iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045303

Ensembl Protein ID

ENSGGOP00000008876.2

UniProt Accession

G3R126; G3R126_GORGO

Protein Name

Non-specific serine/threonine protein kinase

Gene Name

PRKAA2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000009076.2	ENSGGOT00000009119.2	ENSGGOP00000008876.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	48.07	5.00e-124	442.00	IUUC-Ath-007014

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60
IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEMEARRLF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGCGGCT ACGCGGAGCG GCAGGCGGCG GAGCGAGGCC GCGCGCGCCG AAGATGGCTG 60
AGAAGCAGAA GCACGACGGG CGGGTGAAGA TCGGACACTA CGTGCTGGGC GACACGCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF16579--AdenylateSensor
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0016607--C:nuclear speck
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0003682--F:chromatin binding
GO:0035174--F:histone serine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0035690--P:cellular response to drug
GO:0042149--P:cellular response to glucose starvation
GO:0071380--P:cellular response to prostaglandin E stimulus
GO:0042593--P:glucose homeostasis
GO:0008610--P:lipid biosynthetic process
GO:0043066--P:negative regulation of apoptotic process
GO:0032007--P:negative regulation of TOR signaling
GO:0010508--P:positive regulation of autophagy
GO:0042752--P:regulation of circadian rhythm
GO:0010468--P:regulation of gene expression
GO:0016241--P:regulation of macroautophagy
GO:0014850--P:response to muscle activity

KEGG

ggo:101137882

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000713	Aegilops tauschii	47.73	3.00e-122	432.00
IUUC-Apl-003395	Anas platyrhynchos	93.49	0.00e+00	1021.00
IUUC-Aca-004480	Anolis carolinensis	93.92	0.00e+00	1029.00
IUUC-Aly-006289	Arabidopsis lyrata	47.96	2.00e-125	442.00
IUUC-Ath-007014	Arabidopsis thaliana	48.07	1.00e-125	443.00
IUUC-Ago-007957	Ashbya gossypii	42.62	1.00e-115	410.00
IUUC-Acl-008103	Aspergillus clavatus	60.07	3.00e-101	362.00
IUUC-Afl-008555	Aspergillus flavus	59.71	1.00e-101	364.00
IUUC-Afu-008949	Aspergillus fumigatus	60.07	2.00e-101	363.00
IUUC-Ani-009408	Aspergillus nidulans	62.17	1.00e-101	363.00
IUUC-Ang-009551	Aspergillus niger	60.07	3.00e-101	362.00
IUUC-Aor-010176	Aspergillus oryzae	59.71	1.00e-101	364.00
IUUC-Ate-010287	Aspergillus terreus	60.07	5.00e-101	362.00
IUUC-Ame-011019	Astyanax mexicanus	86.27	0.00e+00	1011.00
IUUC-Bgr-012045	Blumeria graminis	61.80	2.00e-102	366.00
IUUC-Bci-013774	Botrytis cinerea	46.84	1.00e-104	374.00
IUUC-Bdi-014319	Brachypodium distachyon	46.94	8.00e-125	440.00
IUUC-Bol-016242	Brassica oleracea	48.25	3.00e-128	451.00
IUUC-Bra-016750	Brassica rapa	48.25	2.00e-128	452.00
IUUC-Cel-018518	Caenorhabditis elegans	58.09	0.00e+00	628.00
IUUC-Cja-019386	Callithrix jacchus	99.64	0.00e+00	1110.00
IUUC-Cpo-021805	Cavia porcellus	99.09	0.00e+00	1104.00
IUUC-Cre-022915	Chlamydomonas reinhardtii	54.83	1.00e-96	345.00
IUUC-Csa-024267	Chlorocebus sabaeus	99.82	0.00e+00	1095.00
IUUC-Cin-025550	Ciona intestinalis	62.16	0.00e+00	677.00
IUUC-Csv-026139	Ciona savignyi	60.33	0.00e+00	676.00
IUUC-Cne-027044	Cryptococcus neoformans	51.15	2.00e-108	386.00
IUUC-Dor-030578	Dipodomys ordii	98.55	0.00e+00	1103.00
IUUC-Dse-031507	Dothistroma septosporum	62.69	8.00e-105	374.00
IUUC-Dme-031704	Drosophila melanogaster	60.41	0.00e+00	665.00
IUUC-Eca-034016	Equus caballus	98.08	0.00e+00	1032.00
IUUC-Fox-038073	Fusarium oxysporum	51.62	9.00e-106	377.00
IUUC-Fso-038236	Fusarium solani	51.24	5.00e-102	365.00
IUUC-Ggr-039987	Gaeumannomyces graminis	48.77	5.00e-102	365.00
IUUC-Gga-040546	Gallus gallus	92.04	0.00e+00	1056.00
IUUC-Gac-041822	Gasterosteus aculeatus	83.99	0.00e+00	950.00
IUUC-Gma-042712	Glycine max	47.07	4.00e-125	441.00
IUUC-Hsa-045746	Homo sapiens	100.00	0.00e+00	1115.00
IUUC-Hvu-047406	Hordeum vulgare	47.65	3.00e-125	441.00
IUUC-Itr-048134	Ictidomys tridecemlineatus	99.46	0.00e+00	1111.00
IUUC-Kpa-049190	Komagataella pastoris	44.86	4.00e-122	431.00
IUUC-Loc-052928	Lepisosteus oculatus	90.24	0.00e+00	1033.00
IUUC-Lma-053054	Leptosphaeria maculans	62.92	3.00e-106	379.00
IUUC-Laf-053459	Loxodonta africana	98.37	0.00e+00	1101.00
IUUC-Mcc-055862	Macaca mulatta	100.00	0.00e+00	1115.00
IUUC-Mpo-057302	Magnaporthe poae	49.18	2.00e-102	366.00
IUUC-Mla-059058	Melampsora laricipopulina	43.09	2.00e-104	373.00
IUUC-Mga-059206	Meleagris gallopavo	91.55	0.00e+00	996.00
IUUC-Mvi-060337	Microbotryum violaceum	42.03	1.00e-108	387.00
IUUC-Mmr-061619	Microcebus murinus	98.37	0.00e+00	1090.00
IUUC-Mdo-062160	Monodelphis domestica	93.66	0.00e+00	1072.00
IUUC-Mmu-063406	Mus musculus	97.83	0.00e+00	1090.00
IUUC-Mac-064518	Musa acuminata	45.54	1.00e-121	429.00
IUUC-Mpu-066326	Mustela putorius furo	99.04	0.00e+00	1043.00
IUUC-Mlu-067968	Myotis lucifugus	97.16	0.00e+00	1006.00
IUUC-Nfi-068493	Neosartorya fischeri	60.07	2.00e-101	363.00
IUUC-Ncr-068665	Neurospora crassa	40.51	1.00e-106	380.00
IUUC-Nle-070158	Nomascus leucogenys	99.82	0.00e+00	1113.00
IUUC-Ont-071395	Oreochromis niloticus	86.20	0.00e+00	993.00
IUUC-Oba-075436	Oryza barthii	47.44	1.00e-126	446.00
IUUC-Ogl-077718	Oryza glaberrima	50.34	8.00e-124	437.00
IUUC-Ogu-078349	Oryza glumaepatula	47.11	1.00e-126	446.00
IUUC-Oin-079889	Oryza indica	46.00	2.00e-124	438.00
IUUC-Olo-080521	Oryza longistaminata	47.44	2.00e-126	446.00
IUUC-Oru-084252	Oryza rufipogon	47.44	1.00e-126	446.00
IUUC-Osa-085548	Oryza sativa	47.44	1.00e-126	446.00
IUUC-Ola-087169	Oryzias latipes	84.41	0.00e+00	967.00
IUUC-Ptr-090741	Pan troglodytes	100.00	0.00e+00	1115.00
IUUC-Pno-095030	Phaeosphaeria nodorum	62.92	2.00e-104	372.00
IUUC-Ppa-095615	Physcomitrella patens	45.28	7.00e-124	437.00
IUUC-Pfo-096295	Poecilia formosa	85.30	0.00e+00	980.00
IUUC-Pab-098023	Pongo abelii	100.00	0.00e+00	1115.00
IUUC-Pop-100042	Populus trichocarpa	47.98	3.00e-128	451.00
IUUC-Ppe-101642	Prunus persica	48.95	2.00e-125	442.00
IUUC-Pva-102470	Pteropus vampyrus	98.19	0.00e+00	1092.00
IUUC-Pgr-103406	Puccinia graminis	61.36	5.00e-92	332.00
IUUC-Ptt-103713	Puccinia triticina	37.85	5.00e-79	288.00
IUUC-Pte-104259	Pyrenophora teres	62.55	2.00e-105	376.00
IUUC-Pyt-104752	Pyrenophora triticirepentis	62.92	6.00e-106	378.00
IUUC-Rno-104960	Rattus norvegicus	98.37	0.00e+00	1102.00
IUUC-Sce-106290	Saccharomyces cerevisiae	42.46	2.00e-116	413.00
IUUC-Sja-107772	Schizosaccharomyces japonicus	40.53	1.00e-110	393.00
IUUC-Ssl-108535	Sclerotinia sclerotiorum	46.34	2.00e-103	370.00
IUUC-Sly-110890	Solanum lycopersicum	48.28	1.00e-126	446.00
IUUC-Stu-112144	Solanum tuberosum	46.23	5.00e-119	421.00
IUUC-Sre-115141	Sporisorium reilianum	66.91	2.00e-115	410.00
IUUC-Tru-118735	Takifugu rubripes	84.59	0.00e+00	979.00
IUUC-Tsy-119503	Tarsius syrichta	95.96	0.00e+00	988.00
IUUC-Tni-119880	Tetraodon nigroviridis	84.79	0.00e+00	979.00
IUUC-Tca-121386	Theobroma cacao	47.46	3.00e-127	448.00
IUUC-Tvi-122305	Trichoderma virens	49.46	3.00e-102	365.00
IUUC-Tae-123515	Triticum aestivum	47.75	2.00e-126	445.00
IUUC-Tur-126416	Triticum urartu	47.55	1.00e-123	436.00
IUUC-Tbe-127791	Tupaia belangeri	86.09	1.00e-113	402.00
IUUC-Uma-129372	Ustilago maydis	66.91	1.00e-114	407.00
IUUC-Vda-129819	Verticillium dahliae	53.68	2.00e-86	313.00
IUUC-Vpa-130220	Vicugna pacos	98.27	0.00e+00	1030.00
IUUC-Vvi-131649	Vitis vinifera	47.97	8.00e-126	443.00
IUUC-Xtr-132954	Xenopus tropicalis	92.41	0.00e+00	1066.00
IUUC-Xma-134119	Xiphophorus maculatus	85.13	0.00e+00	978.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence