iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aor-010111

Ensembl Protein ID

BAE57240

UniProt Accession

Q2UMH5; Q2UMH5_ASPOR

Genbank Protein ID

BAE57240.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

AP007154

Gene Name

AO090001000752

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AO090001000752	BAE57240	BAE57240

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-53	181.0	303	782
UBD/Alpha-Helix/UBA	1.10e-17	62.9	650	688

Active Site

Position(s)	Description	Evidence
312	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
737	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel...................wkskkkavsprellkalkkeae 82
           tGl NlgN+CY+ Sv+QcL+ +pe+++ + + ++e+ + +  ++p ++l ++l+kl   +                      ++k   p ++++ +++ +e
   Q: 303  TGLANLGNSCYLSSVIQCLFDLPEFQQRYRH-ENEEPPLT--DSPAEDLETQLRKLADGIlsgrysradmdvivapdspEVPRQKGLVPAMFKHLVGRGHE 400
           7*****************************9.66665655..57999999*******9996666666666665544433366777**************** PP
   S: 83   efsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetk 183
           efs+++qqDa Efl +l++ ++ +                            +  n s  ++ F + ++++++c  c++v  + ++   +s+pvp ++   
   Q: 401  EFSTMKQQDAFEFLLHLFKLINLSR---------------------------HPDNLSSPTHSFMFAMEQRLQCVCCKKVRYKVDEQDNVSIPVPARRLAL 474
           *******************998777...........................6788999999*********************************999776 PP
   S: 184  ke...........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekq 272
           +            +l dcL++ t+ee ++    + c++c +k   +k+ ++++lP+ L+++  Rf  +  +++++k++  v++ +e Ldlsp+++s +++ 
   Q: 475  PDdttstgqfapvTLFDCLDASTSEEVVD----LVCPSCGSKDGFSKRSSFRTLPQQLVINARRF--ELINWVPTKLDIPVDVSEEpLDLSPYLSSGQKEG 569
           6699999*********************9....9*******************************..6677*************************44444 PP
   S: 273  ke................................................................................................... 274
           +e                                                                                                   
   Q: 570  EEllpdidaskrdfvpnqyaldqllsmgfprarsekalyttgnsdfeaamnwlfahledpdidepltiseirgggtdashdpakvaqlvemgidesrakra 670
           44666666666666666666666666666666666666666666667777777777777777777777777777777777777777777777777777777 PP
   S: 275  ..............................................kkkYeLiavvvHsG.slssGHYvayvkn.....ekgkWllfdDskVtevkeeevl 323
                                                         + +Y+L ++v+H+G s++ GHYva+v++     ++ +W+ f+D+kV +    ++ 
   Q: 671  lgatggdvnraidwvfshpeadaegygresnthsdgcprnlgssdvPARYKLRSIVCHKGsSVHAGHYVAFVRKtlpgqNEPCWVMFNDEKVVKA--GDIH 769
           8888888888888888888888888888888888899999999999****************************887655556********9888..4555 PP
   S: 324  eetgstaYvlfYkr 337
           e++ + aY++f+ r
   Q: 770  EMK-KYAYLYFFSR 782
           533.6******987 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraannnleaAveyLldg 41
           d  k++qlveMG+d+++a++aL a+++++++A+++++++
   Q: 650  DPAKVAQLVEMGIDESRAKRALGATGGDVNRAIDWVFSH 688
           6679*********************************97 PP

Organism

Aspergillus oryzae

Protein Sequence
(Fasta)

MASCVHVNSH DLKPPSLSQA VYREDCTQCF DSIDDEAGLN VCLTCFNGGC AGDRDHASLH 60
FKRHGHPLAL NIKRIRKKVQ RDEPPHKISK LAIAAETDEN RYDTTTRVIC YSCGKDEIDK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCTT GCGTGCATGT AAATTCTCAC GGTTGGTTGG CTGCTAACAA CAATACTCAT 60
GGTGATAGTC TTCGTTAATA TTTCTGTGGC AGATCTAAAG CCCCCATCTC TCTCACAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

aor:AOR_1_1354164

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	31.89	1.00e-98	352.00
IUUC-Aml-002104	Ailuropoda melanoleuca	33.45	3.00e-123	434.00
IUUC-Atr-002580	Amborella trichopoda	33.49	4.00e-111	394.00
IUUC-Apl-003774	Anas platyrhynchos	34.45	2.00e-124	437.00
IUUC-Aca-005368	Anolis carolinensis	33.89	1.00e-127	448.00
IUUC-Aly-005727	Arabidopsis lyrata	34.44	6.00e-118	416.00
IUUC-Ath-006974	Arabidopsis thaliana	34.65	2.00e-119	421.00
IUUC-Ago-007890	Ashbya gossypii	32.73	9.00e-109	385.00
IUUC-Acl-008057	Aspergillus clavatus	73.17	0.00e+00	1164.00
IUUC-Afl-008547	Aspergillus flavus	100.00	0.00e+00	1371.00
IUUC-Afu-008805	Aspergillus fumigatus	67.26	0.00e+00	1028.00
IUUC-Ani-009441	Aspergillus nidulans	63.62	0.00e+00	900.00
IUUC-Ang-009720	Aspergillus niger	71.39	0.00e+00	1137.00
IUUC-Ate-010531	Aspergillus terreus	66.50	0.00e+00	1064.00
IUUC-Ame-011893	Astyanax mexicanus	34.23	7.00e-104	369.00
IUUC-Bgr-012183	Blumeria graminis	54.50	0.00e+00	877.00
IUUC-Bta-013179	Bos taurus	33.29	6.00e-122	429.00
IUUC-Bci-013858	Botrytis cinerea	58.85	0.00e+00	971.00
IUUC-Bdi-014904	Brachypodium distachyon	34.11	3.00e-103	367.00
IUUC-Bol-015536	Brassica oleracea	35.19	8.00e-119	419.00
IUUC-Bra-017939	Brassica rapa	35.24	1.00e-120	425.00
IUUC-Cel-018625	Caenorhabditis elegans	30.10	2.00e-85	308.00
IUUC-Cja-019063	Callithrix jacchus	33.29	3.00e-120	424.00
IUUC-Cfa-020976	Canis familiaris	34.16	2.00e-127	447.00
IUUC-Cpo-022265	Cavia porcellus	33.89	2.00e-126	444.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	33.73	8.00e-65	239.00
IUUC-Csa-024177	Chlorocebus sabaeus	34.55	6.00e-114	403.00
IUUC-Cho-024702	Choloepus hoffmanni	32.47	1.00e-75	275.00
IUUC-Cin-025411	Ciona intestinalis	32.97	6.00e-104	370.00
IUUC-Csv-026347	Ciona savignyi	31.20	4.00e-99	353.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	58.23	0.00e+00	885.00
IUUC-Cne-026831	Cryptococcus neoformans	45.78	0.00e+00	626.00
IUUC-Cme-027335	Cyanidioschyzon merolae	41.26	2.00e-54	206.00
IUUC-Dre-027982	Danio rerio	32.91	3.00e-103	367.00
IUUC-Dno-029034	Dasypus novemcinctus	34.34	1.00e-125	442.00
IUUC-Dor-030479	Dipodomys ordii	34.95	6.00e-57	213.00
IUUC-Dse-031467	Dothistroma septosporum	52.85	0.00e+00	843.00
IUUC-Dme-032075	Drosophila melanogaster	34.50	2.00e-116	411.00
IUUC-Ete-032865	Echinops telfairi	30.42	6.00e-102	363.00
IUUC-Eca-034059	Equus caballus	33.41	2.00e-122	431.00
IUUC-Eeu-035304	Erinaceus europaeus	34.01	1.00e-113	402.00
IUUC-Fca-035515	Felis catus	33.53	2.00e-124	437.00
IUUC-Fal-037271	Ficedula albicollis	35.72	5.00e-123	433.00
IUUC-Fox-037745	Fusarium oxysporum	58.82	0.00e+00	944.00
IUUC-Fso-038158	Fusarium solani	59.24	0.00e+00	933.00
IUUC-Gmo-039071	Gadus morhua	32.62	8.00e-109	386.00
IUUC-Ggr-040098	Gaeumannomyces graminis	57.81	0.00e+00	895.00
IUUC-Gga-040635	Gallus gallus	33.88	1.00e-127	449.00
IUUC-Gac-042528	Gasterosteus aculeatus	34.54	5.00e-113	400.00
IUUC-Gma-042656	Glycine max	32.97	2.00e-112	397.00
IUUC-Ggo-044602	Gorilla gorilla	33.76	4.00e-124	437.00
IUUC-Hsa-045959	Homo sapiens	33.76	4.00e-124	437.00
IUUC-Hvu-047563	Hordeum vulgare	36.53	8.00e-100	355.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	33.72	3.00e-124	437.00
IUUC-Kpa-049156	Komagataella pastoris	40.12	4.00e-168	583.00
IUUC-Lch-049648	Latimeria chalumnae	34.85	3.00e-119	421.00
IUUC-Lpe-051523	Leersia perrieri	33.49	6.00e-107	379.00
IUUC-Loc-052072	Lepisosteus oculatus	31.18	3.00e-110	391.00
IUUC-Lma-053216	Leptosphaeria maculans	58.67	0.00e+00	924.00
IUUC-Laf-054327	Loxodonta africana	33.87	7.00e-124	436.00
IUUC-Mcc-055443	Macaca mulatta	33.64	1.00e-123	435.00
IUUC-Meu-056298	Macropus eugenii	32.59	2.00e-82	298.00
IUUC-Mor-057106	Magnaporthe oryzae	58.12	0.00e+00	936.00
IUUC-Mpo-057589	Magnaporthe poae	57.50	0.00e+00	896.00
IUUC-Mtr-058680	Medicago truncatula	34.96	6.00e-119	419.00
IUUC-Mla-058903	Melampsora laricipopulina	44.10	0.00e+00	641.00
IUUC-Mga-059669	Meleagris gallopavo	33.89	1.00e-119	422.00
IUUC-Mvi-060476	Microbotryum violaceum	43.57	2.00e-167	581.00
IUUC-Mmr-060575	Microcebus murinus	33.80	4.00e-124	437.00
IUUC-Mdo-062183	Monodelphis domestica	33.33	3.00e-124	437.00
IUUC-Mmu-063592	Mus musculus	33.53	2.00e-124	438.00
IUUC-Mac-065446	Musa acuminata	30.76	1.00e-100	358.00
IUUC-Mpu-066082	Mustela putorius furo	34.44	4.00e-127	447.00
IUUC-Mlu-067345	Myotis lucifugus	33.41	1.00e-121	429.00
IUUC-Nfi-068558	Neosartorya fischeri	71.33	0.00e+00	1105.00
IUUC-Ncr-068960	Neurospora crassa	60.20	0.00e+00	933.00
IUUC-Nle-070173	Nomascus leucogenys	34.28	1.00e-126	445.00
IUUC-Opr-070556	Ochotona princeps	34.11	3.00e-124	437.00
IUUC-Ont-071502	Oreochromis niloticus	33.21	2.00e-112	398.00
IUUC-Oan-072959	Ornithorhynchus anatinus	41.78	1.00e-45	174.00
IUUC-Ocu-074861	Oryctolagus cuniculus	34.44	2.00e-126	444.00
IUUC-Oba-075109	Oryza barthii	33.41	4.00e-109	387.00
IUUC-Obr-076292	Oryza brachyantha	33.21	7.00e-104	369.00
IUUC-Ogl-077065	Oryza glaberrima	34.35	6.00e-115	406.00
IUUC-Ogu-078776	Oryza glumaepatula	33.50	2.00e-112	398.00
IUUC-Oin-080048	Oryza indica	34.07	2.00e-113	401.00
IUUC-Olo-080711	Oryza longistaminata	32.87	2.00e-100	358.00
IUUC-Ome-081506	Oryza meridionalis	33.59	5.00e-103	366.00
IUUC-Oni-082320	Oryza nivara	32.54	8.00e-108	382.00
IUUC-Opu-083801	Oryza punctata	33.05	2.00e-103	368.00
IUUC-Oru-085139	Oryza rufipogon	32.78	4.00e-108	384.00
IUUC-Osa-085713	Oryza sativa	34.47	4.00e-116	410.00
IUUC-Ola-086951	Oryzias latipes	31.89	1.00e-104	372.00
IUUC-Olu-087822	Ostreococcus lucimarinus	31.62	3.00e-91	328.00
IUUC-Oga-088625	Otolemur garnettii	33.18	1.00e-122	432.00
IUUC-Oar-089995	Ovis aries	33.33	9.00e-122	429.00
IUUC-Ptr-090640	Pan troglodytes	34.48	6.00e-126	442.00
IUUC-Pan-091974	Papio anubis	33.64	2.00e-123	434.00
IUUC-Psi-093957	Pelodiscus sinensis	33.88	1.00e-127	448.00
IUUC-Pma-094242	Petromyzon marinus	38.96	3.00e-66	243.00
IUUC-Pno-094835	Phaeosphaeria nodorum	58.78	0.00e+00	842.00
IUUC-Ppa-095901	Physcomitrella patens	35.18	1.00e-123	435.00
IUUC-Pfo-097148	Poecilia formosa	33.02	7.00e-112	396.00
IUUC-Pab-098068	Pongo abelii	31.64	3.00e-105	374.00
IUUC-Pop-098943	Populus trichocarpa	33.95	2.00e-115	408.00
IUUC-Pca-100738	Procavia capensis	34.57	1.00e-90	326.00
IUUC-Ppe-101315	Prunus persica	32.40	3.00e-109	387.00
IUUC-Pva-102154	Pteropus vampyrus	32.95	4.00e-120	423.00
IUUC-Pgr-103343	Puccinia graminis	43.93	3.00e-149	520.00
IUUC-Ptt-103928	Puccinia triticina	37.15	2.00e-139	488.00
IUUC-Pte-104306	Pyrenophora teres	59.09	0.00e+00	884.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	59.25	0.00e+00	910.00
IUUC-Rno-105801	Rattus norvegicus	33.87	5.00e-126	443.00
IUUC-Sce-106304	Saccharomyces cerevisiae	32.63	7.00e-113	399.00
IUUC-Sha-107635	Sarcophilus harrisii	33.61	7.00e-124	436.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	40.71	4.00e-167	580.00
IUUC-Spo-108144	Schizosaccharomyces pombe	40.48	3.00e-173	600.00
IUUC-Smo-108703	Selaginella moellendorffii	35.81	3.00e-116	410.00
IUUC-Sit-110728	Setaria italica	33.33	1.00e-115	408.00
IUUC-Sly-111523	Solanum lycopersicum	34.19	5.00e-120	423.00
IUUC-Sar-113733	Sorex araneus	35.85	6.00e-65	240.00
IUUC-Sbi-114419	Sorghum bicolor	33.62	5.00e-113	400.00
IUUC-Sre-115225	Sporisorium reilianum	42.28	1.00e-173	601.00
IUUC-Ssc-115686	Sus scrofa	33.60	4.00e-123	433.00
IUUC-Tgu-117346	Taeniopygia guttata	34.42	1.00e-123	435.00
IUUC-Tru-118350	Takifugu rubripes	30.93	4.00e-106	377.00
IUUC-Tsy-119278	Tarsius syrichta	32.01	3.00e-92	331.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.01	6.00e-103	366.00
IUUC-Tca-121585	Theobroma cacao	33.33	9.00e-113	399.00
IUUC-Tre-122043	Trichoderma reesei	58.68	0.00e+00	898.00
IUUC-Tvi-122303	Trichoderma virens	57.74	0.00e+00	907.00
IUUC-Tae-123798	Triticum aestivum	33.66	1.00e-113	402.00
IUUC-Tur-126732	Triticum urartu	31.53	2.00e-102	364.00
IUUC-Tme-126909	Tuber melanosporum	56.98	0.00e+00	907.00
IUUC-Tbe-127261	Tupaia belangeri	30.65	2.00e-70	258.00
IUUC-Ttr-128295	Tursiops truncatus	29.70	5.00e-91	327.00
IUUC-Uma-129599	Ustilago maydis	41.88	4.00e-174	603.00
IUUC-Vda-129688	Verticillium dahliae	58.91	0.00e+00	903.00
IUUC-Vpa-130170	Vicugna pacos	34.94	2.00e-52	199.00
IUUC-Vvi-131116	Vitis vinifera	33.05	1.00e-109	389.00
IUUC-Xtr-131953	Xenopus tropicalis	32.32	3.00e-109	387.00
IUUC-Xma-133837	Xiphophorus maculatus	33.13	1.00e-111	395.00
IUUC-Yli-134510	Yarrowia lipolytica	43.92	2.00e-176	610.00
IUUC-Zma-135786	Zea mays	33.29	5.00e-110	390.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence