iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pgr-103419

Ensembl Protein ID

EFP84801

UniProt Accession

E3KKH6; E3KKH6_PUCGT

Genbank Protein ID

EFP84801.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

DS178292

Gene Name

PGTG_10272

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGTG_10272	EFP84801	EFP84801

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	9.20e-58	195.8	3	309

Active Site

Position(s)	Description	Evidence
88	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
166	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAlls 106
           ++w+  esdP +ft l++++gv +  qveel+sLd ++l+++ +pv++l++lFk+ +  +   ++q         ++ +    +fa+qvi N+Cat A+l 
   Q: 3    EGWCLTESDPAIFTILLSELGVSGL-QVEELWSLDNQSLEQL-KPVHALIFLFKYVNSDQRDPSKQ------AGEQQPAPPGTWFAHQVITNACATLAILN 95
           68**********************9.****************.***********877555555444......3567889999******************* PP
   S: 107  vllncedkl..ldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgk 205
           ++ n  +    ++lG++ls+lke++   ++++ ++ l+n++ ++++hns+ar+++++++e +    +  t++a+hf++y + +g+lyeldgl+  P+ +gk
   Q: 96   AVMNIPSTSskIQLGQELSQLKEFSVDLDSQMTGELLTNSERIRAVHNSFARPDPFQRDEPK----QMSTEDAYHFITYLPLQGKLYELDGLNGLPVFHGK 192
           ****86555459*********************************************99877....3449******************************* PP
   S: 206  kketeelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydefic 306
             e + +++ ++ v+   +ri+ ++s e+ fnl+a++ dr  + + r   + +d              e+ +++++ e+ krk++  +   +++n  + i 
   Q: 193  IPEGQSWTSLAREVI--QNRINTYSSTEVHFNLMAVCEDRLNVLEERKASMTVDS----------MGYENLKMEIEAEEAKRKRWAEEVAIKRHNHIGLIH 281
           ***************..**********************7655555555555544..........4578899999999*********************** PP
   S: 307  ifikdlaregilrklve...etisevre 331
            ++  la++g l++ v+   +++  +++
   Q: 282  ALMVGLAKHGSLAERVNlakQKMVDRQR 309
           ***********99755411155555554 PP

Organism

Puccinia graminis

Protein Sequence
(Fasta)

MSEGWCLTES DPAIFTILLS ELGVSGLQVE ELWSLDNQSL EQLKPVHALI FLFKYVNSDQ 60
RDPSKQAGEQ QPAPPGTWFA HQVITNACAT LAILNAVMNI PSTSSKIQLG QELSQLKEFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTTACAAA GTTGGTGTCC GAATTCCCGG TCCACTCGAT TGTAGCAACT CTTCTCCAAC 60
AATCACACAC CGACAGCACG ATAACGGCTC CTATTTTAAG GTCTTCTTCG ATCGCAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

pgr:PGTG_10272

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	40.36	1.00e-62	231.00
IUUC-Aml-001866	Ailuropoda melanoleuca	40.57	1.00e-59	221.00
IUUC-Atr-002966	Amborella trichopoda	38.48	2.00e-52	197.00
IUUC-Apl-003306	Anas platyrhynchos	36.80	5.00e-54	202.00
IUUC-Aca-004763	Anolis carolinensis	40.88	6.00e-60	222.00
IUUC-Aly-005581	Arabidopsis lyrata	38.10	2.00e-51	194.00
IUUC-Ath-007283	Arabidopsis thaliana	37.98	4.00e-54	203.00
IUUC-Ago-007999	Ashbya gossypii	33.91	4.00e-38	150.00
IUUC-Acl-008231	Aspergillus clavatus	42.31	4.00e-45	173.00
IUUC-Afl-008557	Aspergillus flavus	39.37	1.00e-50	191.00
IUUC-Afu-008988	Aspergillus fumigatus	36.59	2.00e-46	177.00
IUUC-Ani-009420	Aspergillus nidulans	39.81	8.00e-54	202.00
IUUC-Ang-009859	Aspergillus niger	41.25	7.00e-44	169.00
IUUC-Aor-010145	Aspergillus oryzae	39.37	1.00e-50	191.00
IUUC-Ate-010347	Aspergillus terreus	34.80	7.00e-44	169.00
IUUC-Ame-010791	Astyanax mexicanus	40.43	6.00e-60	222.00
IUUC-Bgr-012298	Blumeria graminis	36.25	7.00e-44	169.00
IUUC-Bta-013251	Bos taurus	40.69	1.00e-59	221.00
IUUC-Bci-013786	Botrytis cinerea	37.72	9.00e-52	195.00
IUUC-Bdi-014132	Brachypodium distachyon	39.94	5.00e-59	219.00
IUUC-Bol-015611	Brassica oleracea	40.00	5.00e-53	199.00
IUUC-Bra-017769	Brassica rapa	39.70	3.00e-53	199.00
IUUC-Cel-018604	Caenorhabditis elegans	39.63	1.00e-58	218.00
IUUC-Cja-019768	Callithrix jacchus	36.60	1.00e-53	201.00
IUUC-Cfa-020207	Canis familiaris	40.57	1.00e-59	221.00
IUUC-Cpo-021925	Cavia porcellus	38.68	3.00e-55	206.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	35.62	5.00e-50	189.00
IUUC-Csa-023958	Chlorocebus sabaeus	40.57	6.00e-59	219.00
IUUC-Cho-024928	Choloepus hoffmanni	40.66	1.00e-10	58.50
IUUC-Cin-025771	Ciona intestinalis	38.75	1.00e-57	214.00
IUUC-Csv-026149	Ciona savignyi	41.38	1.00e-60	224.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	34.26	7.00e-44	169.00
IUUC-Cne-026955	Cryptococcus neoformans	43.13	5.00e-66	242.00
IUUC-Cme-027104	Cyanidioschyzon merolae	33.33	8.00e-44	169.00
IUUC-Dre-027409	Danio rerio	39.33	4.00e-59	219.00
IUUC-Dno-028921	Dasypus novemcinctus	40.57	1.00e-59	221.00
IUUC-Dor-030891	Dipodomys ordii	31.85	5.00e-32	131.00
IUUC-Dse-031170	Dothistroma septosporum	38.71	8.00e-55	205.00
IUUC-Dme-031677	Drosophila melanogaster	41.14	6.00e-66	242.00
IUUC-Ete-032646	Echinops telfairi	35.58	7.00e-31	127.00
IUUC-Eca-033776	Equus caballus	39.33	4.00e-52	196.00
IUUC-Eeu-035305	Erinaceus europaeus	39.13	1.00e-33	135.00
IUUC-Fca-035846	Felis catus	37.39	4.00e-55	206.00
IUUC-Fal-037597	Ficedula albicollis	40.67	6.00e-53	199.00
IUUC-Fox-037670	Fusarium oxysporum	36.36	8.00e-47	178.00
IUUC-Fso-038243	Fusarium solani	37.04	9.00e-48	182.00
IUUC-Gmo-038499	Gadus morhua	36.79	3.00e-51	193.00
IUUC-Ggr-039975	Gaeumannomyces graminis	32.57	5.00e-44	169.00
IUUC-Gga-040904	Gallus gallus	41.46	6.00e-62	229.00
IUUC-Gac-042058	Gasterosteus aculeatus	38.99	1.00e-56	211.00
IUUC-Gma-043030	Glycine max	40.77	2.00e-55	207.00
IUUC-Ggo-044699	Gorilla gorilla	44.94	2.00e-56	211.00
IUUC-Hsa-046227	Homo sapiens	40.44	2.00e-59	220.00
IUUC-Hvu-047359	Hordeum vulgare	40.36	3.00e-62	229.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	36.96	1.00e-54	205.00
IUUC-Lch-049829	Latimeria chalumnae	41.19	5.00e-61	226.00
IUUC-Lpe-050899	Leersia perrieri	39.94	9.00e-57	211.00
IUUC-Loc-052264	Lepisosteus oculatus	40.13	9.00e-58	215.00
IUUC-Lma-053110	Leptosphaeria maculans	37.58	3.00e-41	160.00
IUUC-Laf-053639	Loxodonta africana	40.57	1.00e-59	221.00
IUUC-Mcc-055506	Macaca mulatta	40.57	6.00e-59	219.00
IUUC-Meu-056267	Macropus eugenii	35.66	3.00e-37	148.00
IUUC-Mor-057001	Magnaporthe oryzae	33.92	1.00e-49	187.00
IUUC-Mpo-057608	Magnaporthe poae	39.78	6.00e-31	125.00
IUUC-Mtr-057731	Medicago truncatula	37.80	6.00e-55	205.00
IUUC-Mla-059016	Melampsora laricipopulina	68.81	4.00e-82	295.00
IUUC-Mga-060178	Meleagris gallopavo	40.32	6.00e-55	205.00
IUUC-Mvi-060353	Microbotryum violaceum	44.68	5.00e-64	236.00
IUUC-Mmr-060738	Microcebus murinus	40.44	2.00e-59	221.00
IUUC-Mdo-062266	Monodelphis domestica	45.62	9.00e-49	184.00
IUUC-Mmu-063619	Mus musculus	40.88	3.00e-59	220.00
IUUC-Mac-065301	Musa acuminata	41.21	2.00e-61	227.00
IUUC-Mpu-066058	Mustela putorius furo	40.57	8.00e-60	221.00
IUUC-Mlu-067292	Myotis lucifugus	40.57	2.00e-59	220.00
IUUC-Nfi-068275	Neosartorya fischeri	36.47	1.00e-50	191.00
IUUC-Ncr-068713	Neurospora crassa	39.53	8.00e-55	205.00
IUUC-Nle-069013	Nomascus leucogenys	40.57	3.00e-59	220.00
IUUC-Opr-070628	Ochotona princeps	36.34	1.00e-48	184.00
IUUC-Ont-072688	Oreochromis niloticus	40.00	1.00e-55	208.00
IUUC-Oan-073004	Ornithorhynchus anatinus	42.02	6.00e-50	188.00
IUUC-Ocu-074303	Oryctolagus cuniculus	40.57	2.00e-59	222.00
IUUC-Oba-075002	Oryza barthii	39.82	2.00e-58	217.00
IUUC-Obr-076392	Oryza brachyantha	46.25	1.00e-55	207.00
IUUC-Ogl-077271	Oryza glaberrima	39.82	2.00e-58	217.00
IUUC-Ogu-078493	Oryza glumaepatula	39.82	2.00e-58	217.00
IUUC-Oin-080084	Oryza indica	39.82	2.00e-58	217.00
IUUC-Olo-080803	Oryza longistaminata	39.82	1.00e-58	218.00
IUUC-Ome-081146	Oryza meridionalis	40.54	3.00e-60	223.00
IUUC-Oni-082146	Oryza nivara	39.82	2.00e-58	217.00
IUUC-Opu-083633	Oryza punctata	39.76	1.00e-56	211.00
IUUC-Oru-084789	Oryza rufipogon	39.82	2.00e-58	217.00
IUUC-Osa-086196	Oryza sativa	39.82	2.00e-58	217.00
IUUC-Ola-087126	Oryzias latipes	39.31	2.00e-57	214.00
IUUC-Olu-087665	Ostreococcus lucimarinus	39.57	4.00e-54	202.00
IUUC-Oga-089140	Otolemur garnettii	37.28	6.00e-55	206.00
IUUC-Oar-090296	Ovis aries	40.38	2.00e-58	217.00
IUUC-Ptr-090566	Pan troglodytes	40.44	2.00e-59	220.00
IUUC-Pan-092052	Papio anubis	40.57	6.00e-59	219.00
IUUC-Psi-093723	Pelodiscus sinensis	40.33	2.00e-52	197.00
IUUC-Pma-094568	Petromyzon marinus	41.55	6.00e-46	175.00
IUUC-Pno-095120	Phaeosphaeria nodorum	37.34	2.00e-43	167.00
IUUC-Ppa-095761	Physcomitrella patens	38.24	4.00e-54	203.00
IUUC-Pfo-096210	Poecilia formosa	39.62	3.00e-57	213.00
IUUC-Pab-098463	Pongo abelii	40.44	5.00e-59	219.00
IUUC-Pop-099109	Populus trichocarpa	38.89	4.00e-54	203.00
IUUC-Pca-100108	Procavia capensis	44.18	4.00e-54	203.00
IUUC-Ppe-101176	Prunus persica	39.30	4.00e-54	202.00
IUUC-Pva-102629	Pteropus vampyrus	45.34	1.00e-55	208.00
IUUC-Pte-104207	Pyrenophora teres	40.94	3.00e-27	112.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	37.28	2.00e-48	184.00
IUUC-Rno-105579	Rattus norvegicus	36.45	1.00e-47	181.00
IUUC-Sha-106894	Sarcophilus harrisii	38.21	2.00e-45	174.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	37.10	8.00e-51	192.00
IUUC-Spo-108371	Schizosaccharomyces pombe	40.97	8.00e-54	202.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	37.40	1.00e-39	154.00
IUUC-Smo-109396	Selaginella moellendorffii	39.70	6.00e-53	199.00
IUUC-Sit-110630	Setaria italica	40.84	4.00e-58	216.00
IUUC-Sly-110972	Solanum lycopersicum	38.53	3.00e-52	196.00
IUUC-Stu-112185	Solanum tuberosum	39.13	1.00e-59	221.00
IUUC-Sar-113294	Sorex araneus	35.36	1.00e-50	191.00
IUUC-Sbi-113951	Sorghum bicolor	48.12	4.00e-59	219.00
IUUC-Ssc-115501	Sus scrofa	39.16	6.00e-54	202.00
IUUC-Tgu-117152	Taeniopygia guttata	40.67	6.00e-53	199.00
IUUC-Tru-118388	Takifugu rubripes	39.31	2.00e-57	214.00
IUUC-Tsy-119109	Tarsius syrichta	40.44	2.00e-59	220.00
IUUC-Tni-120048	Tetraodon nigroviridis	39.31	6.00e-58	215.00
IUUC-Tca-121750	Theobroma cacao	38.48	4.00e-59	219.00
IUUC-Tre-122130	Trichoderma reesei	37.98	4.00e-48	183.00
IUUC-Tvi-122284	Trichoderma virens	39.30	4.00e-46	176.00
IUUC-Tae-124082	Triticum aestivum	40.36	2.00e-62	230.00
IUUC-Tur-126366	Triticum urartu	39.30	4.00e-39	153.00
IUUC-Tme-127187	Tuber melanosporum	39.81	3.00e-55	206.00
IUUC-Tbe-127705	Tupaia belangeri	35.52	7.00e-38	149.00
IUUC-Ttr-128867	Tursiops truncatus	39.53	1.00e-43	168.00
IUUC-Vda-129912	Verticillium dahliae	38.43	7.00e-50	189.00
IUUC-Vpa-130552	Vicugna pacos	45.62	1.00e-48	184.00
IUUC-Vvi-130881	Vitis vinifera	38.71	5.00e-56	209.00
IUUC-Xtr-131934	Xenopus tropicalis	39.94	4.00e-61	226.00
IUUC-Xma-133312	Xiphophorus maculatus	39.62	4.00e-57	213.00
IUUC-Yli-134487	Yarrowia lipolytica	37.37	5.00e-53	199.00
IUUC-Zma-135639	Zea mays	39.86	3.00e-48	183.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence