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Tag Content
UUCD2 ID IUUC-Ssc-116066
UUCD1 version UUC-SuS-00557
Ensembl Protein ID ENSSSCP00000017075.2
UniProt Accession F1SHE8; F1SHE8_PIG
Genbank Protein ID ENSSSCP00000017075
Protein Name Ribosome biogenesis protein WDR12; WD repeat-containing protein 12
Genbank Nucleotide ID CU469263
Gene Name WDR12
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSSCG00000016116.2 ENSSSCT00000017547.2 ENSSSCP00000017075.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.40e-42 142.1 341 376
UBD/Beta-Prp 6.70e-46 157.1 246 412
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlrtgv 34
           Ht++vt++++  +    l+sGs D+ +k+WD+r+++
   Q: 341  HTGWVTSVKWspTHeQQLISGSLDNIVKLWDTRSCK 376
           **********9533678**************99876 PP
   

   UBD/Beta-Prp
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..ktg 169
           t+++++tl+gh++ + s+ +s   + + s+s+d ti vwd+e+g+  + tl+g++ v nc++++p ++ l+sGs+Dr +rlWd   k g
   Q: 246  TRTPIVTLSGHKEAISSVLWSD-AEEICSASWDHTIGVWDVESGSLKS-TLTGNK-VFNCISYSPLCKRLASGSTDRHIRLWDPrtKDG 331
           67899****************9.99**********************9.***987.99**************************54456 PP
   S: 170  kllrtl.tgghtdsvyslsfdsng.kelvsgsldgtvklwdlq.tgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           +l+    t+ ht+ v+s++++++  ++l+sgsld+ vklwd +  +  ++ l +h+d v+sv+ + n+ +l+sg++D+ ++ +
   Q: 332  SLVSLSlTS-HTGWVTSVKWSPTHeQQLISGSLDNIVKLWDTRsCKAPLYDLAAHEDKVLSVDWT-NTGLLLSGGADNKLYSY 412
           666644366.************9889*****************54566****************9.***********998765 PP
   
Organism Sus scrofa
Functional Description
(View)

Functional Description


     Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
 Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Protein Sequence
(Fasta)
MAQLQTRFFT DNKKYAVDDV PFSIPAASEI ADLSNIINKL LEAKNEFHKH VEFDFLIKGQ 60
FLRMPLFKHM ELENISSEEV VELEYVEKYT APQPEQCMFH DDWISAIEGA EEWILTGSYD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ssc-116066|E3,WD_repeat;UBD,Beta-Prp|Sus scrofa
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TCCTAAATCT AGGAATAGGT AGTCGATGTT TGTGGGCTGG GCCTTGTGGA AGGGGAGCCT 60
CGTGGTGCTT TCTGGCTAGG CAGGCCGGAG GAAGGAAAGC GGAAGCCCGG AGTTGGACTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ssc-116066|E3,WD_repeat;UBD,Beta-Prp|Sus scrofa
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR028599--WDR12/Ytm1
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0008283--P:cell proliferation
GO:0000460--P:maturation of 5.8S rRNA
GO:0000466--P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470--P:maturation of LSU-rRNA
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0007219--P:Notch signaling pathway
KEGG ssc:100512929
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000532 Aegilops tauschii 32.78 2.00e-56 213.00
IUUC-Aml-001997 Ailuropoda melanoleuca 97.07 0.00e+00 749.00
IUUC-Atr-002544 Amborella trichopoda 33.33 7.00e-56 211.00
IUUC-Apl-003981 Anas platyrhynchos 86.44 0.00e+00 640.00
IUUC-Aca-004370 Anolis carolinensis 84.47 0.00e+00 700.00
IUUC-Aly-006455 Arabidopsis lyrata 34.48 4.00e-58 218.00
IUUC-Ath-006669 Arabidopsis thaliana 33.66 2.00e-53 203.00
IUUC-Ago-007864 Ashbya gossypii 30.39 5.00e-37 148.00
IUUC-Acl-008177 Aspergillus clavatus 27.74 4.00e-34 139.00
IUUC-Afl-008617 Aspergillus flavus 28.46 9.00e-34 137.00
IUUC-Afu-008752 Aspergillus fumigatus 27.80 2.00e-30 126.00
IUUC-Ani-009136 Aspergillus nidulans 29.49 2.00e-33 136.00
IUUC-Ang-009701 Aspergillus niger 27.44 4.00e-31 129.00
IUUC-Aor-009884 Aspergillus oryzae 28.72 2.00e-33 136.00
IUUC-Ame-011432 Astyanax mexicanus 75.65 0.00e+00 647.00
IUUC-Bgr-012218 Blumeria graminis 27.88 9.00e-31 127.00
IUUC-Bta-012829 Bos taurus 98.11 0.00e+00 783.00
IUUC-Bci-013953 Botrytis cinerea 29.79 2.00e-34 139.00
IUUC-Bdi-014351 Brachypodium distachyon 35.55 2.00e-55 209.00
IUUC-Bol-016514 Brassica oleracea 33.57 5.00e-53 201.00
IUUC-Bra-016988 Brassica rapa 33.57 7.00e-53 201.00
IUUC-Cel-018569 Caenorhabditis elegans 32.28 4.00e-49 188.00
IUUC-Cja-019468 Callithrix jacchus 95.51 0.00e+00 749.00
IUUC-Cfa-020471 Canis familiaris 95.98 0.00e+00 745.00
IUUC-Cpo-022260 Cavia porcellus 96.22 0.00e+00 755.00
IUUC-Cre-022614 Chlamydomonas reinhardtii 30.20 2.00e-37 149.00
IUUC-Csa-023989 Chlorocebus sabaeus 95.98 0.00e+00 754.00
IUUC-Cho-024426 Choloepus hoffmanni 91.75 3.00e-157 547.00
IUUC-Cin-025789 Ciona intestinalis 42.93 3.00e-95 342.00
IUUC-Cne-027063 Cryptococcus neoformans 24.64 5.00e-21 95.10
IUUC-Dre-027907 Danio rerio 76.83 0.00e+00 663.00
IUUC-Dno-029225 Dasypus novemcinctus 94.80 0.00e+00 761.00
IUUC-Dor-031082 Dipodomys ordii 78.96 2.00e-169 587.00
IUUC-Dse-031308 Dothistroma septosporum 27.27 6.00e-34 138.00
IUUC-Dme-032189 Drosophila melanogaster 41.75 4.00e-93 334.00
IUUC-Ete-032247 Echinops telfairi 88.42 0.00e+00 705.00
IUUC-Eca-034285 Equus caballus 96.93 0.00e+00 773.00
IUUC-Eeu-035322 Erinaceus europaeus 85.68 0.00e+00 643.00
IUUC-Fca-036114 Felis catus 96.45 0.00e+00 771.00
IUUC-Fal-036891 Ficedula albicollis 85.88 1.00e-172 598.00
IUUC-Fox-037965 Fusarium oxysporum 25.37 1.00e-33 137.00
IUUC-Fso-038244 Fusarium solani 26.64 3.00e-33 135.00
IUUC-Gmo-039040 Gadus morhua 75.18 0.00e+00 666.00
IUUC-Ggr-040093 Gaeumannomyces graminis 24.77 8.00e-11 61.60
IUUC-Gga-040610 Gallus gallus 83.45 0.00e+00 705.00
IUUC-Gac-042117 Gasterosteus aculeatus 75.41 0.00e+00 650.00
IUUC-Gma-043146 Glycine max 36.45 5.00e-65 241.00
IUUC-Ggo-045179 Gorilla gorilla 95.51 0.00e+00 746.00
IUUC-Hsa-046114 Homo sapiens 96.22 0.00e+00 752.00
IUUC-Hvu-047331 Hordeum vulgare 33.33 5.00e-52 197.00
IUUC-Itr-048275 Ictidomys tridecemlineatus 96.45 0.00e+00 772.00
IUUC-Kpa-049304 Komagataella pastoris 28.89 6.00e-40 157.00
IUUC-Lch-050655 Latimeria chalumnae 77.31 2.00e-143 501.00
IUUC-Lpe-051675 Leersia perrieri 34.61 2.00e-57 216.00
IUUC-Loc-052868 Lepisosteus oculatus 81.09 0.00e+00 668.00
IUUC-Lma-053258 Leptosphaeria maculans 26.85 2.00e-31 131.00
IUUC-Laf-053993 Loxodonta africana 94.80 0.00e+00 767.00
IUUC-Mcc-055128 Macaca mulatta 78.72 4.00e-171 593.00
IUUC-Meu-056501 Macropus eugenii 79.09 4.00e-162 563.00
IUUC-Mor-057114 Magnaporthe oryzae 26.00 2.00e-25 110.00
IUUC-Mtr-058367 Medicago truncatula 35.73 1.00e-58 220.00
IUUC-Mla-059107 Melampsora laricipopulina 27.65 4.00e-30 125.00
IUUC-Mga-059745 Meleagris gallopavo 81.41 0.00e+00 679.00
IUUC-Mvi-060362 Microbotryum violaceum 29.10 1.00e-32 134.00
IUUC-Mdo-062257 Monodelphis domestica 86.63 0.00e+00 720.00
IUUC-Mmu-063546 Mus musculus 93.62 0.00e+00 756.00
IUUC-Mac-065540 Musa acuminata 33.49 2.00e-53 202.00
IUUC-Mpu-066284 Mustela putorius furo 97.87 0.00e+00 781.00
IUUC-Mlu-067241 Myotis lucifugus 95.74 0.00e+00 768.00
IUUC-Nfi-068260 Neosartorya fischeri 27.07 3.00e-32 132.00
IUUC-Ncr-068719 Neurospora crassa 26.74 3.00e-26 112.00
IUUC-Nle-068981 Nomascus leucogenys 95.98 0.00e+00 731.00
IUUC-Opr-071218 Ochotona princeps 87.19 0.00e+00 665.00
IUUC-Ont-071646 Oreochromis niloticus 77.11 0.00e+00 669.00
IUUC-Oan-073453 Ornithorhynchus anatinus 89.83 0.00e+00 756.00
IUUC-Ocu-074008 Oryctolagus cuniculus 96.45 0.00e+00 773.00
IUUC-Oba-075712 Oryza barthii 30.53 4.00e-41 162.00
IUUC-Obr-076721 Oryza brachyantha 34.29 1.00e-57 216.00
IUUC-Ogl-077229 Oryza glaberrima 34.37 7.00e-57 214.00
IUUC-Ogu-078977 Oryza glumaepatula 30.53 2.00e-41 162.00
IUUC-Oin-079683 Oryza indica 34.37 3.00e-57 215.00
IUUC-Olo-080291 Oryza longistaminata 30.30 7.00e-28 117.00
IUUC-Ome-081834 Oryza meridionalis 34.61 7.00e-58 218.00
IUUC-Oni-082507 Oryza nivara 33.25 5.00e-53 201.00
IUUC-Opu-083396 Oryza punctata 34.37 1.00e-57 217.00
IUUC-Oru-085220 Oryza rufipogon 33.81 1.00e-52 200.00
IUUC-Osa-085767 Oryza sativa 34.37 3.00e-57 215.00
IUUC-Ola-087420 Oryzias latipes 77.30 0.00e+00 666.00
IUUC-Olu-087740 Ostreococcus lucimarinus 27.40 6.00e-35 141.00
IUUC-Oga-088264 Otolemur garnettii 95.04 0.00e+00 746.00
IUUC-Oar-089335 Ovis aries 97.64 0.00e+00 779.00
IUUC-Ptr-091320 Pan troglodytes 96.22 0.00e+00 752.00
IUUC-Pan-092833 Papio anubis 95.51 0.00e+00 749.00
IUUC-Psi-093504 Pelodiscus sinensis 87.47 0.00e+00 731.00
IUUC-Pma-094189 Petromyzon marinus 68.63 4.00e-170 590.00
IUUC-Pno-094929 Phaeosphaeria nodorum 26.42 7.00e-32 131.00
IUUC-Ppa-095429 Physcomitrella patens 34.91 1.00e-63 236.00
IUUC-Pfo-096337 Poecilia formosa 74.70 0.00e+00 666.00
IUUC-Pab-097571 Pongo abelii 95.74 0.00e+00 751.00
IUUC-Pop-099977 Populus trichocarpa 35.10 2.00e-62 233.00
IUUC-Pca-100394 Procavia capensis 89.00 0.00e+00 665.00
IUUC-Ppe-101848 Prunus persica 34.86 4.00e-59 221.00
IUUC-Pva-102921 Pteropus vampyrus 95.95 2.00e-115 408.00
IUUC-Pgr-103637 Puccinia graminis 28.39 2.00e-33 137.00
IUUC-Ptt-103781 Puccinia triticina 28.39 2.00e-33 136.00
IUUC-Pte-104135 Pyrenophora teres 26.07 2.00e-32 134.00
IUUC-Pyt-104609 Pyrenophora triticirepentis 25.93 2.00e-31 129.00
IUUC-Rno-105114 Rattus norvegicus 92.67 0.00e+00 751.00
IUUC-Sce-106401 Saccharomyces cerevisiae 29.52 1.00e-37 150.00
IUUC-Sha-107122 Sarcophilus harrisii 86.86 0.00e+00 692.00
IUUC-Sja-107766 Schizosaccharomyces japonicus 31.78 3.00e-47 182.00
IUUC-Spo-108134 Schizosaccharomyces pombe 28.67 1.00e-37 150.00
IUUC-Ssl-108398 Sclerotinia sclerotiorum 29.27 2.00e-35 143.00
IUUC-Smo-108720 Selaginella moellendorffii 32.86 7.00e-56 211.00
IUUC-Sit-110311 Setaria italica 35.55 5.00e-56 211.00
IUUC-Sly-111023 Solanum lycopersicum 32.08 9.00e-53 200.00
IUUC-Stu-112778 Solanum tuberosum 35.08 2.00e-59 222.00
IUUC-Sar-113596 Sorex araneus 79.20 3.00e-175 607.00
IUUC-Sbi-114193 Sorghum bicolor 34.96 5.00e-57 214.00
IUUC-Sre-115002 Sporisorium reilianum 24.14 5.00e-11 62.40
IUUC-Tgu-117048 Taeniopygia guttata 84.57 0.00e+00 634.00
IUUC-Tsy-119573 Tarsius syrichta 61.96 2.00e-129 454.00
IUUC-Tni-119820 Tetraodon nigroviridis 75.77 0.00e+00 666.00
IUUC-Tca-121605 Theobroma cacao 35.82 1.00e-60 226.00
IUUC-Tre-121947 Trichoderma reesei 26.50 1.00e-33 137.00
IUUC-Tvi-122481 Trichoderma virens 26.50 9.00e-35 140.00
IUUC-Tae-125861 Triticum aestivum 33.02 1.00e-56 213.00
IUUC-Tur-126586 Triticum urartu 33.59 4.00e-54 204.00
IUUC-Tme-126900 Tuber melanosporum 32.15 2.00e-48 186.00
IUUC-Tbe-127736 Tupaia belangeri 72.86 1.00e-151 529.00
IUUC-Ttr-129041 Tursiops truncatus 85.82 0.00e+00 671.00
IUUC-Vpa-130260 Vicugna pacos 98.11 0.00e+00 781.00
IUUC-Vvi-131009 Vitis vinifera 35.00 2.00e-59 223.00
IUUC-Xtr-132083 Xenopus tropicalis 80.38 0.00e+00 668.00
IUUC-Xma-133094 Xiphophorus maculatus 74.00 0.00e+00 660.00
IUUC-Yli-134531 Yarrowia lipolytica 23.05 7.00e-19 88.20
IUUC-Zma-135509 Zea mays 33.57 9.00e-58 217.00
Created Date 25-Jun-2017

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