iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048773

Ensembl Protein ID

ENSSTOP00000020496.1

UniProt Accession

I3N800; I3N800_ICTTR

Genbank Protein ID

ENSSTOP00000020496

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01030395

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000027506.1	ENSSTOT00000028769.1	ENSSTOP00000020496.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.40e-67	221.1	1161	1212

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy+aqnddeL + kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1161 QVIGMYDYTAQNDDELAFSKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVK 1212
           46779**********************..8889******..9*************8 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP VMKQQPVAIS SAPAFGIGGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGGAGGA GCGTAGGGAG GGAGCGCAGC TTGGTTGCTC CGTAGTACGG CGGCTCGCGA 60
GGGAGACTCC CGAGCGGGCT CCGGGACGGG CGGGCAGGCG GGCGGGGATG GTGTGCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	41.67	2.00e-14	75.10
IUUC-Aml-001218	Ailuropoda melanoleuca	92.01	0.00e+00	2298.00
IUUC-Atr-002491	Amborella trichopoda	33.58	1.00e-13	72.00
IUUC-Apl-003335	Anas platyrhynchos	87.98	0.00e+00	2174.00
IUUC-Aca-005130	Anolis carolinensis	85.47	0.00e+00	2132.00
IUUC-Ago-007935	Ashbya gossypii	34.59	2.00e-14	73.90
IUUC-Acl-008295	Aspergillus clavatus	30.46	7.00e-16	79.00
IUUC-Ang-009722	Aspergillus niger	31.45	2.00e-16	80.90
IUUC-Ate-010587	Aspergillus terreus	32.90	3.00e-17	84.00
IUUC-Ame-011878	Astyanax mexicanus	72.15	0.00e+00	1809.00
IUUC-Bta-012863	Bos taurus	91.69	0.00e+00	2240.00
IUUC-Bdi-014016	Brachypodium distachyon	28.50	2.00e-14	74.70
IUUC-Bol-015187	Brassica oleracea	37.66	6.00e-11	62.80
IUUC-Cja-019012	Callithrix jacchus	93.91	0.00e+00	2302.00
IUUC-Cfa-020272	Canis familiaris	92.25	0.00e+00	2313.00
IUUC-Cpo-021352	Cavia porcellus	86.65	0.00e+00	2789.00
IUUC-Csa-023122	Chlorocebus sabaeus	61.50	0.00e+00	1186.00
IUUC-Cho-024969	Choloepus hoffmanni	81.79	0.00e+00	1816.00
IUUC-Cin-025435	Ciona intestinalis	43.52	0.00e+00	908.00
IUUC-Csv-026290	Ciona savignyi	53.33	0.00e+00	687.00
IUUC-Cne-026918	Cryptococcus neoformans	31.90	1.00e-32	136.00
IUUC-Dre-028623	Danio rerio	72.60	0.00e+00	1824.00
IUUC-Dno-030044	Dasypus novemcinctus	92.44	0.00e+00	2296.00
IUUC-Dor-030272	Dipodomys ordii	85.70	0.00e+00	2000.00
IUUC-Ete-032927	Echinops telfairi	86.75	0.00e+00	976.00
IUUC-Eca-033469	Equus caballus	92.72	0.00e+00	2270.00
IUUC-Eeu-034977	Erinaceus europaeus	92.87	0.00e+00	1148.00
IUUC-Fca-036419	Felis catus	91.77	0.00e+00	2255.00
IUUC-Fal-037236	Ficedula albicollis	86.18	0.00e+00	2156.00
IUUC-Gmo-039632	Gadus morhua	66.90	0.00e+00	1565.00
IUUC-Gga-040835	Gallus gallus	86.22	0.00e+00	2135.00
IUUC-Gac-041948	Gasterosteus aculeatus	68.43	0.00e+00	1695.00
IUUC-Ggo-045100	Gorilla gorilla	89.52	0.00e+00	1959.00
IUUC-Hsa-045699	Homo sapiens	94.38	0.00e+00	2367.00
IUUC-Hvu-047530	Hordeum vulgare	33.14	1.00e-14	75.10
IUUC-Kpa-049215	Komagataella pastoris	39.29	5.00e-15	75.90
IUUC-Lch-050502	Latimeria chalumnae	73.99	0.00e+00	1526.00
IUUC-Lpe-051250	Leersia perrieri	41.67	2.00e-14	74.70
IUUC-Loc-052613	Lepisosteus oculatus	77.01	0.00e+00	1849.00
IUUC-Laf-053608	Loxodonta africana	90.87	0.00e+00	2286.00
IUUC-Mcc-055720	Macaca mulatta	93.75	0.00e+00	2321.00
IUUC-Meu-056445	Macropus eugenii	80.46	0.00e+00	1586.00
IUUC-Mla-059128	Melampsora laricipopulina	30.55	9.00e-31	130.00
IUUC-Mga-059997	Meleagris gallopavo	55.88	0.00e+00	1355.00
IUUC-Mvi-060268	Microbotryum violaceum	28.61	6.00e-35	143.00
IUUC-Mmr-061258	Microcebus murinus	93.20	0.00e+00	2285.00
IUUC-Mdo-062019	Monodelphis domestica	88.54	0.00e+00	2126.00
IUUC-Mmu-063885	Mus musculus	91.14	0.00e+00	2321.00
IUUC-Mpu-066431	Mustela putorius furo	61.46	0.00e+00	1196.00
IUUC-Mlu-068190	Myotis lucifugus	61.03	0.00e+00	1204.00
IUUC-Nle-069448	Nomascus leucogenys	88.17	0.00e+00	1250.00
IUUC-Opr-070441	Ochotona princeps	86.78	0.00e+00	1991.00
IUUC-Ont-071752	Oreochromis niloticus	69.49	0.00e+00	1692.00
IUUC-Oan-073390	Ornithorhynchus anatinus	84.75	0.00e+00	2069.00
IUUC-Ocu-073753	Oryctolagus cuniculus	91.47	0.00e+00	2928.00
IUUC-Ogu-078849	Oryza glumaepatula	41.67	2.00e-14	74.70
IUUC-Olo-080259	Oryza longistaminata	41.67	2.00e-14	75.10
IUUC-Ome-081199	Oryza meridionalis	41.67	2.00e-14	75.10
IUUC-Oni-082167	Oryza nivara	41.67	4.00e-14	73.90
IUUC-Oru-084541	Oryza rufipogon	41.67	4.00e-14	73.90
IUUC-Ola-087489	Oryzias latipes	43.99	0.00e+00	1147.00
IUUC-Olu-087698	Ostreococcus lucimarinus	27.71	3.00e-17	83.20
IUUC-Oga-088602	Otolemur garnettii	92.96	0.00e+00	2291.00
IUUC-Oar-090195	Ovis aries	92.01	0.00e+00	2256.00
IUUC-Ptr-091363	Pan troglodytes	94.46	0.00e+00	2370.00
IUUC-Pan-092385	Papio anubis	94.23	0.00e+00	2345.00
IUUC-Psi-093551	Pelodiscus sinensis	88.30	0.00e+00	1277.00
IUUC-Pfo-097486	Poecilia formosa	70.85	0.00e+00	1731.00
IUUC-Pab-098281	Pongo abelii	83.16	0.00e+00	1979.00
IUUC-Pca-100270	Procavia capensis	75.10	0.00e+00	1239.00
IUUC-Pva-102335	Pteropus vampyrus	89.57	0.00e+00	2229.00
IUUC-Pgr-103473	Puccinia graminis	27.99	3.00e-29	125.00
IUUC-Ptt-103973	Puccinia triticina	23.32	2.00e-19	92.40
IUUC-Rno-106122	Rattus norvegicus	90.14	0.00e+00	2281.00
IUUC-Sha-106851	Sarcophilus harrisii	89.00	0.00e+00	2146.00
IUUC-Smo-108995	Selaginella moellendorffii	36.62	3.00e-08	52.80
IUUC-Sit-110414	Setaria italica	40.48	2.00e-14	74.30
IUUC-Sbi-114170	Sorghum bicolor	40.00	7.00e-15	76.30
IUUC-Sre-115028	Sporisorium reilianum	34.76	9.00e-26	113.00
IUUC-Ssc-116237	Sus scrofa	92.98	0.00e+00	1266.00
IUUC-Tgu-117028	Taeniopygia guttata	86.82	0.00e+00	2189.00
IUUC-Tru-117789	Takifugu rubripes	72.48	0.00e+00	1744.00
IUUC-Tsy-119039	Tarsius syrichta	90.56	0.00e+00	1340.00
IUUC-Tni-119952	Tetraodon nigroviridis	69.95	0.00e+00	1617.00
IUUC-Tae-123242	Triticum aestivum	41.67	3.00e-14	73.90
IUUC-Tur-126623	Triticum urartu	41.67	3.00e-14	73.90
IUUC-Tbe-127754	Tupaia belangeri	86.27	0.00e+00	1766.00
IUUC-Ttr-129178	Tursiops truncatus	92.72	0.00e+00	2278.00
IUUC-Uma-129456	Ustilago maydis	30.77	2.00e-24	109.00
IUUC-Vpa-130687	Vicugna pacos	92.96	0.00e+00	1205.00
IUUC-Xtr-132905	Xenopus tropicalis	82.14	0.00e+00	2055.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence