iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094469

UUCD1 version

UUC-PeM-00540

Ensembl Protein ID

ENSPMAP00000001440.1

UniProt Accession

S4R8A9; S4R8A9_PETMA

Protein Name

Uncharacterized protein

Gene Name

USP34

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000001292.1	ENSPMAT00000001446.1	ENSPMAP00000001440.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-71	239.7	1954	2301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           +Gl+Nlg+tCYm S++Q+L++ip+ r+++++ k++ +        ++++ l +lqk+f+ l++s++ka++pr++ k   + +  +++
   Q: 1954 VGLTNLGATCYMASTIQQLYMIPQARQAVFTaKYTDD-------MKHKTTLFELQKMFTYLMESERKAYNPRSFCKNYMMDKLPLNT 2033
           6******************************333333.......345678889********************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
            eq+D  Ef++ l+ ++ee                               + k+++++lF+g ++++++ l+cd+vs++ e+f+++ 
   Q: 2034 GEQKDMTEFFTDLITKIEEMS----------------------------PELKNTVKTLFGGVITNNVVSLDCDHVSQTVEEFYTVR 2092
           *****************9977............................56789********************************* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLd 260
           ++v + +     ++ ++L++ t +++leg+n+y c++c kk++aek+  +kklP++L+++ +R++f+  ++++ek+n++++fpl+Ld
   Q: 2093 CQVADMK-----NIYESLDEVTVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILSFNTMRYTFNMVTMMKEKVNTHFSFPLRLD 2174
           *******.....9************************************************************************** PP
   S: 261  lspfcts.....................peekqkekkkYeLiavvvHsGslssGHYvayvkn.......ekgkWllfdDskVtevke 319
           ++p++++                        k +e+++Y+Li+v vH+G++++GHY++++++       +++kW+lf+D +V++ + 
   Q: 2175 MTPYTERwlmgrsdraeglkveegaggvA--KAEESYEYDLIGVTVHTGTADGGHYYSFIRDiinpaayRNNKWYLFNDAEVKPFDS 2259
           *******9999999888888887777542..22339**************************99999988999************** PP
   S: 320  eevleetg........................staYvlfYkr 337
           ++  +e+                         ++aY+lfYkr
   Q: 2260 TQLASECFggemttktydsvtdkfmdfsfektHSAYMLFYKR 2301
           ****97779*******************************98 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

MCDNCGELVS VLGARESEND EVSPLKKEHV LKLFNYISSW PQRQCLCCFK EYRNLEGFSQ 60
VLLELIRLAV SLVCCLRNSL QPSSLKPQPQ LDADMQMDFE VKDAPRLLDP TAGGAAARVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGACA ACTGCGGCGA GCTGGTGTCC GTGCTCGGCG CAAGTGAGTG AGGACGAGGG 60
AAACGGGCGG CAGCCTCCTT TAAATAGTCG CGGGAGAGTA CTCGGGAGAT TGCTGAGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002257	Ailuropoda melanoleuca	73.13	0.00e+00	4078.00
IUUC-Apl-003284	Anas platyrhynchos	73.73	0.00e+00	4102.00
IUUC-Aca-004415	Anolis carolinensis	73.67	0.00e+00	4073.00
IUUC-Acl-008140	Aspergillus clavatus	28.76	1.00e-61	231.00
IUUC-Afl-008381	Aspergillus flavus	30.64	3.00e-63	236.00
IUUC-Afu-008857	Aspergillus fumigatus	25.94	1.00e-62	234.00
IUUC-Ani-009257	Aspergillus nidulans	28.25	2.00e-52	200.00
IUUC-Ang-009759	Aspergillus niger	25.91	3.00e-59	223.00
IUUC-Aor-009931	Aspergillus oryzae	30.64	3.00e-63	236.00
IUUC-Ate-010246	Aspergillus terreus	24.81	6.00e-53	202.00
IUUC-Ame-011219	Astyanax mexicanus	61.02	0.00e+00	2040.00
IUUC-Bgr-012195	Blumeria graminis	26.53	3.00e-61	230.00
IUUC-Bta-012989	Bos taurus	73.43	0.00e+00	4070.00
IUUC-Bci-013798	Botrytis cinerea	33.78	1.00e-57	218.00
IUUC-Cja-018974	Callithrix jacchus	44.84	3.00e-90	323.00
IUUC-Cfa-021214	Canis familiaris	73.20	0.00e+00	4080.00
IUUC-Cpo-021912	Cavia porcellus	77.74	0.00e+00	2731.00
IUUC-Csa-023658	Chlorocebus sabaeus	73.23	0.00e+00	4080.00
IUUC-Cho-024971	Choloepus hoffmanni	60.52	0.00e+00	2260.00
IUUC-Cin-025147	Ciona intestinalis	34.19	2.00e-33	134.00
IUUC-Csv-025956	Ciona savignyi	24.20	5.00e-76	279.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	35.73	5.00e-63	236.00
IUUC-Dre-027428	Danio rerio	76.00	0.00e+00	3945.00
IUUC-Dno-029690	Dasypus novemcinctus	72.58	0.00e+00	4049.00
IUUC-Dor-030817	Dipodomys ordii	60.71	0.00e+00	1411.00
IUUC-Dse-031423	Dothistroma septosporum	25.98	1.00e-36	148.00
IUUC-Dme-032102	Drosophila melanogaster	53.83	0.00e+00	820.00
IUUC-Ete-032552	Echinops telfairi	70.53	0.00e+00	1971.00
IUUC-Eca-033457	Equus caballus	73.37	0.00e+00	4076.00
IUUC-Eeu-035118	Erinaceus europaeus	69.13	0.00e+00	2214.00
IUUC-Fca-036213	Felis catus	72.31	0.00e+00	3779.00
IUUC-Fal-037643	Ficedula albicollis	72.37	0.00e+00	4054.00
IUUC-Fox-037971	Fusarium oxysporum	26.43	2.00e-60	226.00
IUUC-Fso-038108	Fusarium solani	28.17	5.00e-60	226.00
IUUC-Ggr-040075	Gaeumannomyces graminis	32.72	2.00e-62	234.00
IUUC-Gga-040511	Gallus gallus	72.27	0.00e+00	4043.00
IUUC-Gac-042024	Gasterosteus aculeatus	78.08	0.00e+00	3647.00
IUUC-Ggo-044924	Gorilla gorilla	70.08	0.00e+00	3913.00
IUUC-Hsa-046913	Homo sapiens	73.20	0.00e+00	4080.00
IUUC-Itr-048626	Ictidomys tridecemlineatus	69.65	0.00e+00	4780.00
IUUC-Lch-049675	Latimeria chalumnae	72.42	0.00e+00	3117.00
IUUC-Loc-052832	Lepisosteus oculatus	73.23	0.00e+00	4047.00
IUUC-Lma-053130	Leptosphaeria maculans	27.37	7.00e-56	212.00
IUUC-Laf-054169	Loxodonta africana	73.21	0.00e+00	4092.00
IUUC-Mcc-055847	Macaca mulatta	72.04	0.00e+00	3990.00
IUUC-Meu-056327	Macropus eugenii	69.86	0.00e+00	1295.00
IUUC-Mor-057152	Magnaporthe oryzae	27.45	2.00e-62	234.00
IUUC-Mpo-057310	Magnaporthe poae	28.73	2.00e-63	237.00
IUUC-Mga-060159	Meleagris gallopavo	25.51	7.00e-74	272.00
IUUC-Mmr-060780	Microcebus murinus	73.26	0.00e+00	4098.00
IUUC-Mdo-062308	Monodelphis domestica	72.64	0.00e+00	4088.00
IUUC-Mmu-063457	Mus musculus	73.05	0.00e+00	4056.00
IUUC-Mpu-066917	Mustela putorius furo	71.07	0.00e+00	3908.00
IUUC-Mlu-067696	Myotis lucifugus	73.17	0.00e+00	4059.00
IUUC-Nfi-068259	Neosartorya fischeri	26.43	9.00e-62	231.00
IUUC-Ncr-068911	Neurospora crassa	28.78	3.00e-60	226.00
IUUC-Nle-069586	Nomascus leucogenys	73.20	0.00e+00	4081.00
IUUC-Opr-070447	Ochotona princeps	68.97	0.00e+00	2089.00
IUUC-Ont-072396	Oreochromis niloticus	75.91	0.00e+00	3976.00
IUUC-Oan-073147	Ornithorhynchus anatinus	73.48	0.00e+00	4108.00
IUUC-Ocu-074324	Oryctolagus cuniculus	72.76	0.00e+00	4064.00
IUUC-Ola-086312	Oryzias latipes	74.36	0.00e+00	3983.00
IUUC-Oga-088878	Otolemur garnettii	72.74	0.00e+00	4061.00
IUUC-Oar-089919	Ovis aries	73.33	0.00e+00	4064.00
IUUC-Ptr-090713	Pan troglodytes	77.39	0.00e+00	3935.00
IUUC-Pan-091957	Papio anubis	73.43	0.00e+00	3796.00
IUUC-Psi-093240	Pelodiscus sinensis	73.52	0.00e+00	4094.00
IUUC-Pno-095059	Phaeosphaeria nodorum	32.79	2.00e-56	213.00
IUUC-Pfo-097159	Poecilia formosa	74.83	0.00e+00	3992.00
IUUC-Pab-098003	Pongo abelii	72.92	0.00e+00	4061.00
IUUC-Pca-100799	Procavia capensis	85.02	0.00e+00	1330.00
IUUC-Pva-103226	Pteropus vampyrus	69.67	0.00e+00	3811.00
IUUC-Pte-104235	Pyrenophora teres	30.29	7.00e-56	212.00
IUUC-Pyt-104803	Pyrenophora triticirepentis	26.26	4.00e-57	215.00
IUUC-Rno-105389	Rattus norvegicus	73.01	0.00e+00	4063.00
IUUC-Sha-106979	Sarcophilus harrisii	73.29	0.00e+00	4100.00
IUUC-Smo-108879	Selaginella moellendorffii	28.79	6.00e-86	312.00
IUUC-Sar-113444	Sorex araneus	66.41	0.00e+00	3548.00
IUUC-Ssc-115815	Sus scrofa	77.60	0.00e+00	3474.00
IUUC-Tgu-117470	Taeniopygia guttata	73.41	0.00e+00	4051.00
IUUC-Tru-118543	Takifugu rubripes	74.95	0.00e+00	3960.00
IUUC-Tsy-119081	Tarsius syrichta	65.95	0.00e+00	3524.00
IUUC-Tni-120294	Tetraodon nigroviridis	77.53	2.00e-145	506.00
IUUC-Tre-122057	Trichoderma reesei	29.58	2.00e-61	230.00
IUUC-Tvi-122570	Trichoderma virens	32.06	8.00e-60	225.00
IUUC-Tme-127154	Tuber melanosporum	26.77	2.00e-61	229.00
IUUC-Tbe-127801	Tupaia belangeri	67.42	0.00e+00	2126.00
IUUC-Ttr-129262	Tursiops truncatus	69.52	0.00e+00	3822.00
IUUC-Vda-129686	Verticillium dahliae	28.90	3.00e-62	233.00
IUUC-Vpa-130484	Vicugna pacos	71.53	0.00e+00	3918.00
IUUC-Xtr-131769	Xenopus tropicalis	70.01	0.00e+00	3931.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence