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Tag Content
iUUCD ID IUUC-Pyt-104780
Ensembl Protein ID EDU40967
UniProt Accession B2VWG7; LIS1_PYRTR
Genbank Protein ID EDU40967.1
Protein Name Nuclear distribution protein PAC1; Lissencephaly-1 homolog; nudF homolog
Genbank Nucleotide ID DS231615
Gene Name pac1; lis1; PTRG_01529
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
PTRG_01529 EDU40967 EDU40967
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-48 159.4 200 247
UBD/Beta-Prp 1.50e-66 223.9 112 407
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.........sd.tllvsGsdDgtikvWDlrtgvllks 38
    gH sv++++f s+ +llvs+s+D+t+++WD++tg ++k+
   Q: 200 GHDHSVSAIRFvpsgaagspSSgNLLVSASRDKTLRIWDVTTGYCVKT 247
    8******************8557********************99875 PP
   


   UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk..ilvtgseDrtikvwdls.tgkcvhtlkghedsvlslsfsp 104
    ++h s+itcv+f+p s la+gs+d tik+wd++ g l r+++gh+++v +v+f + +l+++s+D tik+wd+s +k ++tl gh++sv +++f p
   Q: 112 QSHRSPITCVAFHPVFSSLASGSEDTTIKIWDWELGELERTVKGHTKGVLDVDFGGPRGgtLLASCSSDLTIKLWDPSdEYKNIRTLPGHDHSVSAIRFVP 212
    56788*************************************************8544446**************887699******************** PP
   S: 105 ........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.......... 187
    sg+ lvs+s+d+t+r+wd+ tg+c++ t +gh ++v+ v+ + dg+ l s+++D+t rlWd ++g+ t+ g h++ v++++
   Q: 213 sgaagspsSGNLLVSASRDKTLRIWDVTTGYCVK-TIRGHADWVRDVAPSFDGRWLLSAGNDQTARLWDASSGEPKCTFIG-HEHVVECVTiappvsyanl 311
    9999999888************************.*********************************************9.*********8888777777 PP
   S: 188 ...........fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl.rsgdllktlqlhnssvisvav 272
    ++s+ +++++gs+d+t+k+wd +g+ ++tl+gh+++++s+ f+p +++l+s+s+D++ir+Wdl + g ++kt++ + +++s+
   Q: 312 aslaglkkpppLSSSAEYIATGSRDKTIKIWDG-RGTLIKTLTGHDNWIRSLVFHPGGKYLLSASDDKTIRCWDLtQEGRCVKTVTDAHGHFVSCMR 407
    6666666666666666****************9.8889************************************83579********9977777655 PP
   

Organism Pyrenophora triticirepentis
Functional Description
(View)

Functional Description



     Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs.
Protein Sequence
(Fasta)
MSAILTDRQA EELHKAIIAY LGVINAPKTA EAFREEANVS ANFDDATRKK YEGLLEKKWT 60
SVVRLQKKVM ELEQRNQTLQ SELDSTTPTS LLRRNQDPAS WLPRAPARHT LQSHRSPITC 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Pyt-104780|E3,WD_repeat;UBD,Beta-Prp|Pyrenophora triticirepentis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAGCGCGA TATTGACGGA CCGGCAAGCC GAGGAGTTGT GAGTCTTGCG AGTCGCGGCA 60
CATGTGGGGA GCAACCACTA ACGGCGATGC AGGCACAAGG CCATTATTGC ATATTTAGGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Pyt-104780|E3,WD_repeat;UBD,Beta-Prp|Pyrenophora triticirepentis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR017252--Dynein_regulator_LIS1
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0007067--P:mitotic nuclear division
GO:0006810--P:transport

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001589 Ailuropoda melanoleuca 47.68 1.00e-104 371.00
IUUC-Apl-004024 Anas platyrhynchos 47.73 5.00e-108 382.00
IUUC-Aca-004564 Anolis carolinensis 47.49 6.00e-106 375.00
IUUC-Ago-007862 Ashbya gossypii 29.16 6.00e-42 163.00
IUUC-Acl-008360 Aspergillus clavatus 73.02 0.00e+00 670.00
IUUC-Afl-008502 Aspergillus flavus 62.95 2.00e-162 563.00
IUUC-Afu-008848 Aspergillus fumigatus 74.36 0.00e+00 717.00
IUUC-Ani-009173 Aspergillus nidulans 60.30 1.00e-169 587.00
IUUC-Ang-009873 Aspergillus niger 59.48 1.00e-162 564.00
IUUC-Aor-009973 Aspergillus oryzae 60.13 7.00e-157 545.00
IUUC-Ate-010523 Aspergillus terreus 60.43 1.00e-165 574.00
IUUC-Ame-010969 Astyanax mexicanus 47.68 1.00e-106 377.00
IUUC-Bgr-011972 Blumeria graminis 73.16 0.00e+00 712.00
IUUC-Bta-013106 Bos taurus 47.73 5.00e-108 382.00
IUUC-Bci-013615 Botrytis cinerea 76.99 0.00e+00 719.00
IUUC-Cel-018459 Caenorhabditis elegans 43.58 9.00e-95 338.00
IUUC-Cja-018755 Callithrix jacchus 46.78 7.00e-105 372.00
IUUC-Cfa-020749 Canis familiaris 47.73 5.00e-108 382.00
IUUC-Cpo-022371 Cavia porcellus 47.73 5.00e-108 382.00
IUUC-Csa-023524 Chlorocebus sabaeus 47.59 5.00e-90 322.00
IUUC-Cho-024764 Choloepus hoffmanni 45.38 2.00e-89 320.00
IUUC-Cin-025753 Ciona intestinalis 47.95 4.00e-101 359.00
IUUC-Csv-025817 Ciona savignyi 46.75 4.00e-104 369.00
IUUC-Cgl-026529 Colletotrichum gloeosporioides 75.38 0.00e+00 689.00
IUUC-Cne-027087 Cryptococcus neoformans 53.33 6.00e-118 415.00
IUUC-Dre-028314 Danio rerio 47.19 1.00e-105 374.00
IUUC-Dno-029050 Dasypus novemcinctus 47.73 4.00e-108 382.00
IUUC-Dor-030222 Dipodomys ordii 44.55 9.00e-99 351.00
IUUC-Dse-031164 Dothistroma septosporum 69.87 0.00e+00 665.00
IUUC-Dme-031745 Drosophila melanogaster 48.16 3.00e-100 357.00
IUUC-Ete-032508 Echinops telfairi 47.87 1.00e-71 261.00
IUUC-Eca-034288 Equus caballus 47.19 3.00e-103 366.00
IUUC-Eeu-034984 Erinaceus europaeus 44.31 1.00e-97 348.00
IUUC-Fca-036498 Felis catus 47.73 5.00e-108 382.00
IUUC-Fal-036920 Ficedula albicollis 47.73 5.00e-108 382.00
IUUC-Fox-037996 Fusarium oxysporum 69.55 0.00e+00 664.00
IUUC-Fso-038160 Fusarium solani 67.60 0.00e+00 633.00
IUUC-Gmo-038983 Gadus morhua 47.02 3.00e-106 376.00
IUUC-Ggr-040051 Gaeumannomyces graminis 67.60 0.00e+00 633.00
IUUC-Gga-040623 Gallus gallus 47.73 5.00e-108 382.00
IUUC-Gac-041613 Gasterosteus aculeatus 46.86 7.00e-106 375.00
IUUC-Ggo-045410 Gorilla gorilla 44.27 4.00e-87 313.00
IUUC-Hsa-046358 Homo sapiens 47.73 3.00e-108 383.00
IUUC-Itr-047890 Ictidomys tridecemlineatus 47.73 5.00e-108 382.00
IUUC-Kpa-049351 Komagataella pastoris 32.18 1.00e-50 192.00
IUUC-Lch-049936 Latimeria chalumnae 47.49 3.00e-107 379.00
IUUC-Loc-052476 Lepisosteus oculatus 47.43 1.00e-103 368.00
IUUC-Lma-053170 Leptosphaeria maculans 91.96 0.00e+00 820.00
IUUC-Laf-053713 Loxodonta africana 47.82 2.00e-105 374.00
IUUC-Mcc-054628 Macaca mulatta 47.73 8.00e-108 381.00
IUUC-Meu-055927 Macropus eugenii 40.43 2.00e-52 197.00
IUUC-Mor-056962 Magnaporthe oryzae 67.67 0.00e+00 648.00
IUUC-Mpo-057583 Magnaporthe poae 67.81 6.00e-178 615.00
IUUC-Mla-058819 Melampsora laricipopulina 48.61 1.00e-118 417.00
IUUC-Mga-059945 Meleagris gallopavo 47.49 1.00e-107 381.00
IUUC-Mvi-060403 Microbotryum violaceum 51.07 3.00e-132 462.00
IUUC-Mmr-061289 Microcebus murinus 47.68 1.00e-104 371.00
IUUC-Mdo-061912 Monodelphis domestica 47.73 1.00e-107 380.00
IUUC-Mmu-063253 Mus musculus 47.73 5.00e-108 382.00
IUUC-Mpu-066638 Mustela putorius furo 47.73 5.00e-108 382.00
IUUC-Mlu-067267 Myotis lucifugus 46.99 1.00e-104 371.00
IUUC-Nfi-068571 Neosartorya fischeri 68.95 0.00e+00 657.00
IUUC-Ncr-068895 Neurospora crassa 73.76 0.00e+00 674.00
IUUC-Nle-069087 Nomascus leucogenys 47.32 1.00e-88 317.00
IUUC-Opr-070579 Ochotona princeps 47.73 4.00e-108 382.00
IUUC-Ont-072432 Oreochromis niloticus 47.26 6.00e-107 379.00
IUUC-Oan-073072 Ornithorhynchus anatinus 47.73 5.00e-108 382.00
IUUC-Ocu-074180 Oryctolagus cuniculus 47.73 4.00e-108 382.00
IUUC-Ola-086815 Oryzias latipes 47.26 2.00e-106 377.00
IUUC-Oga-088219 Otolemur garnettii 46.78 3.00e-105 373.00
IUUC-Oar-090394 Ovis aries 47.73 5.00e-108 382.00
IUUC-Ptr-091517 Pan troglodytes 47.73 5.00e-108 382.00
IUUC-Pan-092421 Papio anubis 47.73 8.00e-108 381.00
IUUC-Psi-093370 Pelodiscus sinensis 47.73 9.00e-108 381.00
IUUC-Pma-094319 Petromyzon marinus 47.29 2.00e-88 317.00
IUUC-Pno-094815 Phaeosphaeria nodorum 93.72 0.00e+00 854.00
IUUC-Pfo-097089 Poecilia formosa 47.26 2.00e-106 377.00
IUUC-Pab-098421 Pongo abelii 47.73 5.00e-108 382.00
IUUC-Pca-100120 Procavia capensis 39.71 4.00e-63 233.00
IUUC-Pva-102960 Pteropus vampyrus 47.49 1.00e-106 378.00
IUUC-Pgr-103538 Puccinia graminis 50.85 2.00e-124 437.00
IUUC-Ptt-103990 Puccinia triticina 41.92 6.00e-42 164.00
IUUC-Pte-104261 Pyrenophora teres 99.57 0.00e+00 896.00
IUUC-Rno-105123 Rattus norvegicus 47.73 5.00e-108 382.00
IUUC-Sce-106208 Saccharomyces cerevisiae 29.11 1.00e-39 155.00
IUUC-Sha-107010 Sarcophilus harrisii 47.73 9.00e-108 381.00
IUUC-Sja-107899 Schizosaccharomyces japonicus 37.41 2.00e-69 254.00
IUUC-Ssl-108571 Sclerotinia sclerotiorum 77.75 0.00e+00 692.00
IUUC-Sar-113309 Sorex araneus 46.94 6.00e-102 362.00
IUUC-Sre-115003 Sporisorium reilianum 49.57 4.00e-126 442.00
IUUC-Ssc-116148 Sus scrofa 47.73 5.00e-108 382.00
IUUC-Tgu-117299 Taeniopygia guttata 47.73 6.00e-108 382.00
IUUC-Tru-117721 Takifugu rubripes 46.78 3.00e-106 376.00
IUUC-Tsy-119493 Tarsius syrichta 47.49 2.00e-106 377.00
IUUC-Tni-120355 Tetraodon nigroviridis 46.86 2.00e-105 373.00
IUUC-Tre-121977 Trichoderma reesei 61.22 5.00e-166 575.00
IUUC-Tvi-122661 Trichoderma virens 63.38 5.00e-168 582.00
IUUC-Tme-127031 Tuber melanosporum 69.43 0.00e+00 634.00
IUUC-Tbe-127492 Tupaia belangeri 41.20 7.00e-49 186.00
IUUC-Ttr-128929 Tursiops truncatus 47.73 1.00e-107 381.00
IUUC-Uma-129347 Ustilago maydis 50.87 4.00e-126 442.00
IUUC-Vda-129837 Verticillium dahliae 73.06 0.00e+00 662.00
IUUC-Vpa-130532 Vicugna pacos 41.69 4.00e-87 313.00
IUUC-Xtr-131985 Xenopus tropicalis 47.73 1.00e-107 381.00
IUUC-Xma-133314 Xiphophorus maculatus 47.02 4.00e-106 376.00
IUUC-Yli-134403 Yarrowia lipolytica 42.03 2.00e-101 360.00
Created Date 25-Jun-2017

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