iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090440

Ensembl Protein ID

ENSOARP00000021574.1

UniProt Accession

W5QFS6; W5QFS6_SHEEP

Genbank Protein ID

ENSOARP00000021574

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01059330

Gene Name

UBE2N

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000020093.1	ENSOART00000021876.1	ENSOARP00000021574.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.40e-47	161.1	7	139

Active Site

Position(s)	Description	Evidence
87	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R+ ke+++l ++p++gi+a+p+++ +   ++v+i Gp+d+p+egg+Fkle+ +pe+YP+ +Pkv+f+tki+hPnv++ G++Cl+il+  
   Q: 7    RIIKETQRLLAEPVPGIKAEPDES-NARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILN-- 92
           899*********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkk 136
           +kWspal++++vllsiq+ll+ pnp++pl +++ae++k+n+++  ++
   Q: 93   DKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIET 139
           ****************************************9976655 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAGLPRRIIK ETQRLLAEPV PGIKAEPDES NARYFHVVIA GPQDSPFEGG TFKLELFLPE 60
EYPMAAPKVR FMTKIYHPNV DKLGRICLDI LNDKWSPALQ IRTVLLSIQA LLSAPNPDDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGGGC TGCCCCGTAG GATTATCAAG GAAACCCAGC GTTTGCTGGC AGAACCAGTT 60
CCCGGCATTA AAGCAGAACC AGATGAGAGC AACGCCCGTT ATTTTCATGT GGTCATTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0001650--C:fibrillar center
GO:0031372--C:UBC13-MMS2 complex
GO:0035370--C:UBC13-UEV1A complex
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0003723--F:RNA binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0000729--P:DNA double-strand break processing
GO:0000724--P:double-strand break repair via homologous recombination
GO:0016574--P:histone ubiquitination
GO:0045739--P:positive regulation of DNA repair
GO:0031058--P:positive regulation of histone modification
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0006301--P:postreplication repair
GO:0070534--P:protein K63-linked ubiquitination
GO:0033182--P:regulation of histone ubiquitination
GO:0050852--P:T cell receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

oas:105601864

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000100	Aegilops tauschii	78.91	1.00e-68	251.00
IUUC-Atr-002818	Amborella trichopoda	78.91	4.00e-69	253.00
IUUC-Apl-003469	Anas platyrhynchos	97.26	1.00e-82	298.00
IUUC-Aca-005051	Anolis carolinensis	99.34	6.00e-87	311.00
IUUC-Aly-006258	Arabidopsis lyrata	79.59	9.00e-70	255.00
IUUC-Ath-007639	Arabidopsis thaliana	78.91	3.00e-69	253.00
IUUC-Ago-007837	Ashbya gossypii	74.40	1.00e-53	201.00
IUUC-Acl-008263	Aspergillus clavatus	70.95	5.00e-63	233.00
IUUC-Afl-008733	Aspergillus flavus	71.62	3.00e-63	233.00
IUUC-Afu-008946	Aspergillus fumigatus	70.95	5.00e-63	233.00
IUUC-Ani-009482	Aspergillus nidulans	70.67	2.00e-63	234.00
IUUC-Ang-009678	Aspergillus niger	71.62	6.00e-63	232.00
IUUC-Aor-010025	Aspergillus oryzae	71.62	3.00e-63	233.00
IUUC-Ate-010254	Aspergillus terreus	70.55	7.00e-62	228.00
IUUC-Ame-010742	Astyanax mexicanus	97.37	5.00e-85	305.00
IUUC-Bgr-012156	Blumeria graminis	64.90	7.00e-54	202.00
IUUC-Bta-012636	Bos taurus	99.34	6.00e-87	311.00
IUUC-Bci-013761	Botrytis cinerea	71.81	2.00e-62	231.00
IUUC-Bdi-014796	Brachypodium distachyon	79.59	8.00e-70	255.00
IUUC-Bol-016613	Brassica oleracea	79.59	7.00e-70	255.00
IUUC-Bra-016938	Brassica rapa	79.59	7.00e-70	255.00
IUUC-Cel-018119	Caenorhabditis elegans	87.92	2.00e-74	270.00
IUUC-Cja-019108	Callithrix jacchus	99.34	6.00e-87	311.00
IUUC-Cfa-020561	Canis familiaris	98.68	3.00e-86	310.00
IUUC-Cpo-022280	Cavia porcellus	96.03	5.00e-83	299.00
IUUC-Cre-022978	Chlamydomonas reinhardtii	78.23	1.00e-66	244.00
IUUC-Csa-023860	Chlorocebus sabaeus	92.11	8.00e-80	288.00
IUUC-Cho-024459	Choloepus hoffmanni	99.34	6.00e-87	311.00
IUUC-Cin-025278	Ciona intestinalis	79.59	3.00e-68	249.00
IUUC-Csv-025952	Ciona savignyi	72.30	7.00e-60	222.00
IUUC-Cgl-026752	Colletotrichum gloeosporioides	70.75	7.00e-61	225.00
IUUC-Cme-027100	Cyanidioschyzon merolae	65.10	5.00e-56	209.00
IUUC-Dre-027814	Danio rerio	97.37	5.00e-85	305.00
IUUC-Dno-030059	Dasypus novemcinctus	97.37	4.00e-85	306.00
IUUC-Dse-031505	Dothistroma septosporum	67.35	4.00e-59	219.00
IUUC-Dme-032097	Drosophila melanogaster	79.47	6.00e-72	262.00
IUUC-Ete-032369	Echinops telfairi	99.34	6.00e-87	311.00
IUUC-Eca-033230	Equus caballus	99.34	6.00e-87	311.00
IUUC-Fal-036781	Ficedula albicollis	96.05	4.00e-84	303.00
IUUC-Fox-037840	Fusarium oxysporum	71.23	3.00e-60	223.00
IUUC-Fso-038118	Fusarium solani	71.23	2.00e-60	224.00
IUUC-Gmo-039561	Gadus morhua	92.76	3.00e-82	296.00
IUUC-Ggr-039807	Gaeumannomyces graminis	72.11	5.00e-62	229.00
IUUC-Gga-041024	Gallus gallus	99.34	6.00e-87	311.00
IUUC-Gac-042450	Gasterosteus aculeatus	91.39	2.00e-80	290.00
IUUC-Gma-043982	Glycine max	79.59	9.00e-70	255.00
IUUC-Ggo-044660	Gorilla gorilla	98.68	4.00e-86	309.00
IUUC-Hsa-045881	Homo sapiens	99.34	6.00e-87	311.00
IUUC-Hvu-047346	Hordeum vulgare	79.59	8.00e-70	255.00
IUUC-Itr-048350	Ictidomys tridecemlineatus	91.45	6.00e-78	282.00
IUUC-Kpa-049285	Komagataella pastoris	69.59	3.00e-62	230.00
IUUC-Lpe-051394	Leersia perrieri	79.59	1.00e-69	254.00
IUUC-Loc-052205	Lepisosteus oculatus	97.37	4.00e-85	306.00
IUUC-Lma-053056	Leptosphaeria maculans	71.92	8.00e-62	228.00
IUUC-Mcc-054863	Macaca mulatta	99.34	6.00e-87	311.00
IUUC-Mor-057014	Magnaporthe oryzae	71.92	1.00e-60	224.00
IUUC-Mpo-057586	Magnaporthe poae	72.11	7.00e-62	229.00
IUUC-Mtr-058552	Medicago truncatula	71.43	8.00e-66	242.00
IUUC-Mla-058920	Melampsora laricipopulina	69.39	1.00e-60	225.00
IUUC-Mvi-060483	Microbotryum violaceum	74.83	2.00e-64	237.00
IUUC-Mmr-061167	Microcebus murinus	99.34	6.00e-87	311.00
IUUC-Mdo-062701	Monodelphis domestica	99.34	6.00e-87	311.00
IUUC-Mmu-064070	Mus musculus	99.34	6.00e-87	311.00
IUUC-Mac-064742	Musa acuminata	80.27	2.00e-70	257.00
IUUC-Mpu-066401	Mustela putorius furo	99.34	7.00e-87	311.00
IUUC-Mlu-067229	Myotis lucifugus	97.96	2.00e-82	297.00
IUUC-Nfi-068526	Neosartorya fischeri	70.95	4.00e-63	233.00
IUUC-Ncr-068643	Neurospora crassa	71.43	1.00e-61	228.00
IUUC-Nle-070146	Nomascus leucogenys	99.34	6.00e-87	311.00
IUUC-Opr-070232	Ochotona princeps	77.63	8.00e-63	232.00
IUUC-Ont-072369	Oreochromis niloticus	93.38	6.00e-82	295.00
IUUC-Oan-073174	Ornithorhynchus anatinus	95.39	6.00e-83	298.00
IUUC-Ocu-074712	Oryctolagus cuniculus	99.34	6.00e-87	311.00
IUUC-Oba-075408	Oryza barthii	79.59	1.00e-69	254.00
IUUC-Obr-076881	Oryza brachyantha	79.59	1.00e-69	254.00
IUUC-Ogl-077242	Oryza glaberrima	79.59	1.00e-69	254.00
IUUC-Ogu-078465	Oryza glumaepatula	79.59	1.00e-69	254.00
IUUC-Olo-080555	Oryza longistaminata	79.59	1.00e-69	254.00
IUUC-Ome-081653	Oryza meridionalis	79.59	1.00e-69	254.00
IUUC-Oni-082400	Oryza nivara	79.59	1.00e-69	254.00
IUUC-Opu-083130	Oryza punctata	79.71	9.00e-65	239.00
IUUC-Oru-084649	Oryza rufipogon	79.59	1.00e-69	254.00
IUUC-Osa-085629	Oryza sativa	79.59	1.00e-69	254.00
IUUC-Ola-087083	Oryzias latipes	94.00	1.00e-81	295.00
IUUC-Olu-087886	Ostreococcus lucimarinus	67.35	4.00e-58	216.00
IUUC-Oga-088983	Otolemur garnettii	95.33	2.00e-82	297.00
IUUC-Ptr-090572	Pan troglodytes	99.34	6.00e-87	311.00
IUUC-Pan-092503	Papio anubis	97.37	4.00e-85	306.00
IUUC-Pno-094838	Phaeosphaeria nodorum	71.62	8.00e-63	232.00
IUUC-Ppa-096014	Physcomitrella patens	81.51	3.00e-70	256.00
IUUC-Pfo-096074	Poecilia formosa	94.67	3.00e-82	296.00
IUUC-Pab-097778	Pongo abelii	99.34	6.00e-87	311.00
IUUC-Pop-099707	Populus trichocarpa	79.59	1.00e-69	254.00
IUUC-Pca-100334	Procavia capensis	82.89	2.00e-72	264.00
IUUC-Ppe-101149	Prunus persica	79.59	9.00e-70	255.00
IUUC-Pva-102979	Pteropus vampyrus	99.34	6.00e-87	311.00
IUUC-Pgr-103654	Puccinia graminis	70.07	5.00e-60	222.00
IUUC-Ptt-103752	Puccinia triticina	68.75	1.00e-57	214.00
IUUC-Pte-104137	Pyrenophora teres	70.55	4.00e-61	226.00
IUUC-Pyt-104513	Pyrenophora triticirepentis	70.55	4.00e-61	226.00
IUUC-Rno-105927	Rattus norvegicus	98.68	2.00e-86	310.00
IUUC-Sce-106178	Saccharomyces cerevisiae	69.59	5.00e-61	226.00
IUUC-Sha-107493	Sarcophilus harrisii	99.34	6.00e-87	311.00
IUUC-Sja-107878	Schizosaccharomyces japonicus	66.23	4.00e-57	213.00
IUUC-Spo-108062	Schizosaccharomyces pombe	68.03	3.00e-56	210.00
IUUC-Ssl-108395	Sclerotinia sclerotiorum	70.27	7.00e-61	225.00
IUUC-Smo-109587	Selaginella moellendorffii	74.00	3.00e-63	233.00
IUUC-Sit-110151	Setaria italica	79.59	1.00e-69	255.00
IUUC-Sly-111322	Solanum lycopersicum	79.59	7.00e-70	255.00
IUUC-Stu-112722	Solanum tuberosum	78.91	3.00e-69	253.00
IUUC-Sbi-114864	Sorghum bicolor	79.59	3.00e-69	253.00
IUUC-Sre-114927	Sporisorium reilianum	77.40	2.00e-66	243.00
IUUC-Ssc-116096	Sus scrofa	99.34	6.00e-87	311.00
IUUC-Tru-117903	Takifugu rubripes	93.38	4.00e-81	292.00
IUUC-Tni-120038	Tetraodon nigroviridis	93.38	4.00e-81	292.00
IUUC-Tca-121752	Theobroma cacao	79.86	3.00e-65	240.00
IUUC-Tre-121979	Trichoderma reesei	73.29	1.00e-61	228.00
IUUC-Tvi-122515	Trichoderma virens	72.60	6.00e-61	225.00
IUUC-Tae-125309	Triticum aestivum	79.59	8.00e-70	255.00
IUUC-Tme-127129	Tuber melanosporum	73.29	2.00e-62	230.00
IUUC-Ttr-128808	Tursiops truncatus	96.05	2.00e-83	300.00
IUUC-Uma-129548	Ustilago maydis	78.08	5.00e-67	245.00
IUUC-Vda-129810	Verticillium dahliae	70.55	3.00e-60	223.00
IUUC-Vpa-130221	Vicugna pacos	91.37	3.00e-69	253.00
IUUC-Vvi-131416	Vitis vinifera	65.73	6.00e-65	239.00
IUUC-Xtr-132366	Xenopus tropicalis	96.10	7.00e-84	302.00
IUUC-Xma-132986	Xiphophorus maculatus	93.38	1.00e-81	295.00
IUUC-Yli-134605	Yarrowia lipolytica	72.30	4.00e-63	233.00
IUUC-Zma-135587	Zea mays	76.32	2.00e-67	247.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence