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Tag Content
UUCD2 ID IUUC-Mcc-055601
UUCD1 version UUC-MaM-00773
Ensembl Protein ID ENSMMUP00000026124.2
UniProt Accession F7GTB6; F7GTB6_MACMU
Genbank Protein ID AFE78620.1; AFH32692.1; AFI37362.1
Protein Name Fizzy-related protein homolog isoform 2
Genbank Nucleotide ID JSUE03020267; JU475888; JV047291
Gene Name FZR1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000019870.3 ENSMMUT00000027923.3 ENSMMUP00000026124.2
ENSMMUG00000019870.3 ENSMMUT00000014019.3 ENSMMUP00000013128.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-26 92.3 311 341
E3 adaptor/Cullin RING/APC_C/CDC20 1.20e-150 502.0 175 479
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWD 29
           gH  +v++l++ +d  ll+sG++D+++ vW+
   Q: 311  GHRQEVCGLKWsTDhQLLASGGNDNKLLVWN 341
           8**********98889**************9 PP
   

   E3 adaptor/Cullin RING/APC_C/CDC20
   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladl.eekdlvtsvswieegtllavGtkkgeveiyDveekkk 88
           p+kvldapel+ddfylnL+dWss nvl+v+Lg++vylwsa+t++v++l+dl  e+d+vtsv w+e+g+l+avGt+kg v+i+D+++ kk
   Q: 175  PFKVLDAPELQDDFYLNLVDWSSLNVLSVGLGTCVYLWSACTSQVTRLCDLsVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKK 263
           689************************************************99************************************ PP
   S: 89   vrtltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelkl.stlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfk 176
           +++l+gh+arvgaL+Wnae+lssGsrd++il+rd+r++ l+  ++lq+h+qevCGlkw++d++lLasGGnDn++ vw++ss +P+++++
   Q: 264  LSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSeRRLQGHRQEVCGLKWSTDHQLLASGGNDNKLLVWNHSSLSPVQQYT 352
           ******************************************99********************************************* PP
   S: 177  ehkaavkaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkg 265
           eh aavkaiawsP+q++lLasGGGtaDrci+fwntltg+ l++idtgsqvc+l+wsk+++elvsthG+++n+i +wkypsl++va+l+g
   Q: 353  EHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTG 441
           ***************************************************************************************** PP
   S: 266  heaRvlslalspdgeaivtaagDetlrfwklfdkkkak 303
           h++Rvl+la+spdgeaivt+agDetlrfw++f+k++++
   Q: 442  HSYRVLYLAMSPDGEAIVTGAGDETLRFWNVFSKTRST 479
           *********************************99875 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MDQDYERRLL RQIVIQNENT MPRVTEMRRT LTPASSPVSS PSKHGDRFIP SRAGANWSVN 60
FHRINENEKS PSQNRKAKDA TSDNGKDGLA YSALLKNELL GAGIEKVQDP QTEDRRLQPS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055601|E3,WD_repeat;E3,CDC20|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCGCGGCC GGCTGGGCGC GCGCGGCGGA GGGAGGGAGC CGGGAGGCAG CGGAGGAGCG 60
ACCGCCGCCA TATTAGGGAC CGCGGAGCCC GGGAGCCCGT CAGCGGCGGC TGCGGCCGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055601|E3,WD_repeat;E3,CDC20|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0031572--P:G2 DNA damage checkpoint
GO:0070306--P:lens fiber cell differentiation
GO:0090344--P:negative regulation of cell aging
GO:0008284--P:positive regulation of cell proliferation
GO:0045732--P:positive regulation of protein catabolic process
GO:1904668--P:positive regulation of ubiquitin protein ligase activity
GO:0040020--P:regulation of meiotic nuclear division
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000670 Aegilops tauschii 64.19 1.00e-114 406.00
IUUC-Aml-002003 Ailuropoda melanoleuca 94.35 0.00e+00 927.00
IUUC-Atr-002753 Amborella trichopoda 57.40 1.00e-132 466.00
IUUC-Apl-003212 Anas platyrhynchos 97.97 0.00e+00 983.00
IUUC-Aly-005442 Arabidopsis lyrata 57.47 3.00e-139 488.00
IUUC-Ath-006938 Arabidopsis thaliana 57.83 1.00e-137 483.00
IUUC-Ago-007784 Ashbya gossypii 49.42 1.00e-96 347.00
IUUC-Acl-008269 Aspergillus clavatus 49.79 9.00e-133 467.00
IUUC-Afl-008432 Aspergillus flavus 50.21 4.00e-132 464.00
IUUC-Afu-008829 Aspergillus fumigatus 50.62 1.00e-133 469.00
IUUC-Ani-009471 Aspergillus nidulans 49.79 1.00e-131 463.00
IUUC-Ang-009711 Aspergillus niger 51.06 9.00e-131 460.00
IUUC-Aor-010118 Aspergillus oryzae 50.21 4.00e-132 464.00
IUUC-Ate-010534 Aspergillus terreus 50.62 1.00e-131 463.00
IUUC-Ame-011011 Astyanax mexicanus 92.56 0.00e+00 885.00
IUUC-Bgr-012013 Blumeria graminis 50.51 4.00e-131 461.00
IUUC-Bta-012586 Bos taurus 98.99 0.00e+00 1009.00
IUUC-Bci-013807 Botrytis cinerea 51.65 6.00e-126 444.00
IUUC-Bdi-014981 Brachypodium distachyon 70.49 3.00e-129 455.00
IUUC-Bol-016301 Brassica oleracea 57.01 1.00e-137 483.00
IUUC-Bra-017453 Brassica rapa 57.01 8.00e-138 483.00
IUUC-Cel-018472 Caenorhabditis elegans 65.24 6.00e-143 501.00
IUUC-Cja-019929 Callithrix jacchus 99.19 0.00e+00 989.00
IUUC-Cfa-020977 Canis familiaris 98.19 0.00e+00 981.00
IUUC-Cpo-021537 Cavia porcellus 98.78 0.00e+00 1008.00
IUUC-Csa-023389 Chlorocebus sabaeus 100.00 0.00e+00 1019.00
IUUC-Cin-025327 Ciona intestinalis 69.65 0.00e+00 630.00
IUUC-Csv-025921 Ciona savignyi 66.10 0.00e+00 662.00
IUUC-Cgl-026631 Colletotrichum gloeosporioides 51.53 2.00e-132 466.00
IUUC-Cne-026933 Cryptococcus neoformans 59.58 9.00e-128 451.00
IUUC-Cme-027143 Cyanidioschyzon merolae 63.70 2.00e-118 420.00
IUUC-Dre-027470 Danio rerio 91.13 0.00e+00 876.00
IUUC-Dno-029629 Dasypus novemcinctus 90.07 0.00e+00 800.00
IUUC-Dor-030187 Dipodomys ordii 87.70 0.00e+00 873.00
IUUC-Dse-031502 Dothistroma septosporum 50.21 2.00e-126 446.00
IUUC-Dme-031858 Drosophila melanogaster 74.44 0.00e+00 683.00
IUUC-Ete-032562 Echinops telfairi 85.60 0.00e+00 831.00
IUUC-Eca-034210 Equus caballus 98.99 0.00e+00 1009.00
IUUC-Fca-035839 Felis catus 93.51 0.00e+00 932.00
IUUC-Fal-036895 Ficedula albicollis 97.77 0.00e+00 981.00
IUUC-Fox-037814 Fusarium oxysporum 64.29 9.00e-124 436.00
IUUC-Fso-038420 Fusarium solani 50.10 3.00e-132 465.00
IUUC-Gmo-039544 Gadus morhua 89.11 0.00e+00 858.00
IUUC-Ggr-039774 Gaeumannomyces graminis 50.92 3.00e-132 465.00
IUUC-Gga-041025 Gallus gallus 97.77 0.00e+00 981.00
IUUC-Gac-041596 Gasterosteus aculeatus 90.32 0.00e+00 867.00
IUUC-Gma-042657 Glycine max 56.82 5.00e-135 474.00
IUUC-Ggo-045599 Gorilla gorilla 99.19 0.00e+00 954.00
IUUC-Hsa-046695 Homo sapiens 99.40 0.00e+00 991.00
IUUC-Hvu-047486 Hordeum vulgare 65.95 1.00e-106 379.00
IUUC-Itr-048192 Ictidomys tridecemlineatus 98.17 0.00e+00 1004.00
IUUC-Kpa-049239 Komagataella pastoris 58.50 2.00e-122 432.00
IUUC-Lch-049827 Latimeria chalumnae 96.35 0.00e+00 931.00
IUUC-Lpe-051568 Leersia perrieri 50.68 2.00e-111 395.00
IUUC-Loc-052856 Lepisosteus oculatus 94.14 0.00e+00 909.00
IUUC-Laf-054321 Loxodonta africana 91.56 4.00e-110 391.00
IUUC-Meu-056276 Macropus eugenii 68.35 2.00e-169 588.00
IUUC-Mor-057113 Magnaporthe oryzae 51.13 5.00e-132 464.00
IUUC-Mpo-057599 Magnaporthe poae 51.12 3.00e-132 465.00
IUUC-Mtr-057689 Medicago truncatula 57.11 7.00e-137 480.00
IUUC-Mla-059048 Melampsora laricipopulina 50.10 6.00e-120 424.00
IUUC-Mga-060097 Meleagris gallopavo 91.75 0.00e+00 909.00
IUUC-Mvi-060465 Microbotryum violaceum 51.98 1.00e-130 459.00
IUUC-Mmr-061151 Microcebus murinus 89.52 0.00e+00 857.00
IUUC-Mdo-063062 Monodelphis domestica 97.57 0.00e+00 981.00
IUUC-Mmu-063731 Mus musculus 98.38 0.00e+00 1004.00
IUUC-Mac-065208 Musa acuminata 57.70 2.00e-129 455.00
IUUC-Mpu-066173 Mustela putorius furo 98.58 0.00e+00 1008.00
IUUC-Mlu-068030 Myotis lucifugus 98.39 0.00e+00 983.00
IUUC-Nfi-068536 Neosartorya fischeri 50.62 4.00e-134 471.00
IUUC-Ncr-068734 Neurospora crassa 52.35 7.00e-135 474.00
IUUC-Nle-070163 Nomascus leucogenys 100.00 0.00e+00 1020.00
IUUC-Opr-070974 Ochotona princeps 92.12 5.00e-156 543.00
IUUC-Ont-072507 Oreochromis niloticus 87.07 0.00e+00 880.00
IUUC-Oan-073634 Ornithorhynchus anatinus 99.32 5.00e-175 606.00
IUUC-Oba-075417 Oryza barthii 62.86 5.00e-111 394.00
IUUC-Obr-076123 Oryza brachyantha 69.51 3.00e-126 445.00
IUUC-Ogl-077294 Oryza glaberrima 53.88 2.00e-126 445.00
IUUC-Ogu-077996 Oryza glumaepatula 53.66 4.00e-125 441.00
IUUC-Oin-080172 Oryza indica 70.16 3.00e-126 445.00
IUUC-Olo-081068 Oryza longistaminata 70.16 3.00e-126 444.00
IUUC-Ome-081250 Oryza meridionalis 54.34 1.00e-127 449.00
IUUC-Oni-083048 Oryza nivara 53.88 2.00e-126 445.00
IUUC-Opu-083333 Oryza punctata 54.29 8.00e-127 447.00
IUUC-Oru-085001 Oryza rufipogon 53.88 2.00e-126 445.00
IUUC-Osa-086243 Oryza sativa 53.88 2.00e-126 445.00
IUUC-Ola-087094 Oryzias latipes 89.42 0.00e+00 827.00
IUUC-Oga-088911 Otolemur garnettii 99.39 0.00e+00 1011.00
IUUC-Oar-089508 Ovis aries 98.99 0.00e+00 1009.00
IUUC-Ptr-090967 Pan troglodytes 87.56 0.00e+00 665.00
IUUC-Pan-092147 Papio anubis 99.40 0.00e+00 991.00
IUUC-Psi-093702 Pelodiscus sinensis 97.58 0.00e+00 979.00
IUUC-Pma-094581 Petromyzon marinus 83.86 0.00e+00 798.00
IUUC-Pno-095139 Phaeosphaeria nodorum 59.76 5.00e-113 401.00
IUUC-Ppa-095952 Physcomitrella patens 57.88 4.00e-141 494.00
IUUC-Pfo-096309 Poecilia formosa 90.93 0.00e+00 871.00
IUUC-Pab-098762 Pongo abelii 82.26 0.00e+00 768.00
IUUC-Pop-098924 Populus trichocarpa 57.21 8.00e-133 467.00
IUUC-Pca-100565 Procavia capensis 92.39 0.00e+00 867.00
IUUC-Ppe-101924 Prunus persica 57.31 2.00e-136 479.00
IUUC-Pva-102602 Pteropus vampyrus 96.16 0.00e+00 944.00
IUUC-Pgr-103466 Puccinia graminis 50.86 4.00e-118 418.00
IUUC-Ptt-103888 Puccinia triticina 53.71 1.00e-107 383.00
IUUC-Pte-104097 Pyrenophora teres 48.93 6.00e-129 454.00
IUUC-Pyt-104445 Pyrenophora triticirepentis 45.21 2.00e-111 396.00
IUUC-Rno-105028 Rattus norvegicus 97.97 0.00e+00 979.00
IUUC-Sce-106240 Saccharomyces cerevisiae 38.92 2.00e-95 343.00
IUUC-Sha-107107 Sarcophilus harrisii 83.40 0.00e+00 819.00
IUUC-Sja-107900 Schizosaccharomyces japonicus 48.64 6.00e-115 407.00
IUUC-Spo-108056 Schizosaccharomyces pombe 48.73 7.00e-114 404.00
IUUC-Ssl-108391 Sclerotinia sclerotiorum 52.49 8.00e-129 454.00
IUUC-Smo-108878 Selaginella moellendorffii 59.06 3.00e-144 504.00
IUUC-Sit-110550 Setaria italica 55.38 9.00e-128 450.00
IUUC-Sly-111446 Solanum lycopersicum 56.95 2.00e-134 472.00
IUUC-Stu-112491 Solanum tuberosum 56.73 1.00e-133 469.00
IUUC-Sar-112962 Sorex araneus 80.53 1.00e-119 422.00
IUUC-Sbi-114489 Sorghum bicolor 54.32 1.00e-123 436.00
IUUC-Sre-115222 Sporisorium reilianum 47.83 5.00e-132 464.00
IUUC-Ssc-116171 Sus scrofa 98.78 0.00e+00 1008.00
IUUC-Tgu-116878 Taeniopygia guttata 86.43 0.00e+00 842.00
IUUC-Tru-118222 Takifugu rubripes 89.78 0.00e+00 861.00
IUUC-Tni-119863 Tetraodon nigroviridis 90.52 0.00e+00 863.00
IUUC-Tca-121599 Theobroma cacao 55.08 7.00e-135 473.00
IUUC-Tre-122249 Trichoderma reesei 51.53 2.00e-133 469.00
IUUC-Tvi-122675 Trichoderma virens 51.73 2.00e-133 469.00
IUUC-Tae-123028 Triticum aestivum 58.59 5.00e-126 444.00
IUUC-Tur-126545 Triticum urartu 59.94 6.00e-104 370.00
IUUC-Tme-127151 Tuber melanosporum 54.77 1.00e-145 509.00
IUUC-Tbe-128056 Tupaia belangeri 89.38 2.00e-168 584.00
IUUC-Ttr-129055 Tursiops truncatus 97.58 0.00e+00 970.00
IUUC-Uma-129555 Ustilago maydis 47.64 1.00e-131 463.00
IUUC-Vda-130027 Verticillium dahliae 51.13 2.00e-133 469.00
IUUC-Vvi-131749 Vitis vinifera 55.53 5.00e-134 471.00
IUUC-Xtr-132808 Xenopus tropicalis 91.68 0.00e+00 924.00
IUUC-Xma-133183 Xiphophorus maculatus 90.93 0.00e+00 871.00
IUUC-Yli-134584 Yarrowia lipolytica 64.55 8.00e-131 461.00
IUUC-Zma-135640 Zea mays 68.04 3.00e-125 441.00
Created Date 25-Jun-2017

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