iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066596

Ensembl Protein ID

ENSMPUP00000008697.1

UniProt Accession

M3YBJ0; M3YBJ0_MUSPF

Genbank Protein ID

ENSMPUP00000008697

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01028220

Gene Name

VPS18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008768.1	ENSMPUT00000008840.1	ENSMPUP00000008697.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.20e-06	26.5	853	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp......CgHvfhadCl.qkw.pglknssskefr........................................ 41
           Ca+C  df   pl+++      CgH+fhadCl q++ pgl+  ++k++r                                        
   Q: 853  CATC--DF---PLLNRpfylflCGHMFHADCLlQAVrPGLP--AYKQARleelqrklgaapapakgstrtkeaeagaaaagpsreqlka 934
           9***..99...66555666668*********9788887777..8888877777777777777778888888888888888888888888 PP
   S: 42   .........CPlC 45
                    C++C
   Q: 935  dldelvaaeCVYC 947
           8888888888887 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MASILDEYED SLSRSAVLQP GCPSVGIPHS GYVNAQLEKE VPIFTKQRID FTPSERITSL 60
VVSCNQLCMS LGKDTLLRID LGKANEPNHV ELGRKDDAKV HKMFLDHTGS HLLIALSSTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNCAGGCCCT GCGCGAGTAA ACGCTGGGCT CCAAGAACGG AAGTTACGTT ATAGGCGCGC 60
GTCCCGGGGG CGGGAGTCAG CTGAGCTGCC GGGGCGAGGT TGGGATCTTC TCGAATCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000547--Clathrin_H-chain/VPS_repeat
IPR007810--Pep3_Vps18
IPR011990--TPR-like_helical_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50236--CHCR

Pfam

PF00637--Clathrin
PF05131--Pep3_Vps18

Gene Ontology

GO:0005884--C:actin filament
GO:0030123--C:AP-3 adaptor complex
GO:0033263--C:CORVET complex
GO:0005769--C:early endosome
GO:0030897--C:HOPS complex
GO:0005770--C:late endosome
GO:0005765--C:lysosomal membrane
GO:0007032--P:endosome organization
GO:0008333--P:endosome to lysosome transport
GO:0006886--P:intracellular protein transport
GO:0007040--P:lysosome organization
GO:0016192--P:vesicle-mediated transport
GO:0046718--P:viral entry into host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000419	Aegilops tauschii	31.97	8.00e-108	385.00
IUUC-Aml-001240	Ailuropoda melanoleuca	98.15	0.00e+00	1900.00
IUUC-Atr-003125	Amborella trichopoda	33.23	2.00e-122	434.00
IUUC-Apl-004181	Anas platyrhynchos	72.48	0.00e+00	1477.00
IUUC-Aca-004437	Anolis carolinensis	72.38	0.00e+00	1456.00
IUUC-Aly-006046	Arabidopsis lyrata	33.70	2.00e-134	473.00
IUUC-Ath-006932	Arabidopsis thaliana	33.82	2.00e-133	469.00
IUUC-Ago-007800	Ashbya gossypii	22.77	2.00e-54	207.00
IUUC-Acl-008035	Aspergillus clavatus	31.38	3.00e-110	393.00
IUUC-Afl-008714	Aspergillus flavus	31.17	6.00e-108	385.00
IUUC-Afu-009063	Aspergillus fumigatus	32.32	2.00e-112	400.00
IUUC-Ani-009384	Aspergillus nidulans	32.28	3.00e-114	406.00
IUUC-Ang-009507	Aspergillus niger	32.22	6.00e-110	392.00
IUUC-Aor-010094	Aspergillus oryzae	31.17	2.00e-107	383.00
IUUC-Ate-010421	Aspergillus terreus	31.46	2.00e-95	343.00
IUUC-Ame-011797	Astyanax mexicanus	65.64	0.00e+00	1300.00
IUUC-Bgr-012107	Blumeria graminis	32.21	1.00e-108	387.00
IUUC-Bta-012339	Bos taurus	97.23	0.00e+00	1895.00
IUUC-Bci-013895	Botrytis cinerea	33.15	2.00e-118	420.00
IUUC-Bdi-014554	Brachypodium distachyon	33.98	2.00e-125	443.00
IUUC-Bol-015270	Brassica oleracea	33.82	3.00e-135	476.00
IUUC-Bra-017424	Brassica rapa	33.57	5.00e-130	459.00
IUUC-Cel-018455	Caenorhabditis elegans	25.76	1.00e-84	308.00
IUUC-Cja-019629	Callithrix jacchus	95.58	0.00e+00	1874.00
IUUC-Cfa-020425	Canis familiaris	97.84	0.00e+00	1887.00
IUUC-Cpo-021349	Cavia porcellus	95.38	0.00e+00	1840.00
IUUC-Cre-022799	Chlamydomonas reinhardtii	29.52	1.00e-26	115.00
IUUC-Csa-023559	Chlorocebus sabaeus	96.51	0.00e+00	1882.00
IUUC-Cho-024862	Choloepus hoffmanni	88.73	0.00e+00	1392.00
IUUC-Cin-025599	Ciona intestinalis	41.93	2.00e-176	612.00
IUUC-Csv-026152	Ciona savignyi	42.55	0.00e+00	760.00
IUUC-Cgl-026551	Colletotrichum gloeosporioides	30.93	2.00e-110	394.00
IUUC-Cne-026907	Cryptococcus neoformans	31.01	2.00e-110	394.00
IUUC-Dre-027747	Danio rerio	65.81	0.00e+00	1343.00
IUUC-Dno-029668	Dasypus novemcinctus	96.41	0.00e+00	1867.00
IUUC-Dor-030404	Dipodomys ordii	90.13	0.00e+00	1742.00
IUUC-Dse-031345	Dothistroma septosporum	33.48	2.00e-120	426.00
IUUC-Dme-031711	Drosophila melanogaster	34.01	2.00e-146	513.00
IUUC-Ete-032308	Echinops telfairi	89.96	0.00e+00	907.00
IUUC-Eca-033637	Equus caballus	97.84	0.00e+00	1907.00
IUUC-Eeu-035151	Erinaceus europaeus	95.55	0.00e+00	1387.00
IUUC-Fca-035585	Felis catus	97.43	0.00e+00	1882.00
IUUC-Fal-037122	Ficedula albicollis	72.10	0.00e+00	1475.00
IUUC-Fox-038030	Fusarium oxysporum	33.71	2.00e-119	424.00
IUUC-Fso-038426	Fusarium solani	33.67	2.00e-124	440.00
IUUC-Gmo-038784	Gadus morhua	66.33	0.00e+00	1302.00
IUUC-Ggr-039973	Gaeumannomyces graminis	33.88	5.00e-120	425.00
IUUC-Gga-040692	Gallus gallus	74.02	0.00e+00	1502.00
IUUC-Gac-041868	Gasterosteus aculeatus	64.62	0.00e+00	1300.00
IUUC-Gma-044274	Glycine max	34.25	7.00e-137	481.00
IUUC-Ggo-045053	Gorilla gorilla	96.71	0.00e+00	1871.00
IUUC-Hsa-046635	Homo sapiens	96.92	0.00e+00	1873.00
IUUC-Hvu-047361	Hordeum vulgare	33.71	2.00e-125	443.00
IUUC-Itr-048868	Ictidomys tridecemlineatus	96.61	0.00e+00	1866.00
IUUC-Kpa-049270	Komagataella pastoris	23.89	3.00e-77	283.00
IUUC-Lch-050188	Latimeria chalumnae	68.65	0.00e+00	1217.00
IUUC-Lpe-051026	Leersia perrieri	34.45	5.00e-129	455.00
IUUC-Loc-051821	Lepisosteus oculatus	67.21	0.00e+00	1335.00
IUUC-Lma-053178	Leptosphaeria maculans	34.15	1.00e-99	357.00
IUUC-Laf-053552	Loxodonta africana	96.71	0.00e+00	1877.00
IUUC-Mcc-054667	Macaca mulatta	96.61	0.00e+00	1867.00
IUUC-Meu-056422	Macropus eugenii	91.52	0.00e+00	855.00
IUUC-Mor-056981	Magnaporthe oryzae	33.40	4.00e-118	419.00
IUUC-Mtr-058703	Medicago truncatula	34.31	5.00e-131	462.00
IUUC-Mla-059088	Melampsora laricipopulina	35.22	5.00e-93	335.00
IUUC-Mga-059798	Meleagris gallopavo	73.72	0.00e+00	1498.00
IUUC-Mvi-060404	Microbotryum violaceum	33.77	3.00e-121	430.00
IUUC-Mmr-061630	Microcebus murinus	97.33	0.00e+00	1885.00
IUUC-Mdo-062354	Monodelphis domestica	93.22	0.00e+00	1832.00
IUUC-Mmu-063199	Mus musculus	95.68	0.00e+00	1869.00
IUUC-Mac-065595	Musa acuminata	35.31	4.00e-112	399.00
IUUC-Mlu-067455	Myotis lucifugus	97.33	0.00e+00	1877.00
IUUC-Nfi-068565	Neosartorya fischeri	32.69	4.00e-114	405.00
IUUC-Ncr-068748	Neurospora crassa	32.67	2.00e-123	437.00
IUUC-Nle-068979	Nomascus leucogenys	96.74	0.00e+00	1678.00
IUUC-Opr-070711	Ochotona princeps	95.58	0.00e+00	1857.00
IUUC-Ont-072603	Oreochromis niloticus	65.62	0.00e+00	1318.00
IUUC-Oan-073136	Ornithorhynchus anatinus	84.52	0.00e+00	815.00
IUUC-Ocu-074496	Oryctolagus cuniculus	97.02	0.00e+00	1877.00
IUUC-Oba-075933	Oryza barthii	33.11	5.00e-109	389.00
IUUC-Obr-076290	Oryza brachyantha	33.68	3.00e-130	459.00
IUUC-Ogu-078728	Oryza glumaepatula	33.11	3.00e-109	389.00
IUUC-Oin-079954	Oryza indica	33.58	1.00e-120	427.00
IUUC-Olo-081033	Oryza longistaminata	31.81	1.00e-103	371.00
IUUC-Ome-081797	Oryza meridionalis	33.00	9.00e-117	414.00
IUUC-Oni-082802	Oryza nivara	33.11	3.00e-109	389.00
IUUC-Opu-083595	Oryza punctata	34.91	9.00e-130	457.00
IUUC-Oru-084199	Oryza rufipogon	33.11	3.00e-109	389.00
IUUC-Osa-085349	Oryza sativa	33.88	2.00e-129	456.00
IUUC-Ola-087482	Oryzias latipes	65.41	0.00e+00	1309.00
IUUC-Olu-087797	Ostreococcus lucimarinus	25.77	1.00e-65	244.00
IUUC-Oga-088817	Otolemur garnettii	96.92	0.00e+00	1898.00
IUUC-Oar-090350	Ovis aries	95.28	0.00e+00	1458.00
IUUC-Ptr-090999	Pan troglodytes	96.61	0.00e+00	1868.00
IUUC-Pan-092704	Papio anubis	96.61	0.00e+00	1867.00
IUUC-Psi-093529	Pelodiscus sinensis	73.61	0.00e+00	1472.00
IUUC-Pma-094400	Petromyzon marinus	56.83	0.00e+00	1092.00
IUUC-Pno-094875	Phaeosphaeria nodorum	31.79	2.00e-117	417.00
IUUC-Ppa-095231	Physcomitrella patens	33.82	2.00e-130	460.00
IUUC-Pfo-096967	Poecilia formosa	65.11	0.00e+00	1310.00
IUUC-Pab-098300	Pongo abelii	96.61	0.00e+00	1866.00
IUUC-Pop-098966	Populus trichocarpa	34.27	3.00e-139	489.00
IUUC-Pca-100643	Procavia capensis	95.41	0.00e+00	1768.00
IUUC-Ppe-101589	Prunus persica	33.85	9.00e-136	478.00
IUUC-Pva-102766	Pteropus vampyrus	96.51	0.00e+00	1830.00
IUUC-Pgr-103330	Puccinia graminis	30.77	2.00e-108	387.00
IUUC-Ptt-103809	Puccinia triticina	31.82	3.00e-90	326.00
IUUC-Pte-104319	Pyrenophora teres	31.88	3.00e-115	409.00
IUUC-Pyt-104798	Pyrenophora triticirepentis	30.70	3.00e-103	369.00
IUUC-Rno-105817	Rattus norvegicus	95.17	0.00e+00	1860.00
IUUC-Sce-106255	Saccharomyces cerevisiae	22.90	2.00e-35	144.00
IUUC-Sha-107479	Sarcophilus harrisii	93.37	0.00e+00	1823.00
IUUC-Sja-107976	Schizosaccharomyces japonicus	25.40	8.00e-69	255.00
IUUC-Spo-108146	Schizosaccharomyces pombe	26.58	1.00e-71	264.00
IUUC-Ssl-108663	Sclerotinia sclerotiorum	33.59	5.00e-109	389.00
IUUC-Smo-109585	Selaginella moellendorffii	33.88	1.00e-119	424.00
IUUC-Sit-110275	Setaria italica	34.39	3.00e-129	456.00
IUUC-Sly-111073	Solanum lycopersicum	34.81	3.00e-135	476.00
IUUC-Stu-112392	Solanum tuberosum	29.31	1.00e-14	72.80
IUUC-Sar-113718	Sorex araneus	93.12	0.00e+00	1793.00
IUUC-Sbi-114080	Sorghum bicolor	34.56	2.00e-133	470.00
IUUC-Sre-115160	Sporisorium reilianum	31.60	2.00e-121	430.00
IUUC-Ssc-115997	Sus scrofa	97.02	0.00e+00	1885.00
IUUC-Tgu-116904	Taeniopygia guttata	72.98	0.00e+00	1329.00
IUUC-Tru-117946	Takifugu rubripes	64.50	0.00e+00	1308.00
IUUC-Tni-119692	Tetraodon nigroviridis	64.90	0.00e+00	1306.00
IUUC-Tca-121455	Theobroma cacao	33.85	1.00e-137	484.00
IUUC-Tre-122128	Trichoderma reesei	32.15	2.00e-120	427.00
IUUC-Tvi-122657	Trichoderma virens	32.66	3.00e-121	429.00
IUUC-Tae-125953	Triticum aestivum	33.88	3.00e-126	446.00
IUUC-Tur-126110	Triticum urartu	30.75	2.00e-93	337.00
IUUC-Tme-127173	Tuber melanosporum	30.25	1.00e-99	357.00
IUUC-Ttr-128420	Tursiops truncatus	96.61	0.00e+00	1872.00
IUUC-Uma-129580	Ustilago maydis	31.44	8.00e-121	428.00
IUUC-Vda-129790	Verticillium dahliae	31.30	2.00e-109	390.00
IUUC-Vvi-131095	Vitis vinifera	33.37	3.00e-132	466.00
IUUC-Xtr-131906	Xenopus tropicalis	68.86	0.00e+00	1364.00
IUUC-Xma-134197	Xiphophorus maculatus	65.51	0.00e+00	1311.00
IUUC-Yli-134617	Yarrowia lipolytica	28.62	4.00e-97	349.00
IUUC-Zma-134979	Zea mays	32.15	1.00e-102	367.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence