iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sbi-114528

Ensembl Protein ID

Sb02g011930.1

UniProt Accession

C5X5X4; C5X5X4_SORBI

Genbank Protein ID

EER96354.1

Protein Name

Protein HIRA

Genbank Nucleotide ID

CM000761

Gene Name

SORBI_002G134200

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Sb02g011930	Sb02g011930.1	Sb02g011930.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.90e-22	78.6	123	160
UBD/Beta-Prp	3.30e-40	138.9	16	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+ti++W+++ g ++
   Q: 123  GHTADVVDLNWsPDdSTLASGSLDNTIHIWNMTNGMCT 160
           8***********77799****************99986 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw.................d 80
           + ++++ p++  +atg+ d+++++w++++ ++           l+++ +h + v++v++ ++g +l++gs+D++i +                  d
   Q: 16   MFSIDIQPGGLRFATGGGDQKVRIWSMKSVDKnntdndssqglLATMCDHFGSVNCVRWARHGRYLASGSDDQVILIHerkagsgrsefgsgeppD 111
           5578899999******************9999999*******************************************888888888888888888 PP
   S: 81   lstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +++ k ++tl+gh+++v++l++sp++++l+sGs d+ti++w++ +g c   +l+gh+++v +v+++p g+ ++s s+D+tv +W+ +  +l ++ +
   Q: 112  VENWKVIMTLRGHTADVVDLNWSPDDSTLASGSLDNTIHIWNMTNGMCTA-VLRGHSSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWSLAHKAE 206
           88************************************************.**********************************97666666666 PP
   S: 177  ggh 179
           g h
   Q: 207  G-H 208
           5.3 PP

Organism

Sorghum bicolor

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MIAEKPSWIR HEGLQMFSID IQPGGLRFAT GGGDQKVRIW SMKSVDKNNT DNDSSQGLLA 60
TMCDHFGSVN CVRWARHGRY LASGSDDQVI LIHERKAGSG RSEFGSGEPP DVENWKVIMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAACACGTT CGTCCCATCG TCGTGTTCTT CGCGCCGCCG CCGCCGCCGC CGCCGCCGCC 60
GCCGCCGAGC CGATCGAATC CGCCCGCCGC CGCCGCCGAG TAACCTCCGG ATCCCTACTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0000790--C:nuclear chromatin
GO:0031491--F:nucleosome binding
GO:0003714--F:transcription corepressor activity
GO:0016569--P:covalent chromatin modification
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0031935--P:regulation of chromatin silencing
GO:0006351--P:transcription, DNA-templated

KEGG

sbi:SORBI_02g011930

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001039	Aegilops tauschii	80.32	0.00e+00	1618.00
IUUC-Ago-007766	Ashbya gossypii	32.24	3.00e-64	239.00
IUUC-Afu-008781	Aspergillus fumigatus	32.60	5.00e-66	245.00
IUUC-Ang-009655	Aspergillus niger	35.43	1.00e-69	257.00
IUUC-Aor-010119	Aspergillus oryzae	33.02	9.00e-68	251.00
IUUC-Ate-010530	Aspergillus terreus	28.43	2.00e-57	217.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.29	2.00e-73	270.00
IUUC-Dor-030687	Dipodomys ordii	35.97	1.00e-65	244.00
IUUC-Dse-031334	Dothistroma septosporum	27.81	3.00e-83	302.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.65	1.00e-69	257.00
IUUC-Hvu-047587	Hordeum vulgare	84.75	0.00e+00	1563.00
IUUC-Kpa-049145	Komagataella pastoris	31.94	8.00e-58	218.00
IUUC-Lma-053237	Leptosphaeria maculans	33.49	9.00e-68	251.00
IUUC-Mpo-057364	Magnaporthe poae	34.42	1.00e-69	257.00
IUUC-Nfi-068396	Neosartorya fischeri	32.67	2.00e-65	243.00
IUUC-Opr-070808	Ochotona princeps	41.83	5.00e-55	208.00
IUUC-Opu-084008	Oryza punctata	87.66	0.00e+00	828.00
IUUC-Ola-087302	Oryzias latipes	34.25	2.00e-80	293.00
IUUC-Olu-087611	Ostreococcus lucimarinus	34.79	1.00e-154	540.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.24	5.00e-60	225.00
IUUC-Pgr-103660	Puccinia graminis	35.95	2.00e-60	226.00
IUUC-Ptt-103900	Puccinia triticina	35.68	2.00e-60	226.00
IUUC-Pte-104209	Pyrenophora teres	33.88	2.00e-72	266.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	33.88	2.00e-71	263.00
IUUC-Sce-106291	Saccharomyces cerevisiae	33.56	9.00e-64	237.00
IUUC-Sja-107833	Schizosaccharomyces japonicus	28.85	1.00e-89	323.00
IUUC-Spo-108162	Schizosaccharomyces pombe	34.34	5.00e-76	278.00
IUUC-Smo-109186	Selaginella moellendorffii	51.55	0.00e+00	905.00
IUUC-Sre-115061	Sporisorium reilianum	33.20	3.00e-70	259.00
IUUC-Tre-121887	Trichoderma reesei	32.85	3.00e-64	239.00
IUUC-Tvi-122262	Trichoderma virens	34.67	4.00e-63	236.00
IUUC-Tae-123009	Triticum aestivum	67.30	0.00e+00	1092.00
IUUC-Tme-127202	Tuber melanosporum	29.40	2.00e-53	203.00
IUUC-Tbe-127350	Tupaia belangeri	38.19	2.00e-49	190.00
IUUC-Yli-134424	Yarrowia lipolytica	36.02	3.00e-68	253.00
IUUC-Zma-135839	Zea mays	92.47	0.00e+00	1816.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence