iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072287

Ensembl Protein ID

ENSONIP00000016329.1

UniProt Accession

I3K5D4; I3K5D4_ORENI

Genbank Protein ID

ENSONIP00000016329

Protein Name

Guanine nucleotide-binding protein subunit beta-2-like 1

Genbank Nucleotide ID

AERX01036651

Gene Name

gnb2l1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000012984.1	ENSONIT00000016344.1	ENSONIP00000016329.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-44	148.8	146	181
UBD/Beta-Prp	1.40e-54	185.8	12	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrt 32
           gHt++v+c++f    s++++vs+++D+ +kvW+l  
   Q: 146  GHTEWVSCVRFspnsSNPIIVSCGWDKMVKVWNLAN 181
           8***********98544****************865 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf.spdksllatgsrdgtikvwdvttgkl.....lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvh 88
           kgh    +t ++   +  ++++++srd++i+ w++t+  +      rsl+gh+ +v++v +s+dg++ ++g+ D+t+++wdl tg +++
   Q: 12   KGHSG-WVTQIATtPQYPDMILSASRDKSIIMWKLTRDETnygipQRSLKGHSHFVSDVVISSDGQFALSGAWDGTLRLWDLTTGLTTR 99
           55544.555566635566899****************999************************************************* PP
   S: 89   tlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg..nllvsGslDrtvrlWdlktgkllrtl 175
            + gh+++vls++fs+++  +vsGs+d+ti++w++    ++   ++gh+++v+cv+++p++   ++vs++ D++v++W+l++ kl +  
   Q: 100  RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLGVCKYTIQDEGHTEWVSCVRFSPNSsnPIIVSCGWDKMVKVWNLANCKLKTNH 188
           *********************************7765555544899*************998569***************777777666 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlr 252
            g ht++ + ++++++g  ++sg++dg+  lwdl +g+ ++tl    d ++ + fs  + + ++++  +si+iWdl+
   Q: 189  IG-HTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD-SGDVINALCFS-PNRYWLCAATGPSIKIWDLE 262
           76.***********************************999996.45677777777.7889999999********97 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MTEQMTVRGT LKGHSGWVTQ IATTPQYPDM ILSASRDKSI IMWKLTRDET NYGIPQRSLK 60
GHSHFVSDVV ISSDGQFALS GAWDGTLRLW DLTTGLTTRR FVGHTKDVLS VAFSADNRQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGCATTA ACAAAAATGA CAATGTCTGC ATTTTGTGTT TTATTGATTT ATTATTATTA 60
TGATGATGAT GATGATGATG GAAAACGTAC CTTGATACAT TTTTATGATT ATTGTATTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0001525--P:angiogenesis
GO:0060027--P:convergent extension involved in gastrulation
GO:0030178--P:negative regulation of Wnt signaling pathway
GO:2000543--P:positive regulation of gastrulation
GO:0051302--P:regulation of cell division
GO:2000114--P:regulation of establishment of cell polarity
GO:0032880--P:regulation of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000395	Aegilops tauschii	64.44	3.00e-103	367.00
IUUC-Aml-001935	Ailuropoda melanoleuca	94.32	0.00e+00	631.00
IUUC-Atr-002694	Amborella trichopoda	67.73	2.00e-125	442.00
IUUC-Apl-003918	Anas platyrhynchos	94.66	2.00e-161	561.00
IUUC-Aca-004869	Anolis carolinensis	94.32	0.00e+00	631.00
IUUC-Aly-005671	Arabidopsis lyrata	64.81	2.00e-125	442.00
IUUC-Ath-007584	Arabidopsis thaliana	65.74	4.00e-125	441.00
IUUC-Ago-007720	Ashbya gossypii	56.23	1.00e-102	366.00
IUUC-Acl-008156	Aspergillus clavatus	71.79	3.00e-137	481.00
IUUC-Afl-008684	Aspergillus flavus	71.47	3.00e-137	481.00
IUUC-Afu-008867	Aspergillus fumigatus	73.08	2.00e-139	488.00
IUUC-Ani-009221	Aspergillus nidulans	72.44	2.00e-138	485.00
IUUC-Ang-009843	Aspergillus niger	71.47	1.00e-136	479.00
IUUC-Aor-010193	Aspergillus oryzae	71.47	3.00e-137	481.00
IUUC-Ate-010420	Aspergillus terreus	73.14	1.00e-125	442.00
IUUC-Ame-011199	Astyanax mexicanus	95.90	0.00e+00	638.00
IUUC-Bgr-012064	Blumeria graminis	70.51	2.00e-135	475.00
IUUC-Bta-013357	Bos taurus	94.32	0.00e+00	631.00
IUUC-Bci-013862	Botrytis cinerea	71.79	5.00e-138	483.00
IUUC-Bdi-014690	Brachypodium distachyon	62.08	9.00e-114	403.00
IUUC-Bol-016231	Brassica oleracea	65.63	1.00e-126	446.00
IUUC-Bra-016879	Brassica rapa	65.22	4.00e-125	441.00
IUUC-Cel-018335	Caenorhabditis elegans	69.38	5.00e-123	434.00
IUUC-Cja-019914	Callithrix jacchus	94.32	0.00e+00	631.00
IUUC-Cfa-020755	Canis familiaris	94.32	0.00e+00	631.00
IUUC-Cpo-022377	Cavia porcellus	94.32	0.00e+00	633.00
IUUC-Cre-022909	Chlamydomonas reinhardtii	75.24	8.00e-138	483.00
IUUC-Csa-023025	Chlorocebus sabaeus	94.32	0.00e+00	631.00
IUUC-Cin-025647	Ciona intestinalis	78.03	2.00e-147	515.00
IUUC-Csv-026027	Ciona savignyi	77.71	1.00e-145	509.00
IUUC-Cgl-026718	Colletotrichum gloeosporioides	74.91	3.00e-129	454.00
IUUC-Cne-026930	Cryptococcus neoformans	71.47	2.00e-137	481.00
IUUC-Cme-027251	Cyanidioschyzon merolae	62.82	2.00e-120	425.00
IUUC-Dre-028669	Danio rerio	95.90	0.00e+00	635.00
IUUC-Dno-029470	Dasypus novemcinctus	80.13	3.00e-144	504.00
IUUC-Dor-031098	Dipodomys ordii	84.54	5.00e-144	503.00
IUUC-Dse-031255	Dothistroma septosporum	73.40	1.00e-139	489.00
IUUC-Dme-032118	Drosophila melanogaster	77.46	5.00e-148	516.00
IUUC-Ete-033182	Echinops telfairi	79.37	3.00e-102	364.00
IUUC-Eca-033296	Equus caballus	95.33	4.00e-85	306.00
IUUC-Eeu-034771	Erinaceus europaeus	89.27	2.00e-170	591.00
IUUC-Fca-036315	Felis catus	94.32	0.00e+00	631.00
IUUC-Fal-036990	Ficedula albicollis	93.89	8.00e-101	360.00
IUUC-Fox-037702	Fusarium oxysporum	72.12	8.00e-139	486.00
IUUC-Fso-038384	Fusarium solani	72.76	3.00e-139	487.00
IUUC-Gmo-039630	Gadus morhua	95.78	8.00e-179	619.00
IUUC-Ggr-039985	Gaeumannomyces graminis	71.79	2.00e-138	484.00
IUUC-Gga-040540	Gallus gallus	94.32	0.00e+00	631.00
IUUC-Gac-041316	Gasterosteus aculeatus	95.82	4.00e-180	623.00
IUUC-Gma-042872	Glycine max	64.91	5.00e-124	437.00
IUUC-Ggo-045253	Gorilla gorilla	94.32	0.00e+00	631.00
IUUC-Hsa-046809	Homo sapiens	94.32	0.00e+00	631.00
IUUC-Hvu-047683	Hordeum vulgare	62.92	3.00e-115	408.00
IUUC-Itr-048025	Ictidomys tridecemlineatus	94.32	0.00e+00	631.00
IUUC-Kpa-049214	Komagataella pastoris	57.42	2.00e-99	355.00
IUUC-Lch-049634	Latimeria chalumnae	93.38	0.00e+00	625.00
IUUC-Lpe-050763	Leersia perrieri	61.47	8.00e-113	400.00
IUUC-Loc-052163	Lepisosteus oculatus	96.85	0.00e+00	638.00
IUUC-Lma-053113	Leptosphaeria maculans	73.40	2.00e-140	491.00
IUUC-Laf-054422	Loxodonta africana	94.32	0.00e+00	631.00
IUUC-Mcc-055348	Macaca mulatta	94.32	0.00e+00	630.00
IUUC-Meu-056543	Macropus eugenii	94.32	0.00e+00	632.00
IUUC-Mor-057107	Magnaporthe oryzae	72.12	2.00e-139	488.00
IUUC-Mpo-057487	Magnaporthe poae	72.12	6.00e-139	486.00
IUUC-Mtr-058808	Medicago truncatula	65.22	1.00e-124	439.00
IUUC-Mla-058909	Melampsora laricipopulina	73.16	3.00e-140	491.00
IUUC-Mga-059387	Meleagris gallopavo	94.32	0.00e+00	631.00
IUUC-Mvi-060392	Microbotryum violaceum	69.87	2.00e-135	475.00
IUUC-Mmr-061141	Microcebus murinus	85.12	1.00e-134	472.00
IUUC-Mdo-062932	Monodelphis domestica	94.32	0.00e+00	631.00
IUUC-Mmu-064132	Mus musculus	94.32	0.00e+00	631.00
IUUC-Mac-064447	Musa acuminata	61.11	2.00e-109	388.00
IUUC-Mpu-066721	Mustela putorius furo	93.38	6.00e-179	619.00
IUUC-Mlu-068221	Myotis lucifugus	93.69	8.00e-171	592.00
IUUC-Nfi-068344	Neosartorya fischeri	73.08	2.00e-139	488.00
IUUC-Ncr-068722	Neurospora crassa	71.47	2.00e-137	481.00
IUUC-Nle-069865	Nomascus leucogenys	94.32	0.00e+00	631.00
IUUC-Opr-071100	Ochotona princeps	79.50	1.00e-145	509.00
IUUC-Oan-072788	Ornithorhynchus anatinus	94.32	0.00e+00	631.00
IUUC-Ocu-073844	Oryctolagus cuniculus	91.80	1.00e-175	608.00
IUUC-Oba-075981	Oryza barthii	59.32	2.00e-102	365.00
IUUC-Obr-076099	Oryza brachyantha	60.86	2.00e-112	399.00
IUUC-Ogl-077804	Oryza glaberrima	62.08	2.00e-114	405.00
IUUC-Ogu-078035	Oryza glumaepatula	62.77	3.00e-114	404.00
IUUC-Oin-079327	Oryza indica	62.77	3.00e-114	404.00
IUUC-Olo-081084	Oryza longistaminata	62.77	3.00e-114	404.00
IUUC-Ome-081366	Oryza meridionalis	62.39	7.00e-115	406.00
IUUC-Oni-082682	Oryza nivara	62.39	7.00e-115	406.00
IUUC-Opu-084010	Oryza punctata	62.08	6.00e-115	407.00
IUUC-Oru-084358	Oryza rufipogon	62.39	7.00e-115	406.00
IUUC-Osa-085296	Oryza sativa	62.39	7.00e-115	406.00
IUUC-Ola-086400	Oryzias latipes	99.68	0.00e+00	652.00
IUUC-Olu-087817	Ostreococcus lucimarinus	74.84	4.00e-141	493.00
IUUC-Oga-088811	Otolemur garnettii	94.32	0.00e+00	631.00
IUUC-Oar-089962	Ovis aries	94.32	0.00e+00	631.00
IUUC-Ptr-091340	Pan troglodytes	94.32	0.00e+00	631.00
IUUC-Pan-091946	Papio anubis	94.32	0.00e+00	631.00
IUUC-Pma-094535	Petromyzon marinus	93.38	9.00e-180	622.00
IUUC-Pno-095100	Phaeosphaeria nodorum	75.94	4.00e-98	350.00
IUUC-Ppa-095752	Physcomitrella patens	75.72	1.00e-140	492.00
IUUC-Pfo-097311	Poecilia formosa	98.42	0.00e+00	647.00
IUUC-Pab-097863	Pongo abelii	94.32	0.00e+00	632.00
IUUC-Pop-099345	Populus trichocarpa	68.11	8.00e-129	453.00
IUUC-Pca-100594	Procavia capensis	93.69	0.00e+00	627.00
IUUC-Ppe-101743	Prunus persica	65.12	1.00e-123	436.00
IUUC-Pva-102746	Pteropus vampyrus	79.50	5.00e-145	507.00
IUUC-Pgr-103375	Puccinia graminis	54.95	5.00e-96	343.00
IUUC-Ptt-103839	Puccinia triticina	72.84	3.00e-138	484.00
IUUC-Pte-104026	Pyrenophora teres	73.40	2.00e-140	491.00
IUUC-Pyt-104584	Pyrenophora triticirepentis	73.40	2.00e-140	491.00
IUUC-Rno-104964	Rattus norvegicus	94.32	0.00e+00	631.00
IUUC-Sce-106224	Saccharomyces cerevisiae	54.46	1.00e-97	350.00
IUUC-Sha-107409	Sarcophilus harrisii	94.32	0.00e+00	631.00
IUUC-Sja-107971	Schizosaccharomyces japonicus	65.81	7.00e-127	446.00
IUUC-Spo-108297	Schizosaccharomyces pombe	64.86	6.00e-124	436.00
IUUC-Ssl-108479	Sclerotinia sclerotiorum	71.79	5.00e-138	483.00
IUUC-Smo-109017	Selaginella moellendorffii	70.25	2.00e-129	454.00
IUUC-Sit-110060	Setaria italica	63.69	3.00e-117	414.00
IUUC-Sly-111839	Solanum lycopersicum	66.56	3.00e-126	444.00
IUUC-Stu-112180	Solanum tuberosum	66.25	8.00e-126	443.00
IUUC-Sar-113173	Sorex araneus	94.32	0.00e+00	631.00
IUUC-Sbi-114681	Sorghum bicolor	63.38	4.00e-116	410.00
IUUC-Sre-115107	Sporisorium reilianum	69.87	8.00e-138	483.00
IUUC-Ssc-116218	Sus scrofa	90.22	2.00e-174	604.00
IUUC-Tru-118202	Takifugu rubripes	95.58	0.00e+00	632.00
IUUC-Tni-120260	Tetraodon nigroviridis	94.64	1.00e-180	625.00
IUUC-Tca-120951	Theobroma cacao	66.46	1.00e-126	446.00
IUUC-Tre-121961	Trichoderma reesei	73.40	2.00e-140	491.00
IUUC-Tvi-122447	Trichoderma virens	72.76	5.00e-139	487.00
IUUC-Tae-123560	Triticum aestivum	62.31	2.00e-114	405.00
IUUC-Tur-126335	Triticum urartu	67.78	8.00e-105	373.00
IUUC-Tme-127105	Tuber melanosporum	69.90	7.00e-128	449.00
IUUC-Tbe-128021	Tupaia belangeri	76.73	2.00e-84	304.00
IUUC-Ttr-128637	Tursiops truncatus	82.65	2.00e-155	541.00
IUUC-Uma-129634	Ustilago maydis	70.83	1.00e-138	486.00
IUUC-Vda-129923	Verticillium dahliae	72.12	1.00e-138	485.00
IUUC-Vpa-130410	Vicugna pacos	73.36	1.00e-107	382.00
IUUC-Vvi-131115	Vitis vinifera	65.12	1.00e-125	442.00
IUUC-Xtr-132105	Xenopus tropicalis	94.32	0.00e+00	632.00
IUUC-Xma-133875	Xiphophorus maculatus	98.42	0.00e+00	647.00
IUUC-Yli-134624	Yarrowia lipolytica	61.39	6.00e-120	423.00
IUUC-Zma-134711	Zea mays	62.77	5.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence