iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098711

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01089905

Gene Name

KLHL41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000012912.2	ENSPPYT00000014997.2	ENSPPYP00000014411.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-17	63.4	34	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.10e-10	39.7	132	162

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           D++l+ g++  ++h+++L+a+S++F+  fl+e +e k k++v+++ v+p  +  ++k+lY+ ++d+n+
   Q: 34   DCTLKAGDKSLPCHRLILSACSPYFREYFLSEIDEAK-KKEVVLDNVDPAILDLIIKYLYSASIDLND 100
           9***********************************9.***************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Ncl+ilr++ l+dcp+L+ +a++f+++ F
   Q: 132  PGNCLAILRLGLLLDCPRLAISAREFVSDRF 162
           56***************************99 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDSQRELAEE LRLYQSTLLQ DGLKDLLDEK KFIDCTLKAG DKSLPCHRLI LSACSPYFRE 60
YFLSEIDEAK KKEVVLDNVD PAILDLIIKY LYSASIDLND GNVQDIFALA SRFQIPSVFT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAACAACTCT TCTTTCCAAG CCAGCTCTCC TAAATTCCCG TTGTTAGAGT TGGTATCTAT 60
ATTTAGCTAG TGGGATTAAG TTGCAAAGGC TTCAAGCTGG GCAAAGCACA CTGATCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030571--KLHL41
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005856--C:cytoskeleton
GO:0005829--C:cytosol
GO:0031430--C:M band
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0033017--C:sarcoplasmic reticulum membrane
GO:0016567--P:protein ubiquitination
GO:0045661--P:regulation of myoblast differentiation
GO:2000291--P:regulation of myoblast proliferation
GO:2001014--P:regulation of skeletal muscle cell differentiation
GO:0045214--P:sarcomere organization
GO:0035914--P:skeletal muscle cell differentiation
GO:0048741--P:skeletal muscle fiber development

KEGG

pon:100457032

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002167	Ailuropoda melanoleuca	96.86	0.00e+00	1181.00
IUUC-Apl-003866	Anas platyrhynchos	85.97	0.00e+00	1040.00
IUUC-Aca-005275	Anolis carolinensis	50.88	0.00e+00	626.00
IUUC-Ame-011172	Astyanax mexicanus	62.02	0.00e+00	753.00
IUUC-Bta-012925	Bos taurus	97.36	0.00e+00	1188.00
IUUC-Bci-013875	Botrytis cinerea	29.58	1.00e-18	87.00
IUUC-Bdi-014115	Brachypodium distachyon	24.68	4.00e-11	62.40
IUUC-Cja-019348	Callithrix jacchus	98.18	0.00e+00	1194.00
IUUC-Cfa-020782	Canis familiaris	97.69	0.00e+00	1188.00
IUUC-Cpo-021825	Cavia porcellus	93.07	0.00e+00	1135.00
IUUC-Csa-023184	Chlorocebus sabaeus	99.04	0.00e+00	1026.00
IUUC-Cin-025237	Ciona intestinalis	29.62	8.00e-71	261.00
IUUC-Dre-028278	Danio rerio	60.26	0.00e+00	774.00
IUUC-Dno-029516	Dasypus novemcinctus	95.38	0.00e+00	1168.00
IUUC-Dor-030850	Dipodomys ordii	92.71	0.00e+00	758.00
IUUC-Ete-032697	Echinops telfairi	94.22	0.00e+00	1133.00
IUUC-Eca-033714	Equus caballus	97.19	0.00e+00	1187.00
IUUC-Eeu-035245	Erinaceus europaeus	94.73	0.00e+00	1069.00
IUUC-Fca-035823	Felis catus	44.18	4.00e-161	561.00
IUUC-Fal-037632	Ficedula albicollis	56.07	0.00e+00	678.00
IUUC-Gmo-039392	Gadus morhua	57.64	0.00e+00	732.00
IUUC-Ggr-040041	Gaeumannomyces graminis	27.78	5.00e-08	52.00
IUUC-Gga-041106	Gallus gallus	85.31	0.00e+00	1054.00
IUUC-Gac-042252	Gasterosteus aculeatus	60.70	0.00e+00	772.00
IUUC-Ggo-044817	Gorilla gorilla	99.67	0.00e+00	1205.00
IUUC-Hsa-046620	Homo sapiens	99.83	0.00e+00	1206.00
IUUC-Lch-050477	Latimeria chalumnae	69.64	0.00e+00	858.00
IUUC-Loc-051955	Lepisosteus oculatus	70.30	0.00e+00	911.00
IUUC-Laf-053500	Loxodonta africana	96.37	0.00e+00	1174.00
IUUC-Mcc-055316	Macaca mulatta	99.17	0.00e+00	1199.00
IUUC-Meu-055972	Macropus eugenii	51.71	0.00e+00	653.00
IUUC-Mor-057181	Magnaporthe oryzae	26.95	1.00e-10	60.80
IUUC-Mga-059451	Meleagris gallopavo	56.86	0.00e+00	707.00
IUUC-Mmr-061444	Microcebus murinus	98.18	0.00e+00	1191.00
IUUC-Mmu-064147	Mus musculus	95.21	0.00e+00	1164.00
IUUC-Mlu-067481	Myotis lucifugus	94.55	0.00e+00	1161.00
IUUC-Ncr-068938	Neurospora crassa	30.10	9.00e-08	52.00
IUUC-Nle-069339	Nomascus leucogenys	99.67	0.00e+00	1205.00
IUUC-Opr-070703	Ochotona princeps	96.20	0.00e+00	1130.00
IUUC-Ont-072420	Oreochromis niloticus	60.86	0.00e+00	793.00
IUUC-Oan-073476	Ornithorhynchus anatinus	92.57	0.00e+00	1135.00
IUUC-Ocu-074248	Oryctolagus cuniculus	96.70	0.00e+00	1185.00
IUUC-Ola-086361	Oryzias latipes	61.67	0.00e+00	780.00
IUUC-Oar-090349	Ovis aries	97.19	0.00e+00	1187.00
IUUC-Pan-092069	Papio anubis	99.34	0.00e+00	1201.00
IUUC-Psi-093671	Pelodiscus sinensis	88.28	0.00e+00	1053.00
IUUC-Pma-094586	Petromyzon marinus	56.43	5.00e-93	333.00
IUUC-Pfo-096122	Poecilia formosa	61.96	0.00e+00	810.00
IUUC-Pca-100495	Procavia capensis	88.45	0.00e+00	1055.00
IUUC-Pva-102401	Pteropus vampyrus	96.86	0.00e+00	1183.00
IUUC-Rno-105969	Rattus norvegicus	95.05	0.00e+00	1161.00
IUUC-Sha-107091	Sarcophilus harrisii	51.52	0.00e+00	675.00
IUUC-Sar-113405	Sorex araneus	92.90	0.00e+00	1124.00
IUUC-Tgu-116725	Taeniopygia guttata	85.64	0.00e+00	1075.00
IUUC-Tru-117743	Takifugu rubripes	59.20	0.00e+00	764.00
IUUC-Tsy-119225	Tarsius syrichta	90.26	0.00e+00	1080.00
IUUC-Tni-120547	Tetraodon nigroviridis	62.13	0.00e+00	791.00
IUUC-Ttr-128645	Tursiops truncatus	96.86	0.00e+00	1181.00
IUUC-Vpa-130714	Vicugna pacos	97.19	0.00e+00	1185.00
IUUC-Xtr-132144	Xenopus tropicalis	76.57	0.00e+00	945.00
IUUC-Xma-133860	Xiphophorus maculatus	62.13	0.00e+00	811.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence