iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000000913.1	ENSFALT00000000959.1	ENSFALP00000000954.1
ENSFALG00000000913.1	ENSFALT00000000960.1	ENSFALP00000000955.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UFD/PB1	28.89	2.80e-01	28.50	IUUC-Ots-000022

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MQNPSWIFDP PEELERKVQE LAELIRSSSN VVFHTGAGIS TASGIPDFRG PNGVWTMEEK 60
GLSPKFDTTF ENARPSKTHM ALLGLQRVGI LKFLVSQNVD GLHVRSGFPR DKLAELHGNM 120

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Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCGCGGCT CCCTCCTTGT CCCCCTGCCG TGGGTGTCTG TCCCCAGAGT GCCGTGGTTC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR029035--DHS-like_NAD/FAD-binding_dom
IPR003000--Sirtuin
IPR026590--Ssirtuin_cat_dom

PROSITE

PS50305--SIRTUIN

Pfam

PF02146--SIR2

Gene Ontology

GO:0005724--C:nuclear telomeric heterochromatin
GO:0005654--C:nucleoplasm
GO:0003682--F:chromatin binding
GO:0003956--F:NAD(P)+-protein-arginine ADP-ribosyltransferase activity
GO:0070403--F:NAD+ binding
GO:0046969--F:NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0003714--F:transcription corepressor activity
GO:0006284--P:base-excision repair
GO:0042593--P:glucose homeostasis
GO:0008285--P:negative regulation of cell proliferation
GO:0046325--P:negative regulation of glucose import
GO:0045820--P:negative regulation of glycolytic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1905555--P:positive regulation blood vessel branching
GO:1902732--P:positive regulation of chondrocyte proliferation
GO:0031940--P:positive regulation of chromatin silencing at telomere
GO:0048146--P:positive regulation of fibroblast proliferation
GO:2000648--P:positive regulation of stem cell proliferation
GO:0032206--P:positive regulation of telomere maintenance
GO:1905549--P:positive regulation of telomeric heterochromatin assembly
GO:1905564--P:positive regulation of vascular endothelial cell proliferation
GO:0006471--P:protein ADP-ribosylation
GO:0031648--P:protein destabilization
GO:0010569--P:regulation of double-strand break repair via homologous recombination

KEGG

fab:101814833

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000756	Aegilops tauschii	32.50	7.70e-01	26.60
IUUC-Mtr-058557	Medicago truncatula	31.11	4.00e-01	27.30
IUUC-Tgu-117509	Taeniopygia guttata	93.16	7.00e-144	502.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence