iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073351

UUCD1 version

UUC-OrA-00482

Ensembl Protein ID

ENSOANP00000024332.2

UniProt Accession

F7CMU2; F7CMU2_ORNAN

Protein Name

Uncharacterized protein

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000015459.3	ENSOANT00000041916.1	ENSOANP00000032668.1
ENSOANG00000015459.3	ENSOANT00000024336.2	ENSOANP00000024332.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	63.02	0.00e+00	1338.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.39	6.00e-41	164.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

VRPFKRIHLT ATDCQDLSRS QEGLSSLTQP FSQRRSSRDL NWGLYPSPRT KRWSEGRSSQ 60
RRVWDCFSAA LPPGSEAMAE APADHDGSQE ESGDVPVSSY EPRDGRCGAS RGAPGPSASC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN TTTCGATATG CATGGGGAGA ATGGGCAGCA GGCGGCACTG GACTTCTGGA 60
CGTTTGTGAG TCGAAGGGGA GGGAGCTGGA GGGTCAGGCG AATCATGGCC GTGGGTAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

SMART

SM00256--FBOX

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	38.81	3.00e-06	47.80
IUUC-Aml-001396	Ailuropoda melanoleuca	62.29	0.00e+00	1273.00
IUUC-Apl-003317	Anas platyrhynchos	53.20	0.00e+00	907.00
IUUC-Aca-004498	Anolis carolinensis	54.97	0.00e+00	971.00
IUUC-Ani-009226	Aspergillus nidulans	28.33	3.10e-02	33.90
IUUC-Ate-010526	Aspergillus terreus	21.71	8.00e-03	35.80
IUUC-Ame-011808	Astyanax mexicanus	56.69	1.00e-129	455.00
IUUC-Bta-013250	Bos taurus	62.10	0.00e+00	1266.00
IUUC-Bdi-014513	Brachypodium distachyon	48.57	3.00e-03	35.80
IUUC-Bol-016158	Brassica oleracea	40.82	2.00e-03	37.70
IUUC-Cja-019638	Callithrix jacchus	62.83	0.00e+00	1335.00
IUUC-Cfa-020195	Canis familiaris	64.04	0.00e+00	1259.00
IUUC-Cpo-022269	Cavia porcellus	60.23	0.00e+00	1209.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	34.72	4.00e-07	50.40
IUUC-Csa-024060	Chlorocebus sabaeus	67.49	0.00e+00	1219.00
IUUC-Cho-025003	Choloepus hoffmanni	66.67	4.00e-152	531.00
IUUC-Cin-025694	Ciona intestinalis	28.27	4.00e-32	131.00
IUUC-Dre-028083	Danio rerio	50.34	0.00e+00	851.00
IUUC-Dno-029203	Dasypus novemcinctus	60.76	0.00e+00	1203.00
IUUC-Dor-030477	Dipodomys ordii	74.68	4.00e-179	621.00
IUUC-Ete-032861	Echinops telfairi	62.56	0.00e+00	1267.00
IUUC-Eca-033205	Equus caballus	62.76	0.00e+00	1325.00
IUUC-Eeu-034784	Erinaceus europaeus	65.48	0.00e+00	931.00
IUUC-Fca-035797	Felis catus	62.17	0.00e+00	1290.00
IUUC-Gmo-038855	Gadus morhua	45.74	9.00e-119	421.00
IUUC-Gga-040326	Gallus gallus	49.76	0.00e+00	967.00
IUUC-Gac-042240	Gasterosteus aculeatus	45.34	0.00e+00	711.00
IUUC-Ggo-045050	Gorilla gorilla	59.87	0.00e+00	1216.00
IUUC-Hsa-046650	Homo sapiens	63.01	0.00e+00	1302.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	73.39	1.00e-173	601.00
IUUC-Lch-050231	Latimeria chalumnae	47.96	7.00e-153	533.00
IUUC-Lpe-051538	Leersia perrieri	39.39	1.40e-02	34.70
IUUC-Loc-051884	Lepisosteus oculatus	49.76	0.00e+00	1001.00
IUUC-Lma-053267	Leptosphaeria maculans	24.12	3.00e-05	43.90
IUUC-Laf-053843	Loxodonta africana	62.29	0.00e+00	1285.00
IUUC-Mcc-055570	Macaca mulatta	62.27	0.00e+00	1318.00
IUUC-Meu-056798	Macropus eugenii	57.72	4.00e-129	455.00
IUUC-Mtr-057915	Medicago truncatula	33.80	8.00e-03	36.20
IUUC-Mga-059648	Meleagris gallopavo	50.47	0.00e+00	934.00
IUUC-Mmr-060757	Microcebus murinus	62.35	0.00e+00	1273.00
IUUC-Mdo-061913	Monodelphis domestica	63.66	0.00e+00	1207.00
IUUC-Mmu-064337	Mus musculus	61.85	0.00e+00	1292.00
IUUC-Mac-064570	Musa acuminata	40.00	3.00e-04	38.90
IUUC-Mpu-066483	Mustela putorius furo	62.48	0.00e+00	1301.00
IUUC-Mlu-068204	Myotis lucifugus	59.06	0.00e+00	1222.00
IUUC-Nle-070053	Nomascus leucogenys	62.46	0.00e+00	1282.00
IUUC-Opr-070588	Ochotona princeps	59.14	0.00e+00	1198.00
IUUC-Ont-072655	Oreochromis niloticus	46.57	0.00e+00	748.00
IUUC-Ocu-074465	Oryctolagus cuniculus	62.45	0.00e+00	1234.00
IUUC-Oba-075140	Oryza barthii	53.85	2.00e-04	39.70
IUUC-Ogl-077337	Oryza glaberrima	53.85	2.00e-04	39.30
IUUC-Ogu-078861	Oryza glumaepatula	53.85	2.00e-04	39.70
IUUC-Oin-079568	Oryza indica	53.85	1.00e-04	39.30
IUUC-Olo-080883	Oryza longistaminata	41.46	4.00e-05	40.00
IUUC-Oni-082634	Oryza nivara	53.85	2.00e-04	40.00
IUUC-Opu-083155	Oryza punctata	45.00	5.00e-03	36.20
IUUC-Oru-084992	Oryza rufipogon	53.85	2.00e-04	40.00
IUUC-Olu-087831	Ostreococcus lucimarinus	33.45	2.00e-67	251.00
IUUC-Oga-089088	Otolemur garnettii	61.22	0.00e+00	1228.00
IUUC-Oar-089870	Ovis aries	61.81	0.00e+00	1238.00
IUUC-Ptr-090957	Pan troglodytes	63.08	0.00e+00	1291.00
IUUC-Pan-092632	Papio anubis	62.18	0.00e+00	1273.00
IUUC-Psi-093035	Pelodiscus sinensis	53.54	0.00e+00	1084.00
IUUC-Pno-094870	Phaeosphaeria nodorum	25.20	7.00e-04	39.30
IUUC-Ppa-095563	Physcomitrella patens	55.00	8.00e-06	44.30
IUUC-Pfo-096902	Poecilia formosa	43.78	0.00e+00	683.00
IUUC-Pab-098206	Pongo abelii	62.26	0.00e+00	1205.00
IUUC-Pop-098801	Populus trichocarpa	31.82	3.00e-04	40.40
IUUC-Pca-100238	Procavia capensis	57.71	0.00e+00	1183.00
IUUC-Ppe-101748	Prunus persica	35.21	3.40e-02	33.90
IUUC-Pva-103182	Pteropus vampyrus	62.50	0.00e+00	1281.00
IUUC-Pte-104033	Pyrenophora teres	23.57	4.00e-05	43.10
IUUC-Pyt-104599	Pyrenophora triticirepentis	23.57	3.00e-05	43.50
IUUC-Rno-105141	Rattus norvegicus	62.10	0.00e+00	1295.00
IUUC-Sce-106341	Saccharomyces cerevisiae	29.89	4.00e-04	39.70
IUUC-Sha-106827	Sarcophilus harrisii	59.73	0.00e+00	1238.00
IUUC-Sja-107882	Schizosaccharomyces japonicus	29.81	8.00e-40	158.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.39	2.00e-41	164.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	26.25	4.00e-04	39.70
IUUC-Sly-111170	Solanum lycopersicum	29.47	1.30e-01	30.80
IUUC-Sre-115025	Sporisorium reilianum	33.33	1.00e-36	148.00
IUUC-Ssc-116188	Sus scrofa	69.34	0.00e+00	941.00
IUUC-Tgu-116612	Taeniopygia guttata	54.43	3.00e-150	524.00
IUUC-Tsy-119560	Tarsius syrichta	65.73	2.00e-92	333.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.24	0.00e+00	695.00
IUUC-Tre-122089	Trichoderma reesei	32.84	6.00e-04	38.90
IUUC-Tae-125683	Triticum aestivum	38.16	1.00e-03	37.70
IUUC-Tur-126494	Triticum urartu	29.79	4.00e-05	42.40
IUUC-Tme-127009	Tuber melanosporum	31.33	1.00e-03	38.10
IUUC-Tbe-127431	Tupaia belangeri	61.61	0.00e+00	1079.00
IUUC-Ttr-128744	Tursiops truncatus	60.11	0.00e+00	1217.00
IUUC-Uma-129536	Ustilago maydis	33.44	1.00e-37	152.00
IUUC-Vpa-130123	Vicugna pacos	43.19	4.00e-35	142.00
IUUC-Vvi-131025	Vitis vinifera	33.80	1.10e-02	35.40
IUUC-Xtr-132902	Xenopus tropicalis	55.36	0.00e+00	963.00
IUUC-Xma-133978	Xiphophorus maculatus	44.43	3.00e-150	525.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence