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Tag Content
UUCD2 ID IUUC-Mlu-067392
UUCD1 version UUC-MyL-00066
Ensembl Protein ID ENSMLUP00000001215.2
UniProt Accession G1NVC4; G1NVC4_MYOLU
Genbank Protein ID ENSMLUP00000001215
Protein Name Coatomer subunit alpha
Genbank Nucleotide ID AAPE02033394
Gene Name COPA
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000001304.2 ENSMLUT00000001324.2 ENSMLUP00000001215.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.20e-36 121.8 133 163
UBD/Beta-Prp 3.10e-76 256.4 3 324
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH+  v c +f ++ +l+vs+s D t++vWD
   Q: 133  GHNHYVMCAQFhPSeDLVVSASLDQTVRVWD 163
           8***********666**************** PP
   

   UBD/Beta-Prp
   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           t +++++++++ + f+p++++++t+  +g i++wd+++ +l+ ++ +h+++v+ ++f+++++++v+g++D+ ikvw+++ + c+ tl g
   Q: 3    TKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLG 91
           67889999********************************************************************************* PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl............... 166
           h d+++++ f+ +  +++s+s+d+tirvw++++++c+  +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+               
   Q: 92   HLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVC-VLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDIsglrkknlspgaves 179
           **************************************.************************************************** PP
   S: 167  ............ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgs 241
                        t+ ++++  +gh++ v++ +f+++++ +vsg++d++vk+w + +++   v+t++gh +nv++  f+p++e+++s s
   Q: 180  dvrgitgvdlfgTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAweVDTCRGHYNNVSCAVFHPRQELILSNS 268
           ************888888888777********************************888888*************************** PP
   S: 242  sDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           +D+sir+Wd+ +++ ++t+ + +++++  a+ +++ n +++g  d+   ++kl++++p
   Q: 269  EDKSIRVWDMSKRTGVQTFRRDHDRFWVLAA-HPNLNLFAAG-HDGGMIVFKLERERP 324
           *******************************.5554444444.589999999988765 PP
   
Organism Myotis lucifugus
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.
Protein Sequence
(Fasta)
MLTKFETKSA RVKGLSFHPK RPWILTSLHN GVIQLWDYRM CTLIDKFDEH DGPVRGIDFH 60
KQQPLFVSGG DDYKIKVWNY KLRRCLFTLL GHLDYIRTTF FHHEYPWILS ASDDQTIRVW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067392|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCTGCAGGAT GCTAACCAAA TTCGAGACCA AGAGCGCGCG GGTCAAAGGT AGTGGAGCCG 60
GGGGGCTGGG TGTCGGGGCG GCGCTGTCAC GGGGGACAGC GGACCGACGT GTGGGCCCGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067392|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0030157--P:pancreatic juice secretion
GO:0016192--P:vesicle-mediated transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000064 Aegilops tauschii 53.68 0.00e+00 1323.00
IUUC-Aml-001758 Ailuropoda melanoleuca 97.00 0.00e+00 2454.00
IUUC-Atr-002493 Amborella trichopoda 54.18 0.00e+00 1313.00
IUUC-Apl-003385 Anas platyrhynchos 95.30 0.00e+00 2048.00
IUUC-Aca-005154 Anolis carolinensis 97.10 9.00e-122 428.00
IUUC-Aly-006020 Arabidopsis lyrata 61.57 0.00e+00 1094.00
IUUC-Ath-007058 Arabidopsis thaliana 53.84 0.00e+00 1312.00
IUUC-Ago-007992 Ashbya gossypii 44.53 0.00e+00 1021.00
IUUC-Acl-008027 Aspergillus clavatus 57.07 0.00e+00 1002.00
IUUC-Afl-008644 Aspergillus flavus 57.21 0.00e+00 1000.00
IUUC-Afu-008964 Aspergillus fumigatus 57.11 0.00e+00 1006.00
IUUC-Ani-009379 Aspergillus nidulans 56.47 0.00e+00 1008.00
IUUC-Ang-009756 Aspergillus niger 57.79 0.00e+00 1017.00
IUUC-Aor-010174 Aspergillus oryzae 57.21 0.00e+00 999.00
IUUC-Ate-010302 Aspergillus terreus 49.43 0.00e+00 1217.00
IUUC-Ame-011229 Astyanax mexicanus 86.13 0.00e+00 2190.00
IUUC-Bgr-012300 Blumeria graminis 48.24 0.00e+00 1129.00
IUUC-Bta-012524 Bos taurus 97.47 0.00e+00 2437.00
IUUC-Bci-013781 Botrytis cinerea 48.74 0.00e+00 1199.00
IUUC-Bdi-014549 Brachypodium distachyon 54.12 0.00e+00 1348.00
IUUC-Bol-015925 Brassica oleracea 61.48 0.00e+00 1081.00
IUUC-Bra-016978 Brassica rapa 60.79 0.00e+00 1075.00
IUUC-Cel-018115 Caenorhabditis elegans 64.11 0.00e+00 1123.00
IUUC-Cja-019107 Callithrix jacchus 95.14 0.00e+00 2374.00
IUUC-Cfa-020675 Canis familiaris 96.87 0.00e+00 2417.00
IUUC-Cpo-021813 Cavia porcellus 97.06 0.00e+00 2447.00
IUUC-Cre-022969 Chlamydomonas reinhardtii 64.41 0.00e+00 1108.00
IUUC-Csa-023523 Chlorocebus sabaeus 98.37 0.00e+00 2461.00
IUUC-Cho-024704 Choloepus hoffmanni 82.40 0.00e+00 1874.00
IUUC-Cin-025572 Ciona intestinalis 73.20 0.00e+00 1878.00
IUUC-Csv-025864 Ciona savignyi 75.12 0.00e+00 1293.00
IUUC-Cgl-026510 Colletotrichum gloeosporioides 57.21 0.00e+00 1019.00
IUUC-Cne-027053 Cryptococcus neoformans 51.90 0.00e+00 1243.00
IUUC-Cme-027222 Cyanidioschyzon merolae 39.65 1.00e-141 498.00
IUUC-Dre-027421 Danio rerio 86.23 0.00e+00 2202.00
IUUC-Dno-029303 Dasypus novemcinctus 96.91 0.00e+00 2444.00
IUUC-Dor-030290 Dipodomys ordii 96.64 0.00e+00 1078.00
IUUC-Dse-031543 Dothistroma septosporum 46.33 0.00e+00 1120.00
IUUC-Dme-031945 Drosophila melanogaster 69.52 0.00e+00 1706.00
IUUC-Ete-032873 Echinops telfairi 91.14 0.00e+00 2110.00
IUUC-Eca-033773 Equus caballus 95.20 0.00e+00 2383.00
IUUC-Eeu-034874 Erinaceus europaeus 84.93 0.00e+00 1489.00
IUUC-Fca-035739 Felis catus 96.43 0.00e+00 2372.00
IUUC-Fal-037263 Ficedula albicollis 87.55 0.00e+00 2123.00
IUUC-Fox-037738 Fusarium oxysporum 48.20 0.00e+00 1215.00
IUUC-Fso-038153 Fusarium solani 48.39 0.00e+00 1194.00
IUUC-Gmo-039602 Gadus morhua 81.51 0.00e+00 2061.00
IUUC-Ggr-039931 Gaeumannomyces graminis 56.31 0.00e+00 1012.00
IUUC-Gga-040590 Gallus gallus 96.17 0.00e+00 2408.00
IUUC-Gac-041318 Gasterosteus aculeatus 85.56 0.00e+00 2213.00
IUUC-Gma-043567 Glycine max 54.69 0.00e+00 1335.00
IUUC-Ggo-045029 Gorilla gorilla 97.49 0.00e+00 2449.00
IUUC-Hsa-046078 Homo sapiens 97.49 0.00e+00 2449.00
IUUC-Hvu-047556 Hordeum vulgare 55.13 0.00e+00 1362.00
IUUC-Itr-048881 Ictidomys tridecemlineatus 95.35 0.00e+00 1693.00
IUUC-Kpa-049256 Komagataella pastoris 45.67 0.00e+00 1084.00
IUUC-Lch-049706 Latimeria chalumnae 92.90 0.00e+00 2305.00
IUUC-Lpe-051316 Leersia perrieri 62.72 0.00e+00 1107.00
IUUC-Loc-051867 Lepisosteus oculatus 71.76 0.00e+00 1214.00
IUUC-Lma-053138 Leptosphaeria maculans 56.42 0.00e+00 1020.00
IUUC-Laf-053510 Loxodonta africana 97.80 0.00e+00 2465.00
IUUC-Mcc-055836 Macaca mulatta 97.24 0.00e+00 2441.00
IUUC-Meu-056238 Macropus eugenii 86.87 0.00e+00 1173.00
IUUC-Mor-057172 Magnaporthe oryzae 48.36 0.00e+00 1189.00
IUUC-Mpo-057300 Magnaporthe poae 48.80 0.00e+00 1181.00
IUUC-Mtr-058248 Medicago truncatula 55.22 0.00e+00 1365.00
IUUC-Mla-059019 Melampsora laricipopulina 52.61 0.00e+00 1292.00
IUUC-Mga-059499 Meleagris gallopavo 96.01 0.00e+00 2402.00
IUUC-Mvi-060336 Microbotryum violaceum 52.83 0.00e+00 1274.00
IUUC-Mmr-061102 Microcebus murinus 96.52 0.00e+00 2408.00
IUUC-Mdo-062594 Monodelphis domestica 97.39 0.00e+00 2466.00
IUUC-Mmu-063736 Mus musculus 95.87 0.00e+00 2429.00
IUUC-Mac-065398 Musa acuminata 52.31 0.00e+00 1243.00
IUUC-Mpu-066701 Mustela putorius furo 97.15 0.00e+00 2434.00
IUUC-Nfi-068270 Neosartorya fischeri 57.43 0.00e+00 1006.00
IUUC-Ncr-068892 Neurospora crassa 49.16 0.00e+00 1187.00
IUUC-Nle-069634 Nomascus leucogenys 98.94 0.00e+00 1373.00
IUUC-Opr-070952 Ochotona princeps 84.00 0.00e+00 1755.00
IUUC-Ont-072488 Oreochromis niloticus 87.10 0.00e+00 2224.00
IUUC-Ocu-074211 Oryctolagus cuniculus 97.31 0.00e+00 2454.00
IUUC-Oba-075761 Oryza barthii 62.60 0.00e+00 1105.00
IUUC-Obr-076429 Oryza brachyantha 62.60 0.00e+00 1105.00
IUUC-Ogl-077364 Oryza glaberrima 62.60 0.00e+00 1106.00
IUUC-Ogu-078257 Oryza glumaepatula 62.86 0.00e+00 1106.00
IUUC-Oin-079274 Oryza indica 62.49 0.00e+00 1105.00
IUUC-Olo-080466 Oryza longistaminata 62.52 0.00e+00 1090.00
IUUC-Ome-081993 Oryza meridionalis 64.62 0.00e+00 1029.00
IUUC-Oni-082874 Oryza nivara 62.86 0.00e+00 1105.00
IUUC-Opu-083885 Oryza punctata 53.82 0.00e+00 1328.00
IUUC-Oru-084274 Oryza rufipogon 62.60 0.00e+00 1106.00
IUUC-Osa-085565 Oryza sativa 62.60 0.00e+00 1106.00
IUUC-Ola-086921 Oryzias latipes 85.60 0.00e+00 2177.00
IUUC-Olu-087639 Ostreococcus lucimarinus 55.78 0.00e+00 1362.00
IUUC-Oga-087991 Otolemur garnettii 91.87 0.00e+00 2313.00
IUUC-Oar-089590 Ovis aries 97.55 0.00e+00 2461.00
IUUC-Ptr-090808 Pan troglodytes 97.57 0.00e+00 2450.00
IUUC-Pan-092475 Papio anubis 97.88 0.00e+00 2446.00
IUUC-Psi-093044 Pelodiscus sinensis 79.61 0.00e+00 1688.00
IUUC-Pno-094839 Phaeosphaeria nodorum 47.76 0.00e+00 1111.00
IUUC-Ppa-095254 Physcomitrella patens 56.55 0.00e+00 1406.00
IUUC-Pfo-097493 Poecilia formosa 87.02 0.00e+00 2185.00
IUUC-Pab-098497 Pongo abelii 98.37 0.00e+00 2462.00
IUUC-Pop-099992 Populus trichocarpa 56.46 0.00e+00 1346.00
IUUC-Pca-100413 Procavia capensis 89.15 0.00e+00 1007.00
IUUC-Ppe-101899 Prunus persica 54.58 0.00e+00 1331.00
IUUC-Pva-102126 Pteropus vampyrus 92.96 0.00e+00 2336.00
IUUC-Pgr-103376 Puccinia graminis 53.22 0.00e+00 1302.00
IUUC-Ptt-103978 Puccinia triticina 47.66 0.00e+00 1088.00
IUUC-Pte-104126 Pyrenophora teres 56.81 0.00e+00 979.00
IUUC-Pyt-104778 Pyrenophora triticirepentis 46.95 2.00e-178 619.00
IUUC-Rno-105428 Rattus norvegicus 96.66 0.00e+00 2440.00
IUUC-Sce-106464 Saccharomyces cerevisiae 43.75 0.00e+00 1008.00
IUUC-Sha-107301 Sarcophilus harrisii 97.69 0.00e+00 2427.00
IUUC-Sja-107961 Schizosaccharomyces japonicus 46.39 0.00e+00 1085.00
IUUC-Spo-108217 Schizosaccharomyces pombe 46.48 0.00e+00 1121.00
IUUC-Ssl-108643 Sclerotinia sclerotiorum 48.99 0.00e+00 1204.00
IUUC-Smo-109582 Selaginella moellendorffii 65.71 0.00e+00 1155.00
IUUC-Sit-109697 Setaria italica 62.13 0.00e+00 1098.00
IUUC-Sly-111759 Solanum lycopersicum 55.73 0.00e+00 1365.00
IUUC-Stu-112564 Solanum tuberosum 55.41 0.00e+00 1359.00
IUUC-Sar-113313 Sorex araneus 86.18 0.00e+00 1441.00
IUUC-Sbi-114388 Sorghum bicolor 62.72 0.00e+00 1105.00
IUUC-Sre-115209 Sporisorium reilianum 57.58 0.00e+00 1045.00
IUUC-Ssc-115933 Sus scrofa 97.80 0.00e+00 2465.00
IUUC-Tgu-117109 Taeniopygia guttata 80.81 0.00e+00 737.00
IUUC-Tru-117772 Takifugu rubripes 85.81 0.00e+00 2176.00
IUUC-Tsy-119105 Tarsius syrichta 83.64 0.00e+00 2081.00
IUUC-Tni-120556 Tetraodon nigroviridis 69.34 0.00e+00 1518.00
IUUC-Tca-121046 Theobroma cacao 54.31 0.00e+00 1362.00
IUUC-Tre-121951 Trichoderma reesei 57.04 0.00e+00 1016.00
IUUC-Tvi-122359 Trichoderma virens 57.31 0.00e+00 1023.00
IUUC-Tae-123688 Triticum aestivum 55.21 0.00e+00 1363.00
IUUC-Tur-126754 Triticum urartu 53.20 0.00e+00 1304.00
IUUC-Tme-127170 Tuber melanosporum 49.96 0.00e+00 1221.00
IUUC-Tbe-127882 Tupaia belangeri 93.12 0.00e+00 804.00
IUUC-Ttr-128217 Tursiops truncatus 94.90 0.00e+00 2384.00
IUUC-Uma-129337 Ustilago maydis 56.88 0.00e+00 1042.00
IUUC-Vda-129828 Verticillium dahliae 48.64 0.00e+00 1192.00
IUUC-Vpa-130537 Vicugna pacos 96.44 0.00e+00 2412.00
IUUC-Vvi-130958 Vitis vinifera 63.08 0.00e+00 1112.00
IUUC-Xtr-132857 Xenopus tropicalis 89.43 0.00e+00 2224.00
IUUC-Xma-133138 Xiphophorus maculatus 86.86 0.00e+00 2184.00
IUUC-Yli-134399 Yarrowia lipolytica 50.70 0.00e+00 865.00
IUUC-Zma-135612 Zea mays 54.21 0.00e+00 1344.00
Created Date 25-Jun-2017

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