iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074350

Ensembl Protein ID

ENSOCUP00000011750.2

UniProt Accession

G1T5V4; G1T5V4_RABIT

Protein Name

Uncharacterized protein

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013657.3	ENSOCUT00000013654.2	ENSOCUP00000011750.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-15	55.9	23	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFvekl 62
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g + ++g+ G+fP+n+v+ +
   Q: 23   TAVFDYEAVGDEELTLRRGDRVQVLSQDcavSGDEGWWTG-RLASGRVGVFPSNYVAPA 80
           589**********************77622257*******.59*************875 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MEEEEGAAAA KEWGATPAGP VWTAVFDYEA VGDEELTLRR GDRVQVLSQD CAVSGDEGWW 60
TGRLASGRVG VFPSNYVAPA APAAPAGLQL PQEIPFHELQ LEEIIGVGGF GKVYRALWRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGGAAGGGGC GGCGGCGGCC AAGGAGTGGG GCGCGACCCC CGCGGGGCCC 60
GTCTGGACCG CGGTGTTCGA CTACGAGGCG GTGGGCGACG AGGAGCTGAC CCTGCGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR016231--MLK1/MLK2/MLK4
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043507--P:positive regulation of JUN kinase activity
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	92.21	0.00e+00	964.00
IUUC-Atr-002967	Amborella trichopoda	31.62	4.00e-24	105.00
IUUC-Aca-004768	Anolis carolinensis	70.50	0.00e+00	798.00
IUUC-Aly-006459	Arabidopsis lyrata	33.10	5.00e-29	122.00
IUUC-Ath-006581	Arabidopsis thaliana	32.74	2.00e-28	120.00
IUUC-Bta-013545	Bos taurus	97.20	0.00e+00	821.00
IUUC-Bdi-014449	Brachypodium distachyon	32.36	1.00e-25	111.00
IUUC-Bol-016287	Brassica oleracea	32.03	8.00e-28	119.00
IUUC-Bra-016997	Brassica rapa	33.33	6.00e-28	119.00
IUUC-Cja-019696	Callithrix jacchus	85.93	0.00e+00	1213.00
IUUC-Cfa-020789	Canis familiaris	76.86	0.00e+00	1025.00
IUUC-Cpo-021993	Cavia porcellus	76.18	0.00e+00	1102.00
IUUC-Csa-024243	Chlorocebus sabaeus	90.25	0.00e+00	1260.00
IUUC-Cho-024961	Choloepus hoffmanni	93.81	4.00e-108	385.00
IUUC-Dre-028573	Danio rerio	69.48	0.00e+00	755.00
IUUC-Dno-029095	Dasypus novemcinctus	89.39	0.00e+00	1171.00
IUUC-Dme-032210	Drosophila melanogaster	48.25	3.00e-138	486.00
IUUC-Fca-036250	Felis catus	95.80	0.00e+00	939.00
IUUC-Gmo-038497	Gadus morhua	70.92	0.00e+00	754.00
IUUC-Gac-042509	Gasterosteus aculeatus	62.93	0.00e+00	748.00
IUUC-Gma-043336	Glycine max	30.16	2.00e-26	114.00
IUUC-Ggo-045471	Gorilla gorilla	88.51	0.00e+00	868.00
IUUC-Hsa-046936	Homo sapiens	90.59	0.00e+00	1259.00
IUUC-Hvu-047798	Hordeum vulgare	33.62	5.00e-24	106.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	94.96	0.00e+00	958.00
IUUC-Lch-049935	Latimeria chalumnae	60.67	0.00e+00	934.00
IUUC-Loc-052286	Lepisosteus oculatus	67.44	0.00e+00	740.00
IUUC-Laf-053926	Loxodonta africana	63.47	0.00e+00	726.00
IUUC-Mcc-055733	Macaca mulatta	88.54	0.00e+00	1254.00
IUUC-Mtr-058733	Medicago truncatula	32.97	6.00e-27	116.00
IUUC-Mdo-062516	Monodelphis domestica	76.44	0.00e+00	920.00
IUUC-Mmu-064082	Mus musculus	88.81	0.00e+00	1332.00
IUUC-Mac-065156	Musa acuminata	31.93	9.00e-28	118.00
IUUC-Mpu-065934	Mustela putorius furo	89.27	0.00e+00	1234.00
IUUC-Mlu-068137	Myotis lucifugus	77.83	0.00e+00	1192.00
IUUC-Nle-068969	Nomascus leucogenys	63.59	0.00e+00	712.00
IUUC-Opr-070869	Ochotona princeps	76.55	0.00e+00	861.00
IUUC-Ont-072492	Oreochromis niloticus	71.43	0.00e+00	780.00
IUUC-Oba-075616	Oryza barthii	35.35	3.00e-25	110.00
IUUC-Obr-076215	Oryza brachyantha	35.38	2.00e-26	114.00
IUUC-Ogl-077159	Oryza glaberrima	35.35	3.00e-25	110.00
IUUC-Ogu-078228	Oryza glumaepatula	35.81	9.00e-26	112.00
IUUC-Oin-079079	Oryza indica	35.37	7.00e-26	112.00
IUUC-Olo-080309	Oryza longistaminata	35.55	1.00e-24	108.00
IUUC-Oni-082428	Oryza nivara	35.35	3.00e-25	110.00
IUUC-Opu-083527	Oryza punctata	35.81	2.00e-25	110.00
IUUC-Oru-084678	Oryza rufipogon	35.37	7.00e-26	112.00
IUUC-Osa-086117	Oryza sativa	35.37	7.00e-26	112.00
IUUC-Ola-087224	Oryzias latipes	61.97	0.00e+00	769.00
IUUC-Oga-088351	Otolemur garnettii	89.18	0.00e+00	1300.00
IUUC-Ptr-091607	Pan troglodytes	90.70	0.00e+00	1262.00
IUUC-Pan-092403	Papio anubis	92.04	0.00e+00	923.00
IUUC-Pfo-096104	Poecilia formosa	60.48	0.00e+00	745.00
IUUC-Pab-098396	Pongo abelii	91.39	0.00e+00	950.00
IUUC-Pop-099554	Populus trichocarpa	29.78	1.00e-24	108.00
IUUC-Pca-100945	Procavia capensis	57.07	2.00e-173	602.00
IUUC-Ppe-101208	Prunus persica	32.63	7.00e-27	115.00
IUUC-Rno-105688	Rattus norvegicus	88.91	0.00e+00	1343.00
IUUC-Smo-109113	Selaginella moellendorffii	33.09	3.00e-26	112.00
IUUC-Sit-110427	Setaria italica	35.05	2.00e-25	111.00
IUUC-Sly-111528	Solanum lycopersicum	31.03	8.00e-26	112.00
IUUC-Stu-112224	Solanum tuberosum	34.65	8.00e-25	108.00
IUUC-Sbi-113963	Sorghum bicolor	35.51	4.00e-26	113.00
IUUC-Ssc-115332	Sus scrofa	94.62	0.00e+00	955.00
IUUC-Tru-117692	Takifugu rubripes	61.82	0.00e+00	778.00
IUUC-Tsy-119412	Tarsius syrichta	91.18	4.00e-64	239.00
IUUC-Tni-120689	Tetraodon nigroviridis	60.82	0.00e+00	766.00
IUUC-Tca-121565	Theobroma cacao	34.91	2.00e-25	111.00
IUUC-Tae-125555	Triticum aestivum	32.10	2.00e-24	107.00
IUUC-Tur-126322	Triticum urartu	32.26	6.00e-25	108.00
IUUC-Tbe-127643	Tupaia belangeri	96.79	0.00e+00	652.00
IUUC-Ttr-128550	Tursiops truncatus	90.23	0.00e+00	1272.00
IUUC-Vvi-131372	Vitis vinifera	32.62	2.00e-23	104.00
IUUC-Xtr-132108	Xenopus tropicalis	61.28	0.00e+00	945.00
IUUC-Xma-134254	Xiphophorus maculatus	61.07	0.00e+00	756.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence