iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058110

Ensembl Protein ID

AES92586

UniProt Accession

G7JHZ9; G7JHZ9_MEDTR

Genbank Protein ID

AES92586.1

Protein Name

NEDD8-activating enzyme E1 catalytic subunit

Genbank Nucleotide ID

CM001220

Gene Name

MTR_4g131690

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_4g131690	AES92586	AES92586

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.10e-88	298.2	48	235

Active Site

Position(s)	Description	Evidence
216	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 19   akvllvGagglGcEllKnLvlaGvgsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnveaheesiteleeeivFfkkfdvVvlaldn 119
           akvl+vGagglGcEllK L+l+G++++ v+Dmd++ev+nlnrqFLfr edvgk+KAevaa+++ e+ + vn+++h ++i+++e e  F+++f++++l+ld+
   Q: 48   AKVLVVGAGGLGCELLKDLALSGFRNLDVIDMDRIEVTNLNRQFLFRLEDVGKPKAEVAAKRVMERISGVNIVPHFCRIEDKEIE--FYNDFSIIALGLDS 146
           79********************************************************************************888..************** PP
   S: 120  rearrkvnrlclna.............rvpliesgtlGllGqvrviikgltecyscsd..dppqktiPfctlketpnaaehtiewavlf 193
           +ear ++n++ ++               +p++++gt+G++G++rvi++g+t c +c+    ppq+++P+ctl+etp++a h+ie+a+l+
   Q: 147  IEARSYINTVACSFleydsddnpreetIKPMVDGGTEGFKGHARVIMPGITPCFECTIwlFPPQVKFPLCTLAETPRTAAHCIEYAHLI 235
           **************************************************************************************554 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MADTSAQIQQ QQPSRSRDLD KLLLRPGNLV GPRFEPGAEL RDDLQEFAKV LVVGAGGLGC 60
ELLKDLALSG FRNLDVIDMD RIEVTNLNRQ FLFRLEDVGK PKAEVAAKRV MERISGVNIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGATA CCTCAGCGCA AATTCAACAA CAACAACCAA GTCGATCAAG GGACCTCGAC 60
AAACTCCTTC TCCGACCCGG CAATCTTGTG GGTCCCAGGT TCGAACCTGG CGCAGAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014929--E2_binding
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR030468--Uba3
IPR033127--UBQ-activ_enz_E1_Cys_AS

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF08825--E2_bind
PF00899--ThiF

SMART

SM01181--E2_bind

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0005524--F:ATP binding
GO:0019781--F:NEDD8 activating enzyme activity
GO:0045116--P:protein neddylation

KEGG

mtr:MTR_4g131690

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001124	Aegilops tauschii	76.34	2.00e-166	577.00
IUUC-Aml-001578	Ailuropoda melanoleuca	48.88	4.00e-108	384.00
IUUC-Atr-002591	Amborella trichopoda	82.81	0.00e+00	703.00
IUUC-Apl-003671	Anas platyrhynchos	49.87	2.00e-109	388.00
IUUC-Aca-004749	Anolis carolinensis	49.88	1.00e-109	389.00
IUUC-Aly-005747	Arabidopsis lyrata	77.97	0.00e+00	701.00
IUUC-Ath-006623	Arabidopsis thaliana	76.92	0.00e+00	690.00
IUUC-Ago-007934	Ashbya gossypii	38.99	4.00e-59	220.00
IUUC-Acl-008047	Aspergillus clavatus	48.13	5.00e-110	390.00
IUUC-Afl-008615	Aspergillus flavus	43.33	6.00e-70	257.00
IUUC-Afu-008996	Aspergillus fumigatus	50.90	3.00e-101	361.00
IUUC-Ani-009281	Aspergillus nidulans	47.11	2.00e-73	268.00
IUUC-Ang-009539	Aspergillus niger	49.62	2.00e-99	355.00
IUUC-Aor-010151	Aspergillus oryzae	48.06	3.00e-95	341.00
IUUC-Ate-010502	Aspergillus terreus	50.63	6.00e-100	357.00
IUUC-Ame-011837	Astyanax mexicanus	48.13	3.00e-99	355.00
IUUC-Bgr-012068	Blumeria graminis	52.08	5.00e-98	350.00
IUUC-Bta-013003	Bos taurus	50.12	1.00e-109	389.00
IUUC-Bci-013983	Botrytis cinerea	49.26	4.00e-100	357.00
IUUC-Bdi-014429	Brachypodium distachyon	75.23	5.00e-180	623.00
IUUC-Bol-015813	Brassica oleracea	83.22	0.00e+00	692.00
IUUC-Bra-018023	Brassica rapa	82.65	0.00e+00	685.00
IUUC-Cel-018684	Caenorhabditis elegans	48.99	4.00e-104	370.00
IUUC-Cja-019200	Callithrix jacchus	49.63	6.00e-107	380.00
IUUC-Cfa-021038	Canis familiaris	49.75	2.00e-109	388.00
IUUC-Cre-022778	Chlamydomonas reinhardtii	59.71	4.00e-139	487.00
IUUC-Csa-024079	Chlorocebus sabaeus	49.38	2.00e-109	388.00
IUUC-Cho-025052	Choloepus hoffmanni	43.39	3.00e-89	321.00
IUUC-Cin-025113	Ciona intestinalis	49.00	3.00e-102	364.00
IUUC-Csv-026231	Ciona savignyi	48.50	1.00e-107	382.00
IUUC-Cgl-026535	Colletotrichum gloeosporioides	47.84	4.00e-96	344.00
IUUC-Cne-026850	Cryptococcus neoformans	48.41	1.00e-99	356.00
IUUC-Cme-027275	Cyanidioschyzon merolae	37.17	2.00e-72	265.00
IUUC-Dre-028751	Danio rerio	46.75	7.00e-99	353.00
IUUC-Dno-029571	Dasypus novemcinctus	50.00	2.00e-108	385.00
IUUC-Dor-030395	Dipodomys ordii	50.25	5.00e-110	390.00
IUUC-Dse-031329	Dothistroma septosporum	44.39	1.00e-88	319.00
IUUC-Dme-031776	Drosophila melanogaster	47.90	4.00e-100	357.00
IUUC-Ete-032894	Echinops telfairi	49.10	9.00e-39	154.00
IUUC-Eca-034389	Equus caballus	49.63	2.00e-109	388.00
IUUC-Eeu-035152	Erinaceus europaeus	45.53	3.00e-82	298.00
IUUC-Fca-036032	Felis catus	49.13	1.00e-109	389.00
IUUC-Fal-037506	Ficedula albicollis	49.63	2.00e-109	389.00
IUUC-Fox-037871	Fusarium oxysporum	50.58	3.00e-88	317.00
IUUC-Fso-038350	Fusarium solani	50.77	6.00e-99	353.00
IUUC-Gmo-039647	Gadus morhua	48.63	2.00e-99	355.00
IUUC-Ggr-039859	Gaeumannomyces graminis	48.87	3.00e-97	348.00
IUUC-Gga-040843	Gallus gallus	48.88	7.00e-104	370.00
IUUC-Gac-042601	Gasterosteus aculeatus	48.76	9.00e-100	356.00
IUUC-Gma-042744	Glycine max	95.10	0.00e+00	782.00
IUUC-Ggo-044788	Gorilla gorilla	49.50	3.00e-108	384.00
IUUC-Hsa-045849	Homo sapiens	49.63	1.00e-109	389.00
IUUC-Hvu-047819	Hordeum vulgare	79.89	1.00e-148	518.00
IUUC-Itr-047863	Ictidomys tridecemlineatus	48.99	5.00e-108	384.00
IUUC-Kpa-049393	Komagataella pastoris	49.06	5.00e-83	300.00
IUUC-Lch-049471	Latimeria chalumnae	47.63	2.00e-98	351.00
IUUC-Lpe-051297	Leersia perrieri	74.03	0.00e+00	647.00
IUUC-Loc-052910	Lepisosteus oculatus	48.63	3.00e-98	351.00
IUUC-Lma-053181	Leptosphaeria maculans	48.76	4.00e-98	350.00
IUUC-Laf-054314	Loxodonta africana	49.26	3.00e-107	381.00
IUUC-Mcc-054870	Macaca mulatta	49.63	2.00e-109	389.00
IUUC-Meu-056574	Macropus eugenii	38.99	1.00e-43	169.00
IUUC-Mor-056919	Magnaporthe oryzae	48.54	1.00e-99	355.00
IUUC-Mpo-057614	Magnaporthe poae	47.87	5.00e-91	327.00
IUUC-Mla-058949	Melampsora laricipopulina	45.34	6.00e-94	337.00
IUUC-Mga-059455	Meleagris gallopavo	49.63	1.00e-108	385.00
IUUC-Mvi-060270	Microbotryum violaceum	44.52	2.00e-98	352.00
IUUC-Mmr-061155	Microcebus murinus	49.87	2.00e-108	385.00
IUUC-Mdo-062037	Monodelphis domestica	50.00	2.00e-108	385.00
IUUC-Mmu-063670	Mus musculus	49.88	1.00e-109	389.00
IUUC-Mac-064711	Musa acuminata	76.74	3.00e-180	624.00
IUUC-Mpu-066734	Mustela putorius furo	49.63	2.00e-109	388.00
IUUC-Mlu-067068	Myotis lucifugus	50.00	8.00e-110	390.00
IUUC-Nfi-068349	Neosartorya fischeri	50.90	3.00e-101	361.00
IUUC-Ncr-068626	Neurospora crassa	48.48	3.00e-97	347.00
IUUC-Nle-069366	Nomascus leucogenys	51.69	5.00e-103	367.00
IUUC-Ont-072196	Oreochromis niloticus	48.25	2.00e-98	352.00
IUUC-Oan-073511	Ornithorhynchus anatinus	49.63	2.00e-108	385.00
IUUC-Ocu-073773	Oryctolagus cuniculus	49.63	1.00e-109	389.00
IUUC-Oba-075726	Oryza barthii	68.57	1.00e-170	592.00
IUUC-Obr-076286	Oryza brachyantha	74.94	0.00e+00	646.00
IUUC-Ogu-078473	Oryza glumaepatula	68.57	7.00e-171	592.00
IUUC-Oin-079393	Oryza indica	74.48	0.00e+00	646.00
IUUC-Olo-080446	Oryza longistaminata	71.69	2.00e-175	608.00
IUUC-Ome-081737	Oryza meridionalis	71.49	4.00e-174	603.00
IUUC-Oni-082853	Oryza nivara	68.57	1.00e-170	592.00
IUUC-Opu-083590	Oryza punctata	73.52	0.00e+00	640.00
IUUC-Oru-084184	Oryza rufipogon	68.57	1.00e-170	592.00
IUUC-Osa-085402	Oryza sativa	74.48	0.00e+00	646.00
IUUC-Ola-086615	Oryzias latipes	44.82	4.00e-93	334.00
IUUC-Olu-087738	Ostreococcus lucimarinus	58.88	4.00e-124	437.00
IUUC-Oga-088101	Otolemur garnettii	49.63	3.00e-109	387.00
IUUC-Oar-090293	Ovis aries	49.63	1.00e-107	383.00
IUUC-Ptr-090503	Pan troglodytes	49.63	1.00e-109	389.00
IUUC-Pan-092477	Papio anubis	48.25	1.00e-104	372.00
IUUC-Psi-093442	Pelodiscus sinensis	49.88	8.00e-111	393.00
IUUC-Pma-094247	Petromyzon marinus	49.63	5.00e-99	353.00
IUUC-Pno-094780	Phaeosphaeria nodorum	48.76	9.00e-99	353.00
IUUC-Ppa-095961	Physcomitrella patens	64.19	6.00e-172	596.00
IUUC-Pfo-096846	Poecilia formosa	48.88	3.00e-102	364.00
IUUC-Pab-098060	Pongo abelii	49.38	7.00e-101	360.00
IUUC-Pop-099914	Populus trichocarpa	85.31	0.00e+00	722.00
IUUC-Pca-100500	Procavia capensis	45.14	3.00e-73	268.00
IUUC-Ppe-102008	Prunus persica	85.48	0.00e+00	711.00
IUUC-Pva-103095	Pteropus vampyrus	56.63	7.00e-59	220.00
IUUC-Pgr-103666	Puccinia graminis	45.35	2.00e-100	358.00
IUUC-Ptt-103901	Puccinia triticina	47.83	2.00e-100	358.00
IUUC-Pte-104198	Pyrenophora teres	48.02	2.00e-97	348.00
IUUC-Pyt-104792	Pyrenophora triticirepentis	46.78	5.00e-94	337.00
IUUC-Rno-105446	Rattus norvegicus	50.12	6.00e-110	390.00
IUUC-Sce-106355	Saccharomyces cerevisiae	38.94	1.00e-58	218.00
IUUC-Sha-106664	Sarcophilus harrisii	49.25	1.00e-106	379.00
IUUC-Sja-107982	Schizosaccharomyces japonicus	41.94	6.00e-88	317.00
IUUC-Spo-108345	Schizosaccharomyces pombe	40.73	7.00e-90	323.00
IUUC-Ssl-108540	Sclerotinia sclerotiorum	47.10	4.00e-87	314.00
IUUC-Smo-109133	Selaginella moellendorffii	60.67	2.00e-164	570.00
IUUC-Sit-109724	Setaria italica	74.10	1.00e-179	622.00
IUUC-Sly-110916	Solanum lycopersicum	83.45	0.00e+00	724.00
IUUC-Stu-112236	Solanum tuberosum	83.22	0.00e+00	724.00
IUUC-Sar-113044	Sorex araneus	51.22	1.00e-104	372.00
IUUC-Sbi-114276	Sorghum bicolor	73.99	4.00e-180	623.00
IUUC-Sre-114963	Sporisorium reilianum	48.34	1.00e-98	352.00
IUUC-Ssc-116301	Sus scrofa	49.26	1.00e-107	382.00
IUUC-Tgu-117265	Taeniopygia guttata	49.63	5.00e-110	390.00
IUUC-Tru-117526	Takifugu rubripes	49.13	2.00e-98	352.00
IUUC-Tsy-119483	Tarsius syrichta	50.26	2.00e-107	382.00
IUUC-Tni-120363	Tetraodon nigroviridis	49.50	3.00e-101	361.00
IUUC-Tca-121731	Theobroma cacao	86.88	0.00e+00	748.00
IUUC-Tre-122221	Trichoderma reesei	50.29	1.00e-88	319.00
IUUC-Tvi-122352	Trichoderma virens	48.24	2.00e-98	352.00
IUUC-Tae-123864	Triticum aestivum	75.29	0.00e+00	627.00
IUUC-Tur-126070	Triticum urartu	75.63	1.00e-157	548.00
IUUC-Tme-127199	Tuber melanosporum	51.12	3.00e-98	351.00
IUUC-Tbe-128076	Tupaia belangeri	49.88	1.00e-109	389.00
IUUC-Ttr-128695	Tursiops truncatus	57.14	1.00e-40	160.00
IUUC-Uma-129638	Ustilago maydis	46.98	2.00e-98	352.00
IUUC-Vda-129963	Verticillium dahliae	49.61	9.00e-91	326.00
IUUC-Vpa-130637	Vicugna pacos	43.72	2.00e-87	315.00
IUUC-Vvi-131613	Vitis vinifera	83.92	0.00e+00	720.00
IUUC-Xtr-132924	Xenopus tropicalis	48.14	3.00e-98	351.00
IUUC-Xma-134209	Xiphophorus maculatus	49.13	3.00e-102	364.00
IUUC-Yli-134365	Yarrowia lipolytica	47.26	6.00e-95	340.00
IUUC-Zma-135941	Zea mays	67.21	1.00e-172	598.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence