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Tag Content
iUUCD ID IUUC-Pno-094927
Ensembl Protein ID SNOT_07799
UniProt Accession Q0UKB5; NACA_PHANO
Genbank Protein ID EAT85265.1
Protein Name Nascent polypeptide-associated complex subunit alpha; Alpha-NAC
Genbank Nucleotide ID CH445335
Gene Name EGD2; SNOG_07799
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SNOG_07799 SNOT_07799 SNOT_07799
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 48.61 2.00e-15 77.40 IUUC-Sce-106371
UBD/Alpha-Helix/UBA 52.70 2.00e-18 86.70 IUUC-Spo-108121
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Phaeosphaeria nodorum
Functional Description
(View)

Functional Description



     Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation (By similarity).
Protein Sequence
(Fasta)
MSNPRIEELP DEPEKKNVQI EEDESSDESE GEEGEANIPA GASVAVHSRN EKKARKAIAK 60
LGLKHIDGIT RVTLRRPKNI LFVINQPDVY KSPSSNTWII FGEAKIEDLN SQAQASAAQQ 120
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Protein Fasta Sequence



>IUUC-Pno-094927|UBD,UBA|Phaeosphaeria nodorum
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Nucleotide Sequence
(Fasta)
ATGTCCAACC CACGCATTGA AGAGCTCCCC GACGAGCCCG AGAAGAAGAA CGTCCAGATC 60
GAGGAGGATG AGTCCAGCGA CGAGTCCGAG GGCGAGGAGG GCGAGGCCAA CATCCCCGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Pno-094927|UBD,UBA|Phaeosphaeria nodorum
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport

Interpro

IPR016641--EGD2/NACA
IPR002715--Nas_poly-pep-assoc_cplx_dom

PROSITE

PS51151--NAC_AB

Pfam

PF01849--NAC

SMART

SM01407--NAC

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0015031--P:protein transport

KEGG pno:SNOG_07799
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001167 Aegilops tauschii 65.38 2.00e-18 83.60
IUUC-Aml-002185 Ailuropoda melanoleuca 49.70 2.00e-28 120.00
IUUC-Atr-002586 Amborella trichopoda 44.12 1.00e-11 61.20
IUUC-Apl-003190 Anas platyrhynchos 64.29 2.00e-22 96.70
IUUC-Aca-005265 Anolis carolinensis 72.97 7.00e-10 55.10
IUUC-Aly-006397 Arabidopsis lyrata 64.81 7.00e-19 84.70
IUUC-Ath-007378 Arabidopsis thaliana 61.54 4.00e-17 79.70
IUUC-Ago-007936 Ashbya gossypii 45.95 2.00e-17 79.70
IUUC-Acl-008036 Aspergillus clavatus 71.30 9.00e-37 144.00
IUUC-Afl-008462 Aspergillus flavus 72.73 2.00e-39 153.00
IUUC-Afu-008832 Aspergillus fumigatus 70.37 2.00e-33 133.00
IUUC-Ani-009246 Aspergillus nidulans 72.07 5.00e-39 152.00
IUUC-Ang-009808 Aspergillus niger 71.30 4.00e-37 145.00
IUUC-Aor-009972 Aspergillus oryzae 72.73 2.00e-39 153.00
IUUC-Ame-011674 Astyanax mexicanus 69.12 8.00e-26 108.00
IUUC-Bgr-012162 Blumeria graminis 58.29 3.00e-43 166.00
IUUC-Bta-012508 Bos taurus 72.97 8.00e-10 55.10
IUUC-Bci-013643 Botrytis cinerea 70.18 2.00e-35 140.00
IUUC-Bdi-014874 Brachypodium distachyon 65.38 3.00e-18 83.20
IUUC-Bol-015681 Brassica oleracea 62.96 2.00e-18 83.20
IUUC-Bra-017630 Brassica rapa 62.96 3.00e-18 83.20
IUUC-Cel-018111 Caenorhabditis elegans 68.18 4.00e-24 102.00
IUUC-Cja-019846 Callithrix jacchus 44.94 3.00e-29 122.00
IUUC-Cfa-020429 Canis familiaris 72.97 8.00e-10 55.10
IUUC-Cpo-021659 Cavia porcellus 45.51 7.00e-29 121.00
IUUC-Cre-022679 Chlamydomonas reinhardtii 67.19 1.00e-23 100.00
IUUC-Csa-023260 Chlorocebus sabaeus 48.50 1.00e-28 120.00
IUUC-Cho-024869 Choloepus hoffmanni 72.97 9.00e-10 54.70
IUUC-Cin-025166 Ciona intestinalis 78.38 3.00e-11 59.70
IUUC-Csv-026284 Ciona savignyi 69.81 3.00e-20 88.60
IUUC-Cgl-026520 Colletotrichum gloeosporioides 65.77 2.00e-33 133.00
IUUC-Cne-026920 Cryptococcus neoformans 63.01 2.00e-25 107.00
IUUC-Cme-027301 Cyanidioschyzon merolae 56.45 7.00e-19 85.50
IUUC-Dre-028709 Danio rerio 72.97 1.00e-09 57.00
IUUC-Dno-029786 Dasypus novemcinctus 72.97 9.00e-10 58.20
IUUC-Dor-030962 Dipodomys ordii 72.97 8.00e-10 55.10
IUUC-Dme-032061 Drosophila melanogaster 69.12 1.00e-23 101.00
IUUC-Ete-032965 Echinops telfairi 70.27 2.00e-09 53.90
IUUC-Eca-034049 Equus caballus 72.97 7.00e-10 55.50
IUUC-Eeu-034673 Erinaceus europaeus 72.97 7.00e-10 55.10
IUUC-Fca-035429 Felis catus 49.10 1.00e-28 120.00
IUUC-Fal-037006 Ficedula albicollis 69.12 1.00e-25 107.00
IUUC-Fox-037704 Fusarium oxysporum 68.75 3.00e-33 132.00
IUUC-Fso-038247 Fusarium solani 66.67 2.00e-34 136.00
IUUC-Gmo-039002 Gadus morhua 65.62 2.00e-22 97.40
IUUC-Ggr-039888 Gaeumannomyces graminis 66.36 3.00e-35 139.00
IUUC-Gga-040237 Gallus gallus 72.97 8.00e-10 55.10
IUUC-Gac-041800 Gasterosteus aculeatus 72.97 1.00e-09 56.20
IUUC-Gma-043275 Glycine max 58.54 1.00e-07 48.10
IUUC-Ggo-045163 Gorilla gorilla 60.00 2.00e-24 103.00
IUUC-Hsa-045795 Homo sapiens 72.97 1.00e-09 58.50
IUUC-Hvu-047376 Hordeum vulgare 65.38 3.00e-18 83.20
IUUC-Itr-048152 Ictidomys tridecemlineatus 72.97 7.00e-10 55.10
IUUC-Kpa-049166 Komagataella pastoris 52.05 9.00e-19 84.70
IUUC-Lch-050076 Latimeria chalumnae 72.97 5.00e-10 55.80
IUUC-Lpe-051258 Leersia perrieri 64.81 1.00e-19 87.40
IUUC-Loc-052292 Lepisosteus oculatus 78.79 4.00e-09 53.10
IUUC-Lma-053293 Leptosphaeria maculans 94.55 2.00e-48 183.00
IUUC-Laf-054393 Loxodonta africana 65.15 3.00e-24 102.00
IUUC-Mcc-054632 Macaca mulatta 72.97 1.00e-09 58.20
IUUC-Meu-056242 Macropus eugenii 69.12 5.00e-26 108.00
IUUC-Mor-057099 Magnaporthe oryzae 67.27 7.00e-37 144.00
IUUC-Mpo-057543 Magnaporthe poae 64.76 2.00e-28 116.00
IUUC-Mtr-058769 Medicago truncatula 67.31 2.00e-18 83.60
IUUC-Mla-059166 Melampsora laricipopulina 49.23 5.00e-14 68.60
IUUC-Mga-059406 Meleagris gallopavo 72.97 8.00e-10 55.10
IUUC-Mvi-060390 Microbotryum violaceum 51.56 4.00e-16 75.50
IUUC-Mmr-061475 Microcebus murinus 50.30 4.00e-29 122.00
IUUC-Mdo-062077 Monodelphis domestica 72.97 7.00e-10 57.40
IUUC-Mmu-063984 Mus musculus 72.97 1.00e-09 58.50
IUUC-Mac-065175 Musa acuminata 64.81 7.00e-19 85.10
IUUC-Mpu-066751 Mustela putorius furo 47.78 4.00e-29 122.00
IUUC-Mlu-068234 Myotis lucifugus 72.97 7.00e-10 55.10
IUUC-Nfi-068541 Neosartorya fischeri 70.37 2.00e-33 133.00
IUUC-Ncr-068830 Neurospora crassa 65.77 5.00e-34 135.00
IUUC-Nle-069126 Nomascus leucogenys 72.97 8.00e-10 55.50
IUUC-Opr-070742 Ochotona princeps 72.97 7.00e-10 55.50
IUUC-Ont-071828 Oreochromis niloticus 69.12 3.00e-25 106.00
IUUC-Oan-073462 Ornithorhynchus anatinus 78.79 5.00e-09 55.80
IUUC-Ocu-074890 Oryctolagus cuniculus 45.51 5.00e-28 119.00
IUUC-Oba-075995 Oryza barthii 64.81 8.00e-20 88.20
IUUC-Obr-076073 Oryza brachyantha 64.81 1.00e-19 87.40
IUUC-Ogl-077445 Oryza glaberrima 64.81 8.00e-20 88.20
IUUC-Ogu-078606 Oryza glumaepatula 64.81 8.00e-20 88.20
IUUC-Oin-079287 Oryza indica 64.81 8.00e-20 88.20
IUUC-Olo-080686 Oryza longistaminata 47.95 3.00e-15 73.20
IUUC-Ome-081567 Oryza meridionalis 64.81 3.00e-19 85.90
IUUC-Oni-082873 Oryza nivara 64.81 8.00e-20 88.20
IUUC-Opu-083488 Oryza punctata 64.81 2.00e-19 87.00
IUUC-Oru-084592 Oryza rufipogon 64.81 8.00e-20 88.20
IUUC-Osa-086102 Oryza sativa 64.81 9.00e-20 88.20
IUUC-Ola-087531 Oryzias latipes 72.97 5.00e-10 55.80
IUUC-Olu-087895 Ostreococcus lucimarinus 55.77 1.00e-15 73.20
IUUC-Oga-088239 Otolemur garnettii 72.97 7.00e-10 55.10
IUUC-Oar-090371 Ovis aries 50.30 5.00e-29 122.00
IUUC-Ptr-090481 Pan troglodytes 44.31 4.00e-26 112.00
IUUC-Pan-092210 Papio anubis 48.50 3.00e-28 119.00
IUUC-Psi-093588 Pelodiscus sinensis 72.97 7.00e-10 55.10
IUUC-Pma-094702 Petromyzon marinus 69.12 1.00e-25 107.00
IUUC-Ppa-095389 Physcomitrella patens 66.13 3.00e-21 92.80
IUUC-Pfo-096744 Poecilia formosa 69.12 1.00e-25 107.00
IUUC-Pab-098044 Pongo abelii 72.97 7.00e-10 55.10
IUUC-Pop-099938 Populus trichocarpa 64.81 4.00e-19 85.90
IUUC-Pca-100355 Procavia capensis 46.11 1.00e-27 117.00
IUUC-Ppe-101786 Prunus persica 64.81 8.00e-19 85.10
IUUC-Pva-102494 Pteropus vampyrus 69.12 7.00e-26 108.00
IUUC-Pgr-103303 Puccinia graminis 58.46 2.00e-18 83.60
IUUC-Ptt-103748 Puccinia triticina 56.82 3.00e-10 56.60
IUUC-Pte-104368 Pyrenophora teres 95.45 4.00e-49 185.00
IUUC-Pyt-104542 Pyrenophora triticirepentis 93.64 9.00e-49 184.00
IUUC-Rno-105387 Rattus norvegicus 72.97 1.00e-09 58.20
IUUC-Sce-106371 Saccharomyces cerevisiae 48.61 1.00e-16 77.40
IUUC-Sha-107189 Sarcophilus harrisii 72.97 7.00e-10 55.10
IUUC-Sja-107942 Schizosaccharomyces japonicus 51.39 2.00e-17 80.10
IUUC-Spo-108121 Schizosaccharomyces pombe 66.67 1.00e-11 60.80
IUUC-Ssl-108595 Sclerotinia sclerotiorum 71.05 1.00e-36 144.00
IUUC-Smo-108783 Selaginella moellendorffii 66.67 1.00e-18 84.30
IUUC-Sit-110180 Setaria italica 64.81 8.00e-19 85.10
IUUC-Sly-110957 Solanum lycopersicum 65.38 1.00e-17 81.30
IUUC-Stu-112873 Solanum tuberosum 63.46 8.00e-17 78.20
IUUC-Sar-113668 Sorex araneus 72.97 7.00e-10 55.50
IUUC-Sbi-114223 Sorghum bicolor 65.38 2.00e-18 84.00
IUUC-Sre-115220 Sporisorium reilianum 47.57 4.00e-20 89.40
IUUC-Ssc-116119 Sus scrofa 72.97 7.00e-10 55.10
IUUC-Tgu-116528 Taeniopygia guttata 69.12 9.00e-26 107.00
IUUC-Tru-117538 Takifugu rubripes 70.27 1.00e-09 54.70
IUUC-Tsy-118855 Tarsius syrichta 72.97 9.00e-10 54.70
IUUC-Tni-120134 Tetraodon nigroviridis 72.97 5.00e-10 55.80
IUUC-Tca-121524 Theobroma cacao 62.96 1.00e-18 84.30
IUUC-Tre-121915 Trichoderma reesei 60.53 3.00e-30 123.00
IUUC-Tvi-122411 Trichoderma virens 59.63 6.00e-28 115.00
IUUC-Tae-124851 Triticum aestivum 65.38 2.00e-18 83.20
IUUC-Tur-126821 Triticum urartu 65.38 3.00e-18 82.40
IUUC-Tme-126875 Tuber melanosporum 74.55 3.00e-35 139.00
IUUC-Tbe-127759 Tupaia belangeri 67.57 2.00e-08 50.40
IUUC-Ttr-129124 Tursiops truncatus 49.69 1.00e-27 117.00
IUUC-Uma-129551 Ustilago maydis 45.71 5.00e-21 92.00
IUUC-Vda-129992 Verticillium dahliae 67.57 6.00e-33 131.00
IUUC-Vpa-130096 Vicugna pacos 72.97 6.00e-10 55.50
IUUC-Vvi-130940 Vitis vinifera 63.46 3.00e-17 79.70
IUUC-Xtr-132454 Xenopus tropicalis 72.97 1.00e-09 54.70
IUUC-Xma-133842 Xiphophorus maculatus 69.12 2.00e-25 107.00
IUUC-Yli-134485 Yarrowia lipolytica 47.76 6.00e-16 75.50
IUUC-Zma-135748 Zea mays 64.81 8.00e-19 84.70
Created Date 25-Jun-2017

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