iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066540

Ensembl Protein ID

ENSMPUP00000013612.1

UniProt Accession

M3YQK3; M3YQK3_MUSPF

Genbank Protein ID

ENSMPUP00000013612

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01074352

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013715.1	ENSMPUT00000013829.1	ENSMPUP00000013612.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.90e-09	36.1	4	42
ULD/UDP/UFD/UBX	3.80e-20	72.3	209	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 209  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 290
           578*****************************************************************************98 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLATPLGHVL 60
GREPTSPEQG GPEGTGSAAG EGKPILSEEE RQEQTKRMLE LVAQKQRERE EREEREALER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAGC TGACGGCTCT GGAGAGTCTC ATCGAGATGG GCTTCCCCAG GGGACGCGCG 60
TAAGGCAGCC CCTCAAACCT TGGCCCGCGG GGATCGCGGA CCTGACTGGC CTTTCCCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	98.63	8.00e-117	412.00
IUUC-Aca-004329	Anolis carolinensis	73.10	2.00e-50	191.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	1.00e-11	64.30
IUUC-Ath-006887	Arabidopsis thaliana	50.91	2.00e-11	63.50
IUUC-Ago-007989	Ashbya gossypii	37.18	7.00e-07	47.80
IUUC-Ame-011399	Astyanax mexicanus	52.90	2.00e-65	241.00
IUUC-Bta-013151	Bos taurus	94.26	3.00e-125	441.00
IUUC-Bol-016537	Brassica oleracea	50.91	2.00e-11	63.50
IUUC-Bra-017906	Brassica rapa	59.09	3.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	35.11	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	93.66	1.00e-102	365.00
IUUC-Cfa-020997	Canis familiaris	94.70	3.00e-92	331.00
IUUC-Cpo-021736	Cavia porcellus	80.47	5.00e-83	300.00
IUUC-Csa-024040	Chlorocebus sabaeus	92.59	1.00e-102	365.00
IUUC-Cho-024543	Choloepus hoffmanni	96.53	1.00e-72	265.00
IUUC-Cin-025719	Ciona intestinalis	40.34	7.00e-40	157.00
IUUC-Csv-025854	Ciona savignyi	38.80	5.00e-39	154.00
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	3.00e-08	52.80
IUUC-Dre-027745	Danio rerio	51.84	1.00e-61	229.00
IUUC-Dno-029598	Dasypus novemcinctus	90.54	6.00e-105	373.00
IUUC-Dor-030917	Dipodomys ordii	78.52	2.00e-88	318.00
IUUC-Dme-032055	Drosophila melanogaster	42.94	1.00e-24	107.00
IUUC-Ete-032960	Echinops telfairi	76.87	5.00e-78	283.00
IUUC-Eca-034294	Equus caballus	95.61	5.00e-115	407.00
IUUC-Eeu-034906	Erinaceus europaeus	91.23	4.00e-106	377.00
IUUC-Fca-035653	Felis catus	96.82	1.00e-98	352.00
IUUC-Gmo-038755	Gadus morhua	50.96	3.00e-58	218.00
IUUC-Gac-042481	Gasterosteus aculeatus	54.19	2.00e-58	218.00
IUUC-Ggo-044821	Gorilla gorilla	90.85	1.00e-95	342.00
IUUC-Hsa-046797	Homo sapiens	91.58	7.00e-104	369.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	92.59	9.00e-114	402.00
IUUC-Lch-049508	Latimeria chalumnae	53.54	2.00e-57	215.00
IUUC-Laf-053932	Loxodonta africana	95.62	6.00e-132	463.00
IUUC-Mcc-055300	Macaca mulatta	92.93	7.00e-103	366.00
IUUC-Mtr-058774	Medicago truncatula	45.90	4.00e-10	58.50
IUUC-Mvi-060245	Microbotryum violaceum	40.48	9.00e-12	64.30
IUUC-Mmr-060979	Microcebus murinus	91.58	5.00e-108	383.00
IUUC-Mdo-062299	Monodelphis domestica	86.22	7.00e-98	349.00
IUUC-Mmu-063212	Mus musculus	93.94	3.00e-117	414.00
IUUC-Mlu-067589	Myotis lucifugus	94.59	2.00e-110	391.00
IUUC-Nle-069045	Nomascus leucogenys	91.30	2.00e-75	275.00
IUUC-Opr-070772	Ochotona princeps	88.69	5.00e-88	317.00
IUUC-Ont-072006	Oreochromis niloticus	53.18	2.00e-58	219.00
IUUC-Oan-073244	Ornithorhynchus anatinus	63.57	2.00e-48	185.00
IUUC-Ocu-074333	Oryctolagus cuniculus	90.57	3.00e-105	374.00
IUUC-Oba-075451	Oryza barthii	49.06	5.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	1.00e-11	64.30
IUUC-Ogl-077259	Oryza glaberrima	36.99	1.00e-09	57.80
IUUC-Ogu-078589	Oryza glumaepatula	49.06	5.00e-11	62.40
IUUC-Oin-079151	Oryza indica	49.06	4.00e-11	62.40
IUUC-Ome-081253	Oryza meridionalis	49.06	4.00e-11	62.40
IUUC-Oni-082110	Oryza nivara	35.63	2.00e-10	59.70
IUUC-Opu-083336	Oryza punctata	49.06	5.00e-11	62.00
IUUC-Oru-085235	Oryza rufipogon	49.06	5.00e-11	62.40
IUUC-Osa-085611	Oryza sativa	49.06	5.00e-11	62.40
IUUC-Ola-086781	Oryzias latipes	53.72	7.00e-56	210.00
IUUC-Oga-088429	Otolemur garnettii	92.26	4.00e-104	370.00
IUUC-Oar-089885	Ovis aries	93.92	2.00e-125	441.00
IUUC-Ptr-091315	Pan troglodytes	90.81	9.00e-96	343.00
IUUC-Pan-092885	Papio anubis	92.59	1.00e-102	365.00
IUUC-Psi-093299	Pelodiscus sinensis	72.73	3.00e-67	248.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	53.35	3.00e-55	208.00
IUUC-Pab-097881	Pongo abelii	85.86	8.00e-101	359.00
IUUC-Pop-098863	Populus trichocarpa	36.87	6.00e-12	65.10
IUUC-Pca-100977	Procavia capensis	92.33	1.00e-105	375.00
IUUC-Ppe-101243	Prunus persica	47.06	4.00e-10	58.90
IUUC-Pva-102169	Pteropus vampyrus	94.72	2.00e-99	355.00
IUUC-Rno-105459	Rattus norvegicus	92.59	3.00e-116	411.00
IUUC-Sha-107526	Sarcophilus harrisii	88.18	3.00e-98	351.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	25.93	4.00e-06	46.20
IUUC-Sit-110434	Setaria italica	31.52	1.00e-09	57.00
IUUC-Sar-112945	Sorex araneus	93.94	9.00e-72	263.00
IUUC-Sbi-114159	Sorghum bicolor	31.35	2.00e-10	59.70
IUUC-Ssc-116114	Sus scrofa	92.93	1.00e-102	366.00
IUUC-Tru-117839	Takifugu rubripes	53.55	1.00e-56	213.00
IUUC-Tsy-118813	Tarsius syrichta	72.89	1.00e-98	352.00
IUUC-Tni-120504	Tetraodon nigroviridis	57.43	5.00e-58	217.00
IUUC-Tbe-128034	Tupaia belangeri	93.31	1.00e-105	375.00
IUUC-Ttr-128468	Tursiops truncatus	87.84	1.00e-102	365.00
IUUC-Uma-129569	Ustilago maydis	34.62	2.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	89.18	5.00e-78	283.00
IUUC-Xtr-132119	Xenopus tropicalis	62.75	3.00e-69	254.00
IUUC-Xma-134067	Xiphophorus maculatus	53.25	9.00e-56	210.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence