iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006359.4	ENSCAFT00000010286.4	ENSCAFP00000009537.3
ENSCAFG00000006359.4	ENSCAFT00000047399.1	ENSCAFP00000041584.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	9.00e-90	300.1	5	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v+kkkle+l++rYkdpq++ +igi+g+++fc+dl++dp++++vLv+awk++aat+cefs++ef+dg+t+lgcds+ekl++ l++le+el
   Q: 5    VDKKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLSLDPASVSVLVIAWKFKAATQCEFSKKEFVDGMTELGCDSTEKLRALLPRLEQEL 93
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd+ kfkd+Y+f+f+fak++gqk+ldl++a+a+w+L+l++r fk+ld+w++fL e++k+si++DtWnllL+f ++ia+d+snYdeegaW
   Q: 94   KDTVKFKDFYQFTFTFAKNPGQKGLDLEMAVAYWNLVLSGR-FKFLDLWNTFLLEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAW 181
           ****************************************9.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fvey+
   Q: 182  PVLIDDFVEYA 192
           *********97 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRDAVDKKKL EQLYNRYKDP QDENKIGIDG IQQFCDDLSL DPASVSVLVI AWKFKAATQC 60
EFSKKEFVDG MTELGCDSTE KLRALLPRLE QELKDTVKFK DFYQFTFTFA KNPGQKGLDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCCGGGAG ACCGTGTGTT TTCCTCAACT GATGAGGCAC GAGGCATGCT GTGCCGAGGT 60
TCTGCAGTGA AGCTGACCTG GTGGGAAACA ACGAAGTCCA GTTAGACCAC CAGCCATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001808	Ailuropoda melanoleuca	95.59	1.00e-115	408.00
IUUC-Atr-002662	Amborella trichopoda	40.00	7.00e-25	107.00
IUUC-Bta-012373	Bos taurus	89.50	3.00e-108	384.00
IUUC-Cho-024417	Choloepus hoffmanni	95.14	3.00e-102	363.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	30.53	2.00e-23	102.00
IUUC-Dre-027961	Danio rerio	83.33	3.00e-101	360.00
IUUC-Fca-035856	Felis catus	93.63	2.00e-114	404.00
IUUC-Fox-037884	Fusarium oxysporum	33.33	3.00e-18	84.70
IUUC-Fso-038150	Fusarium solani	31.66	6.00e-22	97.80
IUUC-Hvu-047636	Hordeum vulgare	37.21	1.00e-22	99.00
IUUC-Mac-065016	Musa acuminata	47.90	7.00e-44	169.00
IUUC-Mpu-066254	Mustela putorius furo	89.71	3.00e-110	390.00
IUUC-Pno-095145	Phaeosphaeria nodorum	32.86	3.00e-25	108.00
IUUC-Tre-121986	Trichoderma reesei	28.02	9.00e-22	97.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence