iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ztr-136060

Ensembl Protein ID

Mycgr3P69971

UniProt Accession

F9X6B3; F9X6B3_ZYMTI

Genbank Protein ID

EGP88864.1

Protein Name

Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog

Genbank Nucleotide ID

CM001198

Gene Name

PAC1; LIS1; MYCGRDRAFT_69971

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Mycgr3G69971	Mycgr3T69971	Mycgr3P69971

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-51	168.6	202	249
UBD/Beta-Prp	3.30e-62	209.5	115	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..........sdtllvsGsdDgtikvWDlrtgvllks 38
           gH  sv++++f          s++ll+s+s+D+ti++WD++tg +l++
   Q: 202  GHDHSVSSVRFipsgaagaplSGNLLASASRDKTIRIWDVTTGYCLRT 249
           8*******************877********************99875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfs.pdgk.ilvtgseDrtikvwdls.tgkcvhtlkghedsvlsl 100
           + h ++itcv+f+p  s la+gs+d tik+wd++ g l r+l++h+++v +v+f  p+g+ +l+++s+D tik+wd+   +k ++tl gh++sv s+
   Q: 115  S-HRQPITCVAFHPLFSSLASGSEDCTIKIWDYELGELERTLKSHTKAVLDVDFGgPRGNtLLASCSSDLTIKLWDPAeEYKNIRTLPGHDHSVSSV 210
           4.566*************************************************7345558**************65449***************** PP
   S: 101  sfsp........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgghtdsvysl 186
           +f p        sg+ l+s+s+d+tir+wd+ tg+cl+ tl+gh+++v++++   dg+ l s s D+t r+Wdl    ++   +t+ g h++ v++ 
   Q: 211  RFIPsgaagaplSGNLLASASRDKTIRIWDVTTGYCLR-TLRGHNDWVRSLSPTFDGRWLLSTSSDQTSRMWDLsqpDSNAQKQTFMG-HEHVVECC 305
           ***99999999999************************.***********************************88888888999*99.******** PP
   S: 187  sfdsngke 194
           +f +   +
   Q: 306  AFAPPAAY 313
           99886644 PP

Organism

Zymoseptoria tritici

Functional Description
(View)

Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.

Protein Sequence
(Fasta)

MSVLLTSRQA EELHKSLIAY LLSTGHADSA QVLRDNLNLP ESDFDAATAK KYEGLLEKKW 60
TSVVRLQKKI MDLEARSQQL QQELDSATPS SLAARKNHDP QTWLPRAPAR HTLMSHRQPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAAAGACA AGTCTACGCA CTATCGCAAC CTCGAATTCA AGCTTCGCGG CTCTCATACA 60
ACGATCAACA ACCGTCCAGT CCCAACCTAC ACACTCTCGA GTCCTCATCA GCTTTGCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0000132--P:establishment of mitotic spindle orientation
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

KEGG

ztr:MYCGRDRAFT_69971

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001589	Ailuropoda melanoleuca	44.72	6.00e-101	358.00
IUUC-Apl-004024	Anas platyrhynchos	44.50	5.00e-104	369.00
IUUC-Aca-004564	Anolis carolinensis	44.50	8.00e-103	365.00
IUUC-Ago-007862	Ashbya gossypii	28.89	4.00e-41	160.00
IUUC-Acl-008360	Aspergillus clavatus	67.52	7.00e-176	608.00
IUUC-Afl-008502	Aspergillus flavus	57.68	4.00e-157	545.00
IUUC-Afu-008848	Aspergillus fumigatus	68.15	0.00e+00	644.00
IUUC-Ani-009173	Aspergillus nidulans	57.45	7.00e-154	535.00
IUUC-Ang-009873	Aspergillus niger	54.45	4.00e-148	515.00
IUUC-Aor-009973	Aspergillus oryzae	55.70	2.00e-153	533.00
IUUC-Ate-010523	Aspergillus terreus	57.05	3.00e-153	532.00
IUUC-Ame-011154	Astyanax mexicanus	44.50	1.00e-103	367.00
IUUC-Bgr-011972	Blumeria graminis	64.81	0.00e+00	627.00
IUUC-Bta-013106	Bos taurus	44.74	2.00e-104	370.00
IUUC-Bci-013615	Botrytis cinerea	69.36	0.00e+00	647.00
IUUC-Cel-018459	Caenorhabditis elegans	43.52	7.00e-95	338.00
IUUC-Cja-018755	Callithrix jacchus	43.52	1.00e-101	361.00
IUUC-Cfa-020749	Canis familiaris	44.74	2.00e-104	370.00
IUUC-Cpo-022371	Cavia porcellus	44.74	2.00e-104	370.00
IUUC-Csa-023524	Chlorocebus sabaeus	44.87	3.00e-86	310.00
IUUC-Cho-024764	Choloepus hoffmanni	42.94	1.00e-86	311.00
IUUC-Cin-025753	Ciona intestinalis	44.17	1.00e-94	338.00
IUUC-Csv-025817	Ciona savignyi	43.28	7.00e-97	345.00
IUUC-Cgl-026529	Colletotrichum gloeosporioides	69.40	0.00e+00	629.00
IUUC-Cne-027087	Cryptococcus neoformans	52.54	3.00e-112	396.00
IUUC-Dre-027554	Danio rerio	44.01	2.00e-102	364.00
IUUC-Dno-029050	Dasypus novemcinctus	44.50	4.00e-104	369.00
IUUC-Dor-030222	Dipodomys ordii	41.91	4.00e-96	343.00
IUUC-Dse-031164	Dothistroma septosporum	89.83	0.00e+00	866.00
IUUC-Dme-031745	Drosophila melanogaster	45.01	1.00e-93	334.00
IUUC-Ete-032508	Echinops telfairi	45.35	2.00e-67	247.00
IUUC-Eca-034288	Equus caballus	44.22	6.00e-100	355.00
IUUC-Eeu-034984	Erinaceus europaeus	41.67	4.00e-95	339.00
IUUC-Fca-036498	Felis catus	44.74	2.00e-104	370.00
IUUC-Fal-036920	Ficedula albicollis	44.50	5.00e-104	369.00
IUUC-Fox-037996	Fusarium oxysporum	67.96	0.00e+00	662.00
IUUC-Fso-038160	Fusarium solani	65.38	1.00e-180	624.00
IUUC-Gmo-038983	Gadus morhua	44.53	2.00e-103	367.00
IUUC-Ggr-040051	Gaeumannomyces graminis	61.97	4.00e-172	595.00
IUUC-Gga-040623	Gallus gallus	44.50	5.00e-104	369.00
IUUC-Gac-041613	Gasterosteus aculeatus	44.50	4.00e-103	365.00
IUUC-Ggo-045410	Gorilla gorilla	42.35	8.00e-85	305.00
IUUC-Hsa-046358	Homo sapiens	44.74	3.00e-104	369.00
IUUC-Itr-047890	Ictidomys tridecemlineatus	44.74	2.00e-104	370.00
IUUC-Kpa-049351	Komagataella pastoris	30.25	1.00e-45	175.00
IUUC-Lch-049936	Latimeria chalumnae	44.01	1.00e-103	367.00
IUUC-Loc-052476	Lepisosteus oculatus	44.22	1.00e-100	357.00
IUUC-Lma-053170	Leptosphaeria maculans	69.89	0.00e+00	637.00
IUUC-Laf-053713	Loxodonta africana	44.89	5.00e-102	362.00
IUUC-Mcc-054628	Macaca mulatta	44.50	5.00e-104	369.00
IUUC-Meu-055927	Macropus eugenii	37.17	8.00e-49	185.00
IUUC-Mor-056962	Magnaporthe oryzae	63.20	1.00e-177	614.00
IUUC-Mpo-057583	Magnaporthe poae	62.02	7.00e-167	578.00
IUUC-Mla-058819	Melampsora laricipopulina	46.91	6.00e-114	402.00
IUUC-Mga-059945	Meleagris gallopavo	44.25	1.00e-103	367.00
IUUC-Mvi-060403	Microbotryum violaceum	50.54	1.00e-126	444.00
IUUC-Mmr-061289	Microcebus murinus	44.33	5.00e-101	359.00
IUUC-Mdo-061912	Monodelphis domestica	44.50	8.00e-104	368.00
IUUC-Mmu-063253	Mus musculus	44.74	2.00e-104	370.00
IUUC-Mpu-066638	Mustela putorius furo	44.74	2.00e-104	370.00
IUUC-Mlu-067267	Myotis lucifugus	43.73	2.00e-101	360.00
IUUC-Nfi-068571	Neosartorya fischeri	62.63	1.00e-170	590.00
IUUC-Ncr-068895	Neurospora crassa	68.53	0.00e+00	637.00
IUUC-Nle-069087	Nomascus leucogenys	43.54	2.00e-84	303.00
IUUC-Opr-070579	Ochotona princeps	44.50	4.00e-104	369.00
IUUC-Ont-072432	Oreochromis niloticus	44.25	3.00e-103	366.00
IUUC-Oan-073072	Ornithorhynchus anatinus	44.74	2.00e-104	370.00
IUUC-Ocu-074180	Oryctolagus cuniculus	44.50	4.00e-104	369.00
IUUC-Ola-086815	Oryzias latipes	44.50	6.00e-104	369.00
IUUC-Oga-088219	Otolemur garnettii	44.12	9.00e-102	361.00
IUUC-Oar-090394	Ovis aries	44.74	2.00e-104	370.00
IUUC-Ptr-091517	Pan troglodytes	44.74	2.00e-104	370.00
IUUC-Pan-092421	Papio anubis	44.50	5.00e-104	369.00
IUUC-Psi-093370	Pelodiscus sinensis	44.50	8.00e-104	368.00
IUUC-Pma-094319	Petromyzon marinus	44.31	3.00e-85	306.00
IUUC-Pno-094815	Phaeosphaeria nodorum	68.52	0.00e+00	641.00
IUUC-Pfo-097089	Poecilia formosa	44.50	1.00e-103	367.00
IUUC-Pab-098421	Pongo abelii	44.74	2.00e-104	370.00
IUUC-Pca-100120	Procavia capensis	36.86	8.00e-59	219.00
IUUC-Pva-102960	Pteropus vampyrus	44.25	9.00e-103	365.00
IUUC-Pgr-103538	Puccinia graminis	48.19	1.00e-116	411.00
IUUC-Ptt-103990	Puccinia triticina	42.80	1.00e-42	166.00
IUUC-Pte-104261	Pyrenophora teres	69.53	0.00e+00	649.00
IUUC-Pyt-104780	Pyrenophora triticirepentis	70.39	0.00e+00	650.00
IUUC-Rno-105123	Rattus norvegicus	44.74	2.00e-104	370.00
IUUC-Sce-106208	Saccharomyces cerevisiae	29.38	1.00e-37	149.00
IUUC-Sha-107010	Sarcophilus harrisii	44.74	5.00e-104	369.00
IUUC-Sja-107899	Schizosaccharomyces japonicus	35.63	9.00e-66	242.00
IUUC-Ssl-108571	Sclerotinia sclerotiorum	69.54	0.00e+00	628.00
IUUC-Sar-113309	Sorex araneus	43.97	4.00e-98	349.00
IUUC-Sre-115003	Sporisorium reilianum	48.70	5.00e-123	432.00
IUUC-Ssc-116148	Sus scrofa	44.74	2.00e-104	370.00
IUUC-Tgu-117299	Taeniopygia guttata	44.25	3.00e-103	366.00
IUUC-Tru-118179	Takifugu rubripes	44.01	8.00e-103	365.00
IUUC-Tsy-119493	Tarsius syrichta	44.50	3.00e-103	366.00
IUUC-Tni-120355	Tetraodon nigroviridis	44.01	4.00e-101	359.00
IUUC-Tre-121977	Trichoderma reesei	60.25	6.00e-162	561.00
IUUC-Tvi-122661	Trichoderma virens	60.72	4.00e-162	562.00
IUUC-Tme-127031	Tuber melanosporum	62.17	9.00e-167	577.00
IUUC-Tbe-127492	Tupaia belangeri	38.66	1.00e-46	178.00
IUUC-Ttr-128929	Tursiops truncatus	44.50	8.00e-104	368.00
IUUC-Uma-129347	Ustilago maydis	48.28	7.00e-119	418.00
IUUC-Vda-129837	Verticillium dahliae	67.81	4.00e-176	608.00
IUUC-Vpa-130532	Vicugna pacos	38.73	5.00e-85	305.00
IUUC-Xtr-131985	Xenopus tropicalis	44.74	2.00e-104	370.00
IUUC-Xma-133314	Xiphophorus maculatus	44.50	1.00e-103	368.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence