iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062282

Ensembl Protein ID

ENSMODP00000010747.1

UniProt Accession

F6PGK8; F6PGK8_MONDO

Protein Name

Inhibitor of growth protein

Gene Name

ING5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008639.3	ENSMODT00000010959.2	ENSMODP00000010747.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-09	37.1	187	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C  ewfH+aC+ l+   ++p+ + w+Cp+C +
   Q: 187  TYC-LCHQVSYGE--MIGCDNpdCPiEWFHFACVDLT---TKPKGK-WFCPRCVQ 234
           69*.*******99..*********99***********...999997.******87 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MATAMYLEHY LDSIENLPCE LQRNFQLMRE LDQRTEDKKA EIDSLAAEYI STVKTLSPEQ 60
RVEHLQKIQT AYSKCKEYSD DKVQLAMQTY EMVDKHIRRL DADLARFEAD LKEKMEGSDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGGTGGG CGGGGCCTCC GACGCGGGGG CGGAGCCTCC CCTGCGCCTG GCACGCAAGC 60
CAATCAGACG GCGCCCCTCA TGAATAGGGA ATGAAGCTGC GGCGGCCCGA CAGCGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:2001235--P:positive regulation of apoptotic signaling pathway

KEGG

mdo:100010106

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002381	Ailuropoda melanoleuca	96.05	3.00e-109	387.00
IUUC-Atr-002906	Amborella trichopoda	32.65	2.00e-32	132.00
IUUC-Apl-003516	Anas platyrhynchos	90.20	1.00e-96	345.00
IUUC-Aca-005009	Anolis carolinensis	85.29	4.00e-107	380.00
IUUC-Ame-011879	Astyanax mexicanus	77.18	5.00e-103	367.00
IUUC-Bta-012590	Bos taurus	93.83	3.00e-111	394.00
IUUC-Bol-015245	Brassica oleracea	32.37	1.00e-29	123.00
IUUC-Bra-017027	Brassica rapa	32.78	3.00e-30	124.00
IUUC-Cja-019518	Callithrix jacchus	95.00	1.00e-119	422.00
IUUC-Cfa-020620	Canis familiaris	95.83	2.00e-124	437.00
IUUC-Cpo-022085	Cavia porcellus	95.76	1.00e-115	408.00
IUUC-Csa-023421	Chlorocebus sabaeus	96.25	8.00e-117	412.00
IUUC-Cin-025479	Ciona intestinalis	64.22	5.00e-79	286.00
IUUC-Csv-026288	Ciona savignyi	55.30	3.00e-76	278.00
IUUC-Dre-027588	Danio rerio	76.03	4.00e-103	367.00
IUUC-Eca-033493	Equus caballus	92.95	3.00e-112	397.00
IUUC-Fca-035635	Felis catus	92.73	2.00e-54	205.00
IUUC-Fal-036998	Ficedula albicollis	90.00	3.00e-111	394.00
IUUC-Gmo-039035	Gadus morhua	75.93	2.00e-98	351.00
IUUC-Gga-040578	Gallus gallus	90.83	8.00e-120	422.00
IUUC-Gac-042172	Gasterosteus aculeatus	75.10	8.00e-102	362.00
IUUC-Hsa-045965	Homo sapiens	96.25	8.00e-117	412.00
IUUC-Lpe-050822	Leersia perrieri	36.99	8.00e-38	150.00
IUUC-Loc-052725	Lepisosteus oculatus	82.92	5.00e-101	360.00
IUUC-Mcc-055455	Macaca mulatta	95.20	1.00e-108	385.00
IUUC-Mtr-058089	Medicago truncatula	32.10	6.00e-35	140.00
IUUC-Mga-059312	Meleagris gallopavo	89.60	1.00e-96	345.00
IUUC-Mmr-061351	Microcebus murinus	95.59	4.00e-108	384.00
IUUC-Mmu-063201	Mus musculus	92.50	7.00e-117	412.00
IUUC-Mac-064625	Musa acuminata	35.18	9.00e-37	146.00
IUUC-Mpu-066302	Mustela putorius furo	95.83	2.00e-117	414.00
IUUC-Mlu-068192	Myotis lucifugus	95.42	4.00e-118	416.00
IUUC-Ont-072055	Oreochromis niloticus	76.67	1.00e-98	352.00
IUUC-Oan-073652	Ornithorhynchus anatinus	96.05	1.00e-113	401.00
IUUC-Ocu-073871	Oryctolagus cuniculus	94.61	5.00e-119	419.00
IUUC-Obr-076266	Oryza brachyantha	35.86	5.00e-37	147.00
IUUC-Oin-079049	Oryza indica	35.63	9.00e-36	143.00
IUUC-Oni-082218	Oryza nivara	35.63	9.00e-36	143.00
IUUC-Ola-087103	Oryzias latipes	76.03	5.00e-95	340.00
IUUC-Oga-088066	Otolemur garnettii	85.31	3.00e-99	353.00
IUUC-Ptr-091665	Pan troglodytes	96.25	8.00e-117	412.00
IUUC-Pan-091875	Papio anubis	96.25	8.00e-117	412.00
IUUC-Psi-093904	Pelodiscus sinensis	93.43	1.00e-102	365.00
IUUC-Pfo-096981	Poecilia formosa	76.76	5.00e-98	350.00
IUUC-Pva-102282	Pteropus vampyrus	88.75	9.00e-120	422.00
IUUC-Rno-105646	Rattus norvegicus	92.50	9.00e-117	412.00
IUUC-Sha-107031	Sarcophilus harrisii	97.39	3.00e-112	397.00
IUUC-Smo-109441	Selaginella moellendorffii	34.92	1.00e-42	166.00
IUUC-Tgu-116837	Taeniopygia guttata	88.74	8.00e-111	392.00
IUUC-Tru-117974	Takifugu rubripes	76.03	7.00e-95	339.00
IUUC-Tni-120024	Tetraodon nigroviridis	76.35	6.00e-88	316.00
IUUC-Vvi-131487	Vitis vinifera	34.98	4.00e-33	134.00
IUUC-Xtr-132189	Xenopus tropicalis	84.10	2.00e-110	390.00
IUUC-Xma-133297	Xiphophorus maculatus	75.93	8.00e-97	346.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence