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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045791
Ensembl Protein ID ENSP00000219611.2
UniProt Accession O75808; B1B1M4; Q2KHS2; Q8WTY9; Q9BUW0; CAN15_HUMAN
Genbank Protein ID AAC33822.1; AAK61233.1; CAC14067.1; EAW85803.1; AAH01869.1; AAH21854.1; AAI12919.1
Protein Name Calpain-15; Small optic lobes homolog
Genbank Nucleotide ID U85647; AE006464; Z97986; CH471112; BC001869; BC021854; BC112918
Gene Name CAPN15; SOLH
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000103326.11 ENST00000568988.5 ENSP00000457030.1
ENSG00000103326.11 ENST00000219611.6 ENSP00000219611.2
ENSG00000103326.11 ENST00000637507.1 ENSP00000490480.1
ENSG00000103326.11 ENST00000566977.1 ENSP00000457306.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbCircNetmiRTarBasemicroRNA
TRANSFACTargetScanRepTarSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDPINAHINTInWeb_IM
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDUniProtBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/ZnF/NZF 6.70e-20 71.9 5 31
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/ZnF/NZF
   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
           ++W+C  CTflN +    C++C+ pR+
   Q: 5    GEWSCVRCTFLNPAGQRQCSICEAPRH 31
           79************************8 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MATVGEWSCV RCTFLNPAGQ RQCSICEAPR HKPDLNHILR LSVEEQKWPC ARCTFRNFLG 60
KEACEVCGFT PEPAPGAAFL PVLNGVLPKP PAILGEPKGS CQEEAGPVRT AGLVATEPAR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045791|UBD,NZF|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCGGGCGCGC GATTCACAGC GCCGCGTGCG CCCCGGGCGC GCCGTAGCCG CGGGGCCCGG 60
GCCGGGCGCT ACGCTACGAA GGCAGCGTAA GGCGGGCGCC GGACGCGGGC AGGGGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045791|UBD,NZF|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0677--Repeat
KW-0788--Thiol protease
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR022684--Calpain_cysteine_protease
IPR000169--Pept_cys_AS
IPR001300--Peptidase_C2_calpain_cat
IPR001876--Znf_RanBP2
PROSITE

PS50203--CALPAIN_CAT
PS00139--THIOL_PROTEASE_CYS
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
Pfam

PF00648--Peptidase_C2
PF00641--zf-RanBP
PRINTS

PR00704--CALPAIN
SMART

SM00230--CysPc
SM00547--ZnF_RBZ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0004198--F:calcium-dependent cysteine-type endopeptidase activity
GO:0008234--F:cysteine-type peptidase activity
GO:0008233--F:peptidase activity
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008270--F:zinc ion binding
KEGG hsa:6650
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001505 Ailuropoda melanoleuca 86.00 0.00e+00 1640.00
IUUC-Apl-003593 Anas platyrhynchos 76.57 0.00e+00 1177.00
IUUC-Aca-005082 Anolis carolinensis 72.78 0.00e+00 1592.00
IUUC-Aly-006462 Arabidopsis lyrata 33.87 2.00e-05 43.90
IUUC-Ath-007657 Arabidopsis thaliana 33.87 2.00e-05 43.90
IUUC-Bta-013065 Bos taurus 84.21 0.00e+00 1669.00
IUUC-Bci-013702 Botrytis cinerea 24.65 2.00e-04 40.00
IUUC-Bol-016604 Brassica oleracea 40.98 2.00e-05 43.50
IUUC-Bra-017928 Brassica rapa 33.87 2.00e-05 43.50
IUUC-Cja-019708 Callithrix jacchus 93.91 0.00e+00 1595.00
IUUC-Cfa-020860 Canis familiaris 84.39 0.00e+00 1655.00
IUUC-Cpo-022525 Cavia porcellus 87.30 0.00e+00 1757.00
IUUC-Csa-023316 Chlorocebus sabaeus 97.34 0.00e+00 1570.00
IUUC-Dre-028676 Danio rerio 77.72 0.00e+00 1221.00
IUUC-Dno-029448 Dasypus novemcinctus 83.07 0.00e+00 744.00
IUUC-Dor-030214 Dipodomys ordii 82.90 0.00e+00 1513.00
IUUC-Dme-032148 Drosophila melanogaster 54.59 0.00e+00 710.00
IUUC-Eca-033450 Equus caballus 82.96 0.00e+00 1348.00
IUUC-Eeu-034986 Erinaceus europaeus 88.16 2.00e-133 470.00
IUUC-Fca-036018 Felis catus 82.00 0.00e+00 1299.00
IUUC-Fal-037308 Ficedula albicollis 73.66 0.00e+00 1597.00
IUUC-Gga-041032 Gallus gallus 74.37 0.00e+00 1613.00
IUUC-Ggo-045635 Gorilla gorilla 98.43 0.00e+00 1927.00
IUUC-Hvu-047244 Hordeum vulgare 32.81 7.00e-05 42.40
IUUC-Itr-048401 Ictidomys tridecemlineatus 87.72 0.00e+00 1778.00
IUUC-Lch-050282 Latimeria chalumnae 66.10 0.00e+00 1347.00
IUUC-Loc-052478 Lepisosteus oculatus 72.24 0.00e+00 1159.00
IUUC-Lma-053304 Leptosphaeria maculans 28.68 3.00e-03 36.60
IUUC-Laf-054556 Loxodonta africana 88.13 0.00e+00 1066.00
IUUC-Mcc-054669 Macaca mulatta 97.24 0.00e+00 1813.00
IUUC-Meu-056257 Macropus eugenii 72.24 0.00e+00 832.00
IUUC-Mga-059232 Meleagris gallopavo 73.15 0.00e+00 1578.00
IUUC-Mmr-061524 Microcebus murinus 86.07 0.00e+00 1616.00
IUUC-Mdo-062883 Monodelphis domestica 77.18 0.00e+00 1677.00
IUUC-Mmu-064018 Mus musculus 83.44 0.00e+00 1700.00
IUUC-Mpu-066215 Mustela putorius furo 83.95 0.00e+00 1640.00
IUUC-Mlu-067181 Myotis lucifugus 83.45 0.00e+00 1657.00
IUUC-Opr-070414 Ochotona princeps 84.40 0.00e+00 1694.00
IUUC-Ont-072063 Oreochromis niloticus 72.59 0.00e+00 1209.00
IUUC-Oan-073086 Ornithorhynchus anatinus 71.18 0.00e+00 1152.00
IUUC-Ocu-074037 Oryctolagus cuniculus 82.95 0.00e+00 1518.00
IUUC-Ola-086498 Oryzias latipes 78.04 0.00e+00 1239.00
IUUC-Oga-088087 Otolemur garnettii 86.81 0.00e+00 1789.00
IUUC-Pan-092918 Papio anubis 96.64 0.00e+00 1549.00
IUUC-Pma-094435 Petromyzon marinus 58.18 0.00e+00 868.00
IUUC-Ppa-095919 Physcomitrella patens 36.07 4.00e-04 40.00
IUUC-Pfo-096574 Poecilia formosa 69.68 0.00e+00 1306.00
IUUC-Pab-098098 Pongo abelii 97.15 0.00e+00 979.00
IUUC-Pca-100428 Procavia capensis 79.52 0.00e+00 1429.00
IUUC-Pte-104280 Pyrenophora teres 29.60 4.00e-05 43.10
IUUC-Rno-105671 Rattus norvegicus 83.97 0.00e+00 1722.00
IUUC-Sha-106877 Sarcophilus harrisii 73.44 0.00e+00 1543.00
IUUC-Ssl-108588 Sclerotinia sclerotiorum 24.24 7.00e-03 35.40
IUUC-Ssc-115957 Sus scrofa 82.23 0.00e+00 1587.00
IUUC-Tgu-116764 Taeniopygia guttata 74.41 0.00e+00 1578.00
IUUC-Tru-118000 Takifugu rubripes 77.75 0.00e+00 1228.00
IUUC-Tni-119762 Tetraodon nigroviridis 70.81 0.00e+00 951.00
IUUC-Tme-127206 Tuber melanosporum 63.64 6.00e-04 39.30
IUUC-Ttr-128978 Tursiops truncatus 85.62 0.00e+00 1709.00
IUUC-Vda-130005 Verticillium dahliae 36.54 2.90e-02 33.10
IUUC-Xtr-132023 Xenopus tropicalis 64.14 0.00e+00 1246.00
Created Date 25-Jun-2017

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