iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Vvi-130834

UUCD1 version

UUC-ViV-00606

Ensembl Protein ID

VIT_19s0085g00630.t01

UniProt Accession

F6H9U8; F6H9U8_VITVI

Genbank Protein ID

CCB48991.1

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

FN595503

Gene Name

VIT_19s0085g00630

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VIT_19s0085g00630	VIT_19s0085g00630.t01	VIT_19s0085g00630.t01

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	9.10e-84	280.8	55	241
UBD/Alpha-Helix/UBA	5.10e-06	27.0	10	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselk 89
           ++++leel++rYkdp+ d+i ++g++ +c+dl+vdp+di++Lv++w+++aat+cefs++ef++gl+alg+ds+ek++e+++++++elk
   Q: 55   DSRHLEELYSRYKDPYVDMIMADGISVLCNDLQVDPQDIVMLVVSWHMKAATMCEFSKQEFISGLQALGIDSLEKFRERIQFMRTELK 142
           6899************************************************************************************ PP
   S: 90   deqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           deqkf++iY+faf +ak+kgqksl+ldtai +w+Ll+ae+++ l+d+w++fL+ +++k+is+DtW +lLef+k++++ lsnYd+egaW
   Q: 143  DEQKFREIYNFAFGWAKEKGQKSLALDTAIGMWQLLFAEKQWALVDHWCQFLQARHNKAISRDTWSQLLEFAKTVDPSLSNYDAEGAW 230
           **************************************************************************************** PP
   S: 178  PvliDefveyl 188
           P+liDefveyl
   Q: 231  PYLIDEFVEYL 241
           *********97 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q+++ +G +++ al aL a++++le A + +++
   Q: 10   DKVQQFMAiTGASEKVALHALKASDWHLEGAFDVFYS 46
           89*****************************998876 PP

Organism

Vitis vinifera

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLGRGHRD KVQQFMAITG ASEKVALHAL KASDWHLEGA FDVFYSQPQI KAFTDSRHLE 60
ELYSRYKDPY VDMIMADGIS VLCNDLQVDP QDIVMLVVSW HMKAATMCEF SKQEFISGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCAAAAAA ATAGTGTGTT CTAGAGAGAG AAAAACCCGG AAACCCTAGT TTCTCTCTCT 60
AGAATTTCTC ACACAACCCA TCAACCATCT CTCATATATT CGGTTTCCTT CTCCAAATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	76.89	2.00e-119	421.00
IUUC-Aml-001879	Ailuropoda melanoleuca	44.31	6.00e-60	223.00
IUUC-Atr-002697	Amborella trichopoda	90.09	4.00e-57	211.00
IUUC-Apl-003933	Anas platyrhynchos	44.72	3.00e-60	224.00
IUUC-Aca-005269	Anolis carolinensis	42.91	2.00e-58	218.00
IUUC-Aly-006285	Arabidopsis lyrata	68.67	2.00e-98	350.00
IUUC-Ath-007531	Arabidopsis thaliana	77.60	5.00e-118	416.00
IUUC-Ago-007806	Ashbya gossypii	27.20	4.00e-19	87.40
IUUC-Acl-008172	Aspergillus clavatus	26.59	2.00e-23	102.00
IUUC-Afl-008569	Aspergillus flavus	28.92	7.00e-30	123.00
IUUC-Afu-009005	Aspergillus fumigatus	27.06	8.00e-19	85.90
IUUC-Ani-009241	Aspergillus nidulans	22.15	8.00e-20	90.10
IUUC-Ang-009664	Aspergillus niger	28.12	4.00e-26	110.00
IUUC-Aor-009902	Aspergillus oryzae	29.25	4.00e-11	59.30
IUUC-Ate-010414	Aspergillus terreus	27.09	9.00e-28	115.00
IUUC-Ame-011763	Astyanax mexicanus	45.12	3.00e-61	227.00
IUUC-Bgr-011991	Blumeria graminis	32.99	8.00e-21	93.20
IUUC-Bta-013561	Bos taurus	44.40	9.00e-56	209.00
IUUC-Bci-013824	Botrytis cinerea	33.47	4.00e-31	127.00
IUUC-Bdi-014138	Brachypodium distachyon	74.70	1.00e-115	408.00
IUUC-Bol-015564	Brassica oleracea	77.11	4.00e-118	416.00
IUUC-Bra-017111	Brassica rapa	77.51	1.00e-118	418.00
IUUC-Cel-018441	Caenorhabditis elegans	34.18	1.00e-41	162.00
IUUC-Cja-018854	Callithrix jacchus	44.31	2.00e-60	224.00
IUUC-Cfa-020523	Canis familiaris	43.97	2.00e-55	207.00
IUUC-Cpo-021832	Cavia porcellus	43.95	2.00e-59	221.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	45.31	8.00e-64	236.00
IUUC-Csa-023551	Chlorocebus sabaeus	44.53	1.00e-60	224.00
IUUC-Cho-024373	Choloepus hoffmanni	43.90	5.00e-56	209.00
IUUC-Cin-025269	Ciona intestinalis	42.11	2.00e-59	221.00
IUUC-Csv-025976	Ciona savignyi	33.93	8.00e-35	139.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	32.56	1.00e-21	95.10
IUUC-Cne-026950	Cryptococcus neoformans	35.32	2.00e-35	142.00
IUUC-Cme-027199	Cyanidioschyzon merolae	29.92	3.00e-09	55.10
IUUC-Dre-028247	Danio rerio	45.12	3.00e-61	227.00
IUUC-Dno-028974	Dasypus novemcinctus	44.53	1.00e-60	224.00
IUUC-Dor-030143	Dipodomys ordii	44.72	6.00e-61	226.00
IUUC-Dse-031365	Dothistroma septosporum	27.82	5.00e-25	107.00
IUUC-Dme-032197	Drosophila melanogaster	40.16	3.00e-56	211.00
IUUC-Ete-032371	Echinops telfairi	44.31	6.00e-60	223.00
IUUC-Eca-033242	Equus caballus	44.31	6.00e-60	223.00
IUUC-Eeu-035317	Erinaceus europaeus	43.90	1.00e-59	221.00
IUUC-Fca-036061	Felis catus	44.13	4.00e-60	223.00
IUUC-Fal-036715	Ficedula albicollis	44.72	2.00e-60	224.00
IUUC-Fox-037884	Fusarium oxysporum	27.93	8.00e-15	72.40
IUUC-Fso-038150	Fusarium solani	28.57	1.00e-16	79.30
IUUC-Gmo-038750	Gadus morhua	45.12	3.00e-60	224.00
IUUC-Ggr-039959	Gaeumannomyces graminis	29.02	1.00e-16	80.50
IUUC-Gga-040935	Gallus gallus	44.13	4.00e-60	223.00
IUUC-Gac-041478	Gasterosteus aculeatus	44.31	1.00e-59	222.00
IUUC-Gma-043545	Glycine max	86.49	3.00e-135	473.00
IUUC-Ggo-044972	Gorilla gorilla	44.13	2.00e-60	224.00
IUUC-Hsa-046994	Homo sapiens	44.13	8.00e-61	225.00
IUUC-Hvu-047636	Hordeum vulgare	36.00	7.00e-21	92.40
IUUC-Itr-047902	Ictidomys tridecemlineatus	44.72	7.00e-60	222.00
IUUC-Kpa-049127	Komagataella pastoris	28.29	7.00e-27	113.00
IUUC-Lch-049751	Latimeria chalumnae	44.53	2.00e-60	224.00
IUUC-Lpe-051540	Leersia perrieri	78.14	4.00e-120	422.00
IUUC-Loc-052509	Lepisosteus oculatus	44.94	5.00e-61	226.00
IUUC-Lma-053103	Leptosphaeria maculans	28.57	1.00e-26	112.00
IUUC-Laf-053972	Loxodonta africana	45.12	6.00e-61	226.00
IUUC-Mcc-054700	Macaca mulatta	44.13	1.00e-60	225.00
IUUC-Meu-056791	Macropus eugenii	36.72	6.00e-44	169.00
IUUC-Mor-056909	Magnaporthe oryzae	28.36	4.00e-24	103.00
IUUC-Mpo-057299	Magnaporthe poae	28.15	1.00e-20	92.80
IUUC-Mtr-057964	Medicago truncatula	84.17	1.00e-133	468.00
IUUC-Mla-058990	Melampsora laricipopulina	25.37	4.00e-15	74.70
IUUC-Mga-060072	Meleagris gallopavo	45.12	2.00e-60	224.00
IUUC-Mvi-060312	Microbotryum violaceum	35.08	2.00e-39	154.00
IUUC-Mmr-060851	Microcebus murinus	44.31	1.00e-59	221.00
IUUC-Mdo-063074	Monodelphis domestica	44.31	3.00e-59	223.00
IUUC-Mmu-063816	Mus musculus	45.75	1.00e-62	231.00
IUUC-Mac-065016	Musa acuminata	85.25	5.00e-95	338.00
IUUC-Mpu-066870	Mustela putorius furo	43.97	2.00e-55	207.00
IUUC-Mlu-067701	Myotis lucifugus	43.90	7.00e-59	219.00
IUUC-Nfi-068610	Neosartorya fischeri	27.65	6.00e-19	85.90
IUUC-Ncr-068780	Neurospora crassa	24.63	1.00e-18	86.30
IUUC-Nle-069291	Nomascus leucogenys	44.53	1.00e-60	224.00
IUUC-Opr-070682	Ochotona princeps	42.02	5.00e-43	167.00
IUUC-Ont-071813	Oreochromis niloticus	44.31	2.00e-60	224.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.90	2.00e-59	221.00
IUUC-Ocu-074648	Oryctolagus cuniculus	44.31	6.00e-60	223.00
IUUC-Oba-074993	Oryza barthii	78.23	7.00e-121	425.00
IUUC-Obr-076341	Oryza brachyantha	76.21	2.00e-118	417.00
IUUC-Ogl-077099	Oryza glaberrima	78.23	7.00e-121	425.00
IUUC-Ogu-078285	Oryza glumaepatula	78.63	2.00e-121	427.00
IUUC-Oin-079441	Oryza indica	78.63	2.00e-121	426.00
IUUC-Olo-081037	Oryza longistaminata	78.63	2.00e-121	426.00
IUUC-Ome-081357	Oryza meridionalis	78.63	2.00e-121	426.00
IUUC-Oni-082632	Oryza nivara	78.23	1.00e-120	424.00
IUUC-Opu-083351	Oryza punctata	77.68	1.00e-112	397.00
IUUC-Oru-084306	Oryza rufipogon	78.63	2.00e-121	426.00
IUUC-Osa-085307	Oryza sativa	78.63	2.00e-121	426.00
IUUC-Ola-086371	Oryzias latipes	44.72	8.00e-61	225.00
IUUC-Olu-087646	Ostreococcus lucimarinus	43.09	7.00e-54	202.00
IUUC-Oga-088621	Otolemur garnettii	44.72	2.00e-60	224.00
IUUC-Oar-090405	Ovis aries	44.72	3.00e-60	224.00
IUUC-Ptr-090735	Pan troglodytes	44.31	6.00e-60	223.00
IUUC-Pan-092825	Papio anubis	44.13	8.00e-61	225.00
IUUC-Psi-093110	Pelodiscus sinensis	43.53	2.00e-54	204.00
IUUC-Pma-094196	Petromyzon marinus	39.78	2.00e-41	161.00
IUUC-Pno-095145	Phaeosphaeria nodorum	30.19	1.00e-22	99.00
IUUC-Ppa-095306	Physcomitrella patens	74.60	7.00e-116	408.00
IUUC-Pfo-097121	Poecilia formosa	43.50	1.00e-60	225.00
IUUC-Pab-098197	Pongo abelii	43.10	9.00e-55	205.00
IUUC-Pop-098821	Populus trichocarpa	89.43	2.00e-64	236.00
IUUC-Pca-100218	Procavia capensis	42.68	2.00e-58	217.00
IUUC-Ppe-102032	Prunus persica	87.60	1.00e-133	467.00
IUUC-Pva-102691	Pteropus vampyrus	44.53	9.00e-61	225.00
IUUC-Pgr-103633	Puccinia graminis	27.49	7.00e-22	96.70
IUUC-Ptt-103979	Puccinia triticina	33.33	1.00e-04	39.70
IUUC-Pyt-104428	Pyrenophora triticirepentis	25.24	4.00e-20	90.50
IUUC-Rno-105016	Rattus norvegicus	46.15	1.00e-62	232.00
IUUC-Sce-106358	Saccharomyces cerevisiae	25.19	1.00e-20	92.80
IUUC-Sha-106888	Sarcophilus harrisii	44.31	6.00e-60	223.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	28.87	3.00e-21	94.40
IUUC-Spo-108207	Schizosaccharomyces pombe	35.91	3.00e-25	107.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	32.70	8.00e-32	129.00
IUUC-Smo-108750	Selaginella moellendorffii	68.03	7.00e-97	345.00
IUUC-Sit-110052	Setaria italica	77.29	1.00e-121	427.00
IUUC-Sly-111489	Solanum lycopersicum	82.88	4.00e-130	456.00
IUUC-Stu-112517	Solanum tuberosum	65.46	2.00e-100	357.00
IUUC-Sar-113509	Sorex araneus	44.19	8.00e-40	155.00
IUUC-Sbi-114113	Sorghum bicolor	78.23	3.00e-121	426.00
IUUC-Sre-115221	Sporisorium reilianum	26.30	6.00e-25	107.00
IUUC-Ssc-115547	Sus scrofa	44.53	1.00e-60	224.00
IUUC-Tgu-117196	Taeniopygia guttata	45.12	2.00e-60	224.00
IUUC-Tru-117740	Takifugu rubripes	45.31	4.00e-61	226.00
IUUC-Tsy-119599	Tarsius syrichta	44.31	5.00e-60	223.00
IUUC-Tni-120542	Tetraodon nigroviridis	43.31	3.00e-59	220.00
IUUC-Tca-121033	Theobroma cacao	89.96	1.00e-142	497.00
IUUC-Tre-121986	Trichoderma reesei	25.51	2.00e-20	91.70
IUUC-Tvi-122607	Trichoderma virens	31.03	5.00e-27	113.00
IUUC-Tae-125740	Triticum aestivum	66.10	6.00e-114	402.00
IUUC-Tur-126375	Triticum urartu	59.81	3.00e-109	387.00
IUUC-Tme-126878	Tuber melanosporum	31.58	6.00e-35	140.00
IUUC-Tbe-127429	Tupaia belangeri	42.02	5.00e-43	167.00
IUUC-Ttr-129086	Tursiops truncatus	40.65	2.00e-51	194.00
IUUC-Uma-129364	Ustilago maydis	27.76	8.00e-31	126.00
IUUC-Vda-129929	Verticillium dahliae	32.09	1.00e-20	93.20
IUUC-Vpa-130048	Vicugna pacos	38.21	5.00e-46	176.00
IUUC-Xtr-131888	Xenopus tropicalis	43.50	1.00e-59	222.00
IUUC-Xma-134122	Xiphophorus maculatus	43.90	3.00e-61	227.00
IUUC-Yli-134595	Yarrowia lipolytica	31.78	2.00e-33	134.00
IUUC-Zma-135642	Zea mays	76.31	6.00e-119	419.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence