iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d041105	Zm00001d041105_T011	Zm00001d041105_T011
Zm00001d041105	Zm00001d041105_T042	Zm00001d041105_T042
Zm00001d041105	Zm00001d041105_T041	Zm00001d041105_T041
Zm00001d041105	Zm00001d041105_T039	Zm00001d041105_T039
Zm00001d041105	Zm00001d041105_T054	Zm00001d041105_T054
Zm00001d041105	Zm00001d041105_T003	Zm00001d041105_T003
Zm00001d041105	Zm00001d041105_T016	Zm00001d041105_T016
Zm00001d041105	Zm00001d041105_T017	Zm00001d041105_T017
Zm00001d041105	Zm00001d041105_T024	Zm00001d041105_T024
Zm00001d041105	Zm00001d041105_T048	Zm00001d041105_T048
Zm00001d041105	Zm00001d041105_T022	Zm00001d041105_T022
Zm00001d041105	Zm00001d041105_T032	Zm00001d041105_T032
Zm00001d041105	Zm00001d041105_T002	Zm00001d041105_T002
Zm00001d041105	Zm00001d041105_T065	Zm00001d041105_T065
Zm00001d041105	Zm00001d041105_T019	Zm00001d041105_T019
Zm00001d041105	Zm00001d041105_T051	Zm00001d041105_T051
Zm00001d041105	Zm00001d041105_T028	Zm00001d041105_T028
Zm00001d041105	Zm00001d041105_T027	Zm00001d041105_T027
Zm00001d041105	Zm00001d041105_T031	Zm00001d041105_T031
Zm00001d041105	Zm00001d041105_T008	Zm00001d041105_T008
Zm00001d041105	Zm00001d041105_T005	Zm00001d041105_T005
Zm00001d041105	Zm00001d041105_T015	Zm00001d041105_T015

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.80e-111	372.5	3417	3598
UBD/Alpha-Helix/UBA	2.00e-07	32.9	1294	1333

Active Site

Position(s)	Description	Evidence
3566	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 159  gGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspai 246
           +G+ni+Vt+eNk++Yv++v+e+rl++ i+ q++af eGfne+ip el+s+F+ +elelli+G ++id++dlk++t+y +gy+  sp+i
   Q: 3417 RGRNIRVTEENKHQYVDRVAEHRLTTAIRPQINAFLEGFNELIPRELISIFNDKELELLISGLPDIDLDDLKANTEY-SGYSIASPVI 3503
           79***************************************************************************.55******** PP
   S: 247  qwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAiee 329
           qwFwe++++fs+e++++fLqFvTg+s++Pl+Gf +l+    p++f+i+k ++s+++lPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e
   Q: 3504 QWFWEIVQGFSKEDKARFLQFVTGTSKVPLEGFSALQgisgPQRFQIHKaYGSTNHLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHE 3591
           *************************************************99999********************************** PP
   S: 330  t.kgFel 335
           + +gF++
   Q: 3592 AnEGFGF 3598
           *9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de+++  +veMGF+r +a +aLr+   n++e A+++L+++
   Q: 1294 DESAISLIVEMGFSRARAEEALRQVgTNSVEIATDWLFSH 1333
           89************************************97 PP

Organism

Zea mays

Protein Sequence
(Fasta)

MAAAAAAHRA SFPLRLQQIL AGSRAVSPAI KVESEPPANV KAFIDQVINI PLHDIAIPLS 60
GFRWEFNKGN FHHWKPLFIH FDTYFKTYIS SRKDLLLSDD MTEAEPMPKN AILKILIVMQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACAATCACA ACCCTCTCTC TCCCTCTCCT TCACGTAGCC GCCTCTGAAT CCCCACCTCT 60
CTGCTCTCCC GTCGGCCTCC TCCGCGACCG ATGTGTGTGC CCCGCCGCCG GCCCAAAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR011987--ATPase_V1-cplx_hsu_C
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50237--HECT
PS50030--UBA

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	81.30	0.00e+00	3146.00
IUUC-Ani-009412	Aspergillus nidulans	33.22	2.00e-149	525.00
IUUC-Bol-015228	Brassica oleracea	55.53	0.00e+00	1858.00
IUUC-Bra-016726	Brassica rapa	54.19	0.00e+00	1934.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	32.82	9.00e-139	489.00
IUUC-Dor-030902	Dipodomys ordii	46.15	6.00e-108	387.00
IUUC-Fso-038464	Fusarium solani	32.03	5.00e-140	493.00
IUUC-Pop-099468	Populus trichocarpa	58.64	0.00e+00	2222.00
IUUC-Ppe-101641	Prunus persica	58.27	0.00e+00	2152.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	32.26	1.00e-140	495.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence