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Basic Information Integrated Annotations

Tag Content
UUCD2 ID IUUC-Rno-105558
UUCD1 version UUC-RaN-00904
Ensembl Protein ID ENSRNOP00000027006.6
UniProt Accession Q6AY27; FBX17_RAT
Genbank Protein ID AAH79218.1
Protein Name F-box only protein 17
Genbank Nucleotide ID BC079218
Gene Name Fbxo17
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000019942.7 ENSRNOT00000027006.7 ENSRNOP00000027006.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/SCF/F-box 81.55 2.00e-104 375.00 IUUC-Hsa-045768
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Rattus norvegicus
Functional Description
(View)

Functional Description



     Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity).
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. Also recognizes sulfated glycans. Does not bind high-mannose glycoproteins (By similarity).
Protein Sequence
(Fasta)
MGAQPSRRRM TEAQHMALAE LPPELLLQVL SHVPPRALVT RCRPVCRAWR DLVDGPSVWL 60
LQLARDRSAE GRALYALAQS CPADRNGHDD FPLCALARFC LLAPLGRNLI YNSCGEQGFR 120
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Protein Fasta Sequence



>IUUC-Rno-105558|E3,F-box|Rattus norvegicus
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Nucleotide Sequence
(Fasta)
CCAGGCATCC TGACTAGGTC TGTGACCTTG GGAGGCTGAC GCACCGACTC CACTTCACCC 60
AGAGGACACC GGCGTCAGGA CATGGGAGCC CAGCCCTCGC GACGGCGGAT GACCGAAGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Rno-105558|E3,F-box|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR007397--F-box-assoc_dom
IPR001810--F-box_dom
IPR008979--Galactose-bd-like

PROSITE

PS51114--FBA
PS50181--FBOX

Pfam

PF12937--F-box-like
PF04300--FBA

SMART

SM01198--FBA
SM00256--FBOX

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0001948--F:glycoprotein binding

KEGG rno:292757
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000348 Aegilops tauschii 52.78 2.00e-03 37.00
IUUC-Aml-002175 Ailuropoda melanoleuca 88.35 4.00e-106 377.00
IUUC-Aly-006011 Arabidopsis lyrata 36.36 5.00e-04 38.10
IUUC-Bta-012403 Bos taurus 84.19 1.00e-108 385.00
IUUC-Bdi-014875 Brachypodium distachyon 32.50 1.70e-01 30.00
IUUC-Bra-016666 Brassica rapa 44.44 4.30e-02 32.00
IUUC-Cja-019664 Callithrix jacchus 78.72 6.00e-106 376.00
IUUC-Cfa-020507 Canis familiaris 82.48 3.00e-102 364.00
IUUC-Cpo-021692 Cavia porcellus 83.26 2.00e-104 371.00
IUUC-Csa-023237 Chlorocebus sabaeus 81.97 3.00e-105 374.00
IUUC-Dno-030010 Dasypus novemcinctus 83.50 2.00e-98 352.00
IUUC-Dor-030171 Dipodomys ordii 85.84 9.00e-110 389.00
IUUC-Eca-034121 Equus caballus 91.40 7.00e-47 179.00
IUUC-Eeu-034490 Erinaceus europaeus 75.54 6.00e-95 340.00
IUUC-Fca-036454 Felis catus 64.75 7.00e-71 260.00
IUUC-Hsa-045768 Homo sapiens 81.55 2.00e-105 374.00
IUUC-Lpe-051277 Leersia perrieri 62.50 8.00e-03 31.20
IUUC-Laf-054235 Loxodonta africana 93.18 7.00e-45 172.00
IUUC-Mcc-054716 Macaca mulatta 69.96 6.00e-82 296.00
IUUC-Mpo-057547 Magnaporthe poae 31.03 5.90e-02 29.30
IUUC-Mtr-057739 Medicago truncatula 32.39 1.20e-02 34.30
IUUC-Mmr-061741 Microcebus murinus 85.44 8.00e-104 369.00
IUUC-Mdo-062210 Monodelphis domestica 51.26 1.00e-56 213.00
IUUC-Mmu-063186 Mus musculus 87.55 9.00e-115 406.00
IUUC-Mpu-066676 Mustela putorius furo 85.90 2.00e-109 388.00
IUUC-Mlu-067553 Myotis lucifugus 92.31 2.00e-61 228.00
IUUC-Nle-069434 Nomascus leucogenys 81.97 3.00e-105 374.00
IUUC-Opr-070811 Ochotona princeps 83.33 2.00e-59 222.00
IUUC-Ocu-074614 Oryctolagus cuniculus 86.56 2.00e-95 342.00
IUUC-Olo-080883 Oryza longistaminata 45.65 3.00e-03 34.30
IUUC-Ome-081576 Oryza meridionalis 40.00 6.00e-04 38.90
IUUC-Oni-082669 Oryza nivara 31.58 5.00e-05 42.40
IUUC-Opu-083853 Oryza punctata 41.67 2.10e-02 33.50
IUUC-Oru-084840 Oryza rufipogon 31.58 6.00e-05 42.40
IUUC-Osa-085304 Oryza sativa 34.15 1.80e-01 30.40
IUUC-Oga-088143 Otolemur garnettii 81.55 1.00e-104 372.00
IUUC-Oar-089201 Ovis aries 92.31 6.00e-62 229.00
IUUC-Pan-092112 Papio anubis 81.55 8.00e-105 372.00
IUUC-Pab-098059 Pongo abelii 81.12 6.00e-106 376.00
IUUC-Pca-100353 Procavia capensis 68.80 3.00e-84 304.00
IUUC-Pva-102310 Pteropus vampyrus 83.69 6.00e-108 383.00
IUUC-Sha-106875 Sarcophilus harrisii 52.94 9.00e-49 186.00
IUUC-Sar-113465 Sorex araneus 73.53 3.00e-83 300.00
IUUC-Sbi-114168 Sorghum bicolor 48.28 1.80e-01 30.80
IUUC-Ssc-115935 Sus scrofa 70.39 5.00e-66 243.00
IUUC-Tae-122782 Triticum aestivum 62.96 4.00e-03 36.20
IUUC-Tur-126828 Triticum urartu 62.96 3.00e-03 36.60
IUUC-Tbe-128039 Tupaia belangeri 86.17 3.00e-44 170.00
IUUC-Ttr-129139 Tursiops truncatus 81.62 1.00e-81 295.00
Created Date 25-Jun-2017

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