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Tag Content
iUUCD ID IUUC-Xtr-132954
Ensembl Protein ID ENSXETP00000024367.3
UniProt Accession F6R539; F6R539_XENTR
Genbank Protein ID ENSXETP00000024367
Protein Name Non-specific serine/threonine protein kinase
Genbank Nucleotide ID AAMC01002200
Gene Name prkaa2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSXETG00000011138.3 ENSXETT00000024367.3 ENSXETP00000024367.3
ENSXETG00000011138.3 ENSXETT00000066254.1 ENSXETP00000062540.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 48.07 2.00e-123 439.00 IUUC-Ath-007014
UBD/Alpha-Helix/UBA 41.65 3.00e-108 386.00 IUUC-Spo-108202
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Xenopus tropicalis
Protein Sequence
(Fasta)
MAEKQKHDGR VKIGHYILGD TLGVGTFGKV KRLGEHQLTG HKVAVKILNR QKIRNLDVVG 60
KIKREIQNLK LFRHPHIIKL YQVISTPTDF FMVMEYVSGG ELFDYICKHG RVEEAEARRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Xtr-132954|UBD,UBA|Xenopus tropicalis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCTGAGA AGCAGAAGCA CGATGGACGG GTTAAAATAG GACACTACAT CTTGGGTGAC 60
ACGCTAGGAG TTGGCACCTT CGGAAAAGTG AAAAGCTGAG TATATTCTCC AGAGCTTTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Xtr-132954|UBD,UBA|Xenopus tropicalis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
Interpro

IPR032270--AMPK_C
IPR028375--KA1/Ssp2_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
Pfam

PF16579--AdenylateSensor
PF00069--Pkinase
SMART

SM00220--S_TKc
Gene Ontology

GO:0005737--C:cytoplasm
GO:0031588--C:nucleotide-activated protein kinase complex
GO:0005634--C:nucleus
GO:0004679--F:AMP-activated protein kinase activity
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0042149--P:cellular response to glucose starvation
GO:0035404--P:histone-serine phosphorylation
GO:0035556--P:intracellular signal transduction
GO:0032007--P:negative regulation of TOR signaling
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000713 Aegilops tauschii 48.05 6.00e-121 427.00
IUUC-Aml-001907 Ailuropoda melanoleuca 74.01 0.00e+00 791.00
IUUC-Atr-002770 Amborella trichopoda 47.67 4.00e-123 434.00
IUUC-Apl-003395 Anas platyrhynchos 92.90 0.00e+00 1016.00
IUUC-Aca-004480 Anolis carolinensis 92.03 0.00e+00 1011.00
IUUC-Aly-006289 Arabidopsis lyrata 47.96 2.00e-124 439.00
IUUC-Ath-007014 Arabidopsis thaliana 48.07 1.00e-124 440.00
IUUC-Ago-007957 Ashbya gossypii 44.16 4.00e-117 415.00
IUUC-Acl-008103 Aspergillus clavatus 60.93 1.00e-100 360.00
IUUC-Afl-008555 Aspergillus flavus 60.57 5.00e-101 362.00
IUUC-Afu-008949 Aspergillus fumigatus 60.93 8.00e-101 361.00
IUUC-Ani-009408 Aspergillus nidulans 63.06 3.00e-101 362.00
IUUC-Ang-009551 Aspergillus niger 60.93 2.00e-100 360.00
IUUC-Aor-010176 Aspergillus oryzae 60.57 4.00e-101 362.00
IUUC-Ate-010287 Aspergillus terreus 60.93 2.00e-100 360.00
IUUC-Ame-011019 Astyanax mexicanus 88.26 0.00e+00 1012.00
IUUC-Bgr-012045 Blumeria graminis 62.31 2.00e-101 362.00
IUUC-Bta-012786 Bos taurus 74.01 0.00e+00 792.00
IUUC-Bci-013774 Botrytis cinerea 48.29 2.00e-103 369.00
IUUC-Bdi-014319 Brachypodium distachyon 47.46 4.00e-122 431.00
IUUC-Bol-016242 Brassica oleracea 48.25 3.00e-128 451.00
IUUC-Bra-016750 Brassica rapa 48.35 2.00e-128 452.00
IUUC-Cel-018518 Caenorhabditis elegans 57.83 0.00e+00 630.00
IUUC-Cja-019386 Callithrix jacchus 92.04 0.00e+00 1054.00
IUUC-Cfa-020177 Canis familiaris 73.58 0.00e+00 764.00
IUUC-Cpo-021805 Cavia porcellus 92.22 0.00e+00 1054.00
IUUC-Cre-022915 Chlamydomonas reinhardtii 54.97 2.00e-95 341.00
IUUC-Csa-024267 Chlorocebus sabaeus 92.22 0.00e+00 1048.00
IUUC-Cho-024859 Choloepus hoffmanni 71.88 0.00e+00 751.00
IUUC-Cin-025550 Ciona intestinalis 62.09 0.00e+00 670.00
IUUC-Csv-026139 Ciona savignyi 61.06 0.00e+00 679.00
IUUC-Cne-027044 Cryptococcus neoformans 51.66 7.00e-108 384.00
IUUC-Cme-027289 Cyanidioschyzon merolae 46.50 8.00e-112 397.00
IUUC-Dre-027749 Danio rerio 71.70 0.00e+00 791.00
IUUC-Dno-030006 Dasypus novemcinctus 74.01 0.00e+00 791.00
IUUC-Dor-030578 Dipodomys ordii 91.68 0.00e+00 1052.00
IUUC-Dse-031507 Dothistroma septosporum 63.20 8.00e-104 371.00
IUUC-Dme-031704 Drosophila melanogaster 60.27 0.00e+00 657.00
IUUC-Ete-033055 Echinops telfairi 72.11 0.00e+00 808.00
IUUC-Eca-034016 Equus caballus 93.09 0.00e+00 996.00
IUUC-Fca-035754 Felis catus 72.20 0.00e+00 783.00
IUUC-Fal-037363 Ficedula albicollis 73.56 0.00e+00 781.00
IUUC-Fox-038073 Fusarium oxysporum 42.75 4.00e-104 372.00
IUUC-Fso-038236 Fusarium solani 51.37 8.00e-101 361.00
IUUC-Gmo-039633 Gadus morhua 70.78 0.00e+00 815.00
IUUC-Ggr-039987 Gaeumannomyces graminis 48.91 9.00e-101 360.00
IUUC-Gga-040546 Gallus gallus 92.78 0.00e+00 1046.00
IUUC-Gac-041822 Gasterosteus aculeatus 86.51 0.00e+00 958.00
IUUC-Gma-042712 Glycine max 46.95 4.00e-124 438.00
IUUC-Ggo-045303 Gorilla gorilla 92.41 0.00e+00 1060.00
IUUC-Hsa-045746 Homo sapiens 92.41 0.00e+00 1060.00
IUUC-Hvu-047406 Hordeum vulgare 47.68 2.00e-123 435.00
IUUC-Itr-048134 Ictidomys tridecemlineatus 92.41 0.00e+00 1059.00
IUUC-Kpa-049190 Komagataella pastoris 45.40 1.00e-122 433.00
IUUC-Lch-049623 Latimeria chalumnae 73.04 0.00e+00 781.00
IUUC-Lpe-051392 Leersia perrieri 47.25 7.00e-124 437.00
IUUC-Loc-052928 Lepisosteus oculatus 92.06 0.00e+00 1033.00
IUUC-Lma-053054 Leptosphaeria maculans 63.43 3.00e-105 375.00
IUUC-Laf-053459 Loxodonta africana 92.59 0.00e+00 1062.00
IUUC-Mcc-055862 Macaca mulatta 92.41 0.00e+00 1060.00
IUUC-Mor-057170 Magnaporthe oryzae 49.57 1.00e-98 354.00
IUUC-Mpo-057302 Magnaporthe poae 49.04 8.00e-101 361.00
IUUC-Mtr-058309 Medicago truncatula 48.43 8.00e-125 440.00
IUUC-Mla-059058 Melampsora laricipopulina 43.78 1.00e-104 373.00
IUUC-Mga-059206 Meleagris gallopavo 92.71 0.00e+00 991.00
IUUC-Mvi-060337 Microbotryum violaceum 42.61 4.00e-108 385.00
IUUC-Mmr-061619 Microcebus murinus 92.22 0.00e+00 1048.00
IUUC-Mdo-062160 Monodelphis domestica 92.39 0.00e+00 1047.00
IUUC-Mmu-063406 Mus musculus 90.96 0.00e+00 1040.00
IUUC-Mac-064518 Musa acuminata 45.65 2.00e-120 426.00
IUUC-Mpu-066326 Mustela putorius furo 92.51 0.00e+00 999.00
IUUC-Mlu-067968 Myotis lucifugus 92.35 0.00e+00 968.00
IUUC-Nfi-068493 Neosartorya fischeri 60.93 7.00e-101 361.00
IUUC-Ncr-068665 Neurospora crassa 62.69 5.00e-104 372.00
IUUC-Nle-070158 Nomascus leucogenys 92.41 0.00e+00 1060.00
IUUC-Opr-070272 Ochotona princeps 72.58 0.00e+00 779.00
IUUC-Ont-071395 Oreochromis niloticus 88.37 0.00e+00 996.00
IUUC-Oan-073322 Ornithorhynchus anatinus 68.83 0.00e+00 745.00
IUUC-Ocu-074188 Oryctolagus cuniculus 72.76 0.00e+00 782.00
IUUC-Oba-075436 Oryza barthii 47.14 1.00e-124 439.00
IUUC-Obr-076507 Oryza brachyantha 47.68 5.00e-125 441.00
IUUC-Ogl-077718 Oryza glaberrima 47.39 3.00e-123 435.00
IUUC-Ogu-078349 Oryza glumaepatula 46.81 1.00e-124 439.00
IUUC-Oin-079889 Oryza indica 46.72 3.00e-124 438.00
IUUC-Olo-080521 Oryza longistaminata 47.14 1.00e-124 439.00
IUUC-Ome-081630 Oryza meridionalis 46.94 3.00e-124 438.00
IUUC-Oni-082211 Oryza nivara 47.14 8.00e-125 440.00
IUUC-Opu-083617 Oryza punctata 46.71 8.00e-124 437.00
IUUC-Oru-084252 Oryza rufipogon 47.14 1.00e-124 439.00
IUUC-Osa-085548 Oryza sativa 47.14 1.00e-124 439.00
IUUC-Ola-087169 Oryzias latipes 86.40 0.00e+00 974.00
IUUC-Olu-087861 Ostreococcus lucimarinus 43.81 2.00e-116 412.00
IUUC-Oga-088003 Otolemur garnettii 74.19 0.00e+00 792.00
IUUC-Oar-089933 Ovis aries 74.01 0.00e+00 792.00
IUUC-Ptr-090741 Pan troglodytes 92.41 0.00e+00 1060.00
IUUC-Pan-092526 Papio anubis 74.37 0.00e+00 792.00
IUUC-Psi-094034 Pelodiscus sinensis 73.33 0.00e+00 777.00
IUUC-Pno-095030 Phaeosphaeria nodorum 63.43 1.00e-103 369.00
IUUC-Ppa-095615 Physcomitrella patens 49.78 3.00e-121 428.00
IUUC-Pfo-096295 Poecilia formosa 86.76 0.00e+00 987.00
IUUC-Pab-098023 Pongo abelii 92.41 0.00e+00 1060.00
IUUC-Pop-100042 Populus trichocarpa 47.68 1.00e-126 446.00
IUUC-Pca-101104 Procavia capensis 77.94 4.00e-172 597.00
IUUC-Ppe-101642 Prunus persica 48.85 2.00e-124 439.00
IUUC-Pva-102470 Pteropus vampyrus 91.86 0.00e+00 1046.00
IUUC-Pgr-103406 Puccinia graminis 61.89 9.00e-91 327.00
IUUC-Ptt-103713 Puccinia triticina 37.80 7.00e-79 288.00
IUUC-Pte-104259 Pyrenophora teres 63.43 6.00e-105 375.00
IUUC-Pyt-104752 Pyrenophora triticirepentis 63.81 2.00e-105 377.00
IUUC-Rno-104960 Rattus norvegicus 92.22 0.00e+00 1058.00
IUUC-Sce-106290 Saccharomyces cerevisiae 43.30 2.00e-117 416.00
IUUC-Sha-107603 Sarcophilus harrisii 73.84 0.00e+00 788.00
IUUC-Sja-107772 Schizosaccharomyces japonicus 42.12 1.00e-111 396.00
IUUC-Spo-108202 Schizosaccharomyces pombe 41.65 2.00e-108 385.00
IUUC-Ssl-108535 Sclerotinia sclerotiorum 47.84 6.00e-103 368.00
IUUC-Smo-109309 Selaginella moellendorffii 45.74 1.00e-120 426.00
IUUC-Sit-109745 Setaria italica 47.88 6.00e-125 441.00
IUUC-Sly-110890 Solanum lycopersicum 48.19 2.00e-125 442.00
IUUC-Stu-112144 Solanum tuberosum 46.14 2.00e-117 416.00
IUUC-Sar-113521 Sorex araneus 64.94 0.00e+00 636.00
IUUC-Sbi-114764 Sorghum bicolor 47.90 2.00e-126 445.00
IUUC-Sre-115141 Sporisorium reilianum 67.77 2.00e-114 406.00
IUUC-Ssc-115732 Sus scrofa 74.00 0.00e+00 761.00
IUUC-Tgu-117190 Taeniopygia guttata 73.56 0.00e+00 778.00
IUUC-Tru-118735 Takifugu rubripes 86.76 0.00e+00 984.00
IUUC-Tsy-119503 Tarsius syrichta 89.23 0.00e+00 947.00
IUUC-Tni-119880 Tetraodon nigroviridis 86.56 0.00e+00 997.00
IUUC-Tca-121386 Theobroma cacao 47.77 4.00e-126 444.00
IUUC-Tre-122070 Trichoderma reesei 51.22 2.00e-103 369.00
IUUC-Tvi-122305 Trichoderma virens 48.59 3.00e-102 365.00
IUUC-Tae-123515 Triticum aestivum 47.03 2.00e-124 438.00
IUUC-Tur-126416 Triticum urartu 47.87 2.00e-122 432.00
IUUC-Tme-127174 Tuber melanosporum 54.05 2.00e-67 249.00
IUUC-Tbe-127791 Tupaia belangeri 84.78 1.00e-111 396.00
IUUC-Ttr-129224 Tursiops truncatus 72.38 0.00e+00 781.00
IUUC-Uma-129372 Ustilago maydis 67.77 1.00e-113 404.00
IUUC-Vda-129819 Verticillium dahliae 53.85 5.00e-85 308.00
IUUC-Vpa-130220 Vicugna pacos 92.31 0.00e+00 996.00
IUUC-Vvi-131649 Vitis vinifera 48.28 6.00e-125 441.00
IUUC-Xma-134119 Xiphophorus maculatus 86.76 0.00e+00 986.00
IUUC-Yli-134422 Yarrowia lipolytica 45.44 2.00e-118 419.00
IUUC-Zma-135621 Zea mays 62.11 8.00e-119 421.00
Created Date 25-Jun-2017

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