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Tag Content
UUCD2 ID IUUC-Ptr-091039
UUCD1 version UUC-PaT-00603
Ensembl Protein ID ENSPTRP00000029931.3
UniProt Accession H2QS02; H2QS02_PANTR
Genbank Protein ID ENSPTRP00000029931
Protein Name Uncharacterized protein
Genbank Nucleotide ID AACZ03038602
Gene Name FBXW11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPTRG00000017526.5 ENSPTRT00000032395.3 ENSPTRP00000029931.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.20e-57 187.5 441 475
UBD/Beta-Prp 2.00e-69 234.0 354 519
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ v+c++f d +++vsG++Dg+ikvWDl    +
   Q: 441  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLQAALD 475
           8**********.44****************977665 PP
   

   UBD/Beta-Prp
   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee 131
           +l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ 
   Q: 354  TLRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWSTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR- 437
           4556679*************9..8**************************************..************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.........ktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdl 209
           +l+gh+++v+c++++   + +vsG++D+++++Wdl         ++  +lrtl + h ++v  l+fd+  ++++s s+d t+ +wd+
   Q: 438  VLEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLqaaldprapASTLCLRTLVE-HSGRVFRLQFDE--FQIISSSHDDTILIWDF 519
           ***************9..***********************************99.************..99**************7 PP
   
Organism Pan troglodytes
Protein Sequence
(Fasta)
MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQI SNGTSSVIVS 60
RKRPSEGNYQ KEKDLCIKYF DQWSESDQVE FVEHLISRMC HYQHGHINSY LKPMLQRDFI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ptr-091039|E3,WD_repeat;UBD,Beta-Prp|Pan troglodytes
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAGTCGTGG CGCTCTCGAG GCCCTACCAT GAGCAAGCTC TTAACTCTTC AGGTCTGCAC 60
GTCCTACGTC CACAGTCCAG TGCTACTCTC AGCTCGGAGT TCAGCTTCGG GCTGCCAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ptr-091039|E3,WD_repeat;UBD,Beta-Prp|Pan troglodytes
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40
Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0042347--P:negative regulation of NF-kappaB import into nucleus
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001397 Ailuropoda melanoleuca 99.82 0.00e+00 1118.00
IUUC-Apl-003449 Anas platyrhynchos 94.58 0.00e+00 1067.00
IUUC-Ame-011174 Astyanax mexicanus 83.92 0.00e+00 984.00
IUUC-Bta-012920 Bos taurus 99.80 0.00e+00 1021.00
IUUC-Bci-013685 Botrytis cinerea 30.72 5.00e-54 205.00
IUUC-Cel-018392 Caenorhabditis elegans 63.16 0.00e+00 634.00
IUUC-Cja-018879 Callithrix jacchus 99.82 0.00e+00 1118.00
IUUC-Cfa-020021 Canis familiaris 99.82 0.00e+00 1118.00
IUUC-Cpo-022151 Cavia porcellus 99.39 0.00e+00 1013.00
IUUC-Csa-024095 Chlorocebus sabaeus 99.80 0.00e+00 1020.00
IUUC-Cho-024658 Choloepus hoffmanni 99.62 9.00e-156 543.00
IUUC-Cin-025188 Ciona intestinalis 80.42 0.00e+00 824.00
IUUC-Csv-026020 Ciona savignyi 78.75 0.00e+00 781.00
IUUC-Dre-028160 Danio rerio 92.34 0.00e+00 953.00
IUUC-Dno-029485 Dasypus novemcinctus 88.96 0.00e+00 890.00
IUUC-Dor-030498 Dipodomys ordii 99.24 0.00e+00 1081.00
IUUC-Dme-031885 Drosophila melanogaster 80.63 0.00e+00 810.00
IUUC-Ete-032978 Echinops telfairi 70.43 0.00e+00 735.00
IUUC-Eca-033804 Equus caballus 99.80 0.00e+00 1035.00
IUUC-Fca-035887 Felis catus 94.11 0.00e+00 1037.00
IUUC-Fal-036783 Ficedula albicollis 95.29 0.00e+00 1036.00
IUUC-Fox-037978 Fusarium oxysporum 33.56 2.00e-60 227.00
IUUC-Fso-038077 Fusarium solani 32.52 1.00e-55 211.00
IUUC-Gmo-038590 Gadus morhua 88.03 0.00e+00 975.00
IUUC-Gga-040628 Gallus gallus 94.92 0.00e+00 1031.00
IUUC-Gac-041305 Gasterosteus aculeatus 88.58 0.00e+00 992.00
IUUC-Ggo-044604 Gorilla gorilla 99.82 0.00e+00 1118.00
IUUC-Hsa-046139 Homo sapiens 99.82 0.00e+00 1118.00
IUUC-Itr-047872 Ictidomys tridecemlineatus 88.49 0.00e+00 827.00
IUUC-Lch-050460 Latimeria chalumnae 97.37 0.00e+00 997.00
IUUC-Loc-052686 Lepisosteus oculatus 88.51 0.00e+00 925.00
IUUC-Laf-053968 Loxodonta africana 96.09 0.00e+00 1107.00
IUUC-Mcc-055822 Macaca mulatta 91.40 0.00e+00 1061.00
IUUC-Meu-056078 Macropus eugenii 79.10 0.00e+00 764.00
IUUC-Mga-059225 Meleagris gallopavo 98.79 0.00e+00 1006.00
IUUC-Mvi-060284 Microbotryum violaceum 44.95 1.00e-69 258.00
IUUC-Mmr-060746 Microcebus murinus 99.82 0.00e+00 1118.00
IUUC-Mdo-062005 Monodelphis domestica 99.19 0.00e+00 1015.00
IUUC-Mmu-063851 Mus musculus 96.09 0.00e+00 1107.00
IUUC-Mpu-065716 Mustela putorius furo 99.80 0.00e+00 1021.00
IUUC-Mlu-067001 Myotis lucifugus 99.80 0.00e+00 1020.00
IUUC-Nle-069788 Nomascus leucogenys 93.54 0.00e+00 1031.00
IUUC-Opr-071229 Ochotona princeps 99.63 0.00e+00 1117.00
IUUC-Ont-071792 Oreochromis niloticus 89.57 0.00e+00 998.00
IUUC-Oan-072782 Ornithorhynchus anatinus 95.29 0.00e+00 1036.00
IUUC-Ocu-074894 Oryctolagus cuniculus 96.09 0.00e+00 1107.00
IUUC-Ola-086985 Oryzias latipes 85.87 0.00e+00 998.00
IUUC-Oga-088604 Otolemur garnettii 99.60 0.00e+00 1018.00
IUUC-Oar-090412 Ovis aries 95.86 0.00e+00 1041.00
IUUC-Pan-092770 Papio anubis 95.93 0.00e+00 1059.00
IUUC-Psi-093887 Pelodiscus sinensis 94.01 0.00e+00 1061.00
IUUC-Pma-094315 Petromyzon marinus 83.23 0.00e+00 845.00
IUUC-Pno-094808 Phaeosphaeria nodorum 29.50 2.00e-45 177.00
IUUC-Pfo-096783 Poecilia formosa 86.22 0.00e+00 1003.00
IUUC-Pva-102547 Pteropus vampyrus 99.63 0.00e+00 1104.00
IUUC-Ptt-103853 Puccinia triticina 32.75 2.00e-60 226.00
IUUC-Rno-105246 Rattus norvegicus 95.86 0.00e+00 1042.00
IUUC-Sha-107339 Sarcophilus harrisii 99.19 0.00e+00 1015.00
IUUC-Sja-107743 Schizosaccharomyces japonicus 35.38 3.00e-74 272.00
IUUC-Spo-108200 Schizosaccharomyces pombe 31.92 2.00e-66 246.00
IUUC-Ssc-115490 Sus scrofa 87.90 0.00e+00 918.00
IUUC-Tgu-116541 Taeniopygia guttata 94.57 0.00e+00 1068.00
IUUC-Tru-117671 Takifugu rubripes 85.16 0.00e+00 989.00
IUUC-Tsy-118983 Tarsius syrichta 81.10 0.00e+00 876.00
IUUC-Tni-120359 Tetraodon nigroviridis 85.79 0.00e+00 939.00
IUUC-Tbe-127418 Tupaia belangeri 93.55 0.00e+00 1004.00
IUUC-Ttr-129131 Tursiops truncatus 99.82 0.00e+00 1117.00
IUUC-Vpa-130668 Vicugna pacos 99.44 0.00e+00 1106.00
IUUC-Xtr-132861 Xenopus tropicalis 76.90 0.00e+00 929.00
IUUC-Xma-133187 Xiphophorus maculatus 95.36 8.00e-158 548.00
Created Date 25-Jun-2017

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