iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132797

Ensembl Protein ID

ENSXETP00000046423.3

UniProt Accession

F6ZNB9; F6ZNB9_XENTR

Genbank Protein ID

ENSXETP00000046423

Protein Name

Rho guanine nucleotide exchange factor 15

Genbank Nucleotide ID

AAMC01149182

Gene Name

arhgef15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000021474.4	ENSXETT00000046423.3	ENSXETP00000046423.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.40e-11	42.0	282	338

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +vq + +y+a++ deL+l+  d++ v+  ++++egW +g +   gk+G fP+ +v+++ 
   Q: 282  QVQCIEPYSASQADELNLEPVDIINVL--KKTSEGWYEGIRLSDGKKGWFPSLYVQEIT 338
           5788889********************..99************************9985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

RFLMDLEDRV EENIIITDVC DIIYAHSRHH FPVYIDYVRN QVFQEKTYSE LLEKNPQFHA 60
ALCRLQDLPQ CHRLPFMSFL LLPFQRITRI KMLIETPLLA LHPLTALSIT TSHTHPXSTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTTCCTCA TGGATTTGGA GGATCGAGTA GAGGAAAATA TCATCATCAC CGACGTGTGT 60
GACATCATCT ACGCGCACTC GCGCCATCAC TTCCCCGTGT ACATCGACTA CGTGCGCAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00621--RhoGEF
PF14604--SH3_9

SMART

SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005169	Anolis carolinensis	60.23	1.00e-121	430.00
IUUC-Bta-013108	Bos taurus	42.86	8.00e-76	277.00
IUUC-Cin-025559	Ciona intestinalis	46.15	4.00e-25	106.00
IUUC-Eca-033839	Equus caballus	42.86	1.00e-75	277.00
IUUC-Lch-049409	Latimeria chalumnae	60.06	8.00e-110	390.00
IUUC-Mvi-060551	Microbotryum violaceum	40.00	3.00e-07	52.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence