iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121750

Ensembl Protein ID

EOY09083

UniProt Accession

A0A061EWP2; A0A061EWP2_THECC

Genbank Protein ID

EOY09083.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

CM001883

Gene Name

TCM_024461

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_024461	EOY09081	EOY09081
TCM_024461	EOY09084	EOY09084
TCM_024461	EOY09083	EOY09083

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.10e-79	268.3	2	326

Active Site

Position(s)	Description	Evidence
83	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
158	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w+++esdPg+ft+l+++  vk++ qveelysLd + ++ + +pv+gl++lFk+ + ++ +r           v +d   ++ffa qvi+N+Cat+A+ls 
   Q: 2    SWCTIESDPGVFTELIQQMQVKGV-QVEELYSLDLDAVNNLSRPVYGLIFLFKWRPGEKDER----------LVIKDPNPNLFFASQVINNACATQAILSI 91
           7***********************.********************************99999..........44567789********************* PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkk.. 206
           l nc d   d+G++ls+lke+tk + pe k+la++n+++++ +hns+ar+e++  +e++++ +   +++++hf+sy++++g lyeldglk+ P+ lg++  
   Q: 92   LMNCPDI--DIGPELSKLKEFTKNFPPELKGLAINNSEAIRTAHNSFARPEPFVPEEQKAAGK---DDDVYHFISYIPVDGVLYELDGLKEGPISLGQCpt 187
           ******9..********************************************9888886665...9*******************************987 PP
   S: 207  .keteelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkid......................keLlkLlkdieseeekieaqlddek 284
            + + e+ + ++ v+   eri+ +++ eirfnl+a+ ++r+ ++t+ l+ l+                        + L k l++++s +e   +++  e+
   Q: 188  gQGDMEWMKMVQPVI--QERIERYSKSEIRFNLMAVIKNRKEMYTAELKELQKKrerilqqlatiqsdrladrssfEALNKQLSEVNSGIEGATEKILMEE 286
           777889999*****9..******************************987777789********************99*********************** PP
   S: 285  ekrkkfkiddirRtenydeficifikdlaregilrklvee 324
           ek kk+  ++irR++ny  f++ f+k la++++l+ l e+
   Q: 287  EKFKKWRTENIRRKHNYIPFLFNFLKILAEKKQLKPLIEK 326
           ***********************************99987 PP

Organism

Theobroma cacao

Protein Sequence
(Fasta)

MSWCTIESDP GVFTELIQQM QVKGVQVEEL YSLDLDAVNN LSRPVYGLIF LFKWRPGEKD 60
ERLVIKDPNP NLFFASQVIN NACATQAILS ILMNCPDIDI GPELSKLKEF TKNFPPELKG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAGTTTTA GGTATTTCTT AGTTTTTATA TTCTTCTCGT TTGCAATTTT TAAACAATTT 60
ACTGTTTGTG TGCTGCAGGC GGCAGCTGCT AATATCTCAT CATGTCTTGG TGCACGATTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	74.70	1.00e-143	501.00
IUUC-Aml-001866	Ailuropoda melanoleuca	49.24	1.00e-85	308.00
IUUC-Atr-002966	Amborella trichopoda	77.61	5.00e-151	526.00
IUUC-Apl-003306	Anas platyrhynchos	46.54	1.00e-79	289.00
IUUC-Aca-004763	Anolis carolinensis	50.15	1.00e-84	305.00
IUUC-Aly-005581	Arabidopsis lyrata	79.10	4.00e-141	493.00
IUUC-Ath-007283	Arabidopsis thaliana	78.21	9.00e-144	501.00
IUUC-Ago-007999	Ashbya gossypii	35.53	2.00e-33	135.00
IUUC-Acl-008231	Aspergillus clavatus	52.52	5.00e-63	233.00
IUUC-Afl-008557	Aspergillus flavus	48.66	6.00e-60	223.00
IUUC-Afu-008988	Aspergillus fumigatus	52.30	3.00e-61	227.00
IUUC-Ani-009420	Aspergillus nidulans	41.16	7.00e-61	226.00
IUUC-Ang-009859	Aspergillus niger	43.91	1.00e-58	218.00
IUUC-Aor-010145	Aspergillus oryzae	48.66	6.00e-60	223.00
IUUC-Ate-010347	Aspergillus terreus	42.41	2.00e-60	224.00
IUUC-Ame-010791	Astyanax mexicanus	49.41	6.00e-89	319.00
IUUC-Bgr-012298	Blumeria graminis	39.16	1.00e-56	212.00
IUUC-Bta-013251	Bos taurus	50.46	6.00e-86	309.00
IUUC-Bci-013786	Botrytis cinerea	40.17	8.00e-62	229.00
IUUC-Bdi-014132	Brachypodium distachyon	75.15	5.00e-139	486.00
IUUC-Bol-015611	Brassica oleracea	77.31	6.00e-145	506.00
IUUC-Bra-017769	Brassica rapa	77.31	4.00e-144	503.00
IUUC-Cel-018604	Caenorhabditis elegans	43.03	4.00e-72	263.00
IUUC-Cja-019768	Callithrix jacchus	45.07	5.00e-80	290.00
IUUC-Cfa-020207	Canis familiaris	49.24	1.00e-85	308.00
IUUC-Cpo-021925	Cavia porcellus	46.48	3.00e-79	287.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	49.54	5.00e-83	300.00
IUUC-Csa-023958	Chlorocebus sabaeus	50.15	1.00e-85	309.00
IUUC-Cho-024928	Choloepus hoffmanni	56.76	4.00e-20	90.90
IUUC-Cin-025771	Ciona intestinalis	42.81	7.00e-67	246.00
IUUC-Csv-026149	Ciona savignyi	43.40	1.00e-71	262.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	36.02	3.00e-48	184.00
IUUC-Cne-026955	Cryptococcus neoformans	31.36	1.00e-42	165.00
IUUC-Cme-027104	Cyanidioschyzon merolae	31.48	1.00e-47	182.00
IUUC-Dre-027409	Danio rerio	49.11	1.00e-88	318.00
IUUC-Dno-028921	Dasypus novemcinctus	48.62	2.00e-85	307.00
IUUC-Dor-030891	Dipodomys ordii	47.46	4.00e-40	158.00
IUUC-Dse-031170	Dothistroma septosporum	37.82	2.00e-57	214.00
IUUC-Dme-031677	Drosophila melanogaster	47.29	2.00e-80	291.00
IUUC-Ete-032646	Echinops telfairi	46.15	3.00e-47	182.00
IUUC-Eca-033776	Equus caballus	48.21	8.00e-77	279.00
IUUC-Eeu-035305	Erinaceus europaeus	44.51	7.00e-41	160.00
IUUC-Fca-035846	Felis catus	45.48	8.00e-81	293.00
IUUC-Fal-037597	Ficedula albicollis	48.53	2.00e-74	271.00
IUUC-Fox-037670	Fusarium oxysporum	45.61	4.00e-52	197.00
IUUC-Fso-038243	Fusarium solani	46.44	2.00e-52	198.00
IUUC-Gmo-038499	Gadus morhua	46.48	4.00e-78	283.00
IUUC-Ggr-039975	Gaeumannomyces graminis	45.78	4.00e-52	197.00
IUUC-Gga-040904	Gallus gallus	49.41	3.00e-89	320.00
IUUC-Gac-042058	Gasterosteus aculeatus	49.85	3.00e-86	310.00
IUUC-Gma-043030	Glycine max	91.64	5.00e-177	612.00
IUUC-Ggo-044699	Gorilla gorilla	45.77	1.00e-73	268.00
IUUC-Hsa-046227	Homo sapiens	49.24	1.00e-85	308.00
IUUC-Hvu-047359	Hordeum vulgare	74.85	7.00e-142	495.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	44.97	4.00e-80	290.00
IUUC-Lch-049829	Latimeria chalumnae	49.24	1.00e-85	308.00
IUUC-Lpe-050899	Leersia perrieri	75.69	5.00e-135	473.00
IUUC-Loc-052264	Lepisosteus oculatus	49.09	2.00e-83	301.00
IUUC-Lma-053110	Leptosphaeria maculans	49.34	5.00e-53	201.00
IUUC-Laf-053639	Loxodonta africana	49.24	1.00e-85	308.00
IUUC-Mcc-055506	Macaca mulatta	50.15	1.00e-85	309.00
IUUC-Meu-056267	Macropus eugenii	45.04	3.00e-53	202.00
IUUC-Mor-057001	Magnaporthe oryzae	45.12	1.00e-55	209.00
IUUC-Mpo-057608	Magnaporthe poae	45.74	8.00e-36	142.00
IUUC-Mtr-057731	Medicago truncatula	87.46	9.00e-164	568.00
IUUC-Mla-059016	Melampsora laricipopulina	44.83	5.00e-44	169.00
IUUC-Mga-060178	Meleagris gallopavo	49.69	2.00e-80	291.00
IUUC-Mvi-060353	Microbotryum violaceum	38.14	3.00e-54	204.00
IUUC-Mmr-060738	Microcebus murinus	49.54	7.00e-86	309.00
IUUC-Mdo-062266	Monodelphis domestica	52.63	2.00e-61	227.00
IUUC-Mmu-063619	Mus musculus	49.24	3.00e-85	307.00
IUUC-Mac-065301	Musa acuminata	82.78	2.00e-161	560.00
IUUC-Mpu-066058	Mustela putorius furo	48.93	3.00e-85	307.00
IUUC-Mlu-067292	Myotis lucifugus	48.93	1.00e-84	305.00
IUUC-Nfi-068275	Neosartorya fischeri	41.48	2.00e-62	231.00
IUUC-Ncr-068713	Neurospora crassa	39.47	4.00e-58	217.00
IUUC-Nle-069013	Nomascus leucogenys	50.15	7.00e-86	310.00
IUUC-Opr-070628	Ochotona princeps	43.06	2.00e-74	271.00
IUUC-Ont-072688	Oreochromis niloticus	49.09	8.00e-85	306.00
IUUC-Oan-073004	Ornithorhynchus anatinus	52.04	3.00e-64	237.00
IUUC-Ocu-074303	Oryctolagus cuniculus	48.93	4.00e-85	308.00
IUUC-Oba-075002	Oryza barthii	76.65	2.00e-141	493.00
IUUC-Obr-076392	Oryza brachyantha	75.38	4.00e-137	479.00
IUUC-Ogl-077271	Oryza glaberrima	76.65	2.00e-141	493.00
IUUC-Ogu-078493	Oryza glumaepatula	76.95	1.00e-142	498.00
IUUC-Oin-080084	Oryza indica	76.95	1.00e-142	498.00
IUUC-Olo-080803	Oryza longistaminata	76.65	3.00e-142	496.00
IUUC-Ome-081146	Oryza meridionalis	76.35	4.00e-141	493.00
IUUC-Oni-082146	Oryza nivara	76.95	1.00e-142	498.00
IUUC-Opu-083633	Oryza punctata	76.92	8.00e-137	478.00
IUUC-Oru-084789	Oryza rufipogon	76.95	1.00e-142	498.00
IUUC-Osa-086196	Oryza sativa	76.95	1.00e-142	498.00
IUUC-Ola-087126	Oryzias latipes	48.01	2.00e-84	305.00
IUUC-Olu-087665	Ostreococcus lucimarinus	43.97	4.00e-73	266.00
IUUC-Oga-089140	Otolemur garnettii	45.76	5.00e-81	293.00
IUUC-Oar-090296	Ovis aries	49.08	2.00e-84	305.00
IUUC-Ptr-090566	Pan troglodytes	49.24	1.00e-85	308.00
IUUC-Pan-092052	Papio anubis	50.15	1.00e-85	309.00
IUUC-Psi-093723	Pelodiscus sinensis	49.84	3.00e-77	281.00
IUUC-Pma-094568	Petromyzon marinus	49.32	2.00e-61	228.00
IUUC-Pno-095120	Phaeosphaeria nodorum	50.65	4.00e-55	207.00
IUUC-Ppa-095761	Physcomitrella patens	72.01	4.00e-138	483.00
IUUC-Pfo-096210	Poecilia formosa	49.54	5.00e-86	310.00
IUUC-Pab-098463	Pongo abelii	49.24	1.00e-85	309.00
IUUC-Pop-099109	Populus trichocarpa	86.27	2.00e-170	590.00
IUUC-Pca-100108	Procavia capensis	52.07	1.00e-69	255.00
IUUC-Ppe-101176	Prunus persica	90.45	9.00e-175	605.00
IUUC-Pva-102629	Pteropus vampyrus	51.65	3.00e-71	261.00
IUUC-Pgr-103419	Puccinia graminis	45.80	6.00e-55	206.00
IUUC-Pte-104207	Pyrenophora teres	52.10	3.00e-38	149.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	50.43	4.00e-57	214.00
IUUC-Rno-105579	Rattus norvegicus	44.15	6.00e-73	266.00
IUUC-Sha-106894	Sarcophilus harrisii	50.17	3.00e-75	274.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	41.88	2.00e-62	231.00
IUUC-Spo-108371	Schizosaccharomyces pombe	41.64	3.00e-69	254.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	37.58	5.00e-49	186.00
IUUC-Smo-109396	Selaginella moellendorffii	75.30	2.00e-137	480.00
IUUC-Sit-110630	Setaria italica	75.75	2.00e-142	497.00
IUUC-Sly-110972	Solanum lycopersicum	87.34	8.00e-166	575.00
IUUC-Stu-112185	Solanum tuberosum	88.06	2.00e-178	617.00
IUUC-Sar-113294	Sorex araneus	43.06	6.00e-74	270.00
IUUC-Sbi-113951	Sorghum bicolor	75.75	2.00e-142	497.00
IUUC-Ssc-115501	Sus scrofa	47.48	1.00e-78	285.00
IUUC-Tgu-117152	Taeniopygia guttata	48.53	2.00e-74	271.00
IUUC-Tru-118388	Takifugu rubripes	49.54	2.00e-86	311.00
IUUC-Tsy-119109	Tarsius syrichta	49.24	1.00e-85	308.00
IUUC-Tni-120048	Tetraodon nigroviridis	49.54	2.00e-86	311.00
IUUC-Tre-122130	Trichoderma reesei	37.97	7.00e-54	203.00
IUUC-Tvi-122284	Trichoderma virens	39.30	3.00e-53	201.00
IUUC-Tae-124082	Triticum aestivum	75.15	3.00e-143	500.00
IUUC-Tur-126366	Triticum urartu	66.56	7.00e-110	389.00
IUUC-Tme-127187	Tuber melanosporum	41.89	3.00e-68	251.00
IUUC-Tbe-127619	Tupaia belangeri	43.00	6.00e-58	216.00
IUUC-Ttr-128867	Tursiops truncatus	45.97	1.00e-58	219.00
IUUC-Vda-129912	Verticillium dahliae	37.70	4.00e-54	204.00
IUUC-Vpa-130552	Vicugna pacos	53.37	7.00e-61	226.00
IUUC-Vvi-130881	Vitis vinifera	89.85	2.00e-175	607.00
IUUC-Xtr-131934	Xenopus tropicalis	48.24	1.00e-87	315.00
IUUC-Xma-133312	Xiphophorus maculatus	49.54	6.00e-86	309.00
IUUC-Yli-134487	Yarrowia lipolytica	33.72	2.00e-52	198.00
IUUC-Zma-135462	Zea mays	65.27	2.00e-117	414.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence