iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016065.5	ENSGALT00000025882.5	ENSGALP00000025835.5
ENSGALG00000016065.5	ENSGALT00000082609.1	ENSGALP00000054341.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.80e-33	111.7	191	226
UBD/Beta-Prp	4.20e-53	180.8	335	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH +sv+c+af  + +++ +GsdD+ +k+W+++ g+
   Q: 191  GHLSSVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGR 226
           8**********955599**************98876 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
            + +fs  g +l+tgs+D++i+ +    +t++ +  l+ h d+v s++fs sgd+++sGs+d t+r+w  e+ ++ +            
   Q: 335  LCSSFSVGGMFLATGSTDHVIRMYyfGSETPERIAELESHADKVDSIQFSNSGDRFISGSRDGTARIWRFEEAEWRSIlldmsdrlpgd 423
           4667888899**************99999**********************************************9999********** PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtge 213
                ++  +  v+++++++d+n++v++ ++  +++W+++tg+ll++l g h d v  l+   fds  + ++s+++dg + +wd+ +g+
   Q: 424  mcsdEDKFMRPKVTMIAWNQDDNYVVTAVNNHLLKVWNSSTGQLLHDLVG-HADEVFVLEthpFDS--RIMLSAGHDGNIFIWDITKGT 509
           988877778889*************************************9.*********555555..99****************777 PP
   S: 214  c......vrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
                  + + +gh   v + +fsp++++++++ s+g + i+
   Q: 510  KtkhyfnMIEGQGH-GAVFDCKFSPDGQHFACTDSHGHLLIF 550
           63344433334444.566678999*********999998886 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MDYSRPRAPR LAHSRLSPSV SPAELYFLIA RFLSTGPCRG TLRVLVQELE QHQLLPKRLD 60
WEGNEHYRSY EELVLSNKHV APDHLLQICK RIGPILDKEI PPSISRVNSL LGAGRQSLLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGT CCTCGGCCTC CTTCGGCTCC GGCACGTCGC CGCCGCTCAT TGAGTCAGGT 60
AACGGCGGCG GGCCGCGGGC CGCTGCTCCC TGCCGCCATC TTCTCGAGGG CGGCGATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	30.91	7.00e-65	243.00
IUUC-Apl-004083	Anas platyrhynchos	82.01	0.00e+00	3124.00
IUUC-Aca-004348	Anolis carolinensis	65.54	0.00e+00	2169.00
IUUC-Aly-006517	Arabidopsis lyrata	30.69	2.00e-74	275.00
IUUC-Ame-010718	Astyanax mexicanus	70.71	0.00e+00	1185.00
IUUC-Bdi-014797	Brachypodium distachyon	29.59	3.00e-61	231.00
IUUC-Bra-017829	Brassica rapa	30.92	6.00e-72	266.00
IUUC-Cja-019966	Callithrix jacchus	66.45	0.00e+00	2372.00
IUUC-Cpo-021934	Cavia porcellus	75.62	0.00e+00	2268.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	34.26	2.00e-33	137.00
IUUC-Cho-024690	Choloepus hoffmanni	87.46	0.00e+00	700.00
IUUC-Dme-031752	Drosophila melanogaster	51.38	0.00e+00	686.00
IUUC-Fal-037307	Ficedula albicollis	83.33	0.00e+00	3298.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	76.02	0.00e+00	895.00
IUUC-Lch-049662	Latimeria chalumnae	63.60	0.00e+00	2047.00
IUUC-Lpe-051619	Leersia perrieri	30.39	1.00e-71	265.00
IUUC-Loc-052853	Lepisosteus oculatus	66.57	0.00e+00	1870.00
IUUC-Meu-056739	Macropus eugenii	73.80	0.00e+00	1066.00
IUUC-Mtr-058094	Medicago truncatula	30.30	4.00e-73	270.00
IUUC-Mga-060165	Meleagris gallopavo	97.41	0.00e+00	3312.00
IUUC-Mmr-061227	Microcebus murinus	69.30	0.00e+00	2360.00
IUUC-Mdo-062074	Monodelphis domestica	76.08	0.00e+00	2239.00
IUUC-Mmu-064075	Mus musculus	65.01	0.00e+00	2356.00
IUUC-Mac-065343	Musa acuminata	30.32	2.00e-75	278.00
IUUC-Ont-072298	Oreochromis niloticus	62.43	0.00e+00	1859.00
IUUC-Ocu-074456	Oryctolagus cuniculus	76.09	0.00e+00	2242.00
IUUC-Oba-075709	Oryza barthii	28.61	2.00e-62	234.00
IUUC-Opu-083233	Oryza punctata	29.54	1.00e-65	245.00
IUUC-Oru-085195	Oryza rufipogon	28.61	2.00e-62	234.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.77	2.00e-53	204.00
IUUC-Psi-093271	Pelodiscus sinensis	71.88	0.00e+00	2622.00
IUUC-Pma-094427	Petromyzon marinus	65.77	1.00e-130	458.00
IUUC-Ppa-095793	Physcomitrella patens	29.38	4.00e-73	270.00
IUUC-Pfo-097318	Poecilia formosa	59.05	0.00e+00	1811.00
IUUC-Pab-097573	Pongo abelii	76.25	0.00e+00	2222.00
IUUC-Pop-099672	Populus trichocarpa	30.68	7.00e-74	273.00
IUUC-Rno-105687	Rattus norvegicus	64.48	0.00e+00	2329.00
IUUC-Sha-106680	Sarcophilus harrisii	62.44	0.00e+00	2415.00
IUUC-Sit-110017	Setaria italica	31.80	6.00e-55	209.00
IUUC-Sbi-114195	Sorghum bicolor	28.80	4.00e-61	229.00
IUUC-Tgu-116513	Taeniopygia guttata	81.33	0.00e+00	3313.00
IUUC-Tsy-118921	Tarsius syrichta	74.34	0.00e+00	1718.00
IUUC-Tca-121615	Theobroma cacao	30.45	2.00e-68	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence