iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026253

UUCD1 version

UUC-CiS-00472

Ensembl Protein ID

ENSCSAVP00000017106.1

UniProt Accession

H2ZHP0; H2ZHP0_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000010058.1	ENSCSAVT00000017289.1	ENSCSAVP00000017106.1
ENSCSAVG00000010058.1	ENSCSAVT00000017290.1	ENSCSAVP00000017107.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-94	316.4	706	1032

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +Gl+NlgN+CYmNSvLQc++n+++l+e++l+ +++++ln+ n  ++ g++++s+  l++++w+sk + + p++++ +++++++ f 
   Q: 706  CGLRNLGNSCYMNSVLQCMFNMTQLAEYILSnSYTRDLNRVNAIGHGGKVAESFSVLLRAVWSSKYEFIVPSDFKYIIGNINPIFA 791
           7******************************99***************************************************** PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssre 166
           g  q+D+qEfl+ lld+l+e+l+k + ++++ee ++d    +d+     a++ +k++n+s+i++l++gq+k ++kcl+c++vs ++
   Q: 792  GLTQEDSQEFLMLLLDGLHEDLNKASPSEYKEEPDNDAL--DDDeaaklAWKYHKRRNESIIVELLKGQFKATVKCLHCGKVSRKF 875
           **********************99999999999888844..44445888************************************* PP
   S: 167  epfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkk 252
           +pf+ lslp+p+k++    s+ d+L+sf k e+++g+++++c++ck +++a++++ ++klP+vLi+h+kRf   +++  r ki+++
   Q: 876  DPFMFLSLPLPQKSS----SVYDILNSFQKVEKMTGSDRWHCPSCKTLRDAVRSIVIWKLPPVLIIHFKRF--VHTGRWRDKIHTN 955
           **************6....8***************************************************..45556677***** PP
   S: 253  vefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
           +++p++ Ldl++f +s++    ++ kY+L+av  H+G +l+sGHY+a +k+  +++W++fdD++V  ++  +       ta +lfY
   Q: 956  ISYPISqLDLNRFISSSQ----KRPKYDLFAVSHHQGaGLDSGHYTASCKSvLDNNWYKFDDTEVMRTSAPQ--G---PTASILFY 1032
           ****999********944....389**************************66777*********9986433..3...55777777 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

VMDFPRDLYI AKSLKELNKH ANCDSDTGRS VKSQLTFANK AFGEAEKAFK NFDEERAYIL 60
YMKYLDLVGK IRKSSEFKKD PKHYSLLLGK VSIDKALTNA EKTSVSLKKR YNALVNKSNE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTAATGGATT TTCCAAGGGA TCTATACATT GCGAAATCTT TAAAGGAGCT CAATAAGCAT 60
GCAAACTGTG ATTCAGATAC AGGCCGCAGT GTGAAATCTC AATTGACTTT TGCGAATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF08969--USP8_dimer

SMART

SM00450--RHOD

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	48.53	1.00e-111	395.00
IUUC-Apl-003226	Anas platyrhynchos	49.12	1.00e-111	395.00
IUUC-Aca-004936	Anolis carolinensis	48.75	5.00e-104	370.00
IUUC-Ago-007959	Ashbya gossypii	32.23	7.00e-50	190.00
IUUC-Acl-008102	Aspergillus clavatus	30.68	5.00e-50	191.00
IUUC-Afl-008604	Aspergillus flavus	31.86	1.00e-50	192.00
IUUC-Afu-009001	Aspergillus fumigatus	31.04	2.00e-50	193.00
IUUC-Ani-009291	Aspergillus nidulans	28.96	9.00e-49	187.00
IUUC-Ang-009844	Aspergillus niger	30.38	2.00e-50	192.00
IUUC-Aor-010098	Aspergillus oryzae	31.37	2.00e-50	192.00
IUUC-Ate-010585	Aspergillus terreus	30.27	4.00e-49	188.00
IUUC-Bta-013008	Bos taurus	48.41	2.00e-111	395.00
IUUC-Bra-017228	Brassica rapa	34.82	3.00e-43	167.00
IUUC-Cel-018482	Caenorhabditis elegans	32.41	1.00e-47	182.00
IUUC-Cja-019173	Callithrix jacchus	47.56	5.00e-111	394.00
IUUC-Cfa-021243	Canis familiaris	48.53	1.00e-111	396.00
IUUC-Cpo-021522	Cavia porcellus	47.65	7.00e-111	393.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	40.17	3.00e-73	266.00
IUUC-Csa-023616	Chlorocebus sabaeus	47.78	3.00e-109	388.00
IUUC-Cho-024381	Choloepus hoffmanni	43.28	3.00e-83	302.00
IUUC-Cin-025287	Ciona intestinalis	64.57	0.00e+00	1110.00
IUUC-Cne-026821	Cryptococcus neoformans	38.80	2.00e-71	262.00
IUUC-Dre-028440	Danio rerio	46.53	3.00e-104	371.00
IUUC-Dno-029039	Dasypus novemcinctus	48.03	6.00e-111	394.00
IUUC-Dor-031043	Dipodomys ordii	50.46	1.00e-60	226.00
IUUC-Dse-031463	Dothistroma septosporum	28.57	4.00e-42	165.00
IUUC-Dme-032089	Drosophila melanogaster	39.65	2.00e-68	252.00
IUUC-Ete-033040	Echinops telfairi	49.51	5.00e-86	310.00
IUUC-Eca-033449	Equus caballus	48.53	4.00e-113	401.00
IUUC-Eeu-034693	Erinaceus europaeus	48.61	1.00e-57	217.00
IUUC-Fca-035794	Felis catus	48.53	5.00e-109	386.00
IUUC-Fal-037322	Ficedula albicollis	49.63	1.00e-111	396.00
IUUC-Gmo-038584	Gadus morhua	45.21	2.00e-98	352.00
IUUC-Gga-041188	Gallus gallus	49.12	8.00e-112	396.00
IUUC-Gac-041850	Gasterosteus aculeatus	47.64	6.00e-103	367.00
IUUC-Ggo-045565	Gorilla gorilla	48.03	5.00e-111	394.00
IUUC-Hsa-046438	Homo sapiens	48.03	4.00e-111	394.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	48.03	4.00e-111	394.00
IUUC-Kpa-049321	Komagataella pastoris	32.60	3.00e-50	191.00
IUUC-Lch-050485	Latimeria chalumnae	47.56	9.00e-110	390.00
IUUC-Loc-052769	Lepisosteus oculatus	46.36	1.00e-102	366.00
IUUC-Laf-053432	Loxodonta africana	48.16	2.00e-110	392.00
IUUC-Mcc-055823	Macaca mulatta	47.78	1.00e-110	392.00
IUUC-Meu-056099	Macropus eugenii	51.30	1.00e-83	303.00
IUUC-Mla-059089	Melampsora laricipopulina	40.06	3.00e-69	255.00
IUUC-Mga-059739	Meleagris gallopavo	49.12	4.00e-111	394.00
IUUC-Mvi-060559	Microbotryum violaceum	41.54	2.00e-72	266.00
IUUC-Mmr-061158	Microcebus murinus	48.05	4.00e-111	394.00
IUUC-Mdo-061801	Monodelphis domestica	48.16	2.00e-110	392.00
IUUC-Mmu-063665	Mus musculus	47.16	4.00e-110	391.00
IUUC-Mpu-066738	Mustela putorius furo	48.66	7.00e-112	397.00
IUUC-Mlu-067307	Myotis lucifugus	48.28	2.00e-111	395.00
IUUC-Nfi-068410	Neosartorya fischeri	31.04	3.00e-50	192.00
IUUC-Nle-069314	Nomascus leucogenys	48.03	3.00e-111	394.00
IUUC-Ont-071545	Oreochromis niloticus	45.81	9.00e-104	370.00
IUUC-Oan-073537	Ornithorhynchus anatinus	40.10	1.00e-110	392.00
IUUC-Ocu-074193	Oryctolagus cuniculus	47.90	5.00e-111	394.00
IUUC-Ola-086622	Oryzias latipes	45.54	1.00e-101	362.00
IUUC-Oga-088271	Otolemur garnettii	47.56	3.00e-110	391.00
IUUC-Oar-090431	Ovis aries	48.41	2.00e-111	395.00
IUUC-Ptr-091339	Pan troglodytes	48.16	1.00e-111	396.00
IUUC-Pan-092266	Papio anubis	48.49	2.00e-90	323.00
IUUC-Psi-093243	Pelodiscus sinensis	38.44	2.00e-57	214.00
IUUC-Pma-094626	Petromyzon marinus	45.65	8.00e-101	358.00
IUUC-Pfo-096463	Poecilia formosa	46.49	6.00e-105	374.00
IUUC-Pab-097645	Pongo abelii	48.16	3.00e-111	395.00
IUUC-Pva-103222	Pteropus vampyrus	49.01	1.00e-101	363.00
IUUC-Pgr-103408	Puccinia graminis	35.69	3.00e-51	195.00
IUUC-Ptt-103699	Puccinia triticina	41.67	4.00e-64	238.00
IUUC-Rno-105510	Rattus norvegicus	48.16	1.00e-110	393.00
IUUC-Sha-106879	Sarcophilus harrisii	47.80	2.00e-109	389.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	34.84	7.00e-51	193.00
IUUC-Spo-108065	Schizosaccharomyces pombe	34.87	2.00e-45	175.00
IUUC-Sar-113019	Sorex araneus	47.79	4.00e-109	387.00
IUUC-Sre-115031	Sporisorium reilianum	38.37	2.00e-70	259.00
IUUC-Ssc-116334	Sus scrofa	48.28	2.00e-111	395.00
IUUC-Tgu-117062	Taeniopygia guttata	49.63	1.00e-111	396.00
IUUC-Tru-117908	Takifugu rubripes	47.04	3.00e-105	375.00
IUUC-Tsy-118867	Tarsius syrichta	42.01	8.00e-90	323.00
IUUC-Tni-120206	Tetraodon nigroviridis	46.88	9.00e-100	356.00
IUUC-Tme-127144	Tuber melanosporum	38.05	2.00e-71	263.00
IUUC-Tbe-127877	Tupaia belangeri	45.83	4.00e-35	142.00
IUUC-Ttr-128580	Tursiops truncatus	47.65	2.00e-111	395.00
IUUC-Uma-129340	Ustilago maydis	38.19	2.00e-69	256.00
IUUC-Vpa-130541	Vicugna pacos	47.54	7.00e-110	390.00
IUUC-Xtr-132161	Xenopus tropicalis	48.03	1.00e-111	395.00
IUUC-Xma-134271	Xiphophorus maculatus	46.25	7.00e-105	373.00
IUUC-Yli-134561	Yarrowia lipolytica	34.33	1.00e-58	220.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence