90	323.00
IUUC-Xtr-131993	Xenopus tropicalis	50.86	5.00e-101	359.00
IUUC-Xma-133332	Xiphophorus maculatus	49.18	4.00e-96	342.00
IUUC-Yli-134501	Yarrowia lipolytica	44.53	2.00e-95	340.00
IUUC-Zma-135456	Zea mays	46.49	2.00e-104	370.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence