iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sar-112956

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Cullin-4A (Predicted)

Genbank Nucleotide ID

DP000765

Gene Name

CUL4A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSARG00000007838.1	ENSSART00000007845.1	ENSSARP00000007102.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	2.80e-129	432.0	327	576

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 354  ryiDqlLrksskglteeeleaqldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlk 442
           +++D++Lr+++k++t+eele++ldk++++f++i++kdvFe++Ykk+LakRLl+gksas +aE+s+++kLk+ecga+ftskLe+Mf+d++
   Q: 327  KHVDSKLRAGNKEATDEELERILDKIMIIFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLKHECGAAFTSKLEGMFKDME 415
           8**************************************************************************************** PP
   S: 443  vSedlnrqFkeekenteesesvelsvlvLsagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkgky 531
           +S+d++ +Fk+ ++n+++   ++l+v++L++g+Wpt++ +e v+LP+e+ k++e f++fYl khsgRkLqWq+tlg+a lkae+k+gk+
   Q: 416  LSKDIMVHFKQYMQNQSAPSPIDLTVNILTMGYWPTYTPME-VHLPPEMVKLQEVFKTFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKK 503
           *************************************9999.*********************************************** PP
   S: 532  elqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
           e+qVs fQ++vLL+fn+ + +s+ee+k at+++++eLrrtlqsL+++k++vl k+p++ke+e++d+f +N ef
   Q: 504  EFQVSLFQTLVLLMFNEGDGFSFEEIKVATGIEDSELRRTLQSLACGKARVLVKSPKGKEVEDGDKFLFNGEF 576
           **********************************************************************998 PP

Organism

Sorex araneus

Protein Sequence
(Fasta)

AVENLCSHKV SPALYKQLRQ VCEEHVQAQT LQFREYPFPX XXXXXXXXXX XXXXXXXXXX 60
XXXXXXXXXX XXXXXXXXXX XXXXXXXDMG LELFRNHIIS DKLVQSKTVD GILLLIERER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTTGAGA ATCTCTGCTC TCACAAAGTC TCGCCGGCTC TCTACAAGCA GCTCCGGCAG 60
GTGTGCGAGG AGCACGTGCA GGCGCAGACC CTTCAGTTCC GAGAATATCC TTTTCCTCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Interpro

IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007795	Ashbya gossypii	28.92	3.00e-39	156.00
IUUC-Acl-008359	Aspergillus clavatus	45.15	2.00e-80	293.00
IUUC-Afl-008567	Aspergillus flavus	50.15	9.00e-91	327.00
IUUC-Afu-008833	Aspergillus fumigatus	47.96	3.00e-91	329.00
IUUC-Ani-009373	Aspergillus nidulans	49.18	4.00e-94	338.00
IUUC-Ang-009622	Aspergillus niger	48.31	3.00e-90	326.00
IUUC-Aor-010241	Aspergillus oryzae	50.15	1.00e-90	327.00
IUUC-Ate-010251	Aspergillus terreus	51.03	1.00e-93	337.00
IUUC-Bgr-012219	Blumeria graminis	49.56	8.00e-86	311.00
IUUC-Bci-013744	Botrytis cinerea	51.03	4.00e-85	308.00
IUUC-Cel-018369	Caenorhabditis elegans	42.11	2.00e-75	276.00
IUUC-Cre-022739	Chlamydomonas reinhardtii	57.14	5.00e-105	374.00
IUUC-Cho-024899	Choloepus hoffmanni	95.99	0.00e+00	694.00
IUUC-Cgl-026761	Colletotrichum gloeosporioides	51.18	9.00e-94	337.00
IUUC-Cne-027026	Cryptococcus neoformans	41.99	2.00e-70	260.00
IUUC-Dse-031159	Dothistroma septosporum	47.16	7.00e-78	285.00
IUUC-Fox-037854	Fusarium oxysporum	52.06	2.00e-91	329.00
IUUC-Fso-038138	Fusarium solani	51.18	4.00e-90	325.00
IUUC-Ggr-040003	Gaeumannomyces graminis	46.31	3.00e-76	279.00
IUUC-Lma-053080	Leptosphaeria maculans	47.29	7.00e-85	308.00
IUUC-Mor-057102	Magnaporthe oryzae	48.10	1.00e-82	300.00
IUUC-Mpo-057342	Magnaporthe poae	47.16	4.00e-78	285.00
IUUC-Mla-058936	Melampsora laricipopulina	47.53	1.00e-82	300.00
IUUC-Nfi-068363	Neosartorya fischeri	48.23	5.00e-91	328.00
IUUC-Ncr-068950	Neurospora crassa	50.42	8.00e-92	331.00
IUUC-Opr-070671	Ochotona princeps	67.61	3.00e-114	405.00
IUUC-Pno-094946	Phaeosphaeria nodorum	47.35	3.00e-77	282.00
IUUC-Pop-099729	Populus trichocarpa	65.38	1.00e-112	398.00
IUUC-Ptt-103903	Puccinia triticina	45.13	2.00e-70	260.00
IUUC-Pte-104167	Pyrenophora teres	47.20	2.00e-85	310.00
IUUC-Pyt-104736	Pyrenophora triticirepentis	46.76	2.00e-83	302.00
IUUC-Ssl-108537	Sclerotinia sclerotiorum	51.33	2.00e-85	310.00
IUUC-Sre-114943	Sporisorium reilianum	49.17	4.00e-91	328.00
IUUC-Tsy-119517	Tarsius syrichta	89.11	0.00e+00	655.00
IUUC-Tre-121907	Trichoderma reesei	50.86	3.00e-94	338.00
IUUC-Tvi-122568	Trichoderma virens	51.16	3.00e-93	335.00
IUUC-Uma-129531	Ustilago maydis	49.17	8.00e-79	288.00
IUUC-Vda-129701	Verticillium dahliae	50.72	9.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence