iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tre-122009

Ensembl Protein ID

EGR51103

UniProt Accession

G0RBR9; G0RBR9_HYPJQ

Genbank Protein ID

EGR51103.1

Protein Name

Ubiquitin-activating enzyme

Genbank Nucleotide ID

GL985058

Gene Name

TRIREDRAFT_72606

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIREDRAFT_72606	EGR51103	EGR51103

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	3.50e-197	654.5	425	909

Active Site

Position(s)	Description	Evidence
608	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkelnpdvn..veahe 94
           YD+Qi+++G e q+k+ + k +lvGag++GcE+lKn +++G+     g+i+v+Dmd +e+snlnrqFLfra dvg  K+++aa+a++++np  +  +e   
   Q: 425  YDGQIAVFGTEFQKKIANMKQFLVGAGAIGCEMLKNWAMIGLgtgpnGKIYVTDMDSIEKSNLNRQFLFRAADVGSMKSDCAAKAVQRMNPELEghIETLR 525
           ********************************************************************************************972256677 PP
   S: 95   esiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiPfctlketpnaaehtiewa.. 190
           e++++++e+++   F k +d+V +aldn+ear++v+r c+ +++pl+esgtlG++G+++v+++ lte+ys+s dpp+k++P+ct++++pn++ehti wa  
   Q: 526  ERVSPETEHVFddaFWKSLDGVTNALDNVEARTYVDRKCVFYHKPLLESGTLGTKGNTQVVLPRLTESYSSSHDPPEKEFPMCTIRSFPNKIEHTIAWAke 626
           99*******99****************************************************************************************** PP
   S: 191  ...........vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafakttinsikqllksfecdivtkskspfwv...... 274
                        +n +l + ++ e +l+  +  +++e+++ +++ l++e++++fe++i++a++ f++ ++n+++qll +f++d vt+ ++pfw+      
   Q: 627  ymfekcfvkapQTVNLYLTQPNFIEATLK--QGGNQKETLETIRNYLTTERPRTFEDCIAWARQLFETEFSNKVQQLLYNFPKDSVTSGGTPFWSgpkrap 725
           77777777777667777766666666666..578889999999999999**************************************************** PP
   S: 275  ..................................................sfcsnaealqvpekvekdeevvkasap..........lylllralerfekk 315
                                                                       +p++++k ++ +k+++p          l  l ++l + ++ 
   Q: 726  dalkfdpnnethlgfiiaaanlhaynfnikspgndksiylkelenvivpdF---------TPDSNVKIQADDKEPDPnassfddtneLTELSASLPSPSSL 817
           ***888888888888888888888888888777777777765555555541.........33444444444444444444455555699************ PP
   S: 316  kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniipaiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
            g + + ++fekddd   ++d++ta++nlrae+++iep +d++++k iag+iipaiatt+a v Gl+++E++K+++g  + e++kn f+++a+
   Q: 818  AGFQLQPVEFEKDDDTnyHIDFITACSNLRAENYKIEP-ADRHKTKFIAGKIIPAIATTTALVTGLVVLELYKIIDGkdDIEQYKNGFINLAL 909
           **************************************.**************************************777889******9875 PP

Organism

Trichoderma reesei

Protein Sequence
(Fasta)

MAAAKLPEVD LATRMQVDDS VVGTTEIDES LYSRQLYVLG HEAMRRMGAS NILVVGLKGL 60
GVEIAKNIAL AGVKSLTLYD PAPVQIADLS AQFFLTPEDV GKPRDEVTAP RVAELNAYTP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTCCAATT CTCTCTTCCA CCAGCCTGTT CTTGTCGTTT CCCGGCGAGA ATTCTGTGTG 60
CAGACGACGA TTTCTGGCAC AGCCAAACGC AAGGAAACGC TCACACCCTA CCTACCTAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004839--F:ubiquitin activating enzyme activity

KEGG

tre:TRIREDRAFT_72606

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000367	Aegilops tauschii	46.73	0.00e+00	828.00
IUUC-Aml-001311	Ailuropoda melanoleuca	54.02	0.00e+00	1085.00
IUUC-Atr-002684	Amborella trichopoda	46.91	0.00e+00	878.00
IUUC-Apl-004158	Anas platyrhynchos	42.37	0.00e+00	688.00
IUUC-Aca-004620	Anolis carolinensis	54.80	0.00e+00	1078.00
IUUC-Aly-005418	Arabidopsis lyrata	47.61	0.00e+00	893.00
IUUC-Ath-006891	Arabidopsis thaliana	46.91	0.00e+00	895.00
IUUC-Ago-007873	Ashbya gossypii	60.10	0.00e+00	1162.00
IUUC-Acl-008181	Aspergillus clavatus	69.03	0.00e+00	1450.00
IUUC-Afl-008455	Aspergillus flavus	70.16	0.00e+00	1401.00
IUUC-Afu-009065	Aspergillus fumigatus	69.86	0.00e+00	1475.00
IUUC-Ani-009371	Aspergillus nidulans	70.07	0.00e+00	1438.00
IUUC-Ang-009737	Aspergillus niger	69.97	0.00e+00	1454.00
IUUC-Aor-010007	Aspergillus oryzae	70.16	0.00e+00	1401.00
IUUC-Ate-010466	Aspergillus terreus	68.93	0.00e+00	1479.00
IUUC-Ame-010933	Astyanax mexicanus	53.33	0.00e+00	1016.00
IUUC-Bgr-012281	Blumeria graminis	70.35	0.00e+00	1492.00
IUUC-Bta-012767	Bos taurus	54.06	0.00e+00	1087.00
IUUC-Bci-013721	Botrytis cinerea	73.55	0.00e+00	1510.00
IUUC-Bdi-014009	Brachypodium distachyon	46.82	0.00e+00	869.00
IUUC-Bol-015665	Brassica oleracea	46.88	0.00e+00	878.00
IUUC-Bra-017252	Brassica rapa	47.06	0.00e+00	887.00
IUUC-Cel-018260	Caenorhabditis elegans	45.52	0.00e+00	807.00
IUUC-Cja-019152	Callithrix jacchus	54.11	0.00e+00	1084.00
IUUC-Cfa-020622	Canis familiaris	52.65	0.00e+00	1047.00
IUUC-Cpo-022526	Cavia porcellus	54.56	0.00e+00	1063.00
IUUC-Cre-022702	Chlamydomonas reinhardtii	44.12	0.00e+00	786.00
IUUC-Csa-023780	Chlorocebus sabaeus	54.31	0.00e+00	1082.00
IUUC-Cho-024682	Choloepus hoffmanni	42.41	4.00e-100	357.00
IUUC-Cin-025790	Ciona intestinalis	52.18	0.00e+00	1061.00
IUUC-Csv-026084	Ciona savignyi	52.03	0.00e+00	1052.00
IUUC-Cgl-026512	Colletotrichum gloeosporioides	79.57	0.00e+00	1727.00
IUUC-Cne-026960	Cryptococcus neoformans	59.55	0.00e+00	1177.00
IUUC-Cme-027290	Cyanidioschyzon merolae	43.88	0.00e+00	784.00
IUUC-Dre-028149	Danio rerio	53.91	0.00e+00	1056.00
IUUC-Dno-028884	Dasypus novemcinctus	54.12	0.00e+00	1084.00
IUUC-Dor-030229	Dipodomys ordii	50.98	0.00e+00	1014.00
IUUC-Dse-031524	Dothistroma septosporum	68.84	0.00e+00	1421.00
IUUC-Dme-032045	Drosophila melanogaster	52.17	0.00e+00	1031.00
IUUC-Ete-033124	Echinops telfairi	43.66	1.00e-152	532.00
IUUC-Eca-033330	Equus caballus	54.12	0.00e+00	1083.00
IUUC-Eeu-035323	Erinaceus europaeus	42.57	6.00e-152	530.00
IUUC-Fca-036255	Felis catus	54.02	0.00e+00	1080.00
IUUC-Fal-036848	Ficedula albicollis	42.70	0.00e+00	697.00
IUUC-Fox-038007	Fusarium oxysporum	85.15	0.00e+00	954.00
IUUC-Fso-038339	Fusarium solani	85.69	0.00e+00	1759.00
IUUC-Gmo-039338	Gadus morhua	52.30	0.00e+00	1011.00
IUUC-Ggr-039823	Gaeumannomyces graminis	73.87	0.00e+00	1646.00
IUUC-Gga-040747	Gallus gallus	43.00	0.00e+00	685.00
IUUC-Gac-041773	Gasterosteus aculeatus	51.86	0.00e+00	1023.00
IUUC-Gma-043198	Glycine max	47.41	0.00e+00	876.00
IUUC-Ggo-045336	Gorilla gorilla	54.12	0.00e+00	1065.00
IUUC-Hsa-045982	Homo sapiens	54.02	0.00e+00	1063.00
IUUC-Hvu-047418	Hordeum vulgare	46.93	0.00e+00	855.00
IUUC-Itr-048460	Ictidomys tridecemlineatus	54.31	0.00e+00	1081.00
IUUC-Kpa-049112	Komagataella pastoris	59.65	0.00e+00	1159.00
IUUC-Lch-050371	Latimeria chalumnae	54.80	0.00e+00	1070.00
IUUC-Lpe-051299	Leersia perrieri	46.13	0.00e+00	870.00
IUUC-Loc-052936	Lepisosteus oculatus	54.55	0.00e+00	1069.00
IUUC-Lma-053315	Leptosphaeria maculans	69.83	0.00e+00	1483.00
IUUC-Laf-053948	Loxodonta africana	53.43	0.00e+00	1050.00
IUUC-Mcc-055843	Macaca mulatta	54.12	0.00e+00	1082.00
IUUC-Meu-056258	Macropus eugenii	54.50	0.00e+00	1075.00
IUUC-Mor-057269	Magnaporthe oryzae	75.34	0.00e+00	1616.00
IUUC-Mpo-057435	Magnaporthe poae	74.64	0.00e+00	1612.00
IUUC-Mtr-058572	Medicago truncatula	47.25	0.00e+00	862.00
IUUC-Mla-059176	Melampsora laricipopulina	59.09	0.00e+00	1140.00
IUUC-Mga-059721	Meleagris gallopavo	42.65	0.00e+00	665.00
IUUC-Mvi-060437	Microbotryum violaceum	56.74	0.00e+00	1142.00
IUUC-Mmr-061405	Microcebus murinus	52.94	0.00e+00	1040.00
IUUC-Mdo-062032	Monodelphis domestica	52.18	0.00e+00	1026.00
IUUC-Mmu-063280	Mus musculus	53.78	0.00e+00	1075.00
IUUC-Mac-065505	Musa acuminata	46.80	0.00e+00	884.00
IUUC-Mpu-066409	Mustela putorius furo	54.22	0.00e+00	1088.00
IUUC-Mlu-067217	Myotis lucifugus	53.73	0.00e+00	1060.00
IUUC-Nfi-068407	Neosartorya fischeri	69.46	0.00e+00	1460.00
IUUC-Ncr-068698	Neurospora crassa	77.39	0.00e+00	1648.00
IUUC-Nle-070072	Nomascus leucogenys	51.47	0.00e+00	983.00
IUUC-Opr-070715	Ochotona princeps	39.73	2.00e-180	624.00
IUUC-Ont-071671	Oreochromis niloticus	54.35	0.00e+00	1060.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.36	0.00e+00	644.00
IUUC-Ocu-074544	Oryctolagus cuniculus	54.41	0.00e+00	1092.00
IUUC-Oba-075120	Oryza barthii	47.58	0.00e+00	859.00
IUUC-Obr-076557	Oryza brachyantha	47.26	0.00e+00	842.00
IUUC-Ogl-077887	Oryza glaberrima	47.58	0.00e+00	861.00
IUUC-Ogu-078793	Oryza glumaepatula	46.18	0.00e+00	862.00
IUUC-Oin-079710	Oryza indica	45.88	0.00e+00	860.00
IUUC-Olo-081089	Oryza longistaminata	46.13	0.00e+00	862.00
IUUC-Ome-081942	Oryza meridionalis	47.38	0.00e+00	859.00
IUUC-Oni-082365	Oryza nivara	47.58	0.00e+00	862.00
IUUC-Opu-083977	Oryza punctata	47.35	0.00e+00	860.00
IUUC-Oru-085015	Oryza rufipogon	46.18	0.00e+00	862.00
IUUC-Osa-085949	Oryza sativa	47.48	0.00e+00	866.00
IUUC-Ola-087002	Oryzias latipes	54.00	0.00e+00	1063.00
IUUC-Olu-087687	Ostreococcus lucimarinus	44.11	0.00e+00	766.00
IUUC-Oga-088594	Otolemur garnettii	53.97	0.00e+00	1056.00
IUUC-Oar-090068	Ovis aries	53.88	0.00e+00	1085.00
IUUC-Ptr-090609	Pan troglodytes	42.64	0.00e+00	691.00
IUUC-Pan-092114	Papio anubis	54.22	0.00e+00	1083.00
IUUC-Psi-093489	Pelodiscus sinensis	41.99	0.00e+00	694.00
IUUC-Pma-094214	Petromyzon marinus	44.13	6.00e-39	151.00
IUUC-Pno-095154	Phaeosphaeria nodorum	68.52	0.00e+00	1465.00
IUUC-Ppa-095227	Physcomitrella patens	47.70	0.00e+00	881.00
IUUC-Pfo-097184	Poecilia formosa	53.82	0.00e+00	1060.00
IUUC-Pab-097861	Pongo abelii	54.22	0.00e+00	1055.00
IUUC-Pop-098934	Populus trichocarpa	47.31	0.00e+00	890.00
IUUC-Pca-100347	Procavia capensis	52.06	0.00e+00	892.00
IUUC-Ppe-102012	Prunus persica	47.17	0.00e+00	896.00
IUUC-Pva-102584	Pteropus vampyrus	54.22	0.00e+00	1111.00
IUUC-Pgr-103336	Puccinia graminis	57.39	0.00e+00	1108.00
IUUC-Ptt-103939	Puccinia triticina	57.71	0.00e+00	1087.00
IUUC-Pte-104200	Pyrenophora teres	70.42	0.00e+00	1493.00
IUUC-Pyt-104441	Pyrenophora triticirepentis	68.85	0.00e+00	1479.00
IUUC-Rno-105462	Rattus norvegicus	54.07	0.00e+00	1074.00
IUUC-Sce-106245	Saccharomyces cerevisiae	59.16	0.00e+00	1189.00
IUUC-Sha-107142	Sarcophilus harrisii	53.33	0.00e+00	1068.00
IUUC-Sja-107841	Schizosaccharomyces japonicus	58.19	0.00e+00	1198.00
IUUC-Spo-108034	Schizosaccharomyces pombe	57.91	0.00e+00	1171.00
IUUC-Ssl-108497	Sclerotinia sclerotiorum	73.81	0.00e+00	1523.00
IUUC-Smo-108912	Selaginella moellendorffii	47.08	0.00e+00	858.00
IUUC-Sit-110281	Setaria italica	47.50	0.00e+00	874.00
IUUC-Sly-110914	Solanum lycopersicum	46.91	0.00e+00	906.00
IUUC-Stu-112109	Solanum tuberosum	46.42	0.00e+00	907.00
IUUC-Sar-113737	Sorex araneus	54.02	0.00e+00	1081.00
IUUC-Sbi-114520	Sorghum bicolor	47.80	0.00e+00	884.00
IUUC-Sre-115148	Sporisorium reilianum	57.86	0.00e+00	1125.00
IUUC-Ssc-115777	Sus scrofa	54.17	0.00e+00	1086.00
IUUC-Tgu-116565	Taeniopygia guttata	42.50	0.00e+00	695.00
IUUC-Tru-118742	Takifugu rubripes	52.98	0.00e+00	1006.00
IUUC-Tsy-119436	Tarsius syrichta	37.47	2.00e-162	564.00
IUUC-Tni-120401	Tetraodon nigroviridis	53.53	0.00e+00	1017.00
IUUC-Tca-121436	Theobroma cacao	48.05	0.00e+00	896.00
IUUC-Tvi-122259	Trichoderma virens	93.22	0.00e+00	1902.00
IUUC-Tae-125676	Triticum aestivum	46.52	0.00e+00	890.00
IUUC-Tur-126189	Triticum urartu	46.73	0.00e+00	827.00
IUUC-Tme-127055	Tuber melanosporum	63.12	0.00e+00	1254.00
IUUC-Tbe-127587	Tupaia belangeri	43.31	4.00e-158	550.00
IUUC-Ttr-128331	Tursiops truncatus	54.02	0.00e+00	1073.00
IUUC-Uma-129387	Ustilago maydis	57.49	0.00e+00	1129.00
IUUC-Vda-129977	Verticillium dahliae	79.23	0.00e+00	1618.00
IUUC-Vpa-130716	Vicugna pacos	41.21	0.00e+00	662.00
IUUC-Vvi-130857	Vitis vinifera	47.02	0.00e+00	894.00
IUUC-Xtr-132947	Xenopus tropicalis	38.08	0.00e+00	632.00
IUUC-Xma-133805	Xiphophorus maculatus	53.87	0.00e+00	1043.00
IUUC-Yli-134547	Yarrowia lipolytica	60.78	0.00e+00	1243.00
IUUC-Zma-135052	Zea mays	47.12	0.00e+00	884.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence