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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063579
Ensembl Protein ID ENSMUSP00000006470.7
UniProt Accession F8WJ40; F8WJ40_MOUSE
Genbank Protein ID ENSMUSP00000006470
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AC167970
Gene Name Kmt2b; Wbp7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000006307.16 ENSMUST00000006470.13 ENSMUSP00000006470.7
ENSMUSG00000006307.16 ENSMUST00000108154.8 ENSMUSP00000103789.2
ENSMUSG00000006307.16 ENSMUST00000131002.1 ENSMUSP00000118486.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLMmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.40e-27 96.0 1256 1309
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++ +  wiC+ C ++
   Q: 1256 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRRRrhWICSACVRC 1309
           58********************************.55554444444******876 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG GGAAGPGGAE 60
PGEDTALLRL LGLRRGLRRL RRLWAGARVQ RGRGRGRGRG WGPNRGCMPE EESSDGESEE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063579|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGTGCCAAGA TGGCGGCGGC GGCGGGCGGC GGCAGTTGCC CCGGGCCTGG CTCCGCACGG 60
GGCCGCTTCC CGGGCCGGCC GCGGGGTTCC GGCGGGGGCG GGGGCCGCGG CGGCCGAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063579|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR011989--ARM-like
IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 88.32 0.00e+00 3142.00
IUUC-Aca-004718 Anolis carolinensis 55.29 0.00e+00 2107.00
IUUC-Ame-010705 Astyanax mexicanus 44.03 0.00e+00 933.00
IUUC-Bta-013578 Bos taurus 91.06 0.00e+00 2878.00
IUUC-Bdi-014882 Brachypodium distachyon 33.33 1.00e-27 118.00
IUUC-Bra-017422 Brassica rapa 33.81 8.00e-28 119.00
IUUC-Cja-019138 Callithrix jacchus 87.56 0.00e+00 3201.00
IUUC-Cfa-020020 Canis familiaris 89.73 0.00e+00 3107.00
IUUC-Cpo-021552 Cavia porcellus 89.08 0.00e+00 3185.00
IUUC-Csa-024216 Chlorocebus sabaeus 90.05 0.00e+00 2466.00
IUUC-Cho-024565 Choloepus hoffmanni 75.78 4.00e-164 573.00
IUUC-Dre-027440 Danio rerio 48.21 0.00e+00 775.00
IUUC-Dno-029583 Dasypus novemcinctus 88.21 0.00e+00 3174.00
IUUC-Dor-030903 Dipodomys ordii 87.56 0.00e+00 2170.00
IUUC-Dme-032023 Drosophila melanogaster 46.99 2.00e-92 336.00
IUUC-Eca-034026 Equus caballus 93.40 0.00e+00 1925.00
IUUC-Eeu-034687 Erinaceus europaeus 90.96 0.00e+00 1108.00
IUUC-Fca-036311 Felis catus 89.97 0.00e+00 3200.00
IUUC-Gmo-039265 Gadus morhua 45.29 0.00e+00 827.00
IUUC-Gac-042202 Gasterosteus aculeatus 49.38 0.00e+00 764.00
IUUC-Ggo-044791 Gorilla gorilla 91.56 0.00e+00 2096.00
IUUC-Hsa-046988 Homo sapiens 89.93 0.00e+00 2417.00
IUUC-Hvu-047762 Hordeum vulgare 36.57 4.00e-20 92.80
IUUC-Itr-048907 Ictidomys tridecemlineatus 91.80 0.00e+00 3344.00
IUUC-Lpe-051476 Leersia perrieri 31.51 3.00e-24 107.00
IUUC-Loc-052252 Lepisosteus oculatus 54.24 0.00e+00 786.00
IUUC-Laf-053703 Loxodonta africana 91.24 0.00e+00 2152.00
IUUC-Mcc-054782 Macaca mulatta 89.03 0.00e+00 2452.00
IUUC-Meu-056046 Macropus eugenii 78.53 0.00e+00 1870.00
IUUC-Mmr-061316 Microcebus murinus 89.00 0.00e+00 2800.00
IUUC-Mdo-062648 Monodelphis domestica 79.14 0.00e+00 2703.00
IUUC-Mac-064935 Musa acuminata 32.02 5.00e-30 126.00
IUUC-Mpu-066710 Mustela putorius furo 89.71 0.00e+00 3147.00
IUUC-Mlu-067559 Myotis lucifugus 88.57 0.00e+00 2412.00
IUUC-Nle-070085 Nomascus leucogenys 87.52 0.00e+00 2136.00
IUUC-Opr-071148 Ochotona princeps 85.78 0.00e+00 3179.00
IUUC-Ont-071626 Oreochromis niloticus 45.68 0.00e+00 913.00
IUUC-Ocu-074475 Oryctolagus cuniculus 86.90 0.00e+00 3081.00
IUUC-Obr-076458 Oryza brachyantha 34.48 3.00e-28 120.00
IUUC-Ogl-077851 Oryza glaberrima 36.26 2.00e-28 120.00
IUUC-Ogu-078706 Oryza glumaepatula 36.26 1.00e-28 122.00
IUUC-Oin-079802 Oryza indica 31.43 2.00e-23 104.00
IUUC-Osa-085421 Oryza sativa 36.26 4.00e-28 120.00
IUUC-Ola-086609 Oryzias latipes 52.09 0.00e+00 766.00
IUUC-Oga-088140 Otolemur garnettii 89.94 0.00e+00 3173.00
IUUC-Oar-089447 Ovis aries 90.89 0.00e+00 1993.00
IUUC-Ptr-090902 Pan troglodytes 89.93 0.00e+00 2423.00
IUUC-Pan-091930 Papio anubis 90.05 0.00e+00 2475.00
IUUC-Ppa-095221 Physcomitrella patens 36.54 6.00e-31 129.00
IUUC-Pfo-096884 Poecilia formosa 46.75 0.00e+00 910.00
IUUC-Pab-098404 Pongo abelii 76.86 0.00e+00 1622.00
IUUC-Pop-099585 Populus trichocarpa 33.83 1.00e-26 115.00
IUUC-Pca-100949 Procavia capensis 82.35 0.00e+00 1220.00
IUUC-Ppe-101920 Prunus persica 33.50 5.00e-28 119.00
IUUC-Pva-102634 Pteropus vampyrus 89.44 0.00e+00 3215.00
IUUC-Rno-105870 Rattus norvegicus 97.75 0.00e+00 3642.00
IUUC-Sit-110552 Setaria italica 34.33 6.00e-29 122.00
IUUC-Sar-113289 Sorex araneus 87.52 0.00e+00 1744.00
IUUC-Ssc-115509 Sus scrofa 89.03 0.00e+00 3161.00
IUUC-Tru-117736 Takifugu rubripes 45.17 0.00e+00 837.00
IUUC-Tca-121624 Theobroma cacao 33.66 5.00e-28 119.00
IUUC-Tae-125629 Triticum aestivum 36.57 4.00e-20 93.20
IUUC-Tbe-127825 Tupaia belangeri 85.66 0.00e+00 1406.00
IUUC-Ttr-128754 Tursiops truncatus 91.76 0.00e+00 1216.00
IUUC-Xtr-132838 Xenopus tropicalis 49.19 0.00e+00 1004.00
IUUC-Xma-133119 Xiphophorus maculatus 44.36 0.00e+00 999.00
Created Date 25-Jun-2017

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