iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121586

Ensembl Protein ID

EOY06475

UniProt Accession

A0A061EN51; A0A061EN51_THECC

Genbank Protein ID

EOY06475.1

Protein Name

Cullin 1 isoform 1

Genbank Nucleotide ID

CM001882

Gene Name

TCM_021183

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_021183	EOY06475	EOY06475
TCM_021183	EOY06476	EOY06476

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	5.20e-151	505.3	25	647

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 2    lreavkkilrqesvkkeyeelytavynlclsk....vgaklYkklkevleefi.kqvkkkveesedeqlLktynreWekfreqlkvlrkifayldrtyvkk 97
           l+++++ + + + + ++y+ lyt +yn+c++k    ++++lY+k +e  ee+i   v  +  e++de +L+ +++ W +++  +  l + f yldr+++ +
   Q: 25   LKNILEGLPEPQFSSEDYMMLYTTIYNMCTQKpphdYSQQLYDKYRESFEEYItSTVLPSLREKHDEFMLRELVKRWANHKVMVRWLSRFFHYLDRYFIAR 125
           6667777777777899****************9*99*****************9899******************************************** PP
   S: 98   skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnklaiykesFEakfleatqefykaesaeflqenevdeYlk 198
            +++ + ++++l  +r+ + +++++++ ++++ li +eR+ge++dr ll++v   +ve+++ +   y+++FEa  l+ t+ +y++++++ + e ++ +Y+ 
   Q: 126  -RSLPPLNEVGLTCFRELVYQELNAKVRDAVISLIDQEREGEQIDRALLKNVLDIFVEIGMGQMDYYENDFEATMLKDTAAYYSRKASNWILEDSCPDYML 225
           .9*************************************************************************************************** PP
   S: 199  kvearlneeeeraaryleestetkLlevvekeliakhlesll....aelvallrdkktedlsrmykLlsrvlngleellkeleshikeqgkaaltaeekek 295
           k+e+ l+ e++r+++yl++s+e kLle+v++el++  ++ ll    ++++allrd+k edlsrm++L+ +++ gl+++ + +++h+  +g+a++ ++e + 
   Q: 226  KAEECLKREKDRVSHYLHSSSEPKLLEKVQHELLSVNANLLLekehSGCHALLRDDKVEDLSRMFRLFCKIPRGLDPVSGIFKQHVTAEGTALVKQAEDAA 326
           ***********************************999999999999************************************************444443 PP
   S: 296  .............dpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllv 382
                        + + +V++++el++k+   v+ +F+n + F kal++afe f nk   +  + s+EllA ++D+ L+k+ s +l +e +e++l+kv+ +
   Q: 327  snkkadkkdvvgmQEQVFVRKVIELHDKYLAYVNDCFQNHTLFHKALKEAFEVFCNKG--VAGSSSAELLATFCDNILKKGgSEKLSDEAIEETLEKVVKL 425
           45778899999997799*****************************************..7779999********************************** PP
   S: 383  fkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFkeeken.teesesvelsvlvLsagaWptaset 482
           + yis+kd+F ++Y+k La+RLl +ksa ++ E+s+++kLk++cg +ftsk+e+M++dl + ++ ++ F e  +n  +++++++l+v vL++g+Wp + + 
   Q: 426  LAYISDKDLFAEFYRKKLARRLLFDKSANDDHERSILTKLKQQCGGQFTSKMEGMVTDLTLARENQTSFDEYLSNnPNANPGIDLTVTVLTTGFWPSYKSF 526
           **********************************************************************9876515778******************775 PP
   S: 483  ekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgkyelqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvl 583
             ++LPae+ k +e f+ fY+ k ++RkL+W ++lg+++l  +++ ++ el V+t+Q+  LL+fn s+++s+ e+  + +l +++  r l sL + k ++l
   Q: 527  D-LNLPAEMIKCVEVFRDFYQTKTKHRKLTWIYSLGTCNLIGKFEPKTMELIVTTYQASALLLFNSSDRLSYSEIMTQLNLTDDDVVRLLHSLSCAKYKIL 626
           5.*************************************************************************************************** PP
   S: 584  kkepeskeieeedlfsvNqef 604
           +kep +k i+ +d f +N++f
   Q: 627  NKEPSTKTISPTDYFEFNSKF 647
           ******************998 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MTMNERKTID LEQGWEFMQK GITKLKNILE GLPEPQFSSE DYMMLYTTIY NMCTQKPPHD 60
YSQQLYDKYR ESFEEYITST VLPSLREKHD EFMLRELVKR WANHKVMVRW LSRFFHYLDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATGAGAAAG TAGAAGGACC TTCTTACAAA ATAAATAAAG TACGAACATG CAGGCATATA 60
ATCCTAAATA AAAAAAAAAG CTGCATTAAA AAACAAAAAA TAATTTAAAA AAGAAAATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000358	Aegilops tauschii	81.49	0.00e+00	1261.00
IUUC-Atr-002822	Amborella trichopoda	89.52	0.00e+00	1375.00
IUUC-Ago-007977	Ashbya gossypii	23.96	4.00e-64	238.00
IUUC-Bdi-014240	Brachypodium distachyon	86.69	0.00e+00	1333.00
IUUC-Cel-018294	Caenorhabditis elegans	30.20	3.00e-94	338.00
IUUC-Cre-022585	Chlamydomonas reinhardtii	65.95	0.00e+00	975.00
IUUC-Csv-026083	Ciona savignyi	31.34	2.00e-103	369.00
IUUC-Gma-044070	Glycine max	93.95	0.00e+00	1436.00
IUUC-Hvu-047383	Hordeum vulgare	86.42	0.00e+00	1333.00
IUUC-Lpe-051606	Leersia perrieri	86.60	0.00e+00	1310.00
IUUC-Mtr-057953	Medicago truncatula	92.18	0.00e+00	1402.00
IUUC-Mla-059021	Melampsora laricipopulina	31.63	4.00e-94	338.00
IUUC-Mac-065440	Musa acuminata	92.88	0.00e+00	1420.00
IUUC-Oba-075744	Oryza barthii	86.42	0.00e+00	1325.00
IUUC-Obr-076289	Oryza brachyantha	87.02	0.00e+00	1305.00
IUUC-Ogl-077579	Oryza glaberrima	83.20	0.00e+00	1276.00
IUUC-Ogu-078249	Oryza glumaepatula	85.87	0.00e+00	1323.00
IUUC-Oin-079171	Oryza indica	83.20	0.00e+00	1276.00
IUUC-Olo-080532	Oryza longistaminata	86.00	0.00e+00	1324.00
IUUC-Ome-081358	Oryza meridionalis	86.00	0.00e+00	1324.00
IUUC-Oni-082083	Oryza nivara	86.00	0.00e+00	1324.00
IUUC-Opu-083214	Oryza punctata	87.23	0.00e+00	1337.00
IUUC-Oru-085124	Oryza rufipogon	86.00	0.00e+00	1324.00
IUUC-Osa-085572	Oryza sativa	86.69	0.00e+00	1331.00
IUUC-Olu-087721	Ostreococcus lucimarinus	55.30	0.00e+00	831.00
IUUC-Pma-094502	Petromyzon marinus	30.97	2.00e-98	352.00
IUUC-Pno-095067	Phaeosphaeria nodorum	30.78	9.00e-98	350.00
IUUC-Ppa-095910	Physcomitrella patens	83.15	0.00e+00	1268.00
IUUC-Pop-100087	Populus trichocarpa	97.04	0.00e+00	1439.00
IUUC-Pca-100242	Procavia capensis	32.87	4.00e-74	272.00
IUUC-Ppe-101405	Prunus persica	95.03	0.00e+00	1451.00
IUUC-Pgr-103297	Puccinia graminis	30.96	5.00e-95	341.00
IUUC-Sce-106293	Saccharomyces cerevisiae	23.88	9.00e-61	227.00
IUUC-Smo-109541	Selaginella moellendorffii	83.24	0.00e+00	1228.00
IUUC-Sit-110264	Setaria italica	84.70	0.00e+00	1206.00
IUUC-Sly-111067	Solanum lycopersicum	93.53	0.00e+00	1421.00
IUUC-Stu-112374	Solanum tuberosum	84.55	0.00e+00	1244.00
IUUC-Sbi-114502	Sorghum bicolor	86.69	0.00e+00	1331.00
IUUC-Tae-125618	Triticum aestivum	83.42	0.00e+00	1318.00
IUUC-Tur-126475	Triticum urartu	77.39	0.00e+00	1240.00
IUUC-Vvi-131423	Vitis vinifera	96.24	0.00e+00	1461.00
IUUC-Yli-134486	Yarrowia lipolytica	27.86	2.00e-82	300.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence