iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ppa-095227

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Predicted protein

Genbank Nucleotide ID

DS544963

Gene Name

PHYPADRAFT_129081

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PP1S74_65V6	PP1S74_65V6.1	PP1S74_65V6.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.80e-171	570.6	454	940

Active Site

Position(s)	Description	Evidence
595	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvnve 91
           YD Qi+++G++ q+kl+++k +lvGag+lGcE+lKnL+l+Gv     g++tv+D+d +e+snl+rqFLfr++++g+ K+ va  a+  +np+ n++
   Q: 454  YDAQIAVFGSKVQQKLEQSKLFLVGAGALGCEFLKNLALMGVscgpkGNLTVTDDDVIEKSNLSRQFLFRDWNIGQAKSTVASSAAIAINPSFNAV 549
           ************************************************************************************************ PP
   S: 92   aheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaae 184
           a ++++++ +e+++   F + +d+Vv+aldn+ ar++++++c++ ++pl+esgtlG++ +++v+i+ lte y +s+dpp+k++P+ct+ ++p +++
   Q: 550  ALQNRVSPNTENVFddtFWEGLDLVVNALDNVNARLYIDSRCVYFQKPLLESGTLGTKCNTQVVIPNLTENYGASRDPPEKQAPMCTVHSFPHNID 645
           ************99999******************************************************************************* PP
   S: 185  htiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtks 268
           h+++wa            + +n +l++ ++ ++ +++   ++ +e +++v + l++e+  +fee+i++a+  f+ +++n +kql+  f+ d  t++
   Q: 646  HCLTWArsefegllektpAEANAFLSKPEEYKTAAKNAGDAQARELLERVVECLVTERCASFEECITWARLRFEDYFSNRVKQLTFTFPEDATTSN 741
           *****************99999************************************************************************** PP
   S: 269  kspfwv..........................................................sfcsnaealqvpekvekdeevvkasap.lyll 305
           + pfw+                                                            +++  ++ ++ek+++    + ++++ +++l
   Q: 742  GLPFWSapkrfpkplqffssdpsclsfvaaaailrattfgisvpawaldarklaeavdkvkvpdFAPKQGVKIVTDEKATSINSSSMDDDYqIEML 837
           ************************************************999555555555444333333333344466666655555555599999 PP
   S: 306  lralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg.kfeplk 396
           +++l++  kk  +g k++ ++fekddd   ++dl++ +an+ra ++++++ +d+ + k iag+iipaiatt+a+  Gl+++E++Kv+ g   e ++
   Q: 838  IKILDEGVKKlpPGFKMNPVTFEKDDDTnfHMDLIAGLANMRARNYSVPE-VDRLKAKFIAGRIIPAIATTTAMATGLVCLELYKVILGhNVERYR 932
           99999877765589************************************.************************************9978889** PP
   S: 397  nfflfdae 404
           n+f ++a+
   Q: 933  NTFANLAL 940
           ***99875 PP

Organism

Physcomitrella patens

Protein Sequence
(Fasta)

MLPKKRESGE EAEFGKNSLK RKRVEPSSGS VVLGKNRELV MAPDSNMEVE IDEDLHSRQL 60
AVYGRETMRR LFGAQVLISG LQGLGVEIAK NVILAGVKSV TLHDAGNVEL WDLSAQFYFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCCTGCCGA GCGACGCTTC GTAGCGGAGG AAGCTGTGAC GTTGCTTCGC CCTCCGATCT 60
TCGTCTCCCC GTCGCCAGGT CCGTTTCTTC TTCGTCTTCT TCCTCTTCTT CTGCATGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

ppp:PHYPADRAFT_129081

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000456	Aegilops tauschii	74.09	0.00e+00	1542.00
IUUC-Apl-004158	Anas platyrhynchos	39.40	0.00e+00	671.00
IUUC-Aly-005515	Arabidopsis lyrata	71.72	0.00e+00	1513.00
IUUC-Ath-006891	Arabidopsis thaliana	71.53	0.00e+00	1508.00
IUUC-Ago-007873	Ashbya gossypii	45.48	0.00e+00	831.00
IUUC-Acl-008181	Aspergillus clavatus	46.05	0.00e+00	841.00
IUUC-Afl-008455	Aspergillus flavus	47.04	0.00e+00	835.00
IUUC-Afu-009065	Aspergillus fumigatus	46.89	0.00e+00	877.00
IUUC-Ani-009371	Aspergillus nidulans	47.66	0.00e+00	854.00
IUUC-Aor-010007	Aspergillus oryzae	47.04	0.00e+00	835.00
IUUC-Ate-010466	Aspergillus terreus	47.09	0.00e+00	879.00
IUUC-Ame-010933	Astyanax mexicanus	45.81	0.00e+00	865.00
IUUC-Bgr-012281	Blumeria graminis	46.00	0.00e+00	836.00
IUUC-Bci-013721	Botrytis cinerea	47.21	0.00e+00	819.00
IUUC-Bdi-014843	Brachypodium distachyon	71.23	0.00e+00	1487.00
IUUC-Bol-015880	Brassica oleracea	71.84	0.00e+00	1532.00
IUUC-Bra-017252	Brassica rapa	71.93	0.00e+00	1532.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	62.60	0.00e+00	1224.00
IUUC-Cho-024682	Choloepus hoffmanni	35.63	4.00e-97	348.00
IUUC-Cin-025790	Ciona intestinalis	44.36	0.00e+00	853.00
IUUC-Csv-026084	Ciona savignyi	43.95	0.00e+00	849.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	47.81	0.00e+00	890.00
IUUC-Cne-026960	Cryptococcus neoformans	47.25	0.00e+00	885.00
IUUC-Dme-032045	Drosophila melanogaster	46.34	0.00e+00	869.00
IUUC-Fal-036848	Ficedula albicollis	40.13	0.00e+00	682.00
IUUC-Fso-038339	Fusarium solani	47.41	0.00e+00	843.00
IUUC-Gmo-039338	Gadus morhua	44.68	0.00e+00	832.00
IUUC-Gga-040747	Gallus gallus	40.06	0.00e+00	672.00
IUUC-Gac-041773	Gasterosteus aculeatus	44.13	0.00e+00	838.00
IUUC-Gma-043165	Glycine max	72.62	0.00e+00	1542.00
IUUC-Hvu-047418	Hordeum vulgare	73.52	0.00e+00	1499.00
IUUC-Kpa-049112	Komagataella pastoris	46.26	0.00e+00	856.00
IUUC-Lpe-051299	Leersia perrieri	72.08	0.00e+00	1515.00
IUUC-Lma-053315	Leptosphaeria maculans	46.65	0.00e+00	886.00
IUUC-Mtr-058572	Medicago truncatula	72.62	0.00e+00	1489.00
IUUC-Mla-059176	Melampsora laricipopulina	47.62	0.00e+00	873.00
IUUC-Mga-059721	Meleagris gallopavo	40.63	0.00e+00	651.00
IUUC-Mvi-060437	Microbotryum violaceum	44.87	0.00e+00	811.00
IUUC-Mac-065505	Musa acuminata	72.36	0.00e+00	1508.00
IUUC-Nfi-068407	Neosartorya fischeri	47.22	0.00e+00	862.00
IUUC-Ncr-068698	Neurospora crassa	47.76	0.00e+00	885.00
IUUC-Opr-070715	Ochotona princeps	36.45	2.00e-151	529.00
IUUC-Ont-071671	Oreochromis niloticus	45.99	0.00e+00	881.00
IUUC-Ocu-074544	Oryctolagus cuniculus	46.04	0.00e+00	911.00
IUUC-Oba-075120	Oryza barthii	71.44	0.00e+00	1498.00
IUUC-Obr-076557	Oryza brachyantha	73.76	0.00e+00	1503.00
IUUC-Ogl-077887	Oryza glaberrima	71.35	0.00e+00	1499.00
IUUC-Ome-081942	Oryza meridionalis	71.42	0.00e+00	1502.00
IUUC-Oni-082365	Oryza nivara	71.51	0.00e+00	1502.00
IUUC-Opu-083301	Oryza punctata	73.66	0.00e+00	1498.00
IUUC-Osa-085949	Oryza sativa	71.35	0.00e+00	1526.00
IUUC-Ola-087002	Oryzias latipes	46.62	0.00e+00	881.00
IUUC-Ptr-090609	Pan troglodytes	39.28	0.00e+00	664.00
IUUC-Pno-095154	Phaeosphaeria nodorum	45.23	0.00e+00	846.00
IUUC-Pfo-097184	Poecilia formosa	45.02	0.00e+00	863.00
IUUC-Pop-099577	Populus trichocarpa	68.91	0.00e+00	1518.00
IUUC-Pca-100347	Procavia capensis	44.25	0.00e+00	720.00
IUUC-Ppe-102012	Prunus persica	70.98	0.00e+00	1523.00
IUUC-Pva-102584	Pteropus vampyrus	45.75	0.00e+00	919.00
IUUC-Ptt-103939	Puccinia triticina	46.07	0.00e+00	815.00
IUUC-Pte-104200	Pyrenophora teres	46.30	0.00e+00	872.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	45.68	0.00e+00	867.00
IUUC-Sce-106245	Saccharomyces cerevisiae	46.49	0.00e+00	859.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	46.40	0.00e+00	858.00
IUUC-Spo-108034	Schizosaccharomyces pombe	45.73	0.00e+00	839.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	45.57	0.00e+00	826.00
IUUC-Sit-110281	Setaria italica	72.20	0.00e+00	1533.00
IUUC-Sly-110914	Solanum lycopersicum	72.57	0.00e+00	1529.00
IUUC-Stu-112109	Solanum tuberosum	72.48	0.00e+00	1537.00
IUUC-Sbi-114089	Sorghum bicolor	72.20	0.00e+00	1535.00
IUUC-Sre-115148	Sporisorium reilianum	44.56	0.00e+00	808.00
IUUC-Tgu-116565	Taeniopygia guttata	39.81	0.00e+00	675.00
IUUC-Tru-118742	Takifugu rubripes	45.70	0.00e+00	838.00
IUUC-Tni-120401	Tetraodon nigroviridis	45.72	0.00e+00	838.00
IUUC-Tca-121436	Theobroma cacao	71.74	0.00e+00	1522.00
IUUC-Tre-122009	Trichoderma reesei	47.70	0.00e+00	844.00
IUUC-Tvi-122259	Trichoderma virens	47.80	0.00e+00	841.00
IUUC-Tae-125113	Triticum aestivum	73.79	0.00e+00	1485.00
IUUC-Tur-126330	Triticum urartu	73.99	0.00e+00	1543.00
IUUC-Tbe-127587	Tupaia belangeri	41.79	1.00e-139	490.00
IUUC-Uma-129387	Ustilago maydis	44.84	0.00e+00	818.00
IUUC-Vda-129977	Verticillium dahliae	48.51	0.00e+00	829.00
IUUC-Vvi-130857	Vitis vinifera	72.72	0.00e+00	1522.00
IUUC-Xma-133805	Xiphophorus maculatus	44.73	0.00e+00	845.00
IUUC-Yli-134547	Yarrowia lipolytica	47.01	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence