iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000013125.2	ENSCJAT00000025521.2	ENSCJAP00000024127.2
ENSCJAG00000013125.2	ENSCJAT00000025531.1	ENSCJAP00000024137.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.80e-06	27.3	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ +  Cl +w     + s +++CP Cr
   Q: 351  CKICAESNKD-VKIEPCGHLLCSRCLAAW-----QHSDSQTCPFCR 390
           99********.******************.....6889999****8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAVALAPRGR QWEKARAFDR AVRLLQRLEE QCSDPRLSMS PPSLRDLLPR TAQLLQEVAQ 60
ARRAAGGGDP GDPGGSENFL VIYLANLEAK SKQVAELLPP RGPRSANDEL FREGSRLRRQ 120

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Nucleotide Sequence
(Fasta)

CTCTAGGGCC CGCCCTCTCC TTTCACTCTG GGCGAGGCCG CGCCTATTCC GGCGGCACTC 60
GGGATTCTCC CATGGCTGTG GCGTTGGCCC CGCGGGGGCG ACAGTGGGAA AAGGCCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cjc:100400634

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	79.26	0.00e+00	642.00
IUUC-Bta-012705	Bos taurus	81.72	0.00e+00	684.00
IUUC-Cfa-020593	Canis familiaris	76.83	1.00e-177	615.00
IUUC-Cpo-021289	Cavia porcellus	75.76	3.00e-179	620.00
IUUC-Csa-023966	Chlorocebus sabaeus	88.30	0.00e+00	731.00
IUUC-Dor-030246	Dipodomys ordii	74.75	1.00e-123	436.00
IUUC-Eca-033921	Equus caballus	71.20	7.00e-152	530.00
IUUC-Fca-035747	Felis catus	65.16	9.00e-156	543.00
IUUC-Fox-037671	Fusarium oxysporum	46.88	4.00e-05	41.60
IUUC-Ggo-044622	Gorilla gorilla	92.72	0.00e+00	657.00
IUUC-Hsa-045735	Homo sapiens	89.87	0.00e+00	806.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	80.58	3.00e-174	604.00
IUUC-Laf-053983	Loxodonta africana	77.80	0.00e+00	683.00
IUUC-Mtr-058038	Medicago truncatula	30.93	3.00e-09	55.50
IUUC-Mmr-061310	Microcebus murinus	80.92	0.00e+00	655.00
IUUC-Mmu-064155	Mus musculus	73.83	0.00e+00	662.00
IUUC-Mpu-066655	Mustela putorius furo	80.53	0.00e+00	641.00
IUUC-Mlu-067929	Myotis lucifugus	81.91	8.00e-151	525.00
IUUC-Nle-070065	Nomascus leucogenys	75.95	0.00e+00	654.00
IUUC-Ocu-074049	Oryctolagus cuniculus	76.01	2.00e-132	464.00
IUUC-Oga-087952	Otolemur garnettii	80.08	0.00e+00	721.00
IUUC-Oar-089382	Ovis aries	79.77	0.00e+00	648.00
IUUC-Ptr-090579	Pan troglodytes	65.61	5.00e-151	526.00
IUUC-Pan-092075	Papio anubis	88.40	0.00e+00	765.00
IUUC-Pab-098100	Pongo abelii	80.38	0.00e+00	701.00
IUUC-Pca-100830	Procavia capensis	77.87	5.00e-109	387.00
IUUC-Pva-102714	Pteropus vampyrus	77.78	3.00e-165	574.00
IUUC-Rno-105348	Rattus norvegicus	76.07	0.00e+00	669.00
IUUC-Ssc-116424	Sus scrofa	78.59	0.00e+00	678.00
IUUC-Ttr-128807	Tursiops truncatus	86.59	9.00e-140	489.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence