iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tvi-122303

Ensembl Protein ID

EHK24119

UniProt Accession

G9MQQ2; G9MQQ2_HYPVG

Genbank Protein ID

EHK24119.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

ABDF02000005

Gene Name

TRIVIDRAFT_58141

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIVIDRAFT_58141	EHK24119	EHK24119

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.80e-53	179.5	301	779
UBD/Alpha-Helix/UBA	5.60e-21	73.4	584	623

Active Site

Position(s)	Description	Evidence
310	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
734	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk................avsprellkalkkeaeefs 85
           tGlkNlgN+CY+ S++QcL+ +p++re + +   ++l+    +ep ++l ++l+k+ + l++++ +                  +p ++++ +++ +eefs
   Q: 301  TGLKNLGNSCYLASIIQCLFDMPSFRERYYS-ADNDLPII--QEPAADLETQLRKIAHGLLSGRYSepdtsvgsgseiayqrGLAPAMFKHLIGRGHEEFS 398
           7******************************.77777765..79****************84444444566777888888889****************** PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke. 185
           +++qqDa E++++l++ ++++                           +++  ++  +  F++ l+++++cl c++v  + ++   + ++vp ++ +++  
   Q: 399  TMRQQDAFELFQHLFKLISRSP--------------------------HNEADQKDPTAEFRFVLEQRLQCLGCHKVRYSSNEQDNIFIDVPLEKLEETGe 473
           ********************99..........................667777788999*****************966666666667777666443336 PP
   S: 186  ...........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts....... 267
                      +l++cL++ft +e++e    + c++c +k   +k+  +k++P+vL ++  ++     +++++ki+  v +p+e + l+++ ++       
   Q: 474  ggetanaykpvTLKECLDNFTGAEKVE----LTCPSCGSKAGFTKQSLFKTFPNVLAVNARKM--AVVNWVPIKIDVPVIVPDEpFLLDEYISKglqpsee 568
           79999999999***************9....9*******************************..6678*************************8998888 PP
   S: 268  .................................................................................................peek 271
                                                                                                                
   Q: 569  llpdepenkapafvadatavaqleamgfprnraekalhatgnsdanaamewlfahlddtdidapldlgsgsgdagtadpekiemlgamgfgapqakkA--- 666
           88888888888887777777777777777777777777776666666666666666666666666666666666666666666666666666555550... PP
   S: 272  qke..............................................kkkYeLiavvvHsG.slssGHYvayvkn..ekgk.....WllfdDskVtevk 318
                                                            + +++L ++v+H+G s++ GHYva++++  e  +     W+lf+D+kV e  
   Q: 667  --LketggdveravewlfshpddqgitedessgaaaetsskepagsaalPARFQLQSIVCHKGtSIHAGHYVAFIRKslE--GresptWVLFNDEKVVEA- 762
           ..05555555556666666666666666666666777777778888899****************************651..235567*********988. PP
   S: 319  eeevleetgstaYvlfYkr 337
            ++v+e++ + aYv+f+kr
   Q: 763  -HDVEEMR-KFAYVYFFKR 779
           .5666644.79******98 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           d  +++ql++MGF+r++a +aL a+ n +++aA+e+L+ +
   Q: 584  DATAVAQLEAMGFPRNRAEKALHATgNSDANAAMEWLFAH 623
           5679*********************************976 PP

Organism

Trichoderma virens

Protein Sequence
(Fasta)

MSCPHLESIE LKPPTPVQSV YKEDCTQCFD SIDNSGGLDV CLQCFNGGCT GDREHSLLHN 60
AVWGHPLALN IRRTRKTIHR DEPPAKMTKL AIAAETEEDR YDTALAAKCI ECQIELDISN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGTGCC CGCATCTCGA GTCTATCGGT ACGTCAAATC CTTACCCCGC CAGCTTGAGC 60
TTCGCAGCTC TTCCAGCTGC CGTGAAGCTC AAGAAGGCTC ATGTTTCGTC GTCATAGAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000394	Aegilops tauschii	33.80	6.00e-98	350.00
IUUC-Aml-002104	Ailuropoda melanoleuca	34.76	8.00e-131	459.00
IUUC-Atr-002580	Amborella trichopoda	34.91	4.00e-117	414.00
IUUC-Apl-003774	Anas platyrhynchos	35.26	1.00e-126	445.00
IUUC-Aca-005368	Anolis carolinensis	35.36	1.00e-134	471.00
IUUC-Aly-005727	Arabidopsis lyrata	37.55	4.00e-127	447.00
IUUC-Ath-006974	Arabidopsis thaliana	37.82	3.00e-127	447.00
IUUC-Ago-007890	Ashbya gossypii	32.44	7.00e-114	403.00
IUUC-Acl-008057	Aspergillus clavatus	56.14	0.00e+00	888.00
IUUC-Afl-008547	Aspergillus flavus	57.40	0.00e+00	786.00
IUUC-Afu-008805	Aspergillus fumigatus	53.49	0.00e+00	794.00
IUUC-Ani-009441	Aspergillus nidulans	51.51	0.00e+00	695.00
IUUC-Ang-009720	Aspergillus niger	57.32	0.00e+00	909.00
IUUC-Aor-010111	Aspergillus oryzae	57.74	0.00e+00	943.00
IUUC-Ate-010531	Aspergillus terreus	54.31	0.00e+00	841.00
IUUC-Ame-011893	Astyanax mexicanus	34.78	1.00e-105	375.00
IUUC-Bgr-012183	Blumeria graminis	60.96	0.00e+00	987.00
IUUC-Bta-013179	Bos taurus	34.76	7.00e-130	456.00
IUUC-Bci-013858	Botrytis cinerea	66.71	0.00e+00	1124.00
IUUC-Bdi-014904	Brachypodium distachyon	35.42	1.00e-105	375.00
IUUC-Bol-015536	Brassica oleracea	36.68	1.00e-126	445.00
IUUC-Bra-017939	Brassica rapa	37.02	9.00e-129	452.00
IUUC-Cel-018625	Caenorhabditis elegans	31.19	2.00e-86	311.00
IUUC-Cja-019063	Callithrix jacchus	34.38	9.00e-128	449.00
IUUC-Cfa-020976	Canis familiaris	35.75	8.00e-134	469.00
IUUC-Cpo-022265	Cavia porcellus	35.71	5.00e-134	470.00
IUUC-Cre-022640	Chlamydomonas reinhardtii	33.69	1.00e-68	252.00
IUUC-Csa-024177	Chlorocebus sabaeus	35.76	9.00e-120	422.00
IUUC-Cho-024702	Choloepus hoffmanni	32.70	1.00e-78	286.00
IUUC-Cin-025411	Ciona intestinalis	32.85	3.00e-99	354.00
IUUC-Csv-026347	Ciona savignyi	30.79	1.00e-96	345.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	73.22	0.00e+00	1127.00
IUUC-Cne-026831	Cryptococcus neoformans	46.78	0.00e+00	642.00
IUUC-Cme-027335	Cyanidioschyzon merolae	33.10	2.00e-56	212.00
IUUC-Dre-027982	Danio rerio	31.89	8.00e-102	363.00
IUUC-Dno-029034	Dasypus novemcinctus	34.99	6.00e-132	463.00
IUUC-Dor-030479	Dipodomys ordii	35.97	2.00e-60	226.00
IUUC-Dse-031467	Dothistroma septosporum	55.92	0.00e+00	880.00
IUUC-Dme-032075	Drosophila melanogaster	33.54	3.00e-112	397.00
IUUC-Ete-032865	Echinops telfairi	31.79	4.00e-108	384.00
IUUC-Eca-034059	Equus caballus	34.76	3.00e-129	454.00
IUUC-Eeu-035304	Erinaceus europaeus	35.50	1.00e-119	422.00
IUUC-Fca-035515	Felis catus	34.76	2.00e-130	458.00
IUUC-Fal-037271	Ficedula albicollis	35.87	9.00e-125	439.00
IUUC-Fox-037745	Fusarium oxysporum	80.10	0.00e+00	1274.00
IUUC-Fso-038158	Fusarium solani	80.38	0.00e+00	1276.00
IUUC-Gmo-039071	Gadus morhua	32.86	4.00e-111	394.00
IUUC-Ggr-040098	Gaeumannomyces graminis	69.94	0.00e+00	1068.00
IUUC-Gga-040635	Gallus gallus	34.89	6.00e-131	459.00
IUUC-Gac-042528	Gasterosteus aculeatus	33.96	1.00e-110	392.00
IUUC-Gma-043614	Glycine max	35.01	9.00e-116	409.00
IUUC-Ggo-044602	Gorilla gorilla	34.88	1.00e-130	459.00
IUUC-Hsa-045959	Homo sapiens	34.88	1.00e-130	459.00
IUUC-Hvu-047563	Hordeum vulgare	37.74	4.00e-101	360.00
IUUC-Itr-048712	Ictidomys tridecemlineatus	35.19	6.00e-132	463.00
IUUC-Kpa-049156	Komagataella pastoris	41.92	3.00e-175	607.00
IUUC-Lch-049648	Latimeria chalumnae	35.76	5.00e-124	437.00
IUUC-Lpe-051523	Leersia perrieri	34.10	4.00e-108	384.00
IUUC-Loc-052072	Lepisosteus oculatus	32.63	7.00e-111	393.00
IUUC-Lma-053216	Leptosphaeria maculans	64.13	0.00e+00	969.00
IUUC-Laf-054327	Loxodonta africana	35.08	1.00e-130	459.00
IUUC-Mcc-055443	Macaca mulatta	34.88	1.00e-130	458.00
IUUC-Meu-056298	Macropus eugenii	34.54	7.00e-87	313.00
IUUC-Mor-057106	Magnaporthe oryzae	71.52	0.00e+00	1134.00
IUUC-Mpo-057589	Magnaporthe poae	70.73	0.00e+00	1077.00
IUUC-Mtr-058680	Medicago truncatula	35.90	1.00e-120	425.00
IUUC-Mla-058903	Melampsora laricipopulina	43.70	9.00e-177	612.00
IUUC-Mga-059669	Meleagris gallopavo	34.68	9.00e-124	436.00
IUUC-Mvi-060476	Microbotryum violaceum	43.27	7.00e-179	619.00
IUUC-Mmr-060575	Microcebus murinus	34.99	5.00e-131	460.00
IUUC-Mdo-062183	Monodelphis domestica	34.91	5.00e-129	453.00
IUUC-Mmu-063592	Mus musculus	34.99	4.00e-131	460.00
IUUC-Mac-065634	Musa acuminata	36.71	3.00e-66	245.00
IUUC-Mpu-066082	Mustela putorius furo	35.99	1.00e-133	469.00
IUUC-Mlu-067345	Myotis lucifugus	34.61	1.00e-129	455.00
IUUC-Nfi-068558	Neosartorya fischeri	56.73	0.00e+00	862.00
IUUC-Ncr-068960	Neurospora crassa	70.71	0.00e+00	1063.00
IUUC-Nle-070173	Nomascus leucogenys	35.75	3.00e-133	467.00
IUUC-Opr-070556	Ochotona princeps	35.19	9.00e-131	459.00
IUUC-Ont-071502	Oreochromis niloticus	33.97	1.00e-114	405.00
IUUC-Oan-072959	Ornithorhynchus anatinus	40.53	7.00e-46	175.00
IUUC-Ocu-074861	Oryctolagus cuniculus	36.19	2.00e-133	468.00
IUUC-Oba-075109	Oryza barthii	34.56	2.00e-111	395.00
IUUC-Obr-076292	Oryza brachyantha	34.68	2.00e-106	378.00
IUUC-Ogl-077065	Oryza glaberrima	35.01	6.00e-118	416.00
IUUC-Ogu-078776	Oryza glumaepatula	34.98	3.00e-114	404.00
IUUC-Oin-080048	Oryza indica	35.13	9.00e-117	412.00
IUUC-Olo-080711	Oryza longistaminata	34.70	3.00e-103	367.00
IUUC-Ome-081506	Oryza meridionalis	35.03	3.00e-104	371.00
IUUC-Oni-082320	Oryza nivara	33.97	7.00e-110	389.00
IUUC-Opu-083801	Oryza punctata	35.01	3.00e-105	374.00
IUUC-Oru-085139	Oryza rufipogon	33.53	1.00e-109	389.00
IUUC-Osa-085713	Oryza sativa	35.13	7.00e-119	419.00
IUUC-Ola-086951	Oryzias latipes	32.36	1.00e-105	375.00
IUUC-Olu-087822	Ostreococcus lucimarinus	32.24	6.00e-100	357.00
IUUC-Oga-088625	Otolemur garnettii	34.76	7.00e-131	459.00
IUUC-Oar-089995	Ovis aries	34.53	1.00e-129	456.00
IUUC-Ptr-090640	Pan troglodytes	35.34	5.00e-133	466.00
IUUC-Pan-091974	Papio anubis	34.72	1.00e-130	459.00
IUUC-Psi-093957	Pelodiscus sinensis	35.04	8.00e-134	469.00
IUUC-Pma-094242	Petromyzon marinus	38.76	6.00e-70	256.00
IUUC-Pno-094835	Phaeosphaeria nodorum	62.77	0.00e+00	880.00
IUUC-Ppa-095901	Physcomitrella patens	36.81	3.00e-128	451.00
IUUC-Pfo-097148	Poecilia formosa	34.29	4.00e-115	407.00
IUUC-Pab-098068	Pongo abelii	32.52	2.00e-110	392.00
IUUC-Pop-098943	Populus trichocarpa	35.06	2.00e-116	411.00
IUUC-Pca-100738	Procavia capensis	35.93	6.00e-96	343.00
IUUC-Ppe-101315	Prunus persica	34.51	2.00e-116	411.00
IUUC-Pva-102154	Pteropus vampyrus	34.18	7.00e-128	449.00
IUUC-Pgr-103343	Puccinia graminis	43.45	8.00e-151	525.00
IUUC-Ptt-103928	Puccinia triticina	38.12	3.00e-147	513.00
IUUC-Pte-104306	Pyrenophora teres	64.56	0.00e+00	936.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	62.80	0.00e+00	946.00
IUUC-Rno-105801	Rattus norvegicus	35.23	7.00e-132	463.00
IUUC-Sce-106304	Saccharomyces cerevisiae	33.90	7.00e-117	413.00
IUUC-Sha-107635	Sarcophilus harrisii	34.84	7.00e-131	459.00
IUUC-Sja-107678	Schizosaccharomyces japonicus	44.08	3.00e-178	616.00
IUUC-Spo-108144	Schizosaccharomyces pombe	42.73	8.00e-178	615.00
IUUC-Smo-108848	Selaginella moellendorffii	38.18	1.00e-121	429.00
IUUC-Sit-110728	Setaria italica	35.91	2.00e-120	424.00
IUUC-Sly-111523	Solanum lycopersicum	37.16	7.00e-129	452.00
IUUC-Sar-113733	Sorex araneus	34.55	8.00e-58	217.00
IUUC-Sbi-114419	Sorghum bicolor	35.29	1.00e-114	405.00
IUUC-Sre-115225	Sporisorium reilianum	44.76	0.00e+00	635.00
IUUC-Ssc-115686	Sus scrofa	34.84	2.00e-130	458.00
IUUC-Tgu-117346	Taeniopygia guttata	34.31	5.00e-127	446.00
IUUC-Tru-118350	Takifugu rubripes	32.75	3.00e-110	390.00
IUUC-Tsy-119278	Tarsius syrichta	31.75	3.00e-87	314.00
IUUC-Tni-120658	Tetraodon nigroviridis	32.75	7.00e-105	373.00
IUUC-Tca-121585	Theobroma cacao	34.57	4.00e-116	410.00
IUUC-Tre-122043	Trichoderma reesei	90.90	0.00e+00	1420.00
IUUC-Tae-123798	Triticum aestivum	34.77	3.00e-112	397.00
IUUC-Tur-126732	Triticum urartu	33.46	2.00e-102	365.00
IUUC-Tme-126909	Tuber melanosporum	60.95	0.00e+00	927.00
IUUC-Tbe-127261	Tupaia belangeri	31.54	4.00e-76	278.00
IUUC-Ttr-129119	Tursiops truncatus	36.76	8.00e-60	223.00
IUUC-Uma-129599	Ustilago maydis	44.71	0.00e+00	664.00
IUUC-Vda-129688	Verticillium dahliae	73.98	0.00e+00	1137.00
IUUC-Vpa-130170	Vicugna pacos	29.51	9.00e-74	270.00
IUUC-Vvi-131116	Vitis vinifera	34.67	3.00e-112	397.00
IUUC-Xtr-131953	Xenopus tropicalis	33.53	6.00e-110	390.00
IUUC-Xma-133837	Xiphophorus maculatus	34.17	1.00e-114	405.00
IUUC-Yli-134510	Yarrowia lipolytica	44.85	4.00e-177	613.00
IUUC-Zma-135786	Zea mays	35.82	7.00e-109	386.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence