iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072852

UUCD1 version

UUC-OrA-00456

Ensembl Protein ID

ENSOANP00000010793.2

UniProt Accession

F7C3T3; F7C3T3_ORNAN

Protein Name

Uncharacterized protein

Gene Name

PIK3R4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006762.3	ENSOANT00000010795.3	ENSOANP00000010793.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-17	62.4	996	1025

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v+ ++  ++  l++++s+Dgt+k+W+
   Q: 996  HKSAVNRIRVsDEhSLFATCSNDGTVKIWN 1025
           9999999999544788*************9 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MGNQLAGIAP SQILSVDSYF SDIHDFEYDK SLGSTRFFKV ARAKHREGFV VVKVFAIQDP 60
TLPLTSYKQE LEELKIRLHS AQNCLPFQKA TMTEKAAMLF RQYVRDNLYD RISTRPFLNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCCGGGGA GTCGGCCTCC TACCGAGGAG GAGGAGGAGG AGCTTGAGGA GTCCGAGGAG 60
GCCCGGGAAG GCGGCGCAGC CCAGCAGCCG GCCTCCGACT ACCAGGTCAG CCGCGGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR021133--HEAT_type_2
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50077--HEAT_REPEAT
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00069--Pkinase
PF00400--WD40

SMART

SM00220--S_TKc
SM00320--WD40

Gene Ontology

GO:0005930--C:axoneme
GO:0005770--C:late endosome
GO:0015630--C:microtubule cytoskeleton
GO:0005643--C:nuclear pore
GO:0071561--C:nucleus-vacuole junction
GO:0034271--C:phosphatidylinositol 3-kinase complex, class III, type I
GO:0034272--C:phosphatidylinositol 3-kinase complex, class III, type II
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0045324--P:late endosome to vacuole transport
GO:0016236--P:macroautophagy
GO:0030242--P:pexophagy
GO:0043552--P:positive regulation of phosphatidylinositol 3-kinase activity
GO:0006468--P:protein phosphorylation
GO:0006623--P:protein targeting to vacuole
GO:0032801--P:receptor catabolic process
GO:0032465--P:regulation of cytokinesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000213	Aegilops tauschii	29.30	3.00e-35	144.00
IUUC-Aml-001659	Ailuropoda melanoleuca	87.91	0.00e+00	2417.00
IUUC-Atr-002968	Amborella trichopoda	46.18	7.00e-48	186.00
IUUC-Apl-003418	Anas platyrhynchos	87.61	0.00e+00	2492.00
IUUC-Aca-004344	Anolis carolinensis	87.17	0.00e+00	2222.00
IUUC-Aly-006107	Arabidopsis lyrata	46.20	6.00e-72	265.00
IUUC-Ath-007260	Arabidopsis thaliana	46.50	1.00e-72	268.00
IUUC-Ago-007721	Ashbya gossypii	39.49	2.00e-58	221.00
IUUC-Acl-008378	Aspergillus clavatus	35.31	6.00e-133	468.00
IUUC-Afl-008632	Aspergillus flavus	33.55	7.00e-124	438.00
IUUC-Afu-009020	Aspergillus fumigatus	34.06	2.00e-125	443.00
IUUC-Ani-009204	Aspergillus nidulans	33.52	1.00e-119	424.00
IUUC-Ang-009811	Aspergillus niger	33.11	4.00e-124	439.00
IUUC-Aor-010168	Aspergillus oryzae	33.55	7.00e-124	438.00
IUUC-Ate-010556	Aspergillus terreus	34.24	7.00e-127	448.00
IUUC-Ame-011955	Astyanax mexicanus	76.07	0.00e+00	1704.00
IUUC-Bgr-012050	Blumeria graminis	33.96	3.00e-121	429.00
IUUC-Bta-012432	Bos taurus	86.81	0.00e+00	2440.00
IUUC-Bci-013846	Botrytis cinerea	32.32	3.00e-124	439.00
IUUC-Bdi-015072	Brachypodium distachyon	42.18	2.00e-68	254.00
IUUC-Bol-015314	Brassica oleracea	26.47	1.00e-78	288.00
IUUC-Bra-017476	Brassica rapa	46.50	3.00e-73	270.00
IUUC-Cel-018550	Caenorhabditis elegans	29.99	5.00e-74	272.00
IUUC-Cja-019538	Callithrix jacchus	87.25	0.00e+00	2446.00
IUUC-Cfa-020483	Canis familiaris	87.84	0.00e+00	2429.00
IUUC-Cpo-021392	Cavia porcellus	87.03	0.00e+00	2442.00
IUUC-Csa-024112	Chlorocebus sabaeus	87.84	0.00e+00	2462.00
IUUC-Cho-025015	Choloepus hoffmanni	85.63	0.00e+00	908.00
IUUC-Cin-025209	Ciona intestinalis	39.80	0.00e+00	1016.00
IUUC-Csv-026334	Ciona savignyi	39.75	0.00e+00	818.00
IUUC-Cgl-026447	Colletotrichum gloeosporioides	33.56	1.00e-123	438.00
IUUC-Cne-026999	Cryptococcus neoformans	34.84	2.00e-92	334.00
IUUC-Dre-028662	Danio rerio	77.51	0.00e+00	2194.00
IUUC-Dno-029545	Dasypus novemcinctus	85.86	0.00e+00	2388.00
IUUC-Dor-030941	Dipodomys ordii	70.58	0.00e+00	648.00
IUUC-Dse-031455	Dothistroma septosporum	34.41	4.00e-123	436.00
IUUC-Dme-031726	Drosophila melanogaster	38.17	0.00e+00	895.00
IUUC-Ete-033147	Echinops telfairi	77.36	0.00e+00	814.00
IUUC-Eca-034025	Equus caballus	87.91	0.00e+00	2458.00
IUUC-Eeu-034480	Erinaceus europaeus	82.20	0.00e+00	994.00
IUUC-Fca-035741	Felis catus	87.11	0.00e+00	2424.00
IUUC-Fal-037666	Ficedula albicollis	86.94	0.00e+00	2476.00
IUUC-Fox-037818	Fusarium oxysporum	32.43	2.00e-112	400.00
IUUC-Fso-038086	Fusarium solani	32.34	4.00e-116	412.00
IUUC-Gmo-038804	Gadus morhua	80.99	0.00e+00	743.00
IUUC-Ggr-039800	Gaeumannomyces graminis	33.89	7.00e-121	428.00
IUUC-Gga-041251	Gallus gallus	85.45	0.00e+00	1904.00
IUUC-Gac-042376	Gasterosteus aculeatus	74.60	0.00e+00	2110.00
IUUC-Gma-044095	Glycine max	43.88	2.00e-74	274.00
IUUC-Ggo-044506	Gorilla gorilla	87.34	0.00e+00	2442.00
IUUC-Hsa-045871	Homo sapiens	87.84	0.00e+00	2458.00
IUUC-Hvu-047648	Hordeum vulgare	27.82	6.00e-32	132.00
IUUC-Itr-048082	Ictidomys tridecemlineatus	84.03	0.00e+00	1016.00
IUUC-Kpa-049390	Komagataella pastoris	29.75	1.00e-111	397.00
IUUC-Lch-050284	Latimeria chalumnae	81.27	0.00e+00	2220.00
IUUC-Lpe-050880	Leersia perrieri	41.31	4.00e-66	246.00
IUUC-Loc-052815	Lepisosteus oculatus	77.68	0.00e+00	2196.00
IUUC-Lma-053324	Leptosphaeria maculans	32.85	1.00e-130	461.00
IUUC-Laf-054204	Loxodonta africana	76.31	0.00e+00	2058.00
IUUC-Mcc-054612	Macaca mulatta	87.69	0.00e+00	2453.00
IUUC-Meu-056227	Macropus eugenii	86.02	0.00e+00	839.00
IUUC-Mor-057094	Magnaporthe oryzae	33.93	4.00e-117	416.00
IUUC-Mtr-058550	Medicago truncatula	42.43	2.00e-73	271.00
IUUC-Mla-058893	Melampsora laricipopulina	32.15	4.00e-111	395.00
IUUC-Mga-059474	Meleagris gallopavo	86.75	0.00e+00	2340.00
IUUC-Mvi-060227	Microbotryum violaceum	46.34	1.00e-84	308.00
IUUC-Mmr-061543	Microcebus murinus	80.51	0.00e+00	2176.00
IUUC-Mdo-062129	Monodelphis domestica	89.54	0.00e+00	2433.00
IUUC-Mmu-064381	Mus musculus	85.93	0.00e+00	2413.00
IUUC-Mac-064455	Musa acuminata	36.30	3.00e-110	392.00
IUUC-Mpu-066151	Mustela putorius furo	94.42	0.00e+00	937.00
IUUC-Mlu-067824	Myotis lucifugus	87.84	0.00e+00	2457.00
IUUC-Nfi-068241	Neosartorya fischeri	34.98	8.00e-130	458.00
IUUC-Ncr-068964	Neurospora crassa	33.68	2.00e-122	433.00
IUUC-Nle-069152	Nomascus leucogenys	87.69	0.00e+00	2453.00
IUUC-Opr-070870	Ochotona princeps	73.79	0.00e+00	1224.00
IUUC-Ont-071293	Oreochromis niloticus	76.27	0.00e+00	2150.00
IUUC-Ocu-074727	Oryctolagus cuniculus	87.69	0.00e+00	2424.00
IUUC-Oba-075932	Oryza barthii	37.38	7.00e-66	245.00
IUUC-Obr-076424	Oryza brachyantha	46.45	4.00e-64	239.00
IUUC-Ogl-077491	Oryza glaberrima	37.38	7.00e-66	245.00
IUUC-Ogu-078933	Oryza glumaepatula	45.03	3.00e-69	256.00
IUUC-Oin-079604	Oryza indica	41.29	3.00e-71	263.00
IUUC-Olo-080850	Oryza longistaminata	33.58	3.00e-103	369.00
IUUC-Ome-081860	Oryza meridionalis	41.29	3.00e-71	263.00
IUUC-Oni-082895	Oryza nivara	37.38	2.00e-65	243.00
IUUC-Opu-083741	Oryza punctata	41.29	2.00e-70	260.00
IUUC-Oru-084616	Oryza rufipogon	37.11	5.00e-65	243.00
IUUC-Osa-085941	Oryza sativa	28.27	1.00e-35	144.00
IUUC-Ola-087357	Oryzias latipes	86.13	6.00e-163	565.00
IUUC-Olu-087659	Ostreococcus lucimarinus	28.94	3.00e-77	283.00
IUUC-Oga-088555	Otolemur garnettii	87.77	0.00e+00	2441.00
IUUC-Oar-089304	Ovis aries	82.84	0.00e+00	1135.00
IUUC-Ptr-091140	Pan troglodytes	87.77	0.00e+00	2456.00
IUUC-Pan-092413	Papio anubis	86.97	0.00e+00	2340.00
IUUC-Psi-093210	Pelodiscus sinensis	87.97	0.00e+00	2496.00
IUUC-Pma-094674	Petromyzon marinus	54.83	0.00e+00	719.00
IUUC-Pno-094969	Phaeosphaeria nodorum	29.61	3.00e-131	462.00
IUUC-Ppa-096017	Physcomitrella patens	42.86	5.00e-79	289.00
IUUC-Pfo-096077	Poecilia formosa	75.20	0.00e+00	2106.00
IUUC-Pab-098269	Pongo abelii	86.96	0.00e+00	2440.00
IUUC-Pop-100052	Populus trichocarpa	43.09	2.00e-65	244.00
IUUC-Pca-100377	Procavia capensis	82.37	0.00e+00	2189.00
IUUC-Ppe-101445	Prunus persica	42.93	3.00e-74	273.00
IUUC-Pva-102198	Pteropus vampyrus	84.25	0.00e+00	1536.00
IUUC-Pgr-103544	Puccinia graminis	48.58	1.00e-84	308.00
IUUC-Ptt-103964	Puccinia triticina	48.26	9.00e-82	298.00
IUUC-Pte-104196	Pyrenophora teres	33.29	5.00e-126	445.00
IUUC-Pyt-104544	Pyrenophora triticirepentis	32.98	2.00e-124	439.00
IUUC-Rno-105256	Rattus norvegicus	86.15	0.00e+00	2417.00
IUUC-Sce-106295	Saccharomyces cerevisiae	40.24	5.00e-72	266.00
IUUC-Sha-107597	Sarcophilus harrisii	89.38	0.00e+00	2474.00
IUUC-Sja-107781	Schizosaccharomyces japonicus	42.30	2.00e-73	270.00
IUUC-Spo-108031	Schizosaccharomyces pombe	44.28	4.00e-75	276.00
IUUC-Ssl-108579	Sclerotinia sclerotiorum	33.45	7.00e-118	418.00
IUUC-Smo-108679	Selaginella moellendorffii	43.58	7.00e-79	288.00
IUUC-Sit-110765	Setaria italica	40.67	2.00e-65	244.00
IUUC-Sly-111527	Solanum lycopersicum	43.49	4.00e-74	273.00
IUUC-Stu-112899	Solanum tuberosum	43.49	3.00e-74	273.00
IUUC-Sar-112986	Sorex araneus	86.89	0.00e+00	2430.00
IUUC-Sbi-114604	Sorghum bicolor	41.33	1.00e-69	258.00
IUUC-Sre-115191	Sporisorium reilianum	44.44	5.00e-69	256.00
IUUC-Ssc-115440	Sus scrofa	86.82	0.00e+00	2409.00
IUUC-Tgu-116633	Taeniopygia guttata	87.45	0.00e+00	2487.00
IUUC-Tru-118439	Takifugu rubripes	74.14	0.00e+00	2111.00
IUUC-Tsy-119472	Tarsius syrichta	76.80	0.00e+00	1202.00
IUUC-Tni-119808	Tetraodon nigroviridis	70.06	0.00e+00	1912.00
IUUC-Tca-121648	Theobroma cacao	44.60	1.00e-75	278.00
IUUC-Tre-122161	Trichoderma reesei	31.67	2.00e-104	374.00
IUUC-Tvi-122575	Trichoderma virens	31.81	4.00e-97	349.00
IUUC-Tae-123381	Triticum aestivum	45.62	2.00e-69	257.00
IUUC-Tur-126291	Triticum urartu	43.02	1.00e-69	258.00
IUUC-Tme-126979	Tuber melanosporum	34.26	9.00e-135	474.00
IUUC-Tbe-127576	Tupaia belangeri	92.20	0.00e+00	895.00
IUUC-Ttr-129106	Tursiops truncatus	84.31	0.00e+00	1121.00
IUUC-Uma-129633	Ustilago maydis	44.06	3.00e-77	283.00
IUUC-Vda-130001	Verticillium dahliae	30.91	3.00e-104	373.00
IUUC-Vpa-130733	Vicugna pacos	74.25	0.00e+00	1067.00
IUUC-Vvi-131318	Vitis vinifera	42.25	3.00e-72	266.00
IUUC-Xtr-131908	Xenopus tropicalis	81.88	0.00e+00	2333.00
IUUC-Xma-133331	Xiphophorus maculatus	75.71	0.00e+00	2125.00
IUUC-Yli-134651	Yarrowia lipolytica	34.73	1.00e-105	377.00
IUUC-Zma-135850	Zea mays	40.00	8.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence