iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133347

Ensembl Protein ID

ENSXMAP00000019014.1

UniProt Accession

M4AX19; M4AX19_XIPMA

Genbank Protein ID

ENSXMAP00000019014

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AGAJ01004091

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000018937.1	ENSXMAT00000019042.1	ENSXMAP00000019014.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.40e-34	114.8	183	224
UBD/Beta-Prp	4.00e-73	246.2	13	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD ++k+WD+   +++++
   Q: 183  GHEKGVNCIDYysgGDkPYLISGADDRQVKIWDYQNKTCVQT 224
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ +tg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRASKFVARKNWVITGADDMQIRVFNYNTLERVHMFEAHSDY 101
           678999*********************************************************************************** PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvy 184
           +++++++p++ ++++ s+d  i++wd+e+++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+
   Q: 102  IRCIAVHPTQPYILTSSDDMLIKLWDWEKKWTCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVN 189
           ******************************99999**********************************************9.****** PP
   S: 185  slsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisva 271
           ++++ s g  ++l+sg++d++vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++v+
   Q: 190  CIDYYSGGdkPYLISGADDRQVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVC 278
           ***8887777******************************************************************************* PP
   S: 272  vlsfgdnvlvlg 283
           +l+ ++nv +  
   Q: 279  GLRGSNNVALGY 290
           *99999987433 PP

Organism

Xiphophorus maculatus

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRR LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RASKFVARKN WVITGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPYILTSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGAAGTT CCACGTCAGT ATCCAATGCA CTGCTCTCTG TAATTGTAAC CCCCCGACCG 60
AAGTGATAGC AACGTTTTTA TTCAATCAGA CTGCGATAAC ACGGGGTTAA AACATGGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030903--P:notochord development
GO:0061053--P:somite development
GO:0016192--P:vesicle-mediated transport

KEGG

xma:102238024

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	53.27	0.00e+00	935.00
IUUC-Aml-002154	Ailuropoda melanoleuca	87.46	0.00e+00	1679.00
IUUC-Atr-003090	Amborella trichopoda	58.73	0.00e+00	1068.00
IUUC-Apl-003976	Anas platyrhynchos	90.83	0.00e+00	1688.00
IUUC-Aca-004301	Anolis carolinensis	93.62	0.00e+00	1677.00
IUUC-Aly-006508	Arabidopsis lyrata	61.11	0.00e+00	1091.00
IUUC-Ath-007630	Arabidopsis thaliana	61.86	0.00e+00	1108.00
IUUC-Ago-007914	Ashbya gossypii	46.62	0.00e+00	756.00
IUUC-Acl-008237	Aspergillus clavatus	56.38	0.00e+00	962.00
IUUC-Afl-008535	Aspergillus flavus	56.03	0.00e+00	911.00
IUUC-Afu-008845	Aspergillus fumigatus	54.87	0.00e+00	936.00
IUUC-Ani-009135	Aspergillus nidulans	56.10	0.00e+00	913.00
IUUC-Ang-009654	Aspergillus niger	55.75	0.00e+00	856.00
IUUC-Aor-009939	Aspergillus oryzae	53.58	0.00e+00	967.00
IUUC-Ate-010355	Aspergillus terreus	54.69	0.00e+00	914.00
IUUC-Ame-010922	Astyanax mexicanus	86.95	0.00e+00	1553.00
IUUC-Bgr-012249	Blumeria graminis	53.88	0.00e+00	920.00
IUUC-Bta-013579	Bos taurus	95.23	0.00e+00	1442.00
IUUC-Bci-013866	Botrytis cinerea	55.07	0.00e+00	920.00
IUUC-Bdi-015046	Brachypodium distachyon	62.67	0.00e+00	1104.00
IUUC-Bol-015731	Brassica oleracea	61.06	0.00e+00	1108.00
IUUC-Bra-016617	Brassica rapa	61.12	0.00e+00	1078.00
IUUC-Cel-018387	Caenorhabditis elegans	65.13	0.00e+00	1177.00
IUUC-Cja-019145	Callithrix jacchus	87.79	0.00e+00	1680.00
IUUC-Cfa-020564	Canis familiaris	87.69	0.00e+00	1673.00
IUUC-Cpo-022201	Cavia porcellus	93.13	0.00e+00	1668.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	59.32	0.00e+00	986.00
IUUC-Csa-023383	Chlorocebus sabaeus	94.00	0.00e+00	1146.00
IUUC-Cho-024454	Choloepus hoffmanni	88.44	0.00e+00	1365.00
IUUC-Cin-025681	Ciona intestinalis	78.08	0.00e+00	1368.00
IUUC-Csv-026012	Ciona savignyi	76.25	0.00e+00	1341.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.24	0.00e+00	839.00
IUUC-Cne-026986	Cryptococcus neoformans	50.85	0.00e+00	909.00
IUUC-Cme-027219	Cyanidioschyzon merolae	48.05	0.00e+00	855.00
IUUC-Dre-027846	Danio rerio	95.34	0.00e+00	1727.00
IUUC-Dor-030462	Dipodomys ordii	89.17	0.00e+00	1240.00
IUUC-Dse-031268	Dothistroma septosporum	54.84	0.00e+00	949.00
IUUC-Dme-031791	Drosophila melanogaster	72.27	0.00e+00	1268.00
IUUC-Ete-033166	Echinops telfairi	84.95	0.00e+00	986.00
IUUC-Eca-034180	Equus caballus	91.01	0.00e+00	1618.00
IUUC-Eeu-035086	Erinaceus europaeus	76.10	0.00e+00	801.00
IUUC-Fca-036265	Felis catus	87.37	0.00e+00	1680.00
IUUC-Fal-037202	Ficedula albicollis	94.01	0.00e+00	1632.00
IUUC-Fox-037711	Fusarium oxysporum	55.79	0.00e+00	877.00
IUUC-Fso-038268	Fusarium solani	55.51	0.00e+00	877.00
IUUC-Gmo-039046	Gadus morhua	96.33	0.00e+00	1717.00
IUUC-Ggr-039863	Gaeumannomyces graminis	55.11	0.00e+00	896.00
IUUC-Gga-041112	Gallus gallus	92.26	0.00e+00	1692.00
IUUC-Gac-041733	Gasterosteus aculeatus	97.31	0.00e+00	1717.00
IUUC-Gma-042910	Glycine max	62.39	0.00e+00	1117.00
IUUC-Ggo-044984	Gorilla gorilla	87.58	0.00e+00	1670.00
IUUC-Hsa-046698	Homo sapiens	87.58	0.00e+00	1674.00
IUUC-Hvu-047669	Hordeum vulgare	70.34	1.00e-167	582.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	87.78	0.00e+00	1670.00
IUUC-Kpa-049265	Komagataella pastoris	49.56	0.00e+00	867.00
IUUC-Lch-050473	Latimeria chalumnae	88.65	0.00e+00	1712.00
IUUC-Lpe-051579	Leersia perrieri	61.23	0.00e+00	1091.00
IUUC-Loc-052675	Lepisosteus oculatus	95.18	0.00e+00	1712.00
IUUC-Lma-053218	Leptosphaeria maculans	54.96	0.00e+00	924.00
IUUC-Laf-053757	Loxodonta africana	87.38	0.00e+00	1667.00
IUUC-Mcc-054859	Macaca mulatta	87.79	0.00e+00	1679.00
IUUC-Meu-056174	Macropus eugenii	90.26	0.00e+00	712.00
IUUC-Mor-057264	Magnaporthe oryzae	55.23	0.00e+00	881.00
IUUC-Mpo-057538	Magnaporthe poae	55.36	0.00e+00	909.00
IUUC-Mtr-058310	Medicago truncatula	62.52	0.00e+00	1126.00
IUUC-Mla-058937	Melampsora laricipopulina	53.21	0.00e+00	901.00
IUUC-Mga-059875	Meleagris gallopavo	92.05	0.00e+00	1686.00
IUUC-Mvi-060240	Microbotryum violaceum	50.68	0.00e+00	904.00
IUUC-Mmr-061261	Microcebus murinus	87.69	0.00e+00	1680.00
IUUC-Mdo-062076	Monodelphis domestica	90.35	0.00e+00	1689.00
IUUC-Mmu-063324	Mus musculus	87.69	0.00e+00	1678.00
IUUC-Mac-064636	Musa acuminata	59.33	0.00e+00	1084.00
IUUC-Mpu-065961	Mustela putorius furo	86.83	0.00e+00	1675.00
IUUC-Mlu-067059	Myotis lucifugus	92.54	0.00e+00	1616.00
IUUC-Nfi-068277	Neosartorya fischeri	54.58	0.00e+00	924.00
IUUC-Ncr-068659	Neurospora crassa	52.95	0.00e+00	910.00
IUUC-Nle-069034	Nomascus leucogenys	87.79	0.00e+00	1679.00
IUUC-Opr-070334	Ochotona princeps	94.69	0.00e+00	1478.00
IUUC-Ont-071563	Oreochromis niloticus	93.89	0.00e+00	1778.00
IUUC-Oan-073416	Ornithorhynchus anatinus	93.40	0.00e+00	1603.00
IUUC-Ocu-074522	Oryctolagus cuniculus	87.69	0.00e+00	1672.00
IUUC-Oba-075760	Oryza barthii	60.99	0.00e+00	1075.00
IUUC-Obr-076163	Oryza brachyantha	62.84	0.00e+00	1099.00
IUUC-Ogl-077450	Oryza glaberrima	62.22	0.00e+00	1102.00
IUUC-Ogu-078994	Oryza glumaepatula	60.99	0.00e+00	1073.00
IUUC-Oin-079856	Oryza indica	60.63	0.00e+00	1075.00
IUUC-Olo-080731	Oryza longistaminata	59.07	0.00e+00	1061.00
IUUC-Ome-081762	Oryza meridionalis	56.60	0.00e+00	997.00
IUUC-Oni-082324	Oryza nivara	60.99	0.00e+00	1074.00
IUUC-Opu-083400	Oryza punctata	58.56	0.00e+00	1060.00
IUUC-Oru-084829	Oryza rufipogon	60.99	0.00e+00	1074.00
IUUC-Osa-086026	Oryza sativa	62.22	0.00e+00	1105.00
IUUC-Ola-087245	Oryzias latipes	94.44	0.00e+00	1807.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.60	0.00e+00	1051.00
IUUC-Oga-088163	Otolemur garnettii	84.81	0.00e+00	1606.00
IUUC-Oar-089842	Ovis aries	93.14	0.00e+00	1671.00
IUUC-Ptr-090501	Pan troglodytes	87.79	0.00e+00	1674.00
IUUC-Pan-092011	Papio anubis	87.90	0.00e+00	1681.00
IUUC-Psi-093308	Pelodiscus sinensis	94.00	0.00e+00	1691.00
IUUC-Pma-094695	Petromyzon marinus	81.13	0.00e+00	1442.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.07	3.00e-111	395.00
IUUC-Ppa-095911	Physcomitrella patens	61.48	0.00e+00	1124.00
IUUC-Pfo-096587	Poecilia formosa	97.64	0.00e+00	1877.00
IUUC-Pab-097926	Pongo abelii	85.62	0.00e+00	1585.00
IUUC-Pop-099634	Populus trichocarpa	62.15	0.00e+00	1108.00
IUUC-Pca-100965	Procavia capensis	86.28	0.00e+00	1629.00
IUUC-Ppe-101470	Prunus persica	61.91	0.00e+00	1111.00
IUUC-Pva-102451	Pteropus vampyrus	88.42	0.00e+00	1231.00
IUUC-Pgr-103453	Puccinia graminis	52.83	0.00e+00	916.00
IUUC-Ptt-103868	Puccinia triticina	53.18	0.00e+00	915.00
IUUC-Pte-104274	Pyrenophora teres	55.76	0.00e+00	955.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	55.11	0.00e+00	903.00
IUUC-Rno-105979	Rattus norvegicus	81.00	0.00e+00	1226.00
IUUC-Sce-106269	Saccharomyces cerevisiae	47.17	0.00e+00	782.00
IUUC-Sha-106905	Sarcophilus harrisii	91.22	0.00e+00	1686.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	47.59	0.00e+00	830.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.40	0.00e+00	824.00
IUUC-Smo-108695	Selaginella moellendorffii	62.22	0.00e+00	1079.00
IUUC-Sit-110239	Setaria italica	59.12	0.00e+00	1105.00
IUUC-Sly-111525	Solanum lycopersicum	61.31	0.00e+00	1117.00
IUUC-Stu-112906	Solanum tuberosum	59.97	0.00e+00	991.00
IUUC-Sar-113472	Sorex araneus	87.38	0.00e+00	1124.00
IUUC-Sbi-114052	Sorghum bicolor	63.16	0.00e+00	1116.00
IUUC-Sre-115040	Sporisorium reilianum	51.68	0.00e+00	912.00
IUUC-Ssc-115593	Sus scrofa	87.69	0.00e+00	1681.00
IUUC-Tgu-117239	Taeniopygia guttata	93.97	0.00e+00	1689.00
IUUC-Tru-118025	Takifugu rubripes	96.96	0.00e+00	1746.00
IUUC-Tsy-118824	Tarsius syrichta	86.78	0.00e+00	1134.00
IUUC-Tni-120142	Tetraodon nigroviridis	95.19	0.00e+00	1744.00
IUUC-Tca-121613	Theobroma cacao	61.79	0.00e+00	1110.00
IUUC-Tre-122072	Trichoderma reesei	55.11	0.00e+00	926.00
IUUC-Tvi-122546	Trichoderma virens	54.61	0.00e+00	912.00
IUUC-Tae-125292	Triticum aestivum	61.78	0.00e+00	1094.00
IUUC-Tur-126283	Triticum urartu	54.14	0.00e+00	934.00
IUUC-Tme-127041	Tuber melanosporum	55.88	0.00e+00	974.00
IUUC-Tbe-127770	Tupaia belangeri	89.01	0.00e+00	1238.00
IUUC-Ttr-129294	Tursiops truncatus	87.69	0.00e+00	1679.00
IUUC-Uma-129351	Ustilago maydis	50.79	0.00e+00	903.00
IUUC-Vda-129716	Verticillium dahliae	55.24	0.00e+00	946.00
IUUC-Vpa-130037	Vicugna pacos	77.31	0.00e+00	834.00
IUUC-Vvi-131689	Vitis vinifera	62.70	0.00e+00	1106.00
IUUC-Xtr-132633	Xenopus tropicalis	89.69	0.00e+00	1670.00
IUUC-Yli-134455	Yarrowia lipolytica	51.02	0.00e+00	843.00
IUUC-Zma-135706	Zea mays	60.68	0.00e+00	1116.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence